DE60110558D1 - Konjugate von gallensäure mit metallbindenden chelatverbdingungen und die verwendung davon - Google Patents
Konjugate von gallensäure mit metallbindenden chelatverbdingungen und die verwendung davonInfo
- Publication number
- DE60110558D1 DE60110558D1 DE60110558T DE60110558T DE60110558D1 DE 60110558 D1 DE60110558 D1 DE 60110558D1 DE 60110558 T DE60110558 T DE 60110558T DE 60110558 T DE60110558 T DE 60110558T DE 60110558 D1 DE60110558 D1 DE 60110558D1
- Authority
- DE
- Germany
- Prior art keywords
- gallen
- conditions
- metal binding
- acid conjugates
- chelate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI000383 | 2000-02-29 | ||
IT2000MI000383A IT1317862B1 (it) | 2000-02-29 | 2000-02-29 | Coniugati di acidi biliari con chelati complessi di ioni metallici eloro uso. |
PCT/EP2001/001971 WO2001064708A1 (en) | 2000-02-29 | 2001-02-21 | Bile acids conjugates with metal ion chelates and the use thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60110558D1 true DE60110558D1 (de) | 2005-06-09 |
DE60110558T2 DE60110558T2 (de) | 2005-09-22 |
Family
ID=11444243
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60110558T Expired - Lifetime DE60110558T2 (de) | 2000-02-29 | 2001-02-21 | Konjugate von gallensäure mit metallbindenden chelatverbdingungen und die verwendung davon |
Country Status (8)
Country | Link |
---|---|
US (1) | US6803030B2 (de) |
EP (1) | EP1259532B1 (de) |
JP (1) | JP5052726B2 (de) |
AT (1) | ATE294813T1 (de) |
AU (1) | AU4064401A (de) |
DE (1) | DE60110558T2 (de) |
IT (1) | IT1317862B1 (de) |
WO (1) | WO2001064708A1 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1318485B1 (it) | 2000-04-21 | 2003-08-25 | Bracco Spa | Uso di derivati di acidi biliari coniugati con complessi di ionimetallici nella visualizzazione diagnostica di sistemi microvascolari |
US6919333B2 (en) * | 2002-11-12 | 2005-07-19 | Rutgers, The State University Of New Jersey | Bis-transition-metal-chelate probes |
WO2003091689A2 (en) * | 2002-03-28 | 2003-11-06 | Rutgers, The State Of University Of New Jersey | Bis-transition-metal-chelate-probes |
US7611692B2 (en) * | 2003-01-13 | 2009-11-03 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
US7850947B2 (en) | 2003-01-13 | 2010-12-14 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
US7226577B2 (en) | 2003-01-13 | 2007-06-05 | Bracco Imaging, S. P. A. | Gastrin releasing peptide compounds |
US8420050B2 (en) * | 2003-01-13 | 2013-04-16 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
AU2003303714B2 (en) * | 2003-01-13 | 2009-02-19 | Bracco Imaging S.P.A. | Improved linkers for radiopharmaceutical compounds |
JP2008508333A (ja) * | 2004-08-05 | 2008-03-21 | ヨハン ウォルフガング ゲーテ−ウニベルジテート フランクフルト アム マイン | 標的分子の改変および組織化のための多価キレーター |
DE102004038134B4 (de) | 2004-08-05 | 2013-07-25 | Johann Wolfgang Goethe-Universität Frankfurt am Main | Multivalente Chelatoren zum Modifizieren und Organisieren von Zielmolekülen, Verfahren zu ihrer Herstellung sowie ihre Verwendung |
CA2596863A1 (en) * | 2005-02-03 | 2006-08-10 | Epix Pharmaceuticals, Inc. | Steady state perfusion methods |
EP2147684A1 (de) | 2008-07-22 | 2010-01-27 | Bracco Imaging S.p.A | Selektiv gegen Metallproteasen wirkende Diagnosemittel |
WO2014151411A1 (en) | 2013-03-15 | 2014-09-25 | Brigham Young University | Methods for treating inflammation, autoimmune disorders and pain |
US11524015B2 (en) | 2013-03-15 | 2022-12-13 | Brigham Young University | Methods for treating inflammation, autoimmune disorders and pain |
US11690855B2 (en) | 2013-10-17 | 2023-07-04 | Brigham Young University | Methods for treating lung infections and inflammation |
US20150203527A1 (en) | 2014-01-23 | 2015-07-23 | Brigham Young University | Cationic steroidal antimicrobials |
US10227376B2 (en) * | 2014-08-22 | 2019-03-12 | Brigham Young University | Radiolabeled cationic steroid antimicrobials and diagnostic methods |
EP3101012A1 (de) | 2015-06-04 | 2016-12-07 | Bayer Pharma Aktiengesellschaft | Neue gadoliniumchelat-verbindung zur verwendung in der magnetresonanzbildgebung |
US10226550B2 (en) | 2016-03-11 | 2019-03-12 | Brigham Young University | Cationic steroidal antimicrobial compositions for the treatment of dermal tissue |
ES2814555T3 (es) | 2016-11-28 | 2021-03-29 | Bayer Pharma AG | Compuestos de quelato de gadolinio con alta relaxividad para usar en la obtención de imágenes por resonancia magnética |
US10959433B2 (en) | 2017-03-21 | 2021-03-30 | Brigham Young University | Use of cationic steroidal antimicrobials for sporicidal activity |
AU2019382881A1 (en) | 2018-11-23 | 2021-05-20 | Bayer Aktiengesellschaft | Formulation of contrast media and process of preparation thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5057302A (en) * | 1987-02-13 | 1991-10-15 | Abbott Laboratories | Bifunctional chelating agents |
NO940115D0 (no) * | 1994-01-13 | 1994-01-13 | Nycomed Imaging As | Kontrastmidler for roentgen- og magnettomografisk avbildning |
GB9407812D0 (en) | 1994-04-20 | 1994-06-15 | Nycomed Salutar Inc | Compounds |
IT1269839B (it) * | 1994-05-26 | 1997-04-15 | Bracco Spa | Coniugati di acidi biliari, loro derivati con complessi metallici e relativi usi |
IT1283218B1 (it) | 1996-03-08 | 1998-04-16 | Bracco Spa | Polichelanti, loro complessi con ioni metallici, loro preparazione e loro usi |
IT1304501B1 (it) * | 1998-12-23 | 2001-03-19 | Bracco Spa | Uso di derivati di acidi biliari coniugati con complessi metallicicome "blood pool agents" per l'indagine diagnostica tramite risonanza |
-
2000
- 2000-02-29 IT IT2000MI000383A patent/IT1317862B1/it active
-
2001
- 2001-02-21 DE DE60110558T patent/DE60110558T2/de not_active Expired - Lifetime
- 2001-02-21 AU AU40644/01A patent/AU4064401A/en not_active Abandoned
- 2001-02-21 JP JP2001564201A patent/JP5052726B2/ja not_active Expired - Fee Related
- 2001-02-21 EP EP01911677A patent/EP1259532B1/de not_active Expired - Lifetime
- 2001-02-21 US US10/220,048 patent/US6803030B2/en not_active Expired - Fee Related
- 2001-02-21 AT AT01911677T patent/ATE294813T1/de not_active IP Right Cessation
- 2001-02-21 WO PCT/EP2001/001971 patent/WO2001064708A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
ITMI20000383A1 (it) | 2001-08-29 |
JP5052726B2 (ja) | 2012-10-17 |
JP2003525306A (ja) | 2003-08-26 |
ITMI20000383A0 (it) | 2000-02-29 |
EP1259532A1 (de) | 2002-11-27 |
US20030113265A1 (en) | 2003-06-19 |
DE60110558T2 (de) | 2005-09-22 |
EP1259532B1 (de) | 2005-05-04 |
AU4064401A (en) | 2001-09-12 |
IT1317862B1 (it) | 2003-07-15 |
US6803030B2 (en) | 2004-10-12 |
ATE294813T1 (de) | 2005-05-15 |
WO2001064708A1 (en) | 2001-09-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE60110558D1 (de) | Konjugate von gallensäure mit metallbindenden chelatverbdingungen und die verwendung davon | |
DE69431660T2 (de) | 2-pyridylmethylen-polyazamacrocyclophosphonsäuren, ihre komplexe und derivate zur verwendung als kontrastmittel | |
ATE285394T1 (de) | Phthalamid-lanthanid komplexe zur verwendung als lumineszenzmarker | |
NO20034637D0 (no) | NMR-logging i jordas magnetfelt | |
DE60141603D1 (de) | Neue mandelsäurederivate und deren verwendung als thrombininhibitoren | |
LV11429A (lv) | Triciklopoliazamakrociklofosfonskabes to kompleksi un atvasinajumi izmantosanai par kontrastvielam | |
DE50102815D1 (de) | Neue n-phenylpyrrolbisphosphanverbindungen und deren metallkomplexe | |
DE69822162D1 (de) | Neue tetrazolderivate | |
DE60136262D1 (de) | Lautsprecher und magnetischer schaltkreis zur verwendung für den lautsprecher | |
DK1195491T3 (da) | Låseindretning | |
NO307214B1 (no) | Makrosykliske chelanter, deres chelater og anvendelse derav innen det diagnostiske felt | |
DE60139222D1 (de) | Kornorientiertes Elektroblech mit ausgezeichneten magnetischen Eigenschaften | |
DE69810626T2 (de) | Strukturierung des Magnetismus magnetischer Medien | |
DE69016817T2 (de) | Magnetische Eisenoxidteilchen. | |
FR2868320B1 (fr) | Agent de contraste pour l'imagerie par resonance magnetique | |
ATE296665T1 (de) | Magnetspirale | |
BR0012675A (pt) | Uso de inibidores de il-18 | |
ITMI20031790A1 (it) | Antagonistici abiotici dell'eparina. | |
IT1298613B1 (it) | Chelati complessi di manganese ad alta relassivita' in siero | |
Nangia | The effects of exposure to electromagnetic fields similar to those produced by overhead powerlines upon DNA fragmentation | |
GB2408584B (en) | NMR logging in the earth's magnetic field | |
RU2000121124A (ru) | Применение аспирационной пыли электропечей литейного производства в качестве красящего вещества и пвх-композиция с ее использованием | |
DE29822899U1 (de) | Setzeisen für Stahlnägel mit magnetischem Halter |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |