DE60121096D1 - Methode zur Behandlung von Fettsucht anhand eines Neurotensinreceptor-Liganden - Google Patents
Methode zur Behandlung von Fettsucht anhand eines Neurotensinreceptor-LigandenInfo
- Publication number
- DE60121096D1 DE60121096D1 DE60121096T DE60121096T DE60121096D1 DE 60121096 D1 DE60121096 D1 DE 60121096D1 DE 60121096 T DE60121096 T DE 60121096T DE 60121096 T DE60121096 T DE 60121096T DE 60121096 D1 DE60121096 D1 DE 60121096D1
- Authority
- DE
- Germany
- Prior art keywords
- receptor ligand
- neurotensin receptor
- obesity
- treatment
- relates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Revoked
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19995100P | 2000-04-27 | 2000-04-27 | |
US199951 | 2000-04-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60121096D1 true DE60121096D1 (de) | 2006-08-10 |
DE60121096T2 DE60121096T2 (de) | 2006-12-07 |
Family
ID=22739686
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60121096T Revoked DE60121096T2 (de) | 2000-04-27 | 2001-04-27 | Methode zur Behandlung von Fettsucht anhand eines Neurotensinreceptor-Liganden |
Country Status (13)
Country | Link |
---|---|
US (1) | US6699832B2 (de) |
EP (1) | EP1157695B1 (de) |
JP (1) | JP2002275092A (de) |
KR (1) | KR20010098829A (de) |
AT (1) | ATE331518T1 (de) |
AU (1) | AU3888801A (de) |
CA (1) | CA2345180A1 (de) |
DE (1) | DE60121096T2 (de) |
ES (1) | ES2264679T3 (de) |
HU (1) | HUP0101666A3 (de) |
IL (1) | IL142707A0 (de) |
NZ (1) | NZ511354A (de) |
ZA (1) | ZA200103365B (de) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8815951B2 (en) * | 1996-08-13 | 2014-08-26 | The Regents Of The University Of California | Inhibitors of epoxide hydrolases for the treatment of inflammation |
US6693130B2 (en) * | 1999-02-18 | 2004-02-17 | Regents Of The University Of California | Inhibitors of epoxide hydrolases for the treatment of hypertension |
GB0107383D0 (en) * | 2001-03-23 | 2001-05-16 | Univ Edinburgh | Lipid profile modulation |
EP1370268B1 (de) * | 2001-03-23 | 2009-07-15 | Corcept Therapeutics, Inc. | Verfahren zur behandlung von stressbedingten erkrankungen unter verwendung von glucocorticoid-rezepto-spezifischen antagonisten |
GB0121709D0 (en) * | 2001-09-07 | 2001-10-31 | Imp College Innovations Ltd | Food inhibition agent |
DE60230818D1 (de) * | 2001-09-24 | 2009-02-26 | Imp Innovations Ltd | Pyy3-36 zur zur reduzierung oder vorbeugung von fettleibigkeit |
CA2471363C (en) | 2001-12-21 | 2014-02-11 | Human Genome Sciences, Inc. | Albumin fusion proteins |
US8058233B2 (en) * | 2002-01-10 | 2011-11-15 | Oregon Health And Science University | Modification of feeding behavior using PYY and GLP-1 |
BR0308904A (pt) * | 2002-04-10 | 2005-05-03 | Lilly Co Eli | Método de tratamento de gastroparesia, e, uso de um composto de glp-1 |
WO2003093829A1 (en) * | 2002-05-02 | 2003-11-13 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with neurotensin receptor 2 (nt2) |
AU2003229736A1 (en) * | 2002-05-02 | 2003-11-17 | Bayer Aktiengesellschaft | Diagnostics and therapeutics for diseases associated with neurotensin receptor 1 (nt1) |
