DE60112957T2 - Sulfamide als gamma-secretase-inhibitoren - Google Patents

Sulfamide als gamma-secretase-inhibitoren Download PDF

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Publication number
DE60112957T2
DE60112957T2 DE60112957T DE60112957T DE60112957T2 DE 60112957 T2 DE60112957 T2 DE 60112957T2 DE 60112957 T DE60112957 T DE 60112957T DE 60112957 T DE60112957 T DE 60112957T DE 60112957 T2 DE60112957 T2 DE 60112957T2
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cor
amino
mhz
dcm
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DE60112957D1 (de
Inventor
James Ian COLLINS
Claire Joanne HANNAM
Timothy Harrison
John Stephen LEWIS
Andrew Madin
Jason Timothy SPAREY
John Brian WILLIAMS
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Organon Pharma UK Ltd
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Merck Sharp and Dohme Ltd
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Priority claimed from GB0026827A external-priority patent/GB0026827D0/en
Priority claimed from GB0122685A external-priority patent/GB0122685D0/en
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    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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AU2002210747B2 (en) 2006-06-01
ES2248397T3 (es) 2006-03-16
CA2427206C (en) 2011-06-28
EP1334085A1 (en) 2003-08-13
CA2427206A1 (en) 2002-05-10
AU1074702A (en) 2002-05-15
US20040049038A1 (en) 2004-03-11
WO2002036555A1 (en) 2002-05-10
DE60112957D1 (de) 2005-09-29
US7138400B2 (en) 2006-11-21
JP2006241163A (ja) 2006-09-14
JP3880051B2 (ja) 2007-02-14
EP1334085B1 (en) 2005-08-24

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