DE602004002491D1 - Ein keramischer Überzug mit einem biologischen Aktivstoff und Verfahren zur Herstellung - Google Patents
Ein keramischer Überzug mit einem biologischen Aktivstoff und Verfahren zur HerstellungInfo
- Publication number
- DE602004002491D1 DE602004002491D1 DE602004002491T DE602004002491T DE602004002491D1 DE 602004002491 D1 DE602004002491 D1 DE 602004002491D1 DE 602004002491 T DE602004002491 T DE 602004002491T DE 602004002491 T DE602004002491 T DE 602004002491T DE 602004002491 D1 DE602004002491 D1 DE 602004002491D1
- Authority
- DE
- Germany
- Prior art keywords
- preparation
- ceramic coating
- biological active
- biological agent
- implantable article
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000005524 ceramic coating Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 239000003124 biologic agent Substances 0.000 abstract 2
- 239000000758 substrate Substances 0.000 abstract 2
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 abstract 1
- 230000000975 bioactive effect Effects 0.000 abstract 1
- 229910001424 calcium ion Inorganic materials 0.000 abstract 1
- 239000000919 ceramic Substances 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/32—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US355827 | 2003-01-31 | ||
US10/355,827 US7087086B2 (en) | 2003-01-31 | 2003-01-31 | Biological agent-containing ceramic coating and method |
Publications (2)
Publication Number | Publication Date |
---|---|
DE602004002491D1 true DE602004002491D1 (de) | 2006-11-09 |
DE602004002491T2 DE602004002491T2 (de) | 2007-05-03 |
Family
ID=32655588
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004002491T Expired - Lifetime DE602004002491T2 (de) | 2003-01-31 | 2004-01-22 | Ein keramischer Überzug mit einem biologischen Aktivstoff und Verfahren zur Herstellung |
Country Status (6)
Country | Link |
---|---|
US (1) | US7087086B2 (de) |
EP (1) | EP1442755B1 (de) |
JP (1) | JP2004230174A (de) |
AT (1) | ATE340595T1 (de) |
AU (1) | AU2004200224B2 (de) |
DE (1) | DE602004002491T2 (de) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100036502A1 (en) * | 2008-08-07 | 2010-02-11 | Exogenesis Corporation | Medical device for bone implant and method for producing such device |
JP4699902B2 (ja) * | 2003-10-27 | 2011-06-15 | Hoya株式会社 | リン酸カルシウムセラミックス多孔体及びその製造方法 |
US20050196519A1 (en) * | 2004-03-08 | 2005-09-08 | Depuy Products, Inc. | Apparatus for producing a biomimetic coating on a medical implant |
DE102004021244A1 (de) * | 2004-04-30 | 2005-11-24 | Immundiagnostik Ag | Bioaktive Werkstoffe und Verfahren zur Verbesserung der Einwachseigenschaften von Knochenimplantaten |
SE527610C2 (sv) * | 2004-06-15 | 2006-04-25 | Promimic Ab | Förfarande för framställning av syntetiskt, kristallint kalciumfosfat i nanostorlek |
US20080241353A1 (en) * | 2004-08-10 | 2008-10-02 | Yekimed Ag | Biomimetic Process For Coating Substrates With A Biomimetic Solution Containing A Bioactive Substance And Use Of Said Process And Substrates In Bone, Connective Tissue-, Fat Tissue-And Muscle Tissue Engineering |
US20060093646A1 (en) * | 2004-10-28 | 2006-05-04 | Cima Michael J | Orthopedic and dental implant devices providing controlled drug delivery |
US8329202B2 (en) * | 2004-11-12 | 2012-12-11 | Depuy Products, Inc. | System and method for attaching soft tissue to an implant |
CA2532388A1 (en) * | 2005-01-07 | 2006-07-07 | Inframat Corporation | Coated medical devices and methods of making and using |
JP2006275667A (ja) * | 2005-03-28 | 2006-10-12 | Iwate Univ | 生体用金属に対する血清タンパク質複合体形成の評価方法 |
US20060257358A1 (en) * | 2005-05-13 | 2006-11-16 | Depuy Products, Inc. | Suspension of calcium phosphate particulates for local delivery of therapeutic agents |
US7531190B2 (en) * | 2005-05-25 | 2009-05-12 | Biomet Manufacturing Corp. | Porous ceramic structure containing biologics |
US20070016163A1 (en) * | 2005-06-28 | 2007-01-18 | Microchips, Inc. | Medical and dental implant devices for controlled drug delivery |
US9763788B2 (en) | 2005-09-09 | 2017-09-19 | Board Of Trustees Of The University Of Arkansas | Bone regeneration using biodegradable polymeric nanocomposite materials and applications of the same |
US8936805B2 (en) | 2005-09-09 | 2015-01-20 | Board Of Trustees Of The University Of Arkansas | Bone regeneration using biodegradable polymeric nanocomposite materials and applications of the same |
WO2007030752A2 (en) * | 2005-09-09 | 2007-03-15 | University Of Arkansas At Little Rock | System and method for tissue generation and bone regeneration |
WO2007044229A2 (en) * | 2005-09-28 | 2007-04-19 | Calcitec, Inc. | Surface treatments for calcium phosphate-based implants |
CA2629600C (en) | 2005-11-14 | 2011-11-01 | Biomet 3I, Inc. | Deposition of discrete nanoparticles on an implant surface |
WO2008079152A2 (en) * | 2006-01-04 | 2008-07-03 | University Of Connecticut | Ceramic coating and method of preparation thereof |
US8187660B2 (en) * | 2006-01-05 | 2012-05-29 | Howmedica Osteonics Corp. | Method for fabricating a medical implant component and such component |
US20070158446A1 (en) * | 2006-01-05 | 2007-07-12 | Howmedica Osteonics Corp. | Method for fabricating a medical implant component and such component |
US7836847B2 (en) * | 2006-02-17 | 2010-11-23 | Howmedica Osteonics Corp. | Multi-station rotation system for use in spray operations |
US7981479B2 (en) * | 2006-02-17 | 2011-07-19 | Howmedica Osteonics Corp. | Multi-station rotation system for use in spray operations |
US20080069854A1 (en) * | 2006-08-02 | 2008-03-20 | Inframat Corporation | Medical devices and methods of making and using |
CN101588826A (zh) * | 2006-08-02 | 2009-11-25 | 英孚拉玛特公司 | 腔支撑装置及其制造及使用方法 |
WO2008051555A2 (en) | 2006-10-24 | 2008-05-02 | Biomet 3I, Llc. | Deposition of discrete nanoparticles on a nanostructured surface of an implant |
CA2689675A1 (en) * | 2007-02-07 | 2008-08-14 | Mcgill University | Bioceramic implants having bioactive substance |
EP2211763A4 (de) * | 2007-11-06 | 2013-02-13 | Univ Connecticut | Keramik-/strukturproteinverbundstoffe und verfahren zu ihrer herstellung |
US9149563B2 (en) * | 2007-11-06 | 2015-10-06 | The University Of Connecticut | Calcium phosphate/structural protein composites and method of preparation thereof |
JP5248848B2 (ja) * | 2007-12-11 | 2013-07-31 | 山八歯材工業株式会社 | インプラントの製造方法及び人工歯根の製造方法 |
ES2545781T3 (es) | 2008-01-28 | 2015-09-15 | Biomet 3I, Llc | Implante superficial con mayor hidrofilia |
US9011965B2 (en) * | 2008-02-29 | 2015-04-21 | Smith & Nephew, Inc. | Gradient coating for biomedical applications |
AU2009222172B2 (en) * | 2008-02-29 | 2015-06-18 | Smith & Nephew, Inc. | Medical implant with coating and coating method |
CA2734254C (en) | 2008-08-13 | 2018-06-05 | Smed-Ta/Td, Llc | Orthopaedic screws |
US9700431B2 (en) | 2008-08-13 | 2017-07-11 | Smed-Ta/Td, Llc | Orthopaedic implant with porous structural member |
WO2010019781A1 (en) | 2008-08-13 | 2010-02-18 | Smed-Ta/Td, Llc | Drug delivery implants |
US9616205B2 (en) | 2008-08-13 | 2017-04-11 | Smed-Ta/Td, Llc | Drug delivery implants |
US10842645B2 (en) | 2008-08-13 | 2020-11-24 | Smed-Ta/Td, Llc | Orthopaedic implant with porous structural member |
JP5687622B2 (ja) | 2008-08-29 | 2015-03-18 | スメド−ティーエイ/ティーディー・エルエルシー | 整形外科インプラント |
EP2453934B1 (de) | 2009-06-18 | 2013-06-12 | Teknimed | Verfahren zur oberflächenaktivierung bei porösen biomaterialien |
EP2269663B1 (de) | 2009-07-03 | 2018-03-07 | Armbruster Biotechnology GmbH | Knochenimplantat und bioverbundstoff |
US8641418B2 (en) | 2010-03-29 | 2014-02-04 | Biomet 3I, Llc | Titanium nano-scale etching on an implant surface |
ES2373896B1 (es) * | 2010-07-30 | 2013-03-12 | Universidad Complutense De Madrid | Biomaterial con osteostatina para regeneración ósea e ingeniería tisular. |
WO2012068239A1 (en) * | 2010-11-17 | 2012-05-24 | Zimmer, Inc. | Ceramic monoblock implants with osseointegration fixation surfaces |
US8551525B2 (en) | 2010-12-23 | 2013-10-08 | Biostructures, Llc | Bone graft materials and methods |
ES2671740T3 (es) | 2012-03-20 | 2018-06-08 | Biomet 3I, Llc | Superficie de tratamiento para una superficie de implante |
WO2013142763A1 (en) | 2012-03-22 | 2013-09-26 | University Of Connecticut | Biomimetic scaffold for bone regeneration |
