DE602004018496D1 - Pharmazeutische zubereitung zur intranasalen applikation von proteinen, enthaltend chitosan oder eines seiner derivate - Google Patents

Pharmazeutische zubereitung zur intranasalen applikation von proteinen, enthaltend chitosan oder eines seiner derivate

Info

Publication number
DE602004018496D1
DE602004018496D1 DE602004018496T DE602004018496T DE602004018496D1 DE 602004018496 D1 DE602004018496 D1 DE 602004018496D1 DE 602004018496 T DE602004018496 T DE 602004018496T DE 602004018496 T DE602004018496 T DE 602004018496T DE 602004018496 D1 DE602004018496 D1 DE 602004018496D1
Authority
DE
Germany
Prior art keywords
derivatives
pharmaceutical preparation
proteins containing
containing chitosan
intranasal application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004018496T
Other languages
English (en)
Inventor
Ann Margaret Dyer
Peter James Watts
Yu-Hui Cheng
Alan Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyowa Kirin Services Ltd
Original Assignee
Archimedes Development Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Archimedes Development Ltd filed Critical Archimedes Development Ltd
Publication of DE602004018496D1 publication Critical patent/DE602004018496D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE602004018496T 2003-07-04 2004-07-02 Pharmazeutische zubereitung zur intranasalen applikation von proteinen, enthaltend chitosan oder eines seiner derivate Expired - Lifetime DE602004018496D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0315632.0A GB0315632D0 (en) 2003-07-04 2003-07-04 Pharmaceutical formulations
PCT/GB2004/002876 WO2005004838A1 (en) 2003-07-04 2004-07-02 Pharmaceutical formulations for intranasal administration of protein comprising a chitosan or a derivative thereof

Publications (1)

Publication Number Publication Date
DE602004018496D1 true DE602004018496D1 (de) 2009-01-29

Family

ID=27741549

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004018496T Expired - Lifetime DE602004018496D1 (de) 2003-07-04 2004-07-02 Pharmazeutische zubereitung zur intranasalen applikation von proteinen, enthaltend chitosan oder eines seiner derivate

Country Status (14)

Country Link
US (2) US7662403B2 (de)
EP (1) EP1641434B1 (de)
AT (1) ATE417599T1 (de)
AU (1) AU2004255515B2 (de)
CA (1) CA2531239C (de)
DE (1) DE602004018496D1 (de)
DK (1) DK1641434T3 (de)
ES (1) ES2319995T3 (de)
GB (1) GB0315632D0 (de)
NZ (1) NZ544718A (de)
PL (1) PL1641434T3 (de)
PT (1) PT1641434E (de)
WO (1) WO2005004838A1 (de)
ZA (1) ZA200600027B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0315632D0 (en) 2003-07-04 2003-08-13 West Pharm Serv Drug Res Ltd Pharmaceutical formulations
US20090136505A1 (en) * 2005-02-23 2009-05-28 Johanna Bentz Intranasal Administration of Active Agents to the Central Nervous System
GB2438834A (en) 2006-06-08 2007-12-12 Optinose As Intranasal protein administration
US8637469B2 (en) * 2006-07-11 2014-01-28 Roy C. Levitt Rhinosinusitis prevention and therapy with proinflammatory cytokine inhibitors
US20080182819A1 (en) * 2007-01-29 2008-07-31 Act Iii Licensing, Llc Chitosan compositions and methods for using chitosan compositions in the treatment of health disorders
GB0812742D0 (en) 2008-07-11 2008-08-20 Critical Pharmaceuticals Ltd Process
AU2009313998B2 (en) * 2008-11-12 2016-06-16 Synedgen, Inc. Chitosan derivatives to treat animals or optimize animal health
EP2782590A4 (de) * 2011-11-23 2016-08-03 Durect Corp Biologisch abbaubare und mittels strahlung sterilisierte arzneimittelabgabezusammensetzungen
GB201319437D0 (en) * 2013-11-04 2013-12-18 Nanomerics Ltd Delivery of drugs
US20160303242A1 (en) 2013-12-09 2016-10-20 Durect Corporation Pharmaceutically Active Agent Complexes, Polymer Complexes, and Compositions and Methods Involving the Same
EP3250214B1 (de) * 2015-02-01 2021-09-01 Syros Pharmaceuticals, Inc. Lyophilisierte zusammensetzungen mit hohem oberflächenbereich mit arsen zur oralen verabreichung an patienten
WO2019245373A1 (en) 2018-06-22 2019-12-26 Bioralix B.V. Formulations of biological polymers for oral administration

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5690954A (en) * 1987-05-22 1997-11-25 Danbiosyst Uk Limited Enhanced uptake drug delivery system having microspheres containing an active drug and a bioavailability improving material
GB8904370D0 (en) 1989-02-25 1989-04-12 Cosmas Damian Ltd Liquid delivery compositions
JPH07118170A (ja) * 1993-10-19 1995-05-09 Dot:Kk 経鼻吸収薬物用キャリヤ、生理活性ペプチド組成物およびその製造法
US20010053359A1 (en) * 1994-07-26 2001-12-20 Peter Watts Drug delivery composition for the nasal administration of antiviral agents
GB9416884D0 (en) 1994-08-20 1994-10-12 Danbiosyst Uk Drug delivery compositions
GB9419979D0 (en) 1994-10-04 1994-11-16 Medeva Holdings Bv Vaccine compositions
SE9403905D0 (sv) * 1994-11-14 1994-11-14 Astra Ab New formulations
GB9522351D0 (en) 1995-11-01 1996-01-03 Medeva Holdings Bv Vaccine compositions
GB9525083D0 (en) 1995-12-07 1996-02-07 Danbiosyst Uk Vaccine compositions
EP0943326B2 (de) 1996-02-27 2006-12-20 Teijin Limited Puderförmige zusammensetzung zur nasalen anwendung
US5912014A (en) * 1996-03-15 1999-06-15 Unigene Laboratories, Inc. Oral salmon calcitonin pharmaceutical products
WO1998001160A2 (en) 1996-07-10 1998-01-15 Danbiosyst Uk Limited Compositions suitable for delivery of genes to epithelial cells
GB9700624D0 (en) * 1997-01-14 1997-03-05 Danbiosyst Uk Drug delivery composition
GB9707934D0 (en) * 1997-04-18 1997-06-04 Danbiosyst Uk Improved delivery of drugs to mucosal surfaces
GB9713980D0 (en) 1997-07-03 1997-09-10 Danbiosyst Uk New conjugates
GB9725084D0 (en) 1997-11-28 1998-01-28 Medeva Europ Ltd Vaccine compositions
BR9911890A (pt) * 1998-07-08 2001-03-27 Kirin Amgen Inc Preparado contendo produto medicinal de elevado peso molecular na forma em pó para administração através da mucosa
SE9803239D0 (sv) 1998-09-24 1998-09-24 Diabact Ab Composition for the treatment of acute pain
GB9924797D0 (en) * 1999-10-20 1999-12-22 West Pharm Serv Drug Res Ltd Compound
US20020013331A1 (en) 2000-06-26 2002-01-31 Williams Robert O. Methods and compositions for treating pain of the mucous membrane
SI1307194T2 (sl) 2000-07-31 2011-07-29 Nycomed Danmark Aps Sestavek fentanila za nazalno dejanje
AU2002346424A1 (en) * 2001-11-19 2003-06-10 Becton, Dickinson And Company Pharmaceutical compositions in particulate form
US7666876B2 (en) 2002-03-19 2010-02-23 Vernalis (R&D) Limited Buprenorphine formulations for intranasal delivery
GB0300531D0 (en) 2003-01-10 2003-02-12 West Pharm Serv Drug Res Ltd Pharmaceutical compositions
GB0315632D0 (en) 2003-07-04 2003-08-13 West Pharm Serv Drug Res Ltd Pharmaceutical formulations

Also Published As

Publication number Publication date
AU2004255515A1 (en) 2005-01-20
US8481070B2 (en) 2013-07-09
CA2531239C (en) 2011-05-24
NZ544718A (en) 2009-06-26
AU2004255515A2 (en) 2005-01-20
ES2319995T3 (es) 2009-05-18
AU2004255515B2 (en) 2009-04-30
ZA200600027B (en) 2009-08-26
CA2531239A1 (en) 2005-01-20
PT1641434E (pt) 2009-03-19
EP1641434A1 (de) 2006-04-05
DK1641434T3 (da) 2009-04-06
GB0315632D0 (en) 2003-08-13
US20100021553A1 (en) 2010-01-28
US7662403B2 (en) 2010-02-16
ATE417599T1 (de) 2009-01-15
WO2005004838A1 (en) 2005-01-20
PL1641434T3 (pl) 2009-08-31
US20060120973A1 (en) 2006-06-08
WO2005004838A8 (en) 2005-03-17
EP1641434B1 (de) 2008-12-17

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Legal Events

Date Code Title Description
8328 Change in the person/name/address of the agent

Representative=s name: STROHSCHAENK UND KOLLEGEN, 85521 OTTOBRUNN

8364 No opposition during term of opposition