DE60140892D1 - Hemmung oder umkehrung der hautalterung durch actin-sequestrierende peptide - Google Patents
Hemmung oder umkehrung der hautalterung durch actin-sequestrierende peptideInfo
- Publication number
- DE60140892D1 DE60140892D1 DE60140892T DE60140892T DE60140892D1 DE 60140892 D1 DE60140892 D1 DE 60140892D1 DE 60140892 T DE60140892 T DE 60140892T DE 60140892 T DE60140892 T DE 60140892T DE 60140892 D1 DE60140892 D1 DE 60140892D1
- Authority
- DE
- Germany
- Prior art keywords
- actin
- sequestrating
- reversal
- peptides
- inhibition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 230000009759 skin aging Effects 0.000 title abstract 2
- 230000005764 inhibitory process Effects 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- UGPMCIBIHRSCBV-XNBOLLIBSA-N Thymosin beta 4 Chemical compound N([C@@H](CC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(O)=O)C(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(C)=O UGPMCIBIHRSCBV-XNBOLLIBSA-N 0.000 abstract 3
- 102100035000 Thymosin beta-4 Human genes 0.000 abstract 3
- 108010079996 thymosin beta(4) Proteins 0.000 abstract 3
- 102000001708 Protein Isoforms Human genes 0.000 abstract 1
- 108010029485 Protein Isoforms Proteins 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57581—Thymosin; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Birds (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24490100P | 2000-11-02 | 2000-11-02 | |
| PCT/US2001/042900 WO2002036143A1 (en) | 2000-11-02 | 2001-11-02 | Inhibition or reversal of skin aging by actin-sequestering peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60140892D1 true DE60140892D1 (de) | 2010-02-04 |
Family
ID=22924553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60140892T Expired - Lifetime DE60140892D1 (de) | 2000-11-02 | 2001-11-02 | Hemmung oder umkehrung der hautalterung durch actin-sequestrierende peptide |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1335743B1 (enExample) |
| JP (2) | JP4224297B2 (enExample) |
| AT (1) | ATE452647T1 (enExample) |
| AU (2) | AU1351302A (enExample) |
| CA (1) | CA2426200C (enExample) |
| DE (1) | DE60140892D1 (enExample) |
| DK (1) | DK1335743T3 (enExample) |
| ES (1) | ES2338633T3 (enExample) |
| PT (1) | PT1335743E (enExample) |
| WO (1) | WO2002036143A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2311485A1 (en) | 1998-07-30 | 2011-04-20 | The Government of the United States of America, as represented by the Secretary of Health and Human Services | Thymosin beta 4 promotes wound repair |
| US6821524B2 (en) * | 2002-06-03 | 2004-11-23 | Jan Marini Skin Research, Inc. | Cosmetic skin care compositions |
| WO2005087805A1 (en) * | 2004-03-05 | 2005-09-22 | Regenerx Biopharmaceuticals, Inc. | Treating or preventing extracellular matrix build-up |
| MX2008001084A (es) | 2005-07-26 | 2008-03-11 | Regenerx Biopharmaceuticals | Composiciones para el tratamiento o prevencion del deterioro, lesion o dano de tejido debido a insuficiencia cardiaca congestiva. |
| EP2260106A4 (en) * | 2008-03-17 | 2011-04-20 | Regenerx Biopharmaceuticals | IMPROVED BETATHYMOSINFRAGMENTS |
| US9808654B2 (en) | 2013-02-11 | 2017-11-07 | Jan Marini Skin Research | Post procedure skin care gel and methods of use thereof |
| KR102265430B1 (ko) * | 2019-08-20 | 2021-06-15 | 주식회사 케어젠 | 피부 상태 개선 활성을 갖는 펩타이드 및 이의 용도 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9806632D0 (en) | 1998-03-28 | 1998-05-27 | Stevenson Robert | Peptide factor |
| EP2311485A1 (en) | 1998-07-30 | 2011-04-20 | The Government of the United States of America, as represented by the Secretary of Health and Human Services | Thymosin beta 4 promotes wound repair |
-
2001
- 2001-11-02 AT AT01981902T patent/ATE452647T1/de active
- 2001-11-02 AU AU1351302A patent/AU1351302A/xx active Pending
- 2001-11-02 CA CA2426200A patent/CA2426200C/en not_active Expired - Fee Related
- 2001-11-02 EP EP01981902A patent/EP1335743B1/en not_active Expired - Lifetime
- 2001-11-02 JP JP2002538954A patent/JP4224297B2/ja not_active Expired - Fee Related
- 2001-11-02 PT PT01981902T patent/PT1335743E/pt unknown
- 2001-11-02 AU AU2002213513A patent/AU2002213513B2/en not_active Ceased
- 2001-11-02 DK DK01981902.8T patent/DK1335743T3/da active
- 2001-11-02 WO PCT/US2001/042900 patent/WO2002036143A1/en not_active Ceased
- 2001-11-02 ES ES01981902T patent/ES2338633T3/es not_active Expired - Lifetime
- 2001-11-02 DE DE60140892T patent/DE60140892D1/de not_active Expired - Lifetime
-
2008
- 2008-10-03 JP JP2008258792A patent/JP2009046502A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2426200A1 (en) | 2002-05-10 |
| JP2004527463A (ja) | 2004-09-09 |
| JP4224297B2 (ja) | 2009-02-12 |
| JP2009046502A (ja) | 2009-03-05 |
| AU2002213513B2 (en) | 2006-05-25 |
| CA2426200C (en) | 2014-08-19 |
| EP1335743A1 (en) | 2003-08-20 |
| WO2002036143A1 (en) | 2002-05-10 |
| PT1335743E (pt) | 2010-03-29 |
| AU1351302A (en) | 2002-05-15 |
| ES2338633T3 (es) | 2010-05-11 |
| EP1335743A4 (en) | 2004-09-15 |
| EP1335743B1 (en) | 2009-12-23 |
| ATE452647T1 (de) | 2010-01-15 |
| DK1335743T3 (da) | 2010-04-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |