ATE340595T1 - Ein keramischer überzug mit einem biologischen aktivstoff und verfahren zur herstellung - Google Patents

Ein keramischer überzug mit einem biologischen aktivstoff und verfahren zur herstellung

Info

Publication number
ATE340595T1
ATE340595T1 AT04250323T AT04250323T ATE340595T1 AT E340595 T1 ATE340595 T1 AT E340595T1 AT 04250323 T AT04250323 T AT 04250323T AT 04250323 T AT04250323 T AT 04250323T AT E340595 T1 ATE340595 T1 AT E340595T1
Authority
AT
Austria
Prior art keywords
ceramic coating
producing
biological active
biological agent
implantable article
Prior art date
Application number
AT04250323T
Other languages
English (en)
Inventor
Panjian Li
Hai Bo Wen
Elizabeth A Hippensteel
Original Assignee
Depuy Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Depuy Products Inc filed Critical Depuy Products Inc
Application granted granted Critical
Publication of ATE340595T1 publication Critical patent/ATE340595T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/30Inorganic materials
    • A61L27/32Phosphorus-containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406Antibiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412Tissue-regenerating or healing or proliferative agents
    • A61L2300/414Growth factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606Coatings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
AT04250323T 2003-01-31 2004-01-22 Ein keramischer überzug mit einem biologischen aktivstoff und verfahren zur herstellung ATE340595T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/355,827 US7087086B2 (en) 2003-01-31 2003-01-31 Biological agent-containing ceramic coating and method

Publications (1)

Publication Number Publication Date
ATE340595T1 true ATE340595T1 (de) 2006-10-15

Family

ID=32655588

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04250323T ATE340595T1 (de) 2003-01-31 2004-01-22 Ein keramischer überzug mit einem biologischen aktivstoff und verfahren zur herstellung

Country Status (6)

Country Link
US (1) US7087086B2 (de)
EP (1) EP1442755B1 (de)
JP (1) JP2004230174A (de)
AT (1) ATE340595T1 (de)
AU (1) AU2004200224B2 (de)
DE (1) DE602004002491T2 (de)

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US20050196519A1 (en) * 2004-03-08 2005-09-08 Depuy Products, Inc. Apparatus for producing a biomimetic coating on a medical implant
DE102004021244A1 (de) * 2004-04-30 2005-11-24 Immundiagnostik Ag Bioaktive Werkstoffe und Verfahren zur Verbesserung der Einwachseigenschaften von Knochenimplantaten
SE527610C2 (sv) * 2004-06-15 2006-04-25 Promimic Ab Förfarande för framställning av syntetiskt, kristallint kalciumfosfat i nanostorlek
WO2006016807A2 (en) * 2004-08-10 2006-02-16 Yekimed Ag Biomimetic process for coating substrates
EP1812090A1 (de) * 2004-10-28 2007-08-01 Microchips, Inc. Orthopädische und dentale implantate mit kontrollierter arzneimittelfreisetzung
US8329202B2 (en) * 2004-11-12 2012-12-11 Depuy Products, Inc. System and method for attaching soft tissue to an implant
US20060184251A1 (en) * 2005-01-07 2006-08-17 Zongtao Zhang Coated medical devices and methods of making and using
JP2006275667A (ja) * 2005-03-28 2006-10-12 Iwate Univ 生体用金属に対する血清タンパク質複合体形成の評価方法
US20060257358A1 (en) * 2005-05-13 2006-11-16 Depuy Products, Inc. Suspension of calcium phosphate particulates for local delivery of therapeutic agents
US7531190B2 (en) * 2005-05-25 2009-05-12 Biomet Manufacturing Corp. Porous ceramic structure containing biologics
WO2007001624A2 (en) * 2005-06-28 2007-01-04 Microchips, Inc. Medical and dental implant devices for controlled drug delivery
EP1931401A2 (de) * 2005-09-09 2008-06-18 University of Arkansas at Little Rock System und verfahren für die gewebegeneration und knochenregeneration
US8936805B2 (en) 2005-09-09 2015-01-20 Board Of Trustees Of The University Of Arkansas Bone regeneration using biodegradable polymeric nanocomposite materials and applications of the same
US9763788B2 (en) 2005-09-09 2017-09-19 Board Of Trustees Of The University Of Arkansas Bone regeneration using biodegradable polymeric nanocomposite materials and applications of the same
WO2007044229A2 (en) * 2005-09-28 2007-04-19 Calcitec, Inc. Surface treatments for calcium phosphate-based implants
EP1962914B1 (de) 2005-11-14 2019-02-27 Biomet 3i, LLC Abscheidung von diskreten nanoteilchen auf einer implantatoberfläche
WO2008079152A2 (en) * 2006-01-04 2008-07-03 University Of Connecticut Ceramic coating and method of preparation thereof
US20070158446A1 (en) * 2006-01-05 2007-07-12 Howmedica Osteonics Corp. Method for fabricating a medical implant component and such component
US8187660B2 (en) * 2006-01-05 2012-05-29 Howmedica Osteonics Corp. Method for fabricating a medical implant component and such component
US7981479B2 (en) * 2006-02-17 2011-07-19 Howmedica Osteonics Corp. Multi-station rotation system for use in spray operations
US7836847B2 (en) * 2006-02-17 2010-11-23 Howmedica Osteonics Corp. Multi-station rotation system for use in spray operations
CN101588826A (zh) * 2006-08-02 2009-11-25 英孚拉玛特公司 腔支撑装置及其制造及使用方法
US20080069854A1 (en) * 2006-08-02 2008-03-20 Inframat Corporation Medical devices and methods of making and using
EP2079401B1 (de) 2006-10-24 2019-05-22 Biomet 3i, LLC Ablagerung diskreter nanopartikel auf einer nanostrukturierten oberfläche eines implantats
CA2689675A1 (en) * 2007-02-07 2008-08-14 Mcgill University Bioceramic implants having bioactive substance
CA2704652A1 (en) * 2007-11-06 2009-05-14 Mei Wei Ceramic/structural protein composites and method of preparation thereof
US9149563B2 (en) * 2007-11-06 2015-10-06 The University Of Connecticut Calcium phosphate/structural protein composites and method of preparation thereof
JP5248848B2 (ja) * 2007-12-11 2013-07-31 山八歯材工業株式会社 インプラントの製造方法及び人工歯根の製造方法
JP5806466B2 (ja) 2008-01-28 2015-11-10 バイオメット・3アイ・エルエルシー 親水性を向上させたインプラント表面
US8821911B2 (en) * 2008-02-29 2014-09-02 Smith & Nephew, Inc. Coating and coating method
ES2603961T3 (es) * 2008-02-29 2017-03-02 Smith & Nephew, Inc. Recubrimiento de gradiente para aplicaciones biomédicas
JP5878369B2 (ja) * 2008-08-07 2016-03-08 エクソジェネシス コーポレーション 骨インプラントのための医療機器およびその機器の製造方法
EP2339973B1 (de) 2008-08-13 2017-10-18 Smed-Ta/Td, Llc Wirkstofffreisetzungsimplantate
US9358056B2 (en) 2008-08-13 2016-06-07 Smed-Ta/Td, Llc Orthopaedic implant
US9616205B2 (en) 2008-08-13 2017-04-11 Smed-Ta/Td, Llc Drug delivery implants
US9700431B2 (en) 2008-08-13 2017-07-11 Smed-Ta/Td, Llc Orthopaedic implant with porous structural member
US10842645B2 (en) 2008-08-13 2020-11-24 Smed-Ta/Td, Llc Orthopaedic implant with porous structural member
US20100042213A1 (en) 2008-08-13 2010-02-18 Nebosky Paul S Drug delivery implants
MX2011013416A (es) 2009-06-18 2012-07-23 Univ Toulouse Metodo para activar la superficie de biomateriales porosos.
EP2269663B1 (de) 2009-07-03 2018-03-07 Armbruster Biotechnology GmbH Knochenimplantat und bioverbundstoff
US8641418B2 (en) 2010-03-29 2014-02-04 Biomet 3I, Llc Titanium nano-scale etching on an implant surface
ES2373896B1 (es) * 2010-07-30 2013-03-12 Universidad Complutense De Madrid Biomaterial con osteostatina para regeneración ósea e ingeniería tisular.
WO2012068239A1 (en) * 2010-11-17 2012-05-24 Zimmer, Inc. Ceramic monoblock implants with osseointegration fixation surfaces
US8551525B2 (en) 2010-12-23 2013-10-08 Biostructures, Llc Bone graft materials and methods
ES2671740T3 (es) 2012-03-20 2018-06-08 Biomet 3I, Llc Superficie de tratamiento para una superficie de implante
WO2013142763A1 (en) 2012-03-22 2013-09-26 University Of Connecticut Biomimetic scaffold for bone regeneration
US20140141047A1 (en) * 2012-11-19 2014-05-22 Wisconsin Alumni Research Foundation Selection of platelet rich plasma components via mineral binding
EP3231453B1 (de) 2016-04-14 2019-12-25 Immundiagnostik AG Bone-sialopreotein(bsp)-funktionalisierte knochenersatzkörper
EP3578595A4 (de) * 2017-02-02 2020-12-16 National Institute Of Advanced Industrial Science And Technology Verbundkörper mit einer beschichtungsschicht aus keramikkristall und verfahren zur herstellung davon
US10537658B2 (en) 2017-03-28 2020-01-21 DePuy Synthes Products, Inc. Orthopedic implant having a crystalline gallium-containing hydroxyapatite coating and methods for making the same
US10537661B2 (en) 2017-03-28 2020-01-21 DePuy Synthes Products, Inc. Orthopedic implant having a crystalline calcium phosphate coating and methods for making the same
WO2018214808A1 (zh) * 2017-05-22 2018-11-29 杭州而然科技有限公司 一种具有生物活性的纳米氧化物陶瓷薄膜
WO2020158833A1 (ja) * 2019-01-31 2020-08-06 セルメディシン株式会社 無機塩類タンパク複合医療機器
CN112869897B (zh) * 2021-01-14 2022-01-25 南京医科大学附属口腔医院 一种氧化锆种植体表面处理方法

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Also Published As

Publication number Publication date
US7087086B2 (en) 2006-08-08
DE602004002491T2 (de) 2007-05-03
US20040153165A1 (en) 2004-08-05
DE602004002491D1 (de) 2006-11-09
EP1442755A1 (de) 2004-08-04
AU2004200224B2 (en) 2010-03-25
EP1442755B1 (de) 2006-09-27
AU2004200224A1 (en) 2004-08-19
JP2004230174A (ja) 2004-08-19

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