DE60129442D1 - Sulphonsäurederivate von hydroxamsäuren und deren verwendung in medizinischen produkten - Google Patents
Sulphonsäurederivate von hydroxamsäuren und deren verwendung in medizinischen produktenInfo
- Publication number
- DE60129442D1 DE60129442D1 DE60129442T DE60129442T DE60129442D1 DE 60129442 D1 DE60129442 D1 DE 60129442D1 DE 60129442 T DE60129442 T DE 60129442T DE 60129442 T DE60129442 T DE 60129442T DE 60129442 D1 DE60129442 D1 DE 60129442D1
- Authority
- DE
- Germany
- Prior art keywords
- sulphonic acid
- medicinal products
- acid derivates
- hydroxyacrylic acids
- relates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- FEWFXBUNENSNBQ-UHFFFAOYSA-N 2-hydroxyacrylic acid Chemical class OC(=C)C(O)=O FEWFXBUNENSNBQ-UHFFFAOYSA-N 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-N sulfonic acid Chemical compound OS(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 3
- 150000003458 sulfonic acid derivatives Chemical class 0.000 abstract 3
- 239000002158 endotoxin Substances 0.000 abstract 2
- 229920006008 lipopolysaccharide Polymers 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C309/07—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing oxygen atoms bound to the carbon skeleton
- C07C309/09—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing oxygen atoms bound to the carbon skeleton containing etherified hydroxy groups bound to the carbon skeleton
- C07C309/11—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing oxygen atoms bound to the carbon skeleton containing etherified hydroxy groups bound to the carbon skeleton with the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C309/13—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
- C07C309/14—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
- C07C309/15—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton the nitrogen atom of at least one of the amino groups being part of any of the groups, X being a hetero atom, Y being any atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/45—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
- C07C309/51—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000219245 | 2000-07-19 | ||
JP2000219034 | 2000-07-19 | ||
JP2000219245 | 2000-07-19 | ||
JP2000219034 | 2000-07-19 | ||
PCT/JP2001/006275 WO2002006214A1 (fr) | 2000-07-19 | 2001-07-19 | Derives a l'acide sulfonique d'acides hydroxamiques et leur utilisation comme produits medicaux |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60129442D1 true DE60129442D1 (de) | 2007-08-30 |
DE60129442T2 DE60129442T2 (de) | 2008-04-17 |
Family
ID=26596313
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60129442T Expired - Fee Related DE60129442T2 (de) | 2000-07-19 | 2001-07-19 | Sulphonsäurederivate von hydroxamsäuren und deren verwendung in medizinischen produkten |
Country Status (9)
Country | Link |
---|---|
US (1) | US6989401B2 (de) |
EP (1) | EP1306367B1 (de) |
KR (1) | KR100799192B1 (de) |
CN (1) | CN1215052C (de) |
AT (1) | ATE367374T1 (de) |
AU (1) | AU2001272761A1 (de) |
CA (1) | CA2415954A1 (de) |
DE (1) | DE60129442T2 (de) |
WO (1) | WO2002006214A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7829085B2 (en) | 1999-07-14 | 2010-11-09 | Life Sciences Research Partners Vzw | Methods of treating hemostasis disorders using antibodies binding the C1 domain of factor VIII |
WO2004085396A1 (ja) * | 2003-03-26 | 2004-10-07 | Mitsubishi Pharma Corporation | 虚血再灌流障害の予防または治療剤、臓器保存剤およびスクリーニング方法 |
US20070010573A1 (en) * | 2003-06-23 | 2007-01-11 | Xianqi Kong | Methods and compositions for treating amyloid-related diseases |
EP1706079B1 (de) | 2003-08-14 | 2013-02-20 | ThromboGenics N.V. | Antikörper gegen faktor viii mit modifizierter glykosilierung in der variablen region |
WO2005037265A1 (ja) * | 2003-10-17 | 2005-04-28 | Mitsubishi Pharma Corporation | 併用薬剤 |
PL1685104T3 (pl) * | 2003-11-17 | 2008-03-31 | Wyeth Corp | Sposoby wytwarzania N-podstawionych ftalimidów |
EP1713541B1 (de) | 2004-02-04 | 2017-03-22 | AM-Pharma B.V. | Verwendung von alkalischer phosphatase für die entgiftung von lps |
EP1836161B1 (de) | 2004-12-22 | 2016-07-20 | BHI Limited Partnership | Verfahren und zusammensetzungen zur behandlung von amyloidassoziierten krankheiten |
DK3851447T3 (da) * | 2006-10-12 | 2023-12-04 | Bellus Health Inc | Fremgangsmåder, forbindelser, sammensætninger og vehikler til administration af 3-amino-1-propansulfonsyre |
WO2014015235A2 (en) * | 2012-07-20 | 2014-01-23 | Academia Sinica | 3,5,n-trihydroxy-alkanamide and derivatives: method for making same and use thereof |
BR112016017041B1 (pt) | 2014-01-24 | 2023-09-26 | Am-Pharma B.V | Proteína quimérica isolada, vetor, método para produzir a proteína quimérica isolada e composição |
PL3461891T3 (pl) | 2014-01-24 | 2020-11-16 | Am-Pharma B.V. | Przetwarzanie końcowe fosfatazy alkalicznej |
RU2765098C2 (ru) * | 2017-02-28 | 2022-01-25 | Иммуноджен, Инк. | Производные майтанзиноида с саморасщепляющимися пептидными линкерами и их конъюгаты |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8827305D0 (en) | 1988-11-23 | 1988-12-29 | British Bio Technology | Compounds |
CA2058797A1 (en) * | 1991-02-01 | 1992-08-02 | Michael John Broadhurst | Amino acid derivatives |
GB9102635D0 (en) | 1991-02-07 | 1991-03-27 | British Bio Technology | Compounds |
US5318964A (en) | 1992-06-11 | 1994-06-07 | Hoffmann-La Roche Inc. | Hydroxamic derivatives and pharmaceutical compositions |
GB9223904D0 (en) | 1992-11-13 | 1993-01-06 | British Bio Technology | Inhibition of cytokine production |
NZ262447A (en) | 1993-03-16 | 1996-07-26 | British Biotech Pharm | Hydroxamic acid derivatives and their use as pharmaceutical agents |
JPH07157470A (ja) | 1993-03-18 | 1995-06-20 | Otsuka Pharmaceut Co Ltd | カルボスチリル誘導体 |
DE69632821T2 (de) * | 1995-04-25 | 2005-08-25 | Daiichi Fine Chemical Co., Ltd., Takaoka | In wasser hochlöslicher metalloproteinase-inhibitor |
AU3849699A (en) * | 1998-05-22 | 1999-12-13 | Welfide Corporation | Hydroxamic acid derivatives and medicinal utilization thereof |
US6797505B2 (en) * | 1998-05-27 | 2004-09-28 | Cell Genesys, Inc. | Recombinant AAV vectors for gene therapy of hemophilia A |
-
2001
- 2001-07-19 CA CA002415954A patent/CA2415954A1/en not_active Abandoned
- 2001-07-19 DE DE60129442T patent/DE60129442T2/de not_active Expired - Fee Related
- 2001-07-19 US US10/333,266 patent/US6989401B2/en not_active Expired - Fee Related
- 2001-07-19 CN CNB018130518A patent/CN1215052C/zh not_active Expired - Fee Related
- 2001-07-19 KR KR1020037000808A patent/KR100799192B1/ko not_active IP Right Cessation
- 2001-07-19 WO PCT/JP2001/006275 patent/WO2002006214A1/ja active IP Right Grant
- 2001-07-19 AU AU2001272761A patent/AU2001272761A1/en not_active Abandoned
- 2001-07-19 AT AT01951935T patent/ATE367374T1/de not_active IP Right Cessation
- 2001-07-19 EP EP01951935A patent/EP1306367B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
KR100799192B1 (ko) | 2008-01-31 |
EP1306367A4 (de) | 2004-06-09 |
CN1443158A (zh) | 2003-09-17 |
EP1306367A1 (de) | 2003-05-02 |
AU2001272761A1 (en) | 2002-01-30 |
ATE367374T1 (de) | 2007-08-15 |
WO2002006214A1 (fr) | 2002-01-24 |
US20030176486A1 (en) | 2003-09-18 |
EP1306367B1 (de) | 2007-07-18 |
CA2415954A1 (en) | 2003-01-17 |
US6989401B2 (en) | 2006-01-24 |
DE60129442T2 (de) | 2008-04-17 |
CN1215052C (zh) | 2005-08-17 |
KR20030029628A (ko) | 2003-04-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |