DE60131498D1 - VIRUS-HüLLENVEKTOR FüR GENTRANSFER - Google Patents

VIRUS-HüLLENVEKTOR FüR GENTRANSFER

Info

Publication number
DE60131498D1
DE60131498D1 DE60131498T DE60131498T DE60131498D1 DE 60131498 D1 DE60131498 D1 DE 60131498D1 DE 60131498 T DE60131498 T DE 60131498T DE 60131498 T DE60131498 T DE 60131498T DE 60131498 D1 DE60131498 D1 DE 60131498D1
Authority
DE
Germany
Prior art keywords
gentransfer
cover vector
virus cover
virus
vector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60131498T
Other languages
English (en)
Other versions
DE60131498T8 (de
DE60131498T2 (de
Inventor
Yasufumi Kaneda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anges Inc
Original Assignee
Anges MG Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anges MG Inc filed Critical Anges MG Inc
Publication of DE60131498D1 publication Critical patent/DE60131498D1/de
Application granted granted Critical
Publication of DE60131498T2 publication Critical patent/DE60131498T2/de
Publication of DE60131498T8 publication Critical patent/DE60131498T8/de
Active legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16611Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16661Methods of inactivation or attenuation
    • C12N2710/16663Methods of inactivation or attenuation by chemical treatment
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18811Sendai virus
    • C12N2760/18823Virus like particles [VLP]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18811Sendai virus
    • C12N2760/18861Methods of inactivation or attenuation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18811Sendai virus
    • C12N2760/18861Methods of inactivation or attenuation
    • C12N2760/18863Methods of inactivation or attenuation by chemical treatment
DE60131498T 2000-02-02 2001-02-02 VIRUSHÜLLENVEKTOR FüR DIE GENÜBERTRAGUNG Active DE60131498T8 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000025596 2000-02-02
JP2000025596 2000-02-02
PCT/JP2001/000782 WO2001057204A1 (fr) 2000-02-02 2001-02-02 Vecteur d'enveloppe virale pour transfert de gene

Publications (3)

Publication Number Publication Date
DE60131498D1 true DE60131498D1 (de) 2008-01-03
DE60131498T2 DE60131498T2 (de) 2008-10-02
DE60131498T8 DE60131498T8 (de) 2009-01-29

Family

ID=18551433

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60131498T Active DE60131498T8 (de) 2000-02-02 2001-02-02 VIRUSHÜLLENVEKTOR FüR DIE GENÜBERTRAGUNG

Country Status (10)

Country Link
US (3) US6913923B2 (de)
EP (1) EP1170363B1 (de)
KR (2) KR100847385B1 (de)
CN (3) CN100532559C (de)
AU (1) AU769385C (de)
CA (1) CA2369491C (de)
DE (1) DE60131498T8 (de)
HK (1) HK1047449A1 (de)
TW (1) TWI303663B (de)
WO (1) WO2001057204A1 (de)

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KR100847385B1 (ko) * 2000-02-02 2008-07-18 안제스에무지 가부시키가이샤 유전자 전달을 위한 바이러스 엔벨로프 벡터
EP1297852A4 (de) * 2000-06-27 2004-12-29 Dnavec Research Inc Viraler vektor zur einbringung von genen in nierenzellen(03.02.03)
EP1690544B1 (de) * 2001-02-20 2017-09-13 AnGes MG, Inc. Pharmazeutische Zusammensetzungen mit einem Decoy und Verfahren zu ihrer Verwendung
WO2003014338A1 (fr) * 2001-08-02 2003-02-20 Anges Mg, Inc. Procede de production d'enveloppes virales inactivees
JPWO2003029475A1 (ja) * 2001-09-28 2005-01-20 株式会社ディナベック研究所 エピトープ結合β2mをコードする哺乳動物細胞感染性ウイルスベクターおよびその利用
DE60231063D1 (de) 2002-02-01 2009-03-19 Anges Mg Inc N zur behandlung von aneurysmen
CA2490357A1 (en) * 2002-06-06 2003-12-18 Anges Mg, Inc. Gene therapeutic for cerebrovascular disorders
EP1535993A4 (de) * 2002-08-27 2007-03-21 Anges Mg Inc VERFAHREN ZUR ÜBERTRAGUNG VON BIOMOLEKüLEN UNTER VERWENDUNG DER VIRUSHÜLLE SOWIE ZUSAMMENSETZUNG UND SYSTEM DAFüR
EP1559780A1 (de) * 2002-10-01 2005-08-03 Dnavec Research Inc. Verfahren zur verstärkung der fremdepitop-präsentation mit mhc klasse i mittels hemmung der tap-aktivität
AU2003280604A1 (en) 2002-11-01 2004-05-25 Anges Mg, Inc. Medicinal preparation having chemotherapeutic encapsulated therein
CA2506894A1 (en) * 2002-11-21 2004-06-03 Genomidea Inc. Method of isolating nucleic acid having desired functional property and kit therefor
JP2004289816A (ja) * 2003-03-06 2004-10-14 Matsushita Electric Ind Co Ltd 遠隔制御装置、遠隔制御方法および被遠隔制御装置
WO2005094878A1 (ja) 2004-03-31 2005-10-13 Genomidea Inc. 抗腫瘍作用を有する組成物
NZ550430A (en) 2004-04-27 2009-06-26 Wellstat Biologics Corp Cancer treatment using viruses and camptothecins
ES2357772T3 (es) 2004-06-14 2011-04-29 Ishihara Sangyo Kaisha, Ltd. Composición liofilizada de envuelta viral inactivada con actividad de fusión de membrana.
WO2007011601A2 (en) * 2005-07-14 2007-01-25 Wellstat Biologics Corporation Cancer treatment using viruses, fluoropyrimidines and camptothecins
US20090214496A1 (en) * 2006-01-30 2009-08-27 Licentia Ltd. Bmx/etk tyrosine kinase gene therapy materials and methods
WO2007088882A1 (ja) 2006-01-31 2007-08-09 Ishihara Sangyo Kaisha, Ltd. エンベロープウイルスの構成成分に親和性を有するポリペプチドと細胞内物質導入への使用
JP2008308440A (ja) * 2007-06-14 2008-12-25 Genomidea Inc 癌治療用薬剤送達ビヒクルおよびその製造方法ならびにそれを用いた製剤
WO2010032764A1 (ja) 2008-09-16 2010-03-25 ジェノミディア株式会社 前立腺癌の治療・予防剤
US8927493B2 (en) 2008-10-10 2015-01-06 Kringle Pharma, Inc. Promoter for regeneration of tendon-bone junction tissue or ligament-bone junction tissue
WO2011046983A2 (en) 2009-10-12 2011-04-21 Smith Holdings, Llc Methods and compositions for modulating gene expression using oligonucleotide based drugs administered in vivo or in vitro
JP4653242B1 (ja) 2010-02-12 2011-03-16 ナノキャリア株式会社 粒子状医薬組成物
BR112012027643A2 (pt) * 2010-05-03 2016-08-16 Glaxosmithkline Biolog Sa métodos para a inativação de um orthomixovírus, para a preparação de uma vacina, e , composição imunogênica
CN103941924B (zh) * 2014-04-25 2016-09-14 锐达互动科技股份有限公司 一种实现红外光编解码的互动投影方法
EP3536329B1 (de) 2016-11-01 2022-08-31 Osaka University Antikrebsmittel mit hvj-e und neutralisierenden antikörpers gegen pd-1
US11413477B2 (en) * 2016-11-22 2022-08-16 Cedars-Sinai Medical Center Transfection and drug delivery
ES2896255T3 (es) 2016-12-06 2022-02-24 Univ Osaka Nuevo agente terapéutico para enfermedades por prionoides
WO2022059703A1 (ja) 2020-09-16 2022-03-24 国立大学法人大阪大学 がん治療用医薬、免疫賦活剤および抗がん物質のスクリーニング方法

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Also Published As

Publication number Publication date
EP1170363A1 (de) 2002-01-09
EP1170363A4 (de) 2002-06-12
EP1170363B1 (de) 2007-11-21
US20030013195A1 (en) 2003-01-16
AU769385C (en) 2004-07-29
US7279333B2 (en) 2007-10-09
HK1047449A1 (zh) 2003-02-21
AU769385B2 (en) 2004-01-22
CA2369491A1 (en) 2001-08-09
AU3057801A (en) 2001-08-14
KR20070059182A (ko) 2007-06-11
KR100847385B1 (ko) 2008-07-18
CN1657103A (zh) 2005-08-24
US20050239188A1 (en) 2005-10-27
CN100542614C (zh) 2009-09-23
US20040219674A1 (en) 2004-11-04
CN101302536A (zh) 2008-11-12
KR20020004987A (ko) 2002-01-16
US6913923B2 (en) 2005-07-05
CA2369491C (en) 2008-09-02
WO2001057204A1 (fr) 2001-08-09
US7803621B2 (en) 2010-09-28
KR100776475B1 (ko) 2007-11-16
CN1365388A (zh) 2002-08-21
DE60131498T8 (de) 2009-01-29
CN100532559C (zh) 2009-08-26
TWI303663B (en) 2008-12-01
DE60131498T2 (de) 2008-10-02

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