DE60137534D1 - Calciumkanalantagonisten vom n-typ zur behandlung von schmerzen - Google Patents

Calciumkanalantagonisten vom n-typ zur behandlung von schmerzen

Info

Publication number
DE60137534D1
DE60137534D1 DE60137534T DE60137534T DE60137534D1 DE 60137534 D1 DE60137534 D1 DE 60137534D1 DE 60137534 T DE60137534 T DE 60137534T DE 60137534 T DE60137534 T DE 60137534T DE 60137534 D1 DE60137534 D1 DE 60137534D1
Authority
DE
Germany
Prior art keywords
pain
treatment
type
calcium channel
channel antagonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60137534T
Other languages
English (en)
Inventor
Marc Chapdelaine
Lucius Kemp
John Mccauley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of DE60137534D1 publication Critical patent/DE60137534D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • C07D215/42Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE60137534T 2000-11-06 2001-10-31 Calciumkanalantagonisten vom n-typ zur behandlung von schmerzen Expired - Fee Related DE60137534D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0004056A SE0004056D0 (sv) 2000-11-06 2000-11-06 N-type calcium channel antagonists for the treatment of pain
PCT/SE2001/002391 WO2002036569A1 (en) 2000-11-06 2001-10-31 N-type calcium channel antagonists for the treatment of pain

Publications (1)

Publication Number Publication Date
DE60137534D1 true DE60137534D1 (de) 2009-03-12

Family

ID=20281716

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60137534T Expired - Fee Related DE60137534D1 (de) 2000-11-06 2001-10-31 Calciumkanalantagonisten vom n-typ zur behandlung von schmerzen

Country Status (9)

Country Link
US (1) US6841680B2 (de)
EP (1) EP1339690B1 (de)
JP (1) JP2004513118A (de)
AT (1) ATE421502T1 (de)
AU (1) AU2002212897A1 (de)
DE (1) DE60137534D1 (de)
ES (1) ES2319259T3 (de)
SE (1) SE0004056D0 (de)
WO (1) WO2002036569A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2862301B1 (fr) * 2003-11-17 2007-12-21 Aventis Pharma Sa Nouveau procede de preparation de quinoleines 3-fluorees
US20080300262A1 (en) * 2005-04-08 2008-12-04 Snutch Terrance P Combination Therapy for Relief of Pain
EP2019676A2 (de) * 2006-05-11 2009-02-04 Neuromed Pharmaceuticals, Ltd. Verfahren zur erhöhung der bioverfügbarkeit von benzhydrylpiperazinhaltigen verbindungen
BR112013010333A2 (pt) * 2010-10-29 2017-07-25 Clino Ltd sonda de imageamento de tau
MX2013010306A (es) 2011-03-08 2013-12-09 Zalicus Pharmaceuticals Ltd Formulaciones de dispersion solida y metodos de uso de las mismas.
US8409560B2 (en) 2011-03-08 2013-04-02 Zalicus Pharmaceuticals Ltd. Solid dispersion formulations and methods of use thereof
DE102016125645A1 (de) * 2016-12-23 2018-06-28 Forschungszentrum Jülich GmbH D-enantiomere Peptide zur Therapie von chronischem und neuropathischem Schmerz

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5506235A (en) * 1991-08-02 1996-04-09 Pfizer Inc. Quinoline derivatives as immunostimulants

Also Published As

Publication number Publication date
US20040053965A1 (en) 2004-03-18
EP1339690A1 (de) 2003-09-03
SE0004056D0 (sv) 2000-11-06
AU2002212897A1 (en) 2002-05-15
JP2004513118A (ja) 2004-04-30
ES2319259T3 (es) 2009-05-06
EP1339690B1 (de) 2009-01-21
ATE421502T1 (de) 2009-02-15
US6841680B2 (en) 2005-01-11
WO2002036569A1 (en) 2002-05-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee