DE60130994T2 - Anti-hiv und anti-tumor lysozympeptide sowie fragmente - Google Patents
Anti-hiv und anti-tumor lysozympeptide sowie fragmente Download PDFInfo
- Publication number
- DE60130994T2 DE60130994T2 DE60130994T DE60130994T DE60130994T2 DE 60130994 T2 DE60130994 T2 DE 60130994T2 DE 60130994 T DE60130994 T DE 60130994T DE 60130994 T DE60130994 T DE 60130994T DE 60130994 T2 DE60130994 T2 DE 60130994T2
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- Prior art keywords
- hiv
- lysozyme
- fragment
- seq
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- 239000011589 pyridoxal 5'-phosphate Substances 0.000 description 1
- 229960001327 pyridoxal phosphate Drugs 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 125000003607 serino group Chemical group [H]N([H])[C@]([H])(C(=O)[*])C(O[H])([H])[H] 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- IHQKEDIOMGYHEB-UHFFFAOYSA-M sodium dimethylarsinate Chemical compound [Na+].C[As](C)([O-])=O IHQKEDIOMGYHEB-UHFFFAOYSA-M 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000003595 spectral effect Effects 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 125000000341 threoninyl group Chemical group [H]OC([H])(C([H])([H])[H])C([H])(N([H])[H])C(*)=O 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 125000000430 tryptophan group Chemical class [H]N([H])C(C(=O)O*)C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 230000005570 vertical transmission Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2462—Lysozyme (3.2.1.17)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21670200P | 2000-07-07 | 2000-07-07 | |
| US216702P | 2000-07-07 | ||
| PCT/US2001/021582 WO2002004011A1 (en) | 2000-07-07 | 2001-07-09 | Anti-hiv and anti-tumor peptides and fragments of lysozyme |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60130994D1 DE60130994D1 (de) | 2007-11-29 |
| DE60130994T2 true DE60130994T2 (de) | 2008-07-24 |
Family
ID=22808164
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60130994T Expired - Lifetime DE60130994T2 (de) | 2000-07-07 | 2001-07-09 | Anti-hiv und anti-tumor lysozympeptide sowie fragmente |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7838275B2 (enExample) |
| EP (1) | EP1303291B1 (enExample) |
| JP (1) | JP2004505616A (enExample) |
| AT (1) | ATE375800T1 (enExample) |
| AU (1) | AU2001278884A1 (enExample) |
| CA (1) | CA2415083A1 (enExample) |
| DE (1) | DE60130994T2 (enExample) |
| WO (1) | WO2002004011A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003246119B2 (en) * | 2002-06-28 | 2008-02-21 | Fuso Pharmaceutical Industries, Ltd. | Anti-HIV agent |
| ITMI20061950A1 (it) * | 2006-10-11 | 2008-04-12 | Therapicon Srl | Effetto antimetastatico in condizioni patologiche delle cellule umane |
| US7846430B2 (en) * | 2007-03-02 | 2010-12-07 | Stefano Ferrari | Composition and method for treating bovine papilloma virus in equine |
| JP5806434B1 (ja) | 2014-02-21 | 2015-11-10 | 国立大学法人東京海洋大学 | ノロウィルス不活化剤及びその製造方法、ノロウィルス不活化方法、ノロウィルス不活化用リゾチーム類の製造方法、ノロウィルス感染の予防薬又は治療薬、並びにノロウィルス不活化用皮膚外用剤 |
| KR102232006B1 (ko) | 2016-12-28 | 2021-03-25 | 디아이씨 가부시끼가이샤 | 분산체 및 그것을 사용한 잉크젯용 잉크 조성물, 광변환층, 및 액정 표시 소자 |
| CN110438106B (zh) * | 2019-08-06 | 2021-03-23 | 北京华韵国丰新材料科技有限公司 | 一种人工设计的纳米溶菌酶和纳米溶菌酶的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5583211A (en) * | 1992-10-29 | 1996-12-10 | Beckman Instruments, Inc. | Surface activated organic polymers useful for location - specific attachment of nucleic acids, peptides, proteins and oligosaccharides |
| US5554501A (en) | 1992-10-29 | 1996-09-10 | Beckman Instruments, Inc. | Biopolymer synthesis using surface activated biaxially oriented polypropylene |
| JPH06211692A (ja) * | 1993-01-21 | 1994-08-02 | Nippon Oil Co Ltd | 免疫増強剤 |
| WO1995009176A1 (en) * | 1993-09-28 | 1995-04-06 | Beckman Instruments, Inc. | Biopolymer synthesis utilizing surface activated, organic polymers |
| AU3307497A (en) * | 1996-06-26 | 1998-01-14 | Antigen Express, Inc. | Immunotherapy by modulation of antigen presentation |
| WO1998026747A2 (en) * | 1996-12-17 | 1998-06-25 | Terman David S | Superantigen based methods and compositions for treatment of diseases |
| GB9907366D0 (en) * | 1999-03-30 | 1999-05-26 | Medical Res Council | Method for expressing proteins |
-
2001
- 2001-07-09 JP JP2002508465A patent/JP2004505616A/ja active Pending
- 2001-07-09 CA CA002415083A patent/CA2415083A1/en not_active Abandoned
- 2001-07-09 AT AT01957109T patent/ATE375800T1/de not_active IP Right Cessation
- 2001-07-09 WO PCT/US2001/021582 patent/WO2002004011A1/en not_active Ceased
- 2001-07-09 DE DE60130994T patent/DE60130994T2/de not_active Expired - Lifetime
- 2001-07-09 US US10/487,259 patent/US7838275B2/en not_active Expired - Fee Related
- 2001-07-09 EP EP01957109A patent/EP1303291B1/en not_active Expired - Lifetime
- 2001-07-09 AU AU2001278884A patent/AU2001278884A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2415083A1 (en) | 2002-01-17 |
| EP1303291B1 (en) | 2007-10-17 |
| WO2002004011A1 (en) | 2002-01-17 |
| DE60130994D1 (de) | 2007-11-29 |
| AU2001278884A1 (en) | 2002-01-21 |
| EP1303291A4 (en) | 2005-04-06 |
| ATE375800T1 (de) | 2007-11-15 |
| US20050008631A1 (en) | 2005-01-13 |
| EP1303291A1 (en) | 2003-04-23 |
| JP2004505616A (ja) | 2004-02-26 |
| US7838275B2 (en) | 2010-11-23 |
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| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |