DE60143704D1 - Verfahren zur herstellung einer medizinischen festen dispersion - Google Patents

Verfahren zur herstellung einer medizinischen festen dispersion

Info

Publication number
DE60143704D1
DE60143704D1 DE60143704T DE60143704T DE60143704D1 DE 60143704 D1 DE60143704 D1 DE 60143704D1 DE 60143704 T DE60143704 T DE 60143704T DE 60143704 T DE60143704 T DE 60143704T DE 60143704 D1 DE60143704 D1 DE 60143704D1
Authority
DE
Germany
Prior art keywords
producing
solid dispersion
medical solid
medical
dispersion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60143704T
Other languages
English (en)
Inventor
Tomio Nakano
Toshinori Tanaka
Shogo Izumi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Shinyaku Co Ltd
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Application granted granted Critical
Publication of DE60143704D1 publication Critical patent/DE60143704D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60143704T 2000-09-25 2001-09-25 Verfahren zur herstellung einer medizinischen festen dispersion Expired - Lifetime DE60143704D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000289760 2000-09-25
PCT/JP2001/008288 WO2002024168A1 (fr) 2000-09-25 2001-09-25 Procede de production d'une dispersion solide medicinale

Publications (1)

Publication Number Publication Date
DE60143704D1 true DE60143704D1 (de) 2011-02-03

Family

ID=18773098

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60143704T Expired - Lifetime DE60143704D1 (de) 2000-09-25 2001-09-25 Verfahren zur herstellung einer medizinischen festen dispersion

Country Status (5)

Country Link
US (1) US20040013736A1 (de)
EP (1) EP1323416B1 (de)
JP (1) JP4997683B2 (de)
DE (1) DE60143704D1 (de)
WO (1) WO2002024168A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
CN101091695B (zh) * 2003-02-03 2011-01-19 诺瓦提斯公司 药物制剂
US8377952B2 (en) * 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
WO2006118210A1 (ja) * 2005-04-28 2006-11-09 Eisai R & D Management Co., Ltd. ジヒドロピリジン系化合物の分解を防止する方法
EP1912625B1 (de) * 2005-08-08 2016-04-13 AbbVie Deutschland GmbH & Co KG Itraconazol-zusammensetzungen mit verbesserter bioverfügbarkeit
US20090028938A1 (en) 2005-08-08 2009-01-29 Abbott Gmbh & Co. Kg Dosage forms with improved bioavailability
JP6150518B2 (ja) 2012-12-27 2017-06-21 花王株式会社 ポリフェノール組成物の製造方法
US20200397700A1 (en) * 2018-02-21 2020-12-24 Nippon Shinyaku Co., Ltd. Granular composition, production method for granular composition, and dissolution property improvement method for granular composition
CN114652690B (zh) * 2022-03-31 2023-03-21 山东新时代药业有限公司 一种用于肠梗阻的甲氧氯普胺新制剂及其工艺

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4301146A (en) * 1980-07-29 1981-11-17 G. D. Searle & Co. Stabilization of 16-oxygenated prostanoic acid derivatives
AU1537292A (en) * 1991-04-16 1992-11-17 Nippon Shinyaku Co. Ltd. Method of manufacturing solid dispersion
FR2702968B1 (fr) * 1993-03-23 1995-06-23 Lafon Labor Procédé de préparation de particules renfermant un ingrédient actif par extrusion et lyophilisation .
US5843347A (en) * 1993-03-23 1998-12-01 Laboratoire L. Lafon Extrusion and freeze-drying method for preparing particles containing an active ingredient
DE4316537A1 (de) * 1993-05-18 1994-11-24 Basf Ag Zubereitungen in Form fester Lösungen
JPH07291854A (ja) * 1994-04-26 1995-11-07 Tanabe Seiyaku Co Ltd 溶解性の改善された医薬品製剤
TW487582B (en) * 1995-08-11 2002-05-21 Nissan Chemical Ind Ltd Method for converting sparingly water-soluble medical substance to amorphous state
HN1998000115A (es) * 1997-08-21 1999-06-02 Warner Lambert Co Formas de dosificación farmacéuticas sólidas
DE19913692A1 (de) * 1999-03-25 2000-09-28 Basf Ag Mechanisch stabile pharmazeutische Darreichungsformen, enthaltend flüssige oder halbfeste oberflächenaktive Substanzen

Also Published As

Publication number Publication date
EP1323416A1 (de) 2003-07-02
EP1323416B1 (de) 2010-12-22
WO2002024168A1 (fr) 2002-03-28
EP1323416A4 (de) 2005-09-21
US20040013736A1 (en) 2004-01-22
JPWO2002024168A1 (ja) 2004-01-29
JP4997683B2 (ja) 2012-08-08

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