US20140141047A1 (en) * | 2012-11-19 | 2014-05-22 | Wisconsin Alumni Research Foundation | Selection of platelet rich plasma components via mineral binding |
EP3231453B1 (de) | 2016-04-14 | 2019-12-25 | Immundiagnostik AG | Bone-sialopreotein(bsp)-funktionalisierte knochenersatzkörper |
JP6967294B2 (ja) * | 2017-02-02 | 2021-11-17 | 国立研究開発法人産業技術総合研究所 | セラミックス結晶の被覆層を有する複合体とその製造方法 |
US10537658B2 (en) | 2017-03-28 | 2020-01-21 | DePuy Synthes Products, Inc. | Orthopedic implant having a crystalline gallium-containing hydroxyapatite coating and methods for making the same |
US10537661B2 (en) | 2017-03-28 | 2020-01-21 | DePuy Synthes Products, Inc. | Orthopedic implant having a crystalline calcium phosphate coating and methods for making the same |
EP3632881A4 (de) * | 2017-05-22 | 2021-03-03 | Hangzhou Erran Technology Co. Ltd. | Biologisch aktive nanooxidkeramikschicht |
EP3919022A4 (de) * | 2019-01-31 | 2022-03-16 | Cell-Medicine, Inc. | Medizinisches instrument mit anorganischem salz-protein-komposit |
CN112869897B (zh) * | 2021-01-14 | 2022-01-25 | 南京医科大学附属口腔医院 | 一种氧化锆种植体表面处理方法 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
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US4596574A (en) * | 1984-05-14 | 1986-06-24 | The Regents Of The University Of California | Biodegradable porous ceramic delivery system for bone morphogenetic protein |
US5258029A (en) * | 1988-09-29 | 1993-11-02 | Collagen Corporation | Method for improving implant fixation |
JPH0629126B2 (ja) * | 1989-03-29 | 1994-04-20 | 京都大学長 | 生体活性水酸アパタイト膜のコーティング法 |
JP3198125B2 (ja) * | 1991-06-18 | 2001-08-13 | 株式会社アドバンス | インプラントの製造方法 |
US5947893A (en) * | 1994-04-27 | 1999-09-07 | Board Of Regents, The University Of Texas System | Method of making a porous prothesis with biodegradable coatings |
US6180606B1 (en) * | 1994-09-28 | 2001-01-30 | Gensci Orthobiologics, Inc. | Compositions with enhanced osteogenic potential, methods for making the same and uses thereof |
IT1288038B1 (it) * | 1996-04-30 | 1998-09-10 | Flametal S P A | Procedimento per la preparazione di rivestimenti di idrossiapatite |
US6143948A (en) * | 1996-05-10 | 2000-11-07 | Isotis B.V. | Device for incorporation and release of biologically active agents |
GB2316940A (en) * | 1996-08-30 | 1998-03-11 | Queen Mary & Westfield College | Silicon-substituted hydroxyapatite |
US6129928A (en) * | 1997-09-05 | 2000-10-10 | Icet, Inc. | Biomimetic calcium phosphate implant coatings and methods for making the same |
US6214049B1 (en) | 1999-01-14 | 2001-04-10 | Comfort Biomedical, Inc. | Method and apparatus for augmentating osteointegration of prosthetic implant devices |
US6139585A (en) * | 1998-03-11 | 2000-10-31 | Depuy Orthopaedics, Inc. | Bioactive ceramic coating and method |
AU772751B2 (en) * | 1998-09-15 | 2004-05-06 | Isotis N.V. | Method for coating medical implants |
JP2003521351A (ja) * | 2000-02-04 | 2003-07-15 | イソティス エヌ.ブイ. | 蛋白質性コーティング |
JP2003535620A (ja) * | 2000-02-18 | 2003-12-02 | リジェネレーション テクノロジーズ インク. | 増殖因子および他の添加物を注入した移植用組織 |
GB0010411D0 (en) | 2000-04-28 | 2000-06-14 | Abonetics Ltd | A process for the preparation of carbonated biomedical materials |
US6461382B1 (en) * | 2000-09-22 | 2002-10-08 | Edwards Lifesciences Corporation | Flexible heart valve having moveable commissures |
-
2003
- 2003-01-31 US US10/355,827 patent/US7087086B2/en active Active
-
2004
- 2004-01-21 AU AU2004200224A patent/AU2004200224B2/en not_active Ceased
- 2004-01-22 DE DE602004002491T patent/DE602004002491T2/de not_active Expired - Lifetime
- 2004-01-22 AT AT04250323T patent/ATE340595T1/de not_active IP Right Cessation
- 2004-01-22 EP EP04250323A patent/EP1442755B1/de not_active Expired - Lifetime
- 2004-01-30 JP JP2004023905A patent/JP2004230174A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ATE340595T1 (de) | 2006-10-15 |
US20040153165A1 (en) | 2004-08-05 |
EP1442755A1 (de) | 2004-08-04 |
US7087086B2 (en) | 2006-08-08 |
JP2004230174A (ja) | 2004-08-19 |
AU2004200224A1 (en) | 2004-08-19 |
DE602004002491T2 (de) | 2007-05-03 |
EP1442755B1 (de) | 2006-09-27 |
AU2004200224B2 (en) | 2010-03-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |