DE602004025119D1 - Neue derivate von 4,4'-dithiobis-(3-aminobutan-1-sulfonaten) und diese enthaltende zusammensetzungen - Google Patents
Neue derivate von 4,4'-dithiobis-(3-aminobutan-1-sulfonaten) und diese enthaltende zusammensetzungenInfo
- Publication number
- DE602004025119D1 DE602004025119D1 DE602004025119T DE602004025119T DE602004025119D1 DE 602004025119 D1 DE602004025119 D1 DE 602004025119D1 DE 602004025119 T DE602004025119 T DE 602004025119T DE 602004025119 T DE602004025119 T DE 602004025119T DE 602004025119 D1 DE602004025119 D1 DE 602004025119D1
- Authority
- DE
- Germany
- Prior art keywords
- dithiobis
- aminobutan
- sulphonate
- compositions containing
- new derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- HJPXZXVKLGEMGP-UHFFFAOYSA-N 3-amino-4-[(2-amino-4-sulfobutyl)disulfanyl]butane-1-sulfonic acid Chemical class OS(=O)(=O)CCC(N)CSSCC(N)CCS(O)(=O)=O HJPXZXVKLGEMGP-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 208000037849 arterial hypertension Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
- C07C323/66—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfo, esterified sulfo or halosulfonyl groups, bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/32—Esters thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0309700A FR2858617A1 (fr) | 2003-08-06 | 2003-08-06 | Derives de 4',4'-dithiobis-(3-aminobutane-1-sulfonate-1- sulfonates) nouveaux et compositions les contenant |
PCT/FR2004/002106 WO2005014535A1 (fr) | 2003-08-06 | 2004-08-06 | Derives de 4,4’-dithiobis-(3-aminobutane-1-sulfonates) nouveaux et compositions les contenant |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602004025119D1 true DE602004025119D1 (de) | 2010-03-04 |
Family
ID=34073059
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004025119T Active DE602004025119D1 (de) | 2003-08-06 | 2004-08-06 | Neue derivate von 4,4'-dithiobis-(3-aminobutan-1-sulfonaten) und diese enthaltende zusammensetzungen |
Country Status (14)
Country | Link |
---|---|
US (1) | US7582797B2 (de) |
EP (1) | EP1651596B1 (de) |
JP (1) | JP4718461B2 (de) |
AT (1) | ATE455097T1 (de) |
CA (1) | CA2533432C (de) |
CY (1) | CY1109950T1 (de) |
DE (1) | DE602004025119D1 (de) |
DK (1) | DK1651596T3 (de) |
ES (1) | ES2339354T3 (de) |
FR (1) | FR2858617A1 (de) |
PL (1) | PL1651596T3 (de) |
PT (1) | PT1651596E (de) |
SI (1) | SI1651596T1 (de) |
WO (1) | WO2005014535A1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2931151A1 (fr) * | 2008-05-13 | 2009-11-20 | Pharmaleads Soc Par Actions Si | Nouveaux derives d'amino-acides, leur procede de preparation et leur utilisation therapeutique |
CN102171185A (zh) | 2008-08-01 | 2011-08-31 | 拜奥西尼斯医药股份有限公司 | 甲硫氨酸类似物及其使用方法 |
EP2439192A1 (de) * | 2010-10-07 | 2012-04-11 | Quantum Genomics | Verfahren zur Herstellung von (3S,3S') 4,4'-disulfandiylbis (3-aminobutan 1-sulfonsäure) |
CN109464432A (zh) * | 2011-12-21 | 2019-03-15 | 量子基因公司 | (3s,3s’)4,4’-二硫烷二基双(3-氨基丁烷1-磺酸)和第二抗高血压药的组合 |
EP2722327A1 (de) * | 2012-10-22 | 2014-04-23 | Quantum Genomics | Kristalline Phase von (3S,3S') 4,4'-disulfandiylbis (3-Aminobutan 1-Sulfonsäure) mit L-Lysin |
US20170240570A1 (en) * | 2014-10-17 | 2017-08-24 | University Of Florida Research Foundation | Novel small molecule anticancer agents |
TW202100146A (zh) * | 2019-03-11 | 2021-01-01 | 法商量子基因科技有限公司 | 用於治療高血壓或心衰竭的化合物及包含其之組成物 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CO5021134A1 (es) * | 1998-05-01 | 2001-03-27 | Abbott Lab | Inhibidores beta-aminoacidos substituidos de aminopeptida- sa-2 metionina |
US6919307B2 (en) * | 2000-11-01 | 2005-07-19 | Praecis Pharmaceuticals, Inc. | Therapeutic agents and methods of use thereof for the modulation of angiogenesis |
EP1381360A4 (de) * | 2001-03-29 | 2009-12-02 | Smithkline Beecham Corp | Verbindungen und Verfahren zur Hemmung von MetAP2 in Säugern |
-
2003
- 2003-08-06 FR FR0309700A patent/FR2858617A1/fr not_active Withdrawn
-
2004
- 2004-08-06 PT PT04786279T patent/PT1651596E/pt unknown
- 2004-08-06 US US10/567,362 patent/US7582797B2/en active Active
- 2004-08-06 ES ES04786279T patent/ES2339354T3/es active Active
- 2004-08-06 EP EP04786279A patent/EP1651596B1/de active Active
- 2004-08-06 AT AT04786279T patent/ATE455097T1/de active
- 2004-08-06 PL PL04786279T patent/PL1651596T3/pl unknown
- 2004-08-06 DK DK04786279.2T patent/DK1651596T3/da active
- 2004-08-06 WO PCT/FR2004/002106 patent/WO2005014535A1/fr active Application Filing
- 2004-08-06 JP JP2006522380A patent/JP4718461B2/ja not_active Expired - Fee Related
- 2004-08-06 DE DE602004025119T patent/DE602004025119D1/de active Active
- 2004-08-06 SI SI200431385T patent/SI1651596T1/sl unknown
- 2004-08-06 CA CA2533432A patent/CA2533432C/fr not_active Expired - Fee Related
-
2010
- 2010-03-23 CY CY20101100285T patent/CY1109950T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
US20060205695A1 (en) | 2006-09-14 |
JP2007501204A (ja) | 2007-01-25 |
JP4718461B2 (ja) | 2011-07-06 |
CA2533432A1 (fr) | 2005-02-17 |
EP1651596B1 (de) | 2010-01-13 |
DK1651596T3 (da) | 2010-05-10 |
CA2533432C (fr) | 2013-05-21 |
PT1651596E (pt) | 2010-04-16 |
PL1651596T3 (pl) | 2010-08-31 |
ATE455097T1 (de) | 2010-01-15 |
US7582797B2 (en) | 2009-09-01 |
ES2339354T3 (es) | 2010-05-19 |
FR2858617A1 (fr) | 2005-02-11 |
EP1651596A1 (de) | 2006-05-03 |
WO2005014535A1 (fr) | 2005-02-17 |
CY1109950T1 (el) | 2014-09-10 |
SI1651596T1 (sl) | 2010-06-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |