DE60141520D1 - 5-asa-derivate mit entzündungshemmender und antibiotischer wirkung und verfahren zur behandlung von krankheiten mit diesen derivaten - Google Patents

5-asa-derivate mit entzündungshemmender und antibiotischer wirkung und verfahren zur behandlung von krankheiten mit diesen derivaten

Info

Publication number
DE60141520D1
DE60141520D1 DE60141520T DE60141520T DE60141520D1 DE 60141520 D1 DE60141520 D1 DE 60141520D1 DE 60141520 T DE60141520 T DE 60141520T DE 60141520 T DE60141520 T DE 60141520T DE 60141520 D1 DE60141520 D1 DE 60141520D1
Authority
DE
Germany
Prior art keywords
diseases
derivatives
treatment
inflammatory
asa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60141520T
Other languages
German (de)
English (en)
Inventor
Nnochiri N Ekwuribe
Elizabeth Malson
Jennifer Riggs-Sauthier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biocon Ltd
Original Assignee
Biocon Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocon Ltd filed Critical Biocon Ltd
Application granted granted Critical
Publication of DE60141520D1 publication Critical patent/DE60141520D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/51—Y being a hydrogen or a carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60141520T 2000-08-29 2001-08-28 5-asa-derivate mit entzündungshemmender und antibiotischer wirkung und verfahren zur behandlung von krankheiten mit diesen derivaten Expired - Lifetime DE60141520D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22868200P 2000-08-29 2000-08-29
PCT/US2001/041910 WO2002018330A1 (en) 2000-08-29 2001-08-28 5-asa derivatives having anti-inflammatory and antibiotic activity and methods of treating diseases therewith

Publications (1)

Publication Number Publication Date
DE60141520D1 true DE60141520D1 (de) 2010-04-22

Family

ID=22858177

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60141520T Expired - Lifetime DE60141520D1 (de) 2000-08-29 2001-08-28 5-asa-derivate mit entzündungshemmender und antibiotischer wirkung und verfahren zur behandlung von krankheiten mit diesen derivaten

Country Status (10)

Country Link
US (1) US6458776B1 (https=)
EP (1) EP1313699B1 (https=)
JP (1) JP5112595B2 (https=)
AT (1) ATE460394T1 (https=)
AU (1) AU2001285489A1 (https=)
CA (1) CA2421114C (https=)
DE (1) DE60141520D1 (https=)
IL (2) IL154537A0 (https=)
MX (1) MXPA03001786A (https=)
WO (1) WO2002018330A1 (https=)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1313697T3 (da) 2000-08-29 2006-04-10 Nobex Corp Immunregulatoriske forbindelser, derivater deraf samt anvendelse deraf
US8048924B2 (en) 2001-08-29 2011-11-01 Biocon Limited Methods and compositions employing 4-aminophenylacetic acid compounds
CA2496547A1 (en) * 2002-08-29 2004-03-11 University Of Southampton Use of apoptosis inducing agents in the preparation of a medicament for the treatment of liver diseases
WO2004078172A2 (en) * 2003-03-06 2004-09-16 Yissum Research Development Company Of The Hebrew University Of Jerusalem Sod mimic multifunctional compounds for treating inflammatory bowel disease
SE523093C2 (sv) * 2003-03-25 2004-03-30 Sven Kindblom Stötdämpare för höjdreglering
ES2398237T3 (es) 2003-07-23 2013-03-14 Novartis Ag Uso de calcitonina en osteoartritis
JP2007520495A (ja) 2004-02-06 2007-07-26 ボロディー トーマス ユリウス 下痢型過敏性腸症候群におけるアミノサリチル酸の使用法
US20080306029A1 (en) * 2004-05-28 2008-12-11 Salix Pharmaceuticals, Inc. Prevention, Treatment, and Amelioration of Radiation Induced Enteritis
DK1773767T3 (en) 2004-07-07 2016-03-21 Biocon Ltd Synthesis of azo bound in immune regulatory relations
US20060270635A1 (en) * 2005-05-27 2006-11-30 Wallace John L Derivatives of 4- or 5-aminosalicylic acid
US8541398B2 (en) * 2005-05-27 2013-09-24 Antibe Therapeutics Inc. Hydrogen sulfide derivatives of non-steroidal anti-inflammatory drugs
US7666907B2 (en) * 2005-05-27 2010-02-23 Antibe Therapeutics Inc. Salts of trimebutine and N-desmethyl trimebutine
WO2006125293A1 (en) * 2005-05-27 2006-11-30 Antibe Therapeutics Inc. Derivatives of 4- or 5-aminosalicylic acid
US7498355B2 (en) * 2005-05-27 2009-03-03 Antibe Therapeutics Inc. Derivatives of 4- or 5-aminosalicylic acid
US7741359B2 (en) * 2005-05-27 2010-06-22 Antibe Therapeutics Inc. Hydrogen sulfide derivatives of non-steroidal anti-inflammatory drugs
EP2529729A1 (en) * 2005-08-24 2012-12-05 Salix Pharmaceuticals, Inc. Balsalazide formulations and manufacture thereof
US8921344B2 (en) * 2006-11-03 2014-12-30 Salix Pharmaceuticals, Inc. Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
US7452872B2 (en) 2005-08-24 2008-11-18 Salix Pharmaceuticals, Inc. Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
AU2006318815B2 (en) 2005-11-17 2010-08-19 Novartis Ag Pharmaceutical composition
WO2007103448A2 (en) * 2006-03-09 2007-09-13 Salix Pharmaceuticals, Inc. Rifaximin anti-rectal dysfunction preparation
US7271253B1 (en) * 2006-08-10 2007-09-18 Apotex Pharmachem Inc. Safe process for the preparation of balsalazide
JPWO2008114831A1 (ja) * 2007-03-20 2010-07-08 国立大学法人 岡山大学 スルホンアミド基を有する抗菌剤
US20090098088A1 (en) * 2007-10-10 2009-04-16 The Procter & Gamble Company Methods And Kits For The Treatment Of Diverticular Conditions
MX2010011995A (es) * 2008-05-01 2010-12-02 Procter & Gamble Metodos y estuches para el tratamiento de condiciones y trastornos inflamatorios del intestino.
CN105348184B (zh) * 2015-11-26 2020-12-29 苏州统华药品有限公司 一种柳氮磺吡啶的制备方法
US11744859B2 (en) 2017-07-07 2023-09-05 Epicentrx, Inc. Compositions and methods for parenteral administration of therapeutic agents

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2270676A (en) * 1936-08-20 1942-01-20 Winthrop Chem Co Inc Sulphonic acid amide compound
US2396145A (en) * 1940-12-14 1946-03-05 Pharmscia Ab Heterocyclic sulphonamido azo compounds
BE791889A (fr) * 1971-11-26 1973-05-24 Pharmacia Ab Nouveaux derives de la pyridine
JPS5353449A (en) * 1976-10-22 1978-05-15 Sofuia Kk Picture type pachinko game machine
US4412992A (en) * 1980-07-21 1983-11-01 Biorex Laboratories Limited 2-Hydroxy-5-phenylazobenzoic acid derivatives and method of treating ulcerative colitis therewith
SU1011126A1 (ru) * 1981-07-14 1983-04-15 Всесоюзный научно-исследовательский и испытательный институт медицинской техники Средство дл лечени сахарного диабета
CS142691A3 (en) * 1991-05-15 1992-11-18 Vyzk Ustav Farm Biochem Sp Process for preparing 5-//4-/(4',6'-dimethyl-2-pyrimidinyl)sulfamoyl/phenyl/azo/-acetylsalicylic acid
SE9700934D0 (sv) * 1997-03-14 1997-03-14 Astra Ab New formulation

Also Published As

Publication number Publication date
IL154537A0 (en) 2003-09-17
IL154537A (en) 2013-07-31
JP5112595B2 (ja) 2013-01-09
ATE460394T1 (de) 2010-03-15
US20020111334A1 (en) 2002-08-15
CA2421114C (en) 2010-12-07
CA2421114A1 (en) 2002-03-07
AU2001285489A1 (en) 2002-03-13
JP2004507521A (ja) 2004-03-11
WO2002018330A1 (en) 2002-03-07
US6458776B1 (en) 2002-10-01
MXPA03001786A (es) 2003-06-04
EP1313699B1 (en) 2010-03-10
EP1313699A1 (en) 2003-05-28

Similar Documents

Publication Publication Date Title
DE60141520D1 (de) 5-asa-derivate mit entzündungshemmender und antibiotischer wirkung und verfahren zur behandlung von krankheiten mit diesen derivaten
EA200200873A1 (ru) Новые пиперазиновые производные
EA200400944A1 (ru) Замещенные производные тетрациклина, фармацевтическая композиция и способ лечения субъекта с их использованием
EA200501098A1 (ru) Антибактериальные агенты
BR9509212A (pt) Composto composição farmacêutica método de inibição de prostaglandina H sintase em um mamífero método de tratamento de uma doença inflamatória em um mamífero e método de tratamento de pirese em um mamífero
ATE312823T1 (de) Verfahren zur herstellung heteroarylsubstituierter ureaverbindungen
DE69912581D1 (de) Biarylessigsäure-derivate und ihre verwendung als cox-2 inhibitoren
EA200500814A1 (ru) Производные пирролопиримидина
ATE306261T1 (de) Antithrombosemittel
EA200100412A1 (ru) Замещенные 3-цианохинолины в качестве ингибиторов протеинтирозинкиназ
DK1485359T3 (da) Natriumkanalblokkere
ATE202337T1 (de) Cyclopropylalkansäurederivate
UY28280A1 (es) 2- hidroxi - 3- diaminoalcanos de benzamida
DE60021873D1 (de) Zubereitung zur prophylaxe oder behandlung der demenz-erkrankung enthaltend ein hydroxyzimtsäurederivat oder einen extrakt einer pflanze der gattung angelica, der diese säure enthält.
WO2002018324A3 (en) Immunoregulatory compounds, derivatives thereof and their use
EA200600621A1 (ru) Производные тетрагидронафталина, способ их получения и их применение в качестве противовоспалительных средств
EA200000804A1 (ru) Мета-азациклические соединения аминобензойной кислоты и их производные, являющиеся ингибиторами интегрина
PE55298A1 (es) Derivados de pirrolopirrolona
YU94103A (sh) Novi derivati sulfonske kiseline
CY1109085T1 (el) Νεα αλατα
EE04564B1 (et) Bifenlamidiini derivaadid, eelravim, vere koagulatsiooniinhibiitor ning proflaktiline ja terapeutiline toimeaine tromboosi v?i emboolia vastu
EA200000741A1 (ru) Новые производные дигидроксигексановой кислоты
EA200200108A1 (ru) Производные стрептограминов, способ их получения и композиции на их основе
EA200200489A1 (ru) Новые соединения бензотиадиазина, способ их получения и содержащие их фармацевтические композиции
TNSN97092A1 (ar) مثبطات انزيم بروتيني فلزي وتركيبات صيدلانية تحتوي على تلك المثبتطات واستخدامها الصيدلاني وطرق ومركبات وسيطة مفيدة لتحضير التركيبات المذكورة.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition