DE602004002405D1 - Kontrollierte medikamentfreigabe zusammensetzung mit in vivo mechanikstresswiderstand - Google Patents
Kontrollierte medikamentfreigabe zusammensetzung mit in vivo mechanikstresswiderstandInfo
- Publication number
- DE602004002405D1 DE602004002405D1 DE602004002405T DE602004002405T DE602004002405D1 DE 602004002405 D1 DE602004002405 D1 DE 602004002405D1 DE 602004002405 T DE602004002405 T DE 602004002405T DE 602004002405 T DE602004002405 T DE 602004002405T DE 602004002405 D1 DE602004002405 D1 DE 602004002405D1
- Authority
- DE
- Germany
- Prior art keywords
- drug
- release
- vivo
- matrix
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229940079593 drug Drugs 0.000 title abstract 7
- 239000003814 drug Substances 0.000 title abstract 7
- 239000000203 mixture Substances 0.000 title abstract 4
- 239000011159 matrix material Substances 0.000 abstract 4
- 238000001727 in vivo Methods 0.000 abstract 3
- 238000013270 controlled release Methods 0.000 abstract 2
- 230000008855 peristalsis Effects 0.000 abstract 2
- 229920002678 cellulose Polymers 0.000 abstract 1
- 239000001913 cellulose Substances 0.000 abstract 1
- 238000007907 direct compression Methods 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 125000005908 glyceryl ester group Chemical group 0.000 abstract 1
- 238000005469 granulation Methods 0.000 abstract 1
- 230000003179 granulation Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 239000012730 sustained-release form Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IE20030366 | 2003-05-14 | ||
IE20030366 | 2003-05-14 | ||
EP04741578A EP1628642B2 (de) | 2003-05-14 | 2004-05-14 | Kontrollierte medikamentfreigabe zusammensetzung mit in vivo mechanikstresswiderstand |
PCT/EP2004/050814 WO2004100932A1 (en) | 2003-05-14 | 2004-05-14 | Controlled drug release composition resistant to in vivo mechanic stress |
Publications (3)
Publication Number | Publication Date |
---|---|
DE602004002405D1 true DE602004002405D1 (de) | 2006-10-26 |
DE602004002405T2 DE602004002405T2 (de) | 2007-09-06 |
DE602004002405T3 DE602004002405T3 (de) | 2013-06-20 |
Family
ID=33446353
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004002405T Expired - Lifetime DE602004002405T3 (de) | 2003-05-14 | 2004-05-14 | Kontrollierte medikamentfreigabe zusammensetzung mit in vivo mechanikstresswiderstand |
Country Status (7)
Country | Link |
---|---|
US (1) | US20070009596A1 (de) |
EP (1) | EP1628642B2 (de) |
AT (1) | ATE339192T1 (de) |
DE (1) | DE602004002405T3 (de) |
ES (1) | ES2273271T5 (de) |
PL (1) | PL1628642T3 (de) |
WO (1) | WO2004100932A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL1847258T5 (pl) † | 2006-04-13 | 2013-06-28 | Acino Pharma Ag | Częściowe glicerydy jako środki poślizgowe dla kompozycji farmaceutycznych zawierających pochodne tieno[3,2-c]pirydyny |
CN101639471A (zh) * | 2009-08-21 | 2010-02-03 | 天津中医药大学 | 一种用于评价药物固体制剂溶出/吸收过程的装置 |
WO2011090724A2 (en) * | 2009-12-29 | 2011-07-28 | Impax Laboratories, Inc. | Gastroretentive solid oral dosage forms with lipid-based low-density excipient |
WO2011146300A1 (en) * | 2010-05-17 | 2011-11-24 | Merck Sharp & Dohme Corp. | Novel prolylcarboxypeptidase inhibitors |
CN105651822A (zh) * | 2014-11-14 | 2016-06-08 | 湘潭大学 | 固体制剂活性物溶出性质的测试方法和测试装置 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4832957A (en) * | 1987-12-11 | 1989-05-23 | Merck & Co., Inc. | Controlled release combination of carbidopa/levodopa |
ZA889189B (en) * | 1986-06-16 | 1989-08-30 | Merck & Co Inc | Controlled release combination of carbidopa/levodopa |
US4983400A (en) * | 1986-06-16 | 1991-01-08 | Merck & Co., Inc. | Controlled release combination of carbidopa/levodopa |
FR2656525A1 (fr) * | 1989-12-29 | 1991-07-05 | Delalande Sa | Formes d'administration de medicament a liberation controlee et leur procede de fabrication. |
GB9619074D0 (en) * | 1996-09-12 | 1996-10-23 | Smithkline Beecham Plc | Composition |
FR2775597B1 (fr) * | 1998-03-04 | 2001-04-20 | Gattefosse Ets Sa | Pellet administrable par voie orale apte a ameliorer la biodisponibilite de la substance active, procede de fabrication |
AR030557A1 (es) † | 2000-04-14 | 2003-08-27 | Jagotec Ag | Una tableta en multicapa de liberacion controlada y metodo de tratamiento |
US6287599B1 (en) * | 2000-12-20 | 2001-09-11 | Shire Laboratories, Inc. | Sustained release pharmaceutical dosage forms with minimized pH dependent dissolution profiles |
US6531153B2 (en) * | 2001-05-29 | 2003-03-11 | Drugtech Corporation | Composition with sustained release of levodopa and carbidopa |
GB0125088D0 (en) † | 2001-10-18 | 2001-12-12 | Smithkline Beecham Cork Ltd | New use |
-
2004
- 2004-05-14 EP EP04741578A patent/EP1628642B2/de not_active Expired - Lifetime
- 2004-05-14 US US10/556,734 patent/US20070009596A1/en not_active Abandoned
- 2004-05-14 AT AT04741578T patent/ATE339192T1/de not_active IP Right Cessation
- 2004-05-14 ES ES04741578T patent/ES2273271T5/es not_active Expired - Lifetime
- 2004-05-14 WO PCT/EP2004/050814 patent/WO2004100932A1/en active IP Right Grant
- 2004-05-14 PL PL04741578T patent/PL1628642T3/pl unknown
- 2004-05-14 DE DE602004002405T patent/DE602004002405T3/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ES2273271T3 (es) | 2007-05-01 |
EP1628642A1 (de) | 2006-03-01 |
PL1628642T3 (pl) | 2007-01-31 |
DE602004002405T2 (de) | 2007-09-06 |
ES2273271T5 (es) | 2013-05-21 |
WO2004100932A1 (en) | 2004-11-25 |
EP1628642B1 (de) | 2006-09-13 |
ATE339192T1 (de) | 2006-10-15 |
US20070009596A1 (en) | 2007-01-11 |
DE602004002405T3 (de) | 2013-06-20 |
EP1628642B2 (de) | 2013-01-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent |