DE60107803T2 - Neue antiarrythmische peptide - Google Patents
Neue antiarrythmische peptide Download PDFInfo
- Publication number
- DE60107803T2 DE60107803T2 DE60107803T DE60107803T DE60107803T2 DE 60107803 T2 DE60107803 T2 DE 60107803T2 DE 60107803 T DE60107803 T DE 60107803T DE 60107803 T DE60107803 T DE 60107803T DE 60107803 T2 DE60107803 T2 DE 60107803T2
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- Prior art keywords
- peptide
- gly
- cells
- compound
- resin
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- Expired - Lifetime
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Classifications
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
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- A—HUMAN NECESSITIES
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- C07K5/0823—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Pro-amino acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Reproductive Health (AREA)
- Emergency Medicine (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Hospice & Palliative Care (AREA)
- Dermatology (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK200000288 | 2000-02-23 | ||
| DKPA200000288 | 2000-02-23 | ||
| DK200000738 | 2000-05-04 | ||
| DKPA200000738 | 2000-05-04 | ||
| PCT/DK2001/000127 WO2001062775A2 (en) | 2000-02-23 | 2001-02-22 | Novel antiarrhythmic peptides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60107803D1 DE60107803D1 (de) | 2005-01-20 |
| DE60107803T2 true DE60107803T2 (de) | 2006-01-19 |
Family
ID=26068776
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60107803T Expired - Lifetime DE60107803T2 (de) | 2000-02-23 | 2001-02-22 | Neue antiarrythmische peptide |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1226160B1 (https=) |
| JP (1) | JP4327398B2 (https=) |
| AT (1) | ATE284896T1 (https=) |
| AU (1) | AU781674B2 (https=) |
| CA (1) | CA2385659C (https=) |
| DE (1) | DE60107803T2 (https=) |
| ES (1) | ES2228807T3 (https=) |
| PT (1) | PT1226160E (https=) |
| WO (1) | WO2001062775A2 (https=) |
| ZA (1) | ZA200306410B (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7250397B2 (en) | 2000-02-23 | 2007-07-31 | Zealand Pharma A/S | Antiarrhythmic peptides |
| US7585839B2 (en) | 2000-02-23 | 2009-09-08 | Zealand Pharma A/S | Medical uses of intercellular communication facilitating compounds |
| IL157447A0 (en) * | 2001-02-22 | 2004-03-28 | Zealand Pharma As Zealand Phar | New medical uses of intercellular communication facilitating compounds |
| CN1638790A (zh) | 2002-01-29 | 2005-07-13 | Wyeth公司 | 用于调节连接蛋白半通道的组合物和方法 |
| NZ540155A (en) * | 2002-11-25 | 2006-11-30 | Zealand Pharma As | Peptides that modulate gap junction intercellular communication (GJIC).for use in the treatment or prevention of pathologies associated with impaired GJIC |
| US7405210B2 (en) | 2003-05-21 | 2008-07-29 | Osi Pharmaceuticals, Inc. | Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase |
| JP2007527904A (ja) | 2004-03-08 | 2007-10-04 | プロシディオン・リミテッド | グリコーゲンホスホリラーゼ阻害剤としてのピロロピリジン−２−カルボン酸ヒドラジド化合物 |
| GB0514071D0 (en) | 2005-07-07 | 2005-08-17 | Zealand Pharma As | N- or C- terminally modified small peptides |
| UA96283C2 (uk) | 2005-12-23 | 2011-10-25 | Зіланд Фарма А/С | Модифіковані міметики лізину |
| PL2468724T3 (pl) | 2006-12-21 | 2016-05-31 | Zealand Pharma As | Synteza związków pirolidynowych |
| EP2260859A1 (en) | 2009-06-12 | 2010-12-15 | Zealand Pharma A/S | Compounds acting as peptide gap junction modulators and their uses |
| EP2900684A2 (en) | 2012-09-29 | 2015-08-05 | Novartis AG | Cyclic peptides and use as medicines |
| CN103113456B (zh) * | 2013-03-05 | 2014-07-16 | 中国药科大学 | 具有抗血小板聚集活性的僵蚕多肽及其制备方法和应用 |
| JP6989864B2 (ja) | 2017-05-05 | 2022-02-03 | ジーランド ファーマ，アー／エス | ギャップ結合細胞間コミュニケーションモジュレータ及び糖尿病性眼疾患の治療のためのそれらの使用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6259296A (ja) * | 1985-09-10 | 1987-03-14 | Green Cross Corp:The | ペプタイド誘導体 |
| DE19500990A1 (de) * | 1995-01-14 | 1996-07-18 | Stefan Dr Med Dhein | Neues Peptid, seine Herstellung und Verwendung |
| DE19707854A1 (de) * | 1997-02-27 | 1998-09-03 | Dhein Stefan Priv Doz Dr Med | Neue Cyclopeptide, deren Herstellung und Verwendung |
-
2001
- 2001-02-22 WO PCT/DK2001/000127 patent/WO2001062775A2/en not_active Ceased
- 2001-02-22 DE DE60107803T patent/DE60107803T2/de not_active Expired - Lifetime
- 2001-02-22 JP JP2001562556A patent/JP4327398B2/ja not_active Expired - Fee Related
- 2001-02-22 ES ES01907393T patent/ES2228807T3/es not_active Expired - Lifetime
- 2001-02-22 AT AT01907393T patent/ATE284896T1/de active
- 2001-02-22 CA CA2385659A patent/CA2385659C/en not_active Expired - Fee Related
- 2001-02-22 EP EP01907393A patent/EP1226160B1/en not_active Expired - Lifetime
- 2001-02-22 PT PT01907393T patent/PT1226160E/pt unknown
- 2001-02-22 AU AU35362/01A patent/AU781674B2/en not_active Ceased
-
2003
- 2003-08-18 ZA ZA200306410A patent/ZA200306410B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001062775A2 (en) | 2001-08-30 |
| EP1226160B1 (en) | 2004-12-15 |
| DE60107803D1 (de) | 2005-01-20 |
| JP4327398B2 (ja) | 2009-09-09 |
| CA2385659C (en) | 2011-04-19 |
| AU3536201A (en) | 2001-09-03 |
| AU781674B2 (en) | 2005-06-02 |
| WO2001062775A3 (en) | 2002-01-31 |
| JP2003528826A (ja) | 2003-09-30 |
| PT1226160E (pt) | 2005-04-29 |
| ZA200306410B (en) | 2007-05-30 |
| CA2385659A1 (en) | 2001-08-30 |
| ES2228807T3 (es) | 2005-04-16 |
| EP1226160A2 (en) | 2002-07-31 |
| ATE284896T1 (de) | 2005-01-15 |
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