DE60041655D1 - Auslösender rezeptor der an der natürlichen cytotoxizität der menschlichen natürlichen killerzellen (natural killer cells) beteiligt ist und antikörper die diesen rezeptor identifizieren - Google Patents
Auslösender rezeptor der an der natürlichen cytotoxizität der menschlichen natürlichen killerzellen (natural killer cells) beteiligt ist und antikörper die diesen rezeptor identifizierenInfo
- Publication number
- DE60041655D1 DE60041655D1 DE60041655T DE60041655T DE60041655D1 DE 60041655 D1 DE60041655 D1 DE 60041655D1 DE 60041655 T DE60041655 T DE 60041655T DE 60041655 T DE60041655 T DE 60041655T DE 60041655 D1 DE60041655 D1 DE 60041655D1
- Authority
- DE
- Germany
- Prior art keywords
- receptor
- natural
- killer cells
- involved
- cytotoxicity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000003013 cytotoxicity Effects 0.000 title abstract 2
- 231100000135 cytotoxicity Toxicity 0.000 title abstract 2
- 210000000822 natural killer cell Anatomy 0.000 title 1
- 108010004222 Natural Cytotoxicity Triggering Receptor 3 Proteins 0.000 abstract 2
- 102100032852 Natural cytotoxicity triggering receptor 3 Human genes 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 210000001939 mature NK cell Anatomy 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Zoology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Virology (AREA)
- Transplantation (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44051499A | 1999-11-15 | 1999-11-15 | |
CA2288307A CA2288307C (en) | 1999-11-15 | 1999-11-15 | Novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cells and antibodies that identify the same |
PCT/EP2000/011697 WO2001036630A2 (en) | 1999-11-15 | 2000-11-15 | Triggering receptor involved in natural cytotoxicity mediated by human natural killer cells, and antibodies that identify the same |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60041655D1 true DE60041655D1 (de) | 2009-04-09 |
Family
ID=25681295
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60041655T Expired - Lifetime DE60041655D1 (de) | 1999-11-15 | 2000-11-15 | Auslösender rezeptor der an der natürlichen cytotoxizität der menschlichen natürlichen killerzellen (natural killer cells) beteiligt ist und antikörper die diesen rezeptor identifizieren |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1240326B1 (de) |
JP (1) | JP4776845B2 (de) |
AT (1) | ATE423848T1 (de) |
AU (1) | AU783899B2 (de) |
DE (1) | DE60041655D1 (de) |
DK (1) | DK1240326T3 (de) |
ES (1) | ES2321687T3 (de) |
WO (1) | WO2001036630A2 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10261223A1 (de) * | 2002-12-20 | 2004-07-08 | MedInnova Gesellschaft für medizinische Innovationen aus akademischer Forschung mbH | Steigerung der Immunantwort durch Substanzen, welche die Funktion von Natürlichen Killerzellen beeinflussen |
AU2003294930B2 (en) * | 2002-12-23 | 2008-12-04 | Innate Pharma | Pharmaceutical compositions having an effect on the proliferation of NK cells and a method using the same |
EP1445614A1 (de) * | 2003-02-06 | 2004-08-11 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Verfahren zur in vitro Überwachung der Entwicklung von HIV Virus eines Individuums |
KR20060038461A (ko) | 2003-07-24 | 2006-05-03 | 이나뜨 파르마 | Nk 세포 강화 화합물을 사용하여 치료용 항체의 효율을높이는 방법 및 조성물 |
AU2005238298A1 (en) * | 2004-04-30 | 2005-11-10 | Innate Pharma | Compositions and methods for enhancing NK cell activity |
ZA200610134B (en) * | 2004-06-18 | 2008-06-25 | Genentech Inc | Use of Apo2L receptor agonists and NK cells or NK cell activators |
CA2575607C (en) | 2004-08-03 | 2017-07-11 | Innate Pharma | Therapeutic and diagnostic methods and compositions targeting 4ig-b7-h3 and its counterpart nk cell receptor |
EP1626059A1 (de) * | 2004-08-09 | 2006-02-15 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Angiogenische und immunologische Verwendungen von anti-CD160 spezifischen Stoffen, erhältlich vom monoklonalen Antiköper CL1-R2 |
EP1831258B2 (de) | 2004-12-28 | 2023-06-07 | Innate Pharma S.A. | Monoklonale antikörper gegen nkg2a |
WO2007042573A2 (en) | 2005-10-14 | 2007-04-19 | Innate Pharma | Compositions and methods for treating proliferative disorders |
ES2629440T5 (es) * | 2007-10-04 | 2020-11-20 | Zymogenetics Inc | zB7H6 miembro de la familia B7 y composiciones y métodos relacionados |
EP3325967B1 (de) * | 2015-07-24 | 2019-12-04 | Innate Pharma | Methoden zur detektion von gewebe-infiltrierenden nk zellen. |
EP3713959A1 (de) | 2017-11-21 | 2020-09-30 | Innate Pharma | Multispezifische antigenbindende proteine |
WO2023110937A1 (en) | 2021-12-14 | 2023-06-22 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Depletion of nk cells for the treatment of adverse post-ischemic cardiac remodeling |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09502089A (ja) * | 1993-08-27 | 1997-03-04 | ダナ−ファーバー キャンサー インスティチュート インコーポレイテッド | ナチュラルキラー細胞特異性抗原およびこの抗原を識別する抗体 |
ZA9810133B (en) * | 1997-11-07 | 1999-05-17 | Biogen Inc | BMOG a novel protein member of the myelin-oligodendrocyte glycoprotein family and its use for ummonomodulatory purposes |
JP4832640B2 (ja) * | 1998-03-27 | 2011-12-07 | ガブリエル ミュルソフ | Hsp70タンパク質の新規使用 |
-
2000
- 2000-11-15 AU AU26677/01A patent/AU783899B2/en not_active Ceased
- 2000-11-15 AT AT00989877T patent/ATE423848T1/de active
- 2000-11-15 ES ES00989877T patent/ES2321687T3/es not_active Expired - Lifetime
- 2000-11-15 JP JP2001538509A patent/JP4776845B2/ja not_active Expired - Fee Related
- 2000-11-15 DK DK00989877T patent/DK1240326T3/da active
- 2000-11-15 WO PCT/EP2000/011697 patent/WO2001036630A2/en active IP Right Grant
- 2000-11-15 EP EP00989877A patent/EP1240326B1/de not_active Expired - Lifetime
- 2000-11-15 DE DE60041655T patent/DE60041655D1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ES2321687T3 (es) | 2009-06-10 |
JP2003523735A (ja) | 2003-08-12 |
AU2667701A (en) | 2001-05-30 |
WO2001036630A3 (en) | 2001-11-08 |
EP1240326B1 (de) | 2009-02-25 |
EP1240326A2 (de) | 2002-09-18 |
WO2001036630A9 (en) | 2002-09-19 |
ATE423848T1 (de) | 2009-03-15 |
DK1240326T3 (da) | 2009-06-02 |
WO2001036630A2 (en) | 2001-05-25 |
JP4776845B2 (ja) | 2011-09-21 |
AU783899B2 (en) | 2005-12-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |