DE60118418D1 - Maurotoxin, pi1 und hstx1 derivate - Google Patents

Maurotoxin, pi1 und hstx1 derivate

Info

Publication number
DE60118418D1
DE60118418D1 DE60118418T DE60118418T DE60118418D1 DE 60118418 D1 DE60118418 D1 DE 60118418D1 DE 60118418 T DE60118418 T DE 60118418T DE 60118418 T DE60118418 T DE 60118418T DE 60118418 D1 DE60118418 D1 DE 60118418D1
Authority
DE
Germany
Prior art keywords
derivatives
residue
maurotoxin
replaced
disulfide bridge
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60118418T
Other languages
English (en)
Other versions
DE60118418T2 (de
Inventor
Jean-Marc Sabatier
Kamel Mabrouk
Herve Rochat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cellpep SA
Original Assignee
Cellpep SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0021639A external-priority patent/GB0021639D0/en
Priority claimed from GB0024538A external-priority patent/GB0024538D0/en
Application filed by Cellpep SA filed Critical Cellpep SA
Publication of DE60118418D1 publication Critical patent/DE60118418D1/de
Application granted granted Critical
Publication of DE60118418T2 publication Critical patent/DE60118418T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43522—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from scorpions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DE60118418T 2000-09-04 2001-09-03 Maurotoxin, pi1 und hstx1 derivate Expired - Lifetime DE60118418T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0021639 2000-09-04
GB0021639A GB0021639D0 (en) 2000-09-04 2000-09-04 Maurotoxin derivatives
GB0024538A GB0024538D0 (en) 2000-10-06 2000-10-06 Maurotoxin pil and hstx1 derivatives
GB0024538 2000-10-06
PCT/EP2001/010173 WO2002020596A2 (en) 2000-09-04 2001-09-03 Maurotoxin, pi1 and hstx1 derivatives

Publications (2)

Publication Number Publication Date
DE60118418D1 true DE60118418D1 (de) 2006-05-18
DE60118418T2 DE60118418T2 (de) 2007-01-11

Family

ID=26244958

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60118418T Expired - Lifetime DE60118418T2 (de) 2000-09-04 2001-09-03 Maurotoxin, pi1 und hstx1 derivate

Country Status (7)

Country Link
US (2) US20040039167A1 (de)
EP (1) EP1315747B1 (de)
AT (1) ATE321778T1 (de)
AU (1) AU2002212201A1 (de)
DE (1) DE60118418T2 (de)
ES (1) ES2261491T3 (de)
WO (1) WO2002020596A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0414272D0 (en) * 2004-06-25 2004-07-28 Cellpep Sa OsK1 derivatives
US7825093B2 (en) 2006-10-25 2010-11-02 Amgen Inc. Methods of using OSK1 peptide analogs
CA2840407A1 (en) * 2007-05-22 2008-12-18 Amgen Inc. Compositions and methods for producing bioactive fusion proteins
DE202013104200U1 (de) 2013-09-13 2013-10-10 Flühs Drehtechnik GmbH Einhandhebelkartusche
AU2013404615B2 (en) 2013-10-28 2018-05-17 Baylor College Of Medicine Novel scorpion toxin analogue and method for treating autoimmune diseases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993008274A1 (en) * 1991-10-12 1993-04-29 The Regents Of The University Of California Use of thiol redox proteins for reducing disulfide bonds
US6187579B1 (en) * 1993-10-28 2001-02-13 Carlsberg A/S Customized proteases
EP0912726A4 (de) * 1996-05-10 2001-07-18 Phylomed Corp Verfahren zur oxidation von disulfid-bindungen durch gebrauch von ozon
GB9627115D0 (en) * 1996-12-31 1997-02-19 Centre Nat Rech Scient Alpha-amino-butyrate derivatives of venoms

Also Published As

Publication number Publication date
ATE321778T1 (de) 2006-04-15
ES2261491T3 (es) 2006-11-16
US20090062198A1 (en) 2009-03-05
EP1315747A2 (de) 2003-06-04
US7829666B2 (en) 2010-11-09
US20040039167A1 (en) 2004-02-26
WO2002020596A2 (en) 2002-03-14
AU2002212201A1 (en) 2002-03-22
EP1315747B1 (de) 2006-03-29
WO2002020596A3 (en) 2002-08-01
DE60118418T2 (de) 2007-01-11

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