DE60115031D1 - Spermatophyte pflanzenextrakte mit antitumoraler wirkung - Google Patents
Spermatophyte pflanzenextrakte mit antitumoraler wirkungInfo
- Publication number
- DE60115031D1 DE60115031D1 DE60115031T DE60115031T DE60115031D1 DE 60115031 D1 DE60115031 D1 DE 60115031D1 DE 60115031 T DE60115031 T DE 60115031T DE 60115031 T DE60115031 T DE 60115031T DE 60115031 D1 DE60115031 D1 DE 60115031D1
- Authority
- DE
- Germany
- Prior art keywords
- spermatophyte
- glucosidated
- viniferine
- res
- plant extracts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000000259 anti-tumor effect Effects 0.000 title abstract 2
- 239000000419 plant extract Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- XAXVWWYPKOGXSY-UHFFFAOYSA-N (+)-cis-Vitisin A Natural products C1=CC(O)=CC=C1C1C(C=2C=C(O)C=C(O)C=2)C2=C(C=CC=3C=C(C(O)=CC=3)C3C=4C=C(O)C=C5OC(C(C=45)C4=CC(O)=CC(O)=C4C3C=3C=CC(O)=CC=3)C=3C=CC(O)=CC=3)C=C(O)C=C2O1 XAXVWWYPKOGXSY-UHFFFAOYSA-N 0.000 abstract 1
- FQWLMRXWKZGLFI-YVYUXZJTSA-N (-)-trans-epsilon-viniferin Chemical compound C1=CC(O)=CC=C1\C=C\C1=CC(O)=CC2=C1[C@@H](C=1C=C(O)C=C(O)C=1)[C@H](C=1C=CC(O)=CC=1)O2 FQWLMRXWKZGLFI-YVYUXZJTSA-N 0.000 abstract 1
- PHIHHTIYURVLDB-UHFFFAOYSA-N H-gnetine Natural products C1=CC(O)=CC=C1C=CC1=C(C(C(O2)C=3C=CC(O)=CC=3)C=3C=C(O)C=C(O)C=3)C2=CC2=C1C(C=1C=C(O)C=C(O)C=1)C(C=1C=CC(O)=CC=1)O2 PHIHHTIYURVLDB-UHFFFAOYSA-N 0.000 abstract 1
- LHUHHURKGTUZHU-UHFFFAOYSA-N ampelopsin A Natural products C12=C(O)C=C(O)C=C2C(C=23)C(C=4C=CC(O)=CC=4)OC3=CC(O)=CC=2C(O)C1C1=CC=C(O)C=C1 LHUHHURKGTUZHU-UHFFFAOYSA-N 0.000 abstract 1
- FQWLMRXWKZGLFI-UHFFFAOYSA-N cis epsilon-viniferine Natural products C1=CC(O)=CC=C1C=CC1=CC(O)=CC2=C1C(C=1C=C(O)C=C(O)C=1)C(C=1C=CC(O)=CC=1)O2 FQWLMRXWKZGLFI-UHFFFAOYSA-N 0.000 abstract 1
- WZKKRZSJTLGPHH-UHFFFAOYSA-N cis-vitisin B Natural products Oc1ccc(cc1)C2Oc3cc(O)cc(C=C/c4ccc5OC(C(c5c4)c6cc(O)cc7OC(C(c8cc(O)cc(O)c8)c67)c9ccc(O)cc9)c%10ccc(O)cc%10)c3C2c%11cc(O)cc(O)c%11 WZKKRZSJTLGPHH-UHFFFAOYSA-N 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- YQQUILZPDYJDQJ-KGDQSQJYSA-N hopeaphenol Chemical compound C1=CC(O)=CC=C1[C@H](O1)[C@@H]2C3=CC(O)=CC(O)=C3[C@@H](C=3C=CC(O)=CC=3)[C@H]([C@@H]3C=4C=C(O)C=C5O[C@H]([C@@H](C=45)C4=CC(O)=CC(O)=C4[C@H]3C=3C=CC(O)=CC=3)C=3C=CC(O)=CC=3)C3=C2C1=CC(O)=C3 YQQUILZPDYJDQJ-KGDQSQJYSA-N 0.000 abstract 1
- YQQUILZPDYJDQJ-PLGGFYDZSA-N hopeaphenol Natural products Oc1ccc(cc1)[C@@H]2Oc3cc(O)cc4[C@H]([C@@H]5[C@@H](c6ccc(O)cc6)c7c(O)cc(O)cc7[C@@H]8[C@H](Oc9cc(O)cc5c89)c%10ccc(O)cc%10)[C@@H](c%11ccc(O)cc%11)c%12c(O)cc(O)cc%12[C@@H]2c34 YQQUILZPDYJDQJ-PLGGFYDZSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- DQRZXILSJKXVQV-UHFFFAOYSA-N nepalensinol G Natural products Oc1ccc(cc1)C2OC3=CC(=O)C(=O)C4=C3C2c5cc(O)cc(O)c5C(C4C6C(c7ccc(O)cc7)c8c(O)cc(O)cc8C9C(Oc%10cc(O)cc6c9%10)c%11ccc(O)cc%11)c%12ccc(O)cc%12 DQRZXILSJKXVQV-UHFFFAOYSA-N 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- PJANXHGTPQOBST-UHFFFAOYSA-N stilbene Chemical group C=1C=CC=CC=1C=CC1=CC=CC=C1 PJANXHGTPQOBST-UHFFFAOYSA-N 0.000 abstract 1
- 150000003436 stilbenoids Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2000RM000293A IT1317033B1 (it) | 2000-05-30 | 2000-05-30 | Metodo di estrazione di prodotti ad attivita' farmaceutica da piantespermatofite, prodotti cosi' ottenuti e loro impiego in medicina, in |
| ITRM000293 | 2000-05-30 | ||
| PCT/IB2001/000981 WO2001091763A2 (en) | 2000-05-30 | 2001-05-29 | Extracts from spermatophyte plants with antitumor activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60115031D1 true DE60115031D1 (de) | 2005-12-22 |
| DE60115031T2 DE60115031T2 (de) | 2006-08-24 |
Family
ID=11454758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60115031T Expired - Lifetime DE60115031T2 (de) | 2000-05-30 | 2001-05-29 | Spermatophyte pflanzenextrakte mit antitumoraler wirkung |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20040052879A1 (de) |
| EP (1) | EP1292319B1 (de) |
| AT (1) | ATE309814T1 (de) |
| AU (1) | AU2001260540A1 (de) |
| DE (1) | DE60115031T2 (de) |
| DK (1) | DK1292319T3 (de) |
| ES (1) | ES2253378T3 (de) |
| IT (1) | IT1317033B1 (de) |
| WO (1) | WO2001091763A2 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050042314A1 (en) | 2003-08-22 | 2005-02-24 | National Yang-Ming University | Extracts of Polygonum multiflorum Thunb., and preparation process and uses of the same |
| US7744937B2 (en) * | 2005-08-09 | 2010-06-29 | Kraft Foods Global Brands Llc | Chemoprotectants from crucifer seeds and sprouts |
| FR2896990B1 (fr) * | 2006-02-03 | 2008-05-02 | Lvmh Rech | Composition protectrice et regenerante |
| BRPI0806897B1 (pt) * | 2007-01-30 | 2022-09-27 | União Brasileira De Educação E Assistência - Mantenedora Da Puc Rs | Processo de obtenção de trans-resveratrol e/ou emodina e uso |
| US20080311192A1 (en) * | 2007-06-12 | 2008-12-18 | Kraft Foods Holdings, Inc. | Enteric-Coated Glucosinolates And Beta-Thioglucosidases |
| US20080311276A1 (en) * | 2007-06-12 | 2008-12-18 | Kraft Foods Holdings, Inc. | Production of Glucosinolates from Agricultural By-Products & Waste |
| ITFI20080019A1 (it) | 2008-02-11 | 2009-08-12 | Glures S R L | Formulazioni comprendenti piceide e resveratrolo atte a prevenire e inibire la perossidazione lipidica. |
| US7824714B2 (en) * | 2008-06-13 | 2010-11-02 | Development Center For Biotechnology | Chinese herb extract for treating dementia and preparation method thereof |
| TWI389699B (zh) * | 2009-02-13 | 2013-03-21 | Univ Kaohsiung Medical | 用於誘導細胞凋亡之樟芝子實體乙醇萃取物及其製備方法 |
| DE102009054984A1 (de) | 2009-12-18 | 2011-06-22 | Evonik Degussa GmbH, 45128 | Verfahren zur Isolierung von Stilbenoiden aus Lösungsmitteln |
| DE102010028874A1 (de) | 2010-05-11 | 2011-11-17 | Evonik Degussa Gmbh | Verfahren zur Isolierung von Stilbenoiden aus Lösungsmitteln |
| CN103458921B (zh) | 2011-02-22 | 2016-05-11 | 考迪尔种子公司 | 喷雾干燥的黑芥子酶和用于生产异硫氰酸酯的用途 |
| CN104792917B (zh) * | 2015-04-24 | 2017-02-22 | 九寨沟天然药业集团有限责任公司 | 一种乙肝扶正胶囊的检测方法 |
| CN108697750A (zh) | 2015-10-01 | 2018-10-23 | 光动力公司 | 新型虎杖提取物及它们作为光动力灭活剂的用途 |
| US10905703B2 (en) * | 2015-12-04 | 2021-02-02 | Huanggang normal university | Preparation of a composition containing stilbene glycoside |
| CN109553623B (zh) * | 2019-01-21 | 2020-07-03 | 深圳市人民医院 | 一种单萜类化合物及其提取方法和应用 |
| CN110824075A (zh) * | 2019-10-16 | 2020-02-21 | 西北农林科技大学 | 葡萄香气糖苷的提取纯化方法及其建库鉴定量化方法 |
| CN114478700B (zh) * | 2022-02-22 | 2023-09-08 | 南京医科大学 | 鸡冠花子中荨麻科类型环肽的制备方法及其在抗肿瘤药物中的应用 |
| CN115184500A (zh) * | 2022-07-19 | 2022-10-14 | 康臣药业(霍尔果斯)有限公司 | 中药组合物的质量检测方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6414037B1 (en) * | 1998-01-09 | 2002-07-02 | Pharmascience | Pharmaceutical formulations of resveratrol and methods of use thereof |
| US6022901A (en) * | 1998-05-13 | 2000-02-08 | Pharmascience Inc. | Administration of resveratrol to prevent or treat restenosis following coronary intervention |
| US6361815B1 (en) * | 1998-12-21 | 2002-03-26 | Pure World Botanicals, Inc. | Products comprising trihydroxystilbenes and derivatives thereof and methods for their manufacture and use |
| FR2795965B1 (fr) * | 1999-07-08 | 2002-12-27 | Actichem | Procede de fabrication d'un extrait naturel de la vigne concentre en reseratrol et produits |
-
2000
- 2000-05-30 IT IT2000RM000293A patent/IT1317033B1/it active
-
2001
- 2001-05-29 AU AU2001260540A patent/AU2001260540A1/en not_active Abandoned
- 2001-05-29 US US10/296,419 patent/US20040052879A1/en not_active Abandoned
- 2001-05-29 ES ES01934245T patent/ES2253378T3/es not_active Expired - Lifetime
- 2001-05-29 EP EP01934245A patent/EP1292319B1/de not_active Expired - Lifetime
- 2001-05-29 AT AT01934245T patent/ATE309814T1/de active
- 2001-05-29 DK DK01934245T patent/DK1292319T3/da active
- 2001-05-29 DE DE60115031T patent/DE60115031T2/de not_active Expired - Lifetime
- 2001-05-29 WO PCT/IB2001/000981 patent/WO2001091763A2/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001091763A3 (en) | 2002-08-15 |
| US20040052879A1 (en) | 2004-03-18 |
| IT1317033B1 (it) | 2003-05-26 |
| ATE309814T1 (de) | 2005-12-15 |
| WO2001091763A2 (en) | 2001-12-06 |
| ITRM20000293A0 (it) | 2000-05-30 |
| WO2001091763A9 (en) | 2003-05-08 |
| EP1292319B1 (de) | 2005-11-16 |
| EP1292319A2 (de) | 2003-03-19 |
| DE60115031T2 (de) | 2006-08-24 |
| DK1292319T3 (da) | 2006-03-27 |
| AU2001260540A1 (en) | 2001-12-11 |
| ES2253378T3 (es) | 2006-06-01 |
| ITRM20000293A1 (it) | 2001-11-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: UNIVERSITA CA'FOSCARI, VENICE, IT Owner name: CONSIGLIO NAZIONALE DELLE RICERCHE, ROM/ROMA, IT Owner name: ISTITUTO AGRARIO DI S. MICHELLE ALL'ADIGE, S. , IT |
|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: CONSIGLIO NAZIONALE DELLE RICERCHE, ROM/ROMA, IT Owner name: FONDAZIONE EDMUND MACH, SAN MICHELE ALL'ADIGE, IT Owner name: UNIVERSITA CA'FOSCARI, VENICE, IT |