ATE417599T1 - Pharmazeutische zubereitung zur intranasalen applikation von proteinen, enthaltend chitosan oder eines seiner derivate - Google Patents

Pharmazeutische zubereitung zur intranasalen applikation von proteinen, enthaltend chitosan oder eines seiner derivate

Info

Publication number
ATE417599T1
ATE417599T1 AT04743222T AT04743222T ATE417599T1 AT E417599 T1 ATE417599 T1 AT E417599T1 AT 04743222 T AT04743222 T AT 04743222T AT 04743222 T AT04743222 T AT 04743222T AT E417599 T1 ATE417599 T1 AT E417599T1
Authority
AT
Austria
Prior art keywords
proteins
derivatives
pharmaceutical preparation
containing chitosan
intranasal application
Prior art date
Application number
AT04743222T
Other languages
English (en)
Inventor
Ann Margaret Dyer
Peter James Watts
Yu-Hui Cheng
Alan Smith
Original Assignee
Archimedes Dev Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Archimedes Dev Ltd filed Critical Archimedes Dev Ltd
Application granted granted Critical
Publication of ATE417599T1 publication Critical patent/ATE417599T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT04743222T 2003-07-04 2004-07-02 Pharmazeutische zubereitung zur intranasalen applikation von proteinen, enthaltend chitosan oder eines seiner derivate ATE417599T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0315632.0A GB0315632D0 (en) 2003-07-04 2003-07-04 Pharmaceutical formulations

Publications (1)

Publication Number Publication Date
ATE417599T1 true ATE417599T1 (de) 2009-01-15

Family

ID=27741549

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04743222T ATE417599T1 (de) 2003-07-04 2004-07-02 Pharmazeutische zubereitung zur intranasalen applikation von proteinen, enthaltend chitosan oder eines seiner derivate

Country Status (14)

Country Link
US (2) US7662403B2 (de)
EP (1) EP1641434B1 (de)
AT (1) ATE417599T1 (de)
AU (1) AU2004255515B2 (de)
CA (1) CA2531239C (de)
DE (1) DE602004018496D1 (de)
DK (1) DK1641434T3 (de)
ES (1) ES2319995T3 (de)
GB (1) GB0315632D0 (de)
NZ (1) NZ544718A (de)
PL (1) PL1641434T3 (de)
PT (1) PT1641434E (de)
WO (1) WO2005004838A1 (de)
ZA (1) ZA200600027B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0315632D0 (en) 2003-07-04 2003-08-13 West Pharm Serv Drug Res Ltd Pharmaceutical formulations
US20090136505A1 (en) * 2005-02-23 2009-05-28 Johanna Bentz Intranasal Administration of Active Agents to the Central Nervous System
GB2438834A (en) 2006-06-08 2007-12-12 Optinose As Intranasal protein administration
CA2657581A1 (en) * 2006-07-11 2008-01-17 Roy C. Levitt Rhinosinusitis prevention and therapy with proinflammatory cytokine inhibitors
US20080182819A1 (en) * 2007-01-29 2008-07-31 Act Iii Licensing, Llc Chitosan compositions and methods for using chitosan compositions in the treatment of health disorders
GB0812742D0 (en) 2008-07-11 2008-08-20 Critical Pharmaceuticals Ltd Process
WO2010056896A1 (en) 2008-11-12 2010-05-20 Synedgen, Inc. Chitosan derivatives to treat animals or optimize animal health
WO2013078396A2 (en) * 2011-11-23 2013-05-30 Durect Corporation Radiation-sterilized biodegradable drug delivery compositions
GB201319437D0 (en) * 2013-11-04 2013-12-18 Nanomerics Ltd Delivery of drugs
JP6564369B2 (ja) 2013-12-09 2019-08-21 デュレクト コーポレイション 薬学的活性剤複合体、ポリマー複合体、ならびにこれらを伴う組成物及び方法
US10111836B2 (en) 2015-02-01 2018-10-30 Orsenix Holdings Bv High surface-area lyophilized compositions comprising arsenic for oral administration in patients
CN112601541A (zh) * 2018-06-22 2021-04-02 比欧拉利克斯有限公司 口服给药的生物聚合物制剂

Family Cites Families (25)

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Publication number Priority date Publication date Assignee Title
US5690954A (en) * 1987-05-22 1997-11-25 Danbiosyst Uk Limited Enhanced uptake drug delivery system having microspheres containing an active drug and a bioavailability improving material
GB8904370D0 (en) 1989-02-25 1989-04-12 Cosmas Damian Ltd Liquid delivery compositions
JPH07118170A (ja) * 1993-10-19 1995-05-09 Dot:Kk 経鼻吸収薬物用キャリヤ、生理活性ペプチド組成物およびその製造法
US20010053359A1 (en) * 1994-07-26 2001-12-20 Peter Watts Drug delivery composition for the nasal administration of antiviral agents
GB9416884D0 (en) 1994-08-20 1994-10-12 Danbiosyst Uk Drug delivery compositions
GB9419979D0 (en) 1994-10-04 1994-11-16 Medeva Holdings Bv Vaccine compositions
SE9403905D0 (sv) * 1994-11-14 1994-11-14 Astra Ab New formulations
GB9522351D0 (en) 1995-11-01 1996-01-03 Medeva Holdings Bv Vaccine compositions
GB9525083D0 (en) * 1995-12-07 1996-02-07 Danbiosyst Uk Vaccine compositions
ES2205177T5 (es) 1996-02-27 2007-08-01 Teijin Limited Composicion en polvo para administracion nasal.
US5912014A (en) * 1996-03-15 1999-06-15 Unigene Laboratories, Inc. Oral salmon calcitonin pharmaceutical products
GB2330534B (en) 1996-07-10 2000-09-06 Danbiosyst Uk Gene therapy delivery system for targeting to endothelia
GB9700624D0 (en) * 1997-01-14 1997-03-05 Danbiosyst Uk Drug delivery composition
GB9707934D0 (en) 1997-04-18 1997-06-04 Danbiosyst Uk Improved delivery of drugs to mucosal surfaces
GB9713980D0 (en) 1997-07-03 1997-09-10 Danbiosyst Uk New conjugates
GB9725084D0 (en) 1997-11-28 1998-01-28 Medeva Europ Ltd Vaccine compositions
DE69930509T2 (de) * 1998-07-08 2006-11-30 Kirin-Amgen Inc., Wilmington Pulverförmiges präparat zur anwendung auf schleimhäuten welches ein polymeres arzneimittel enthält
SE9803239D0 (sv) 1998-09-24 1998-09-24 Diabact Ab Composition for the treatment of acute pain
GB9924797D0 (en) 1999-10-20 1999-12-22 West Pharm Serv Drug Res Ltd Compound
US20020013331A1 (en) 2000-06-26 2002-01-31 Williams Robert O. Methods and compositions for treating pain of the mucous membrane
PL207845B1 (pl) 2000-07-31 2011-02-28 Nycomed Danmark As Spray donosowy do dostarczania kompozycji farmaceutycznej zawierającej fentanyl i zastosowanie soli fentanylu do wytwarzania środka leczniczego
EP1458362A4 (de) * 2001-11-19 2006-01-18 Becton Dickinson Co Pharmazeutische zusammensetzungen in teilchenform
US7666876B2 (en) 2002-03-19 2010-02-23 Vernalis (R&D) Limited Buprenorphine formulations for intranasal delivery
GB0300531D0 (en) 2003-01-10 2003-02-12 West Pharm Serv Drug Res Ltd Pharmaceutical compositions
GB0315632D0 (en) 2003-07-04 2003-08-13 West Pharm Serv Drug Res Ltd Pharmaceutical formulations

Also Published As

Publication number Publication date
US7662403B2 (en) 2010-02-16
WO2005004838A8 (en) 2005-03-17
PL1641434T3 (pl) 2009-08-31
CA2531239C (en) 2011-05-24
PT1641434E (pt) 2009-03-19
DE602004018496D1 (de) 2009-01-29
NZ544718A (en) 2009-06-26
US20100021553A1 (en) 2010-01-28
CA2531239A1 (en) 2005-01-20
US8481070B2 (en) 2013-07-09
ZA200600027B (en) 2009-08-26
EP1641434A1 (de) 2006-04-05
AU2004255515B2 (en) 2009-04-30
AU2004255515A2 (en) 2005-01-20
EP1641434B1 (de) 2008-12-17
ES2319995T3 (es) 2009-05-18
DK1641434T3 (da) 2009-04-06
WO2005004838A1 (en) 2005-01-20
AU2004255515A1 (en) 2005-01-20
GB0315632D0 (en) 2003-08-13
US20060120973A1 (en) 2006-06-08

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