DE60124581D1 - Triazoloä4,5-düpyrimidinderivate als antithrombotische verbindungen - Google Patents

Triazoloä4,5-düpyrimidinderivate als antithrombotische verbindungen

Info

Publication number
DE60124581D1
DE60124581D1 DE60124581T DE60124581T DE60124581D1 DE 60124581 D1 DE60124581 D1 DE 60124581D1 DE 60124581 T DE60124581 T DE 60124581T DE 60124581 T DE60124581 T DE 60124581T DE 60124581 D1 DE60124581 D1 DE 60124581D1
Authority
DE
Germany
Prior art keywords
düpyrimidin
derivatives
antithrombotic compounds
compounds
antithrombotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60124581T
Other languages
English (en)
Other versions
DE60124581T2 (de
Inventor
Roger Brown
Simon Guile
Garry Pairaudeau
Brian Springthorpe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of DE60124581D1 publication Critical patent/DE60124581D1/de
Publication of DE60124581T2 publication Critical patent/DE60124581T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60124581T 2000-11-09 2001-11-07 Triazolo[4,5-d]pyrimidinderivate als antithrombotische verbindungen Expired - Fee Related DE60124581T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0004099A SE0004099D0 (sv) 2000-11-09 2000-11-09 Novel compounds
SE0004099 2000-11-09
PCT/SE2001/002471 WO2002038570A1 (en) 2000-11-09 2001-11-07 Novel compounds

Publications (2)

Publication Number Publication Date
DE60124581D1 true DE60124581D1 (de) 2006-12-28
DE60124581T2 DE60124581T2 (de) 2007-06-28

Family

ID=20281756

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60124581T Expired - Fee Related DE60124581T2 (de) 2000-11-09 2001-11-07 Triazolo[4,5-d]pyrimidinderivate als antithrombotische verbindungen

Country Status (10)

Country Link
US (1) US7034032B2 (de)
EP (1) EP1335919B1 (de)
JP (1) JP4202752B2 (de)
AT (1) ATE345343T1 (de)
AU (1) AU2002214467A1 (de)
DE (1) DE60124581T2 (de)
ES (1) ES2274908T3 (de)
HK (1) HK1056362A1 (de)
SE (1) SE0004099D0 (de)
WO (1) WO2002038570A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0219746D0 (en) * 2002-08-23 2002-10-02 Inst Of Ex Botany Ascr Azapurine derivatives
GB0512844D0 (en) * 2005-06-23 2005-08-03 Novartis Ag Organic compounds
US7734944B2 (en) * 2006-06-27 2010-06-08 International Business Machines Corporation Mechanism for windaging of a double rate driver
US7752475B2 (en) * 2006-06-27 2010-07-06 International Business Machines Corporation Late data launch for a double data rate elastic interface
US7566722B2 (en) 2006-10-31 2009-07-28 Janssen Pharmaceutica, N.V. Triazolopyrimidine derivatives as ADP P2Y12 receptor antagonists

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8826205D0 (en) * 1988-11-09 1988-12-14 Wellcome Found Heterocyclic compounds
TW530058B (en) * 1997-07-22 2003-05-01 Astra Pharma Prod Triazolo [4,5-d]pyrimidine compounos and their use and process for preparation

Also Published As

Publication number Publication date
US7034032B2 (en) 2006-04-25
EP1335919A1 (de) 2003-08-20
WO2002038570A1 (en) 2002-05-16
JP2004513172A (ja) 2004-04-30
HK1056362A1 (en) 2004-02-13
ATE345343T1 (de) 2006-12-15
SE0004099D0 (sv) 2000-11-09
AU2002214467A1 (en) 2002-05-21
EP1335919B1 (de) 2006-11-15
DE60124581T2 (de) 2007-06-28
JP4202752B2 (ja) 2008-12-24
ES2274908T3 (es) 2007-06-01
US20040023988A1 (en) 2004-02-05

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Legal Events

Date Code Title Description
8381 Inventor (new situation)

Inventor name: BROWN, ROGER, SEAGRAVE, LEICESTERSHIRE LE12 7L, GB

Inventor name: GUILE, SIMON, LOUGHBOROUGH, LEICESTERSHIRE LE1, GB

Inventor name: PAIRAUDEAU, GARRY, LOUGHBOROUGH, LEICESTERSHIR, GB

Inventor name: SPRINGTHORPE, BRIAN, LOUGHBOROUGH, LEICESTERSH, GB

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee