DE602004010307D1 - Verwendung von polysulfatiertem alginat in zellmatrix - Google Patents
Verwendung von polysulfatiertem alginat in zellmatrixInfo
- Publication number
- DE602004010307D1 DE602004010307D1 DE602004010307T DE602004010307T DE602004010307D1 DE 602004010307 D1 DE602004010307 D1 DE 602004010307D1 DE 602004010307 T DE602004010307 T DE 602004010307T DE 602004010307 T DE602004010307 T DE 602004010307T DE 602004010307 D1 DE602004010307 D1 DE 602004010307D1
- Authority
- DE
- Germany
- Prior art keywords
- polysulpated
- alginate
- cell matrix
- matrix
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
- A61L27/3852—Cartilage, e.g. meniscus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0655—Chondrocytes; Cartilage
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/10—Materials or treatment for tissue regeneration for reconstruction of tendons or ligaments
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
- C12N2533/74—Alginate
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Dermatology (AREA)
- Biotechnology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Developmental Biology & Embryology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US52649203P | 2003-12-02 | 2003-12-02 | |
US526492P | 2003-12-02 | ||
PCT/BE2004/000171 WO2005054446A2 (en) | 2003-12-02 | 2004-12-02 | Use of polysulphated alginate in cellular matrices |
Publications (2)
Publication Number | Publication Date |
---|---|
DE602004010307D1 true DE602004010307D1 (de) | 2008-01-03 |
DE602004010307T2 DE602004010307T2 (de) | 2008-09-25 |
Family
ID=34652456
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004010307T Active DE602004010307T2 (de) | 2003-12-02 | 2004-12-02 | Verwendung von polysulfatiertem alginat in zellmatrix |
Country Status (5)
Country | Link |
---|---|
US (1) | US7988962B2 (de) |
EP (1) | EP1711595B1 (de) |
DE (1) | DE602004010307T2 (de) |
ES (1) | ES2297516T3 (de) |
WO (1) | WO2005054446A2 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2251289B1 (es) * | 2004-02-27 | 2007-07-01 | Bioiberica, S.A. | Nuevo uso terapeutico de un grupo de polisacaridos sulfatados. |
ES2298052B1 (es) | 2006-08-03 | 2009-09-28 | Bioiberica S.A. | Procedimiento para la proliferacion de celulas. |
BRPI0906972B1 (pt) | 2008-01-30 | 2021-09-08 | Histogen, Inc | Métodos para produção de composições de matriz extracelular e para produção de uma proteína wnt e de um fator de crescimento endotelial vascular |
CA2767600C (en) | 2009-07-10 | 2022-05-31 | Histogen, Inc. | Conditioned medium and extracellular matrix compositions from cells cultured under hypoxic conditions |
US9352003B1 (en) | 2010-05-14 | 2016-05-31 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
US8883210B1 (en) | 2010-05-14 | 2014-11-11 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
US10130736B1 (en) | 2010-05-14 | 2018-11-20 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
US8834928B1 (en) | 2011-05-16 | 2014-09-16 | Musculoskeletal Transplant Foundation | Tissue-derived tissugenic implants, and methods of fabricating and using same |
WO2014072035A1 (en) | 2012-11-07 | 2014-05-15 | Eth Zurich | Sulfated alginate hydrogels for cell culture and therapy |
US10531957B2 (en) | 2015-05-21 | 2020-01-14 | Musculoskeletal Transplant Foundation | Modified demineralized cortical bone fibers |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5705178A (en) | 1991-05-31 | 1998-01-06 | Gliatech, Inc. | Methods and compositions based on inhibition of cell invasion and fibrosis by anionic polymers |
US5605938A (en) | 1991-05-31 | 1997-02-25 | Gliatech, Inc. | Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate |
GB2317182B (en) | 1996-09-11 | 2000-11-01 | Johnson & Johnson Medical | Sulfated polysaccharides and uses thereof in medical treatment |
DE10026699A1 (de) * | 2000-05-30 | 2001-12-06 | Basf Ag | Formulierung auf Heparin-, Glycosaminoglycan- oder Heparinoidbasis und Verwendung der Formulierung sowie der Formulierungsgrundlage |
FR2811572B1 (fr) | 2000-07-17 | 2003-04-18 | Adir | Utilisation de cyclodextrines polysulfatees pour le traitement de l'arthrose |
-
2004
- 2004-12-02 DE DE602004010307T patent/DE602004010307T2/de active Active
- 2004-12-02 US US10/595,821 patent/US7988962B2/en not_active Expired - Fee Related
- 2004-12-02 WO PCT/BE2004/000171 patent/WO2005054446A2/en active IP Right Grant
- 2004-12-02 ES ES04801137T patent/ES2297516T3/es active Active
- 2004-12-02 EP EP04801137A patent/EP1711595B1/de not_active Not-in-force
Also Published As
Publication number | Publication date |
---|---|
US20070128173A1 (en) | 2007-06-07 |
US7988962B2 (en) | 2011-08-02 |
ES2297516T3 (es) | 2008-05-01 |
EP1711595A2 (de) | 2006-10-18 |
DE602004010307T2 (de) | 2008-09-25 |
WO2005054446A2 (en) | 2005-06-16 |
EP1711595B1 (de) | 2007-11-21 |
WO2005054446A3 (en) | 2005-07-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE391718T1 (de) | Phenylacetamide und ihre verwendung als glukokinase-modulatoren | |
EP1487857A4 (de) | Gene von endothelzellen aus lymphe und blut | |
IS7992A (is) | Dýralaus frumuræktunar aðferð | |
DE50313510D1 (de) | Zellkultureinsatz | |
DK2341147T3 (da) | Præprimitive stribe- og mesendodermceller | |
DE602004022088D1 (de) | Zellkultivierungskolben | |
ATE511507T1 (de) | Piperidinylcarbonylpyrrolidine und deren verwendung als melanocortinagonisten | |
DE602004028934D1 (de) | Benzoä4,5üthienoä2,3-düpyrimidin-4-one und ihre therapeutische verwendung | |
DE60325967D1 (de) | Stimulierung von hämatopoiese bei ex vivo aktivierten immunzellen | |
DE602004010307D1 (de) | Verwendung von polysulfatiertem alginat in zellmatrix | |
ATE362469T1 (de) | 2,7-disubstituierteindole und ihre verwendung als 5-ht6 modulatoren | |
NO20053825D0 (no) | Thienopyridazinoner og deres anvendelse ved modulering av autoimmune sykdommer. | |
DE60322926D1 (de) | Photopolymerisierbare zusammensetzung und verwendung davon | |
DE50307817D1 (de) | Wellenleiter in porösen substraten | |
DE502004008433D1 (de) | Wägezelle | |
DE50300769D1 (de) | Erdalkalialuminosilicatglas und verwendung | |
ATE413396T1 (de) | Pyrazindicarbonsäureamide und ihre verwendung | |
DE50303362D1 (de) | Kraftaufnehmer | |
ATE277023T1 (de) | Indanderivate und ihre verwendung als zelladhäsionsinihibitoren | |
NO20033082L (no) | Enkeltcelleproteinmateriale | |
DE502004011753D1 (de) | Verwendung von pit-emulsionen in enzymatischen reaktionen | |
DE50304051D1 (de) | Verwendung von kunststofffolien als dielektrikum in kondensatoren | |
GB0316742D0 (en) | Electrophoretic gels and their manufacture | |
DK1565562T3 (da) | Sekvensspecifik dna-rekombination i eukaryotiske celler | |
FI20031458A (fi) | Kantopakkaus ja pakkauksen kantorakenne |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee | ||
8370 | Indication of lapse of patent is to be deleted |