DE602004011348D1 - Indanderivate als muscarinrezeptoragonisten - Google Patents
Indanderivate als muscarinrezeptoragonistenInfo
- Publication number
- DE602004011348D1 DE602004011348D1 DE602004011348T DE602004011348T DE602004011348D1 DE 602004011348 D1 DE602004011348 D1 DE 602004011348D1 DE 602004011348 T DE602004011348 T DE 602004011348T DE 602004011348 T DE602004011348 T DE 602004011348T DE 602004011348 D1 DE602004011348 D1 DE 602004011348D1
- Authority
- DE
- Germany
- Prior art keywords
- indanderivates
- receptor agonists
- muscarin receptor
- muscarin
- agonists
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
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- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
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- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
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- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Communicable Diseases (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Child & Adolescent Psychology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Toxicology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48469603P | 2003-07-03 | 2003-07-03 | |
US484696P | 2003-07-03 | ||
PCT/US2004/019094 WO2005009941A1 (en) | 2003-07-03 | 2004-06-23 | Indane derivates as muscarinic receptor agonists |
Publications (2)
Publication Number | Publication Date |
---|---|
DE602004011348D1 true DE602004011348D1 (de) | 2008-03-06 |
DE602004011348T2 DE602004011348T2 (de) | 2009-01-08 |
Family
ID=34102660
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004011348T Active DE602004011348T2 (de) | 2003-07-03 | 2004-06-23 | Indanderivate als muscarinrezeptoragonisten |
Country Status (8)
Country | Link |
---|---|
US (1) | US7265246B2 (de) |
EP (1) | EP1644320B1 (de) |
JP (1) | JP2007520440A (de) |
AT (1) | ATE384039T1 (de) |
CA (1) | CA2529036A1 (de) |
DE (1) | DE602004011348T2 (de) |
ES (1) | ES2298819T3 (de) |
WO (1) | WO2005009941A1 (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1819846A (zh) * | 2004-05-21 | 2006-08-16 | 千寿制药株式会社 | 包含毒蕈碱性受体激动剂的经皮肤吸收的眼用制剂 |
US20090012101A1 (en) * | 2005-12-27 | 2009-01-08 | University Of Toledo | Mucarinic Agonists and Methods of Use Thereof |
JP2011520905A (ja) | 2008-05-15 | 2011-07-21 | ザ・ユニバーシティ・オブ・トレド | 向知性剤としてのムスカリンアゴニスト |
WO2010043721A1 (en) | 2008-10-17 | 2010-04-22 | Oryzon Genomics, S.A. | Oxidase inhibitors and their use |
US8993808B2 (en) | 2009-01-21 | 2015-03-31 | Oryzon Genomics, S.A. | Phenylcyclopropylamine derivatives and their medical use |
ES2882797T3 (es) | 2009-04-02 | 2021-12-02 | Merck Serono Sa | Inhibidores de dihidroorotato deshidrogenasa |
WO2010141690A2 (en) * | 2009-06-04 | 2010-12-09 | Dara Biosciences, Inc. | Indane analogs and use as pharmaceutical agents and process of making |
MX338041B (es) | 2009-09-25 | 2016-03-30 | Oryzon Genomics Sa | Inhibidores de demetilasa-1 especificos de lisina y su uso. |
US8946296B2 (en) | 2009-10-09 | 2015-02-03 | Oryzon Genomics S.A. | Substituted heteroaryl- and aryl-cyclopropylamine acetamides and their use |
WO2011106574A2 (en) | 2010-02-24 | 2011-09-01 | Oryzon Genomics, S.A. | Inhibitors for antiviral use |
US9186337B2 (en) | 2010-02-24 | 2015-11-17 | Oryzon Genomics S.A. | Lysine demethylase inhibitors for diseases and disorders associated with Hepadnaviridae |
ES2607081T3 (es) | 2010-04-19 | 2017-03-29 | Oryzon Genomics, S.A. | Inhibidores de desmetilasa específica de lisina-1 y su uso |
WO2012007500A2 (de) | 2010-07-15 | 2012-01-19 | Bayer Cropscience Ag | Neue heterocyclische verbindungen als schädlingsbekämpfungsmittel |
LT2598482T (lt) | 2010-07-29 | 2018-07-10 | Oryzon Genomics, S.A. | Demetilazės lsd1 inhibitoriai arilciklopropilamino pagrindu ir jų medicininis panaudojimas |
EP2598480B1 (de) | 2010-07-29 | 2019-04-24 | Oryzon Genomics, S.A. | Cyclopropylaminderivate als lsd1-hemmer |
WO2012045883A1 (en) | 2010-10-08 | 2012-04-12 | Oryzon Genomics S.A. | Cyclopropylamine inhibitors of oxidases |
WO2012072713A2 (en) | 2010-11-30 | 2012-06-07 | Oryzon Genomics, S.A. | Lysine demethylase inhibitors for diseases and disorders associated with flaviviridae |
WO2012107498A1 (en) | 2011-02-08 | 2012-08-16 | Oryzon Genomics S.A. | Lysine demethylase inhibitors for myeloproliferative disorders |
US9549928B2 (en) | 2011-04-29 | 2017-01-24 | The University Of Toledo | Muscarinic agonists as enhancers of cognitive flexibility |
BR112014009306B1 (pt) | 2011-10-20 | 2021-07-20 | Oryzon Genomics S.A. | Compostos de (hetero)aril ciclopropilamina como inibidores de lsd1 |
CA2849564C (en) | 2011-10-20 | 2020-10-20 | Oryzon Genomics, S.A. | (hetero)aryl cyclopropylamine compounds as lsd1 inhibitors |
WO2017070229A1 (en) | 2015-10-19 | 2017-04-27 | Board Of Regents, The University Of Texas System | Piperazinyl norbenzomorphan compounds and methods for using the same |
US10653681B2 (en) | 2016-03-16 | 2020-05-19 | Recurium Ip Holdings, Llc | Analgesic compounds |
WO2017190109A1 (en) * | 2016-04-29 | 2017-11-02 | Board Of Regents, The University Of Texas System | Sigma receptor binders |
CA3022432A1 (en) * | 2016-04-29 | 2017-11-02 | Board Of Regents, The University Of Texas System | Sigma receptor binders |
CN114736128A (zh) * | 2022-03-10 | 2022-07-12 | 青岛科技大学 | 一种制备邻氨基苯醚的方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0880558A1 (de) * | 1996-01-22 | 1998-12-02 | Eli Lilly And Company | Kombinatorisches verfahren zur herstellung von bibliotheken des substituierten indans |
AU8591898A (en) | 1997-07-22 | 1999-02-16 | Eli Lilly And Company | Pharmaceutical compounds |
TWI241190B (en) * | 2001-02-13 | 2005-10-11 | Aventis Pharma Gmbh | 4-Fluoro-N-indan-2-yl benzamide and its use as pharmaceutical |
CN1556788A (zh) * | 2001-09-21 | 2004-12-22 | 毒蕈碱受体激动剂 |
-
2004
- 2004-06-23 AT AT04776610T patent/ATE384039T1/de not_active IP Right Cessation
- 2004-06-23 CA CA002529036A patent/CA2529036A1/en not_active Abandoned
- 2004-06-23 US US10/560,757 patent/US7265246B2/en not_active Expired - Fee Related
- 2004-06-23 DE DE602004011348T patent/DE602004011348T2/de active Active
- 2004-06-23 ES ES04776610T patent/ES2298819T3/es active Active
- 2004-06-23 JP JP2006518649A patent/JP2007520440A/ja active Pending
- 2004-06-23 EP EP04776610A patent/EP1644320B1/de not_active Not-in-force
- 2004-06-23 WO PCT/US2004/019094 patent/WO2005009941A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
CA2529036A1 (en) | 2005-02-03 |
US7265246B2 (en) | 2007-09-04 |
EP1644320A1 (de) | 2006-04-12 |
ES2298819T3 (es) | 2008-05-16 |
ATE384039T1 (de) | 2008-02-15 |
US20070060587A1 (en) | 2007-03-15 |
WO2005009941A1 (en) | 2005-02-03 |
EP1644320B1 (de) | 2008-01-16 |
DE602004011348T2 (de) | 2009-01-08 |
JP2007520440A (ja) | 2007-07-26 |
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Legal Events
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8364 | No opposition during term of opposition | ||
8328 | Change in the person/name/address of the agent |
Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336 |
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8328 | Change in the person/name/address of the agent |
Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN |