DE60134557D1 - Neue carbonylreduktase, deren gen und verfahren zu dessen verwendung - Google Patents

Neue carbonylreduktase, deren gen und verfahren zu dessen verwendung

Info

Publication number
DE60134557D1
DE60134557D1 DE60134557T DE60134557T DE60134557D1 DE 60134557 D1 DE60134557 D1 DE 60134557D1 DE 60134557 T DE60134557 T DE 60134557T DE 60134557 T DE60134557 T DE 60134557T DE 60134557 D1 DE60134557 D1 DE 60134557D1
Authority
DE
Germany
Prior art keywords
benzyl
polypeptide
pyrrolidinol
amino acid
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60134557T
Other languages
English (en)
Inventor
Noriyuki Kizaki
Yoshihiko Yasohara
Junzo Hasegawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaneka Corp
Original Assignee
Kaneka Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaneka Corp filed Critical Kaneka Corp
Application granted granted Critical
Publication of DE60134557D1 publication Critical patent/DE60134557D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
DE60134557T 2000-08-01 2001-08-01 Neue carbonylreduktase, deren gen und verfahren zu dessen verwendung Expired - Lifetime DE60134557D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000232756 2000-08-01
PCT/JP2001/006619 WO2002010399A1 (fr) 2000-08-01 2001-08-01 Nouvelle carbonyl reductase, son gene et son procede d'utilisation

Publications (1)

Publication Number Publication Date
DE60134557D1 true DE60134557D1 (de) 2008-08-07

Family

ID=18725384

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60134557T Expired - Lifetime DE60134557D1 (de) 2000-08-01 2001-08-01 Neue carbonylreduktase, deren gen und verfahren zu dessen verwendung

Country Status (10)

Country Link
US (1) US7033808B2 (de)
EP (1) EP1306438B1 (de)
JP (1) JP4880859B2 (de)
KR (1) KR20020056894A (de)
AT (1) ATE399208T1 (de)
AU (1) AU2001278683A1 (de)
CA (1) CA2384625A1 (de)
DE (1) DE60134557D1 (de)
ES (1) ES2309082T3 (de)
WO (1) WO2002010399A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7666659B2 (en) * 2002-12-06 2010-02-23 Kaneka Corporation Process for producing optically active 3-hydroxypropionic ester derivative
JP4884996B2 (ja) * 2006-10-03 2012-02-29 国立大学法人 奈良先端科学技術大学院大学 新規な（ｓ）−ｎ−ベンジル−３−ピロリジノール脱水素酵素、その製造方法、及びこれを利用したアルコールの製造方法
JP5603076B2 (ja) * 2007-09-26 2014-10-08 株式会社カネカ 新規グルコース脱水素酵素
TWI468516B (zh) 2007-12-27 2015-01-11 Otsuka Pharma Co Ltd 與雌馬酚（ｅｑｕｏｌ）合成相關之酵素
US10000557B2 (en) * 2012-12-19 2018-06-19 Dnae Group Holdings Limited Methods for raising antibodies

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4096331A (en) * 1976-12-28 1978-06-20 A. H. Robins Company, Incorporated 1-Substituted-3-aminoethoxypyrrolidines
FI83517C (fi) * 1985-01-24 1991-07-25 Yamanouchi Pharma Co Ltd Foerfarande foer framstaellning av hoegervridande optisk isomer av (+-)-2,6-dimetyl-4-(m-nitrofenyl)-1,4 -dihydropyridin-3,5-dikarboxylsyra-3-(1-bensylpyrrolidin-3-yl) ester -5-metylester (ym-09730) av a-diastereomer.
JPH06141876A (ja) * 1992-11-10 1994-05-24 Kyowa Hakko Kogyo Co Ltd 光学活性なｎ−ベンジル−３−ピロリジノールの製造法
JP3703928B2 (ja) * 1996-11-26 2005-10-05 株式会社カネカ 光学活性ｎ−ベンジル−３−ピロリジノールの製造方法
JPH10150998A (ja) * 1996-11-26 1998-06-09 Kanegafuchi Chem Ind Co Ltd Ｎ−ベンジル−３−ピロリジノールの製造方法

Also Published As

Publication number Publication date
ES2309082T3 (es) 2008-12-16
JP4880859B2 (ja) 2012-02-22
EP1306438B1 (de) 2008-06-25
KR20020056894A (ko) 2002-07-10
ATE399208T1 (de) 2008-07-15
AU2001278683A1 (en) 2002-02-13
WO2002010399A1 (fr) 2002-02-07
CA2384625A1 (en) 2002-02-07
US7033808B2 (en) 2006-04-25
EP1306438A4 (de) 2005-03-02
EP1306438A1 (de) 2003-05-02
US20030186412A1 (en) 2003-10-02

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Legal Events

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