JP2006506366A (ja) * | 2002-10-18 | 2006-02-23 | ファイザー・プロダクツ・インク | カンナビノイド受容体リガンドおよびその使用方法 |
US8066997B2 (en) * | 2002-12-20 | 2011-11-29 | Anders Nykjaer | Modulation of activity of neurotrophins |
GB0300571D0 (en) * | 2003-01-10 | 2003-02-12 | Imp College Innovations Ltd | Modification of feeding behaviour |
JP2006519229A (ja) * | 2003-02-13 | 2006-08-24 | アルバート・アインシュタイン・カレッジ・オヴ・メディシン・オヴ・イェシヴァ・ユニヴァーシティ | 視床下部内の長鎖脂肪アシルCoAレベルの変調による摂食量およびグルコース産生量の調節 |
US20050222040A1 (en) * | 2004-04-05 | 2005-10-06 | Blm Group, Inc. | Vertebrate peptide modulators of lipid metabolism |
WO2006041922A2 (en) * | 2004-10-08 | 2006-04-20 | Dara Biosciences, Inc. | Agents and methods for administration to the central nervous system |
WO2006088798A2 (en) * | 2005-02-14 | 2006-08-24 | Albert Einstein College Of Medicine Of Yeshiva University | Modulation of hypothalamic atp-sensitive potassium channels |
GB0511986D0 (en) * | 2005-06-13 | 2005-07-20 | Imp College Innovations Ltd | Novel compounds and their effects on feeding behaviour |
TWI428346B (zh) * | 2006-12-13 | 2014-03-01 | Imp Innovations Ltd | 新穎化合物及其等對進食行為影響 |
LT3225251T (lt) * | 2006-12-21 | 2020-04-10 | H. Lundbeck A/S | Proneurotrofinų veiklos moduliavimas |
WO2009033808A2 (en) * | 2007-09-11 | 2009-03-19 | Mondobiotech Laboratories Ag | Use of a peptide as a therapeutic agent |
US20100173829A1 (en) * | 2008-11-07 | 2010-07-08 | Aston University | Glycoproteins Having Lipid Mobilizing Properties and Therapeutic Uses Thereof |
JP5759379B2 (ja) | 2008-12-05 | 2015-08-05 | アンジオケム インコーポレーテッド | ニューロテンシンまたはニューロテンシンアナログおよびその使用 |
WO2011156557A2 (en) * | 2010-06-11 | 2011-12-15 | Thomas James B | Compounds active at the neurotensin receptor |
RU2013103763A (ru) | 2010-07-02 | 2014-08-10 | Ангиохем Инк. | Короткие и содержащие d-аминокислоты полипептиды для терапевтических конъюгатов и их применения |
US8476221B2 (en) * | 2011-03-18 | 2013-07-02 | Halimed Pharmaceuticals, Inc. | Methods and compositions for the treatment of metabolic disorders |
CN103308670B (zh) * | 2012-03-08 | 2017-06-09 | 思芬构技术有限公司 | 用于预测对象患糖尿病和/或代谢综合征的风险的方法 |
MY188344A (en) | 2012-03-09 | 2021-12-01 | Biotropics Malaysia Berhad | Extract formulations of rhodamnia cinerea and uses thereof |
US9822366B2 (en) | 2012-11-02 | 2017-11-21 | The Brigham And Women's Hospital, Inc. | Sortilin 1 is a novel inducer of vascular calcification |
WO2014071128A1 (en) | 2012-11-02 | 2014-05-08 | The Brigham And Women's Hospital, Inc. | Macrophage-derived matrix vesicles: an alternative mechanism for microcalcification in atherosclerotic plaques |
SI3380495T1 (sl) * | 2015-11-24 | 2022-01-31 | Transfert Plus, S.E.C. | Peptidne spojine in peptidni konjugati za zdravljenje raka z receptorsko posredovano kemoterapijo |
US10473670B2 (en) * | 2016-02-25 | 2019-11-12 | University Of Kentucky Research Foundation | Method of predicting obesity comprising measuring neurotensin |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4110321A (en) | 1976-07-12 | 1978-08-29 | Folkers Karl | Synthetic tridecapeptide [Gln4 ]-neurotensin having hormonal activity |
US5217953A (en) | 1990-11-30 | 1993-06-08 | The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services | Vasoactive intestinal peptide antagonist |
US5250558A (en) | 1992-01-28 | 1993-10-05 | Merck & Co., Inc. | Substituted triazolinones, triazolinethiones, and triazolinimines as neurotensin antagonists used to treat psychosis |
US5204354A (en) | 1992-02-14 | 1993-04-20 | Merck & Co., Inc. | Substituted quinazolinones as neurotensin antagonists useful in the treatment of CNS disorders |
US5407916A (en) | 1993-02-16 | 1995-04-18 | Warner-Lambert Company | Neurotensin mimetics as central nervous system agents |
FR2711140B1 (fr) | 1993-10-12 | 1996-01-05 | Sanofi Sa | 1-Naphtylpyrazole-3-carboxamides substitués actifs sur la neurotensine, leur préparation, les compositions pharmaceutiques en contenant. |
FR2760750B1 (fr) | 1997-03-17 | 1999-05-28 | Sanofi Sa | Recepteur humain a la neurotensine de type 2(hnt-r2) |
US6008050A (en) | 1997-04-02 | 1999-12-28 | Smithkline Beecham Corporation | Human neurotensin receptor type 2 and splice variants thereof |
US6274720B1 (en) * | 1997-12-31 | 2001-08-14 | Incyte Genomics, Inc. | Human preproneurotensin/neuromedin N |
US6420137B1 (en) | 1998-11-25 | 2002-07-16 | American Home Products Corporation | Nucleic acid encoding human neurotensin subtype 2 receptor |
-
2001
- 2001-04-19 IL IL14270701A patent/IL142707A0/xx unknown
- 2001-04-24 KR KR1020010021980A patent/KR20010098829A/ko not_active Application Discontinuation
- 2001-04-24 AU AU38888/01A patent/AU3888801A/en not_active Abandoned
- 2001-04-24 US US09/841,276 patent/US6699832B2/en not_active Expired - Fee Related
- 2001-04-25 CA CA002345180A patent/CA2345180A1/en not_active Abandoned
- 2001-04-25 ZA ZA200103365A patent/ZA200103365B/xx unknown
- 2001-04-26 HU HU0101666A patent/HUP0101666A3/hu unknown
- 2001-04-26 NZ NZ511354A patent/NZ511354A/xx unknown
- 2001-04-27 EP EP01303855A patent/EP1157695B1/de not_active Revoked
- 2001-04-27 DE DE60121096T patent/DE60121096T2/de not_active Revoked
- 2001-04-27 AT AT01303855T patent/ATE331518T1/de not_active IP Right Cessation
- 2001-04-27 JP JP2001130680A patent/JP2002275092A/ja active Pending
- 2001-04-27 ES ES01303855T patent/ES2264679T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
NZ511354A (en) | 2003-03-28 |
ATE331518T1 (de) | 2006-07-15 |
KR20010098829A (ko) | 2001-11-08 |
JP2002275092A (ja) | 2002-09-25 |
HU0101666D0 (en) | 2001-06-28 |
CA2345180A1 (en) | 2001-10-27 |
HUP0101666A2 (hu) | 2002-02-28 |
US6699832B2 (en) | 2004-03-02 |
DE60121096T2 (de) | 2006-12-07 |
IL142707A0 (en) | 2002-03-10 |
ZA200103365B (en) | 2002-10-25 |
EP1157695A1 (de) | 2001-11-28 |
AU3888801A (en) | 2001-11-01 |
EP1157695B1 (de) | 2006-06-28 |
HUP0101666A3 (en) | 2003-03-28 |
ES2264679T3 (es) | 2007-01-16 |
US20010046956A1 (en) | 2001-11-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent | ||
8331 | Complete revocation |