DE60039120D1 - Katalytische rnas mit aminoacylierender aktivität - Google Patents

Katalytische rnas mit aminoacylierender aktivität

Info

Publication number
DE60039120D1
DE60039120D1 DE60039120T DE60039120T DE60039120D1 DE 60039120 D1 DE60039120 D1 DE 60039120D1 DE 60039120 T DE60039120 T DE 60039120T DE 60039120 T DE60039120 T DE 60039120T DE 60039120 D1 DE60039120 D1 DE 60039120D1
Authority
DE
Germany
Prior art keywords
molecules
catalytic
activity
catalytic rnas
aminoacylation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60039120T
Other languages
English (en)
Inventor
Suga Hiroaki
Kourouklis Dimitrios
Hirohide Saito
Nick Lee
Neil Bonzagni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Foundation of State University of New York
Original Assignee
Research Foundation of State University of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Foundation of State University of New York filed Critical Research Foundation of State University of New York
Application granted granted Critical
Publication of DE60039120D1 publication Critical patent/DE60039120D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes

Landscapes

  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
DE60039120T 1999-11-24 2000-11-22 Katalytische rnas mit aminoacylierender aktivität Expired - Lifetime DE60039120D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16733199P 1999-11-24 1999-11-24
US21438200P 2000-06-28 2000-06-28
PCT/US2000/032184 WO2001038582A1 (en) 1999-11-24 2000-11-22 CATALYTIC RNAs WITH AMINOACYLATION ACTIVITY

Publications (1)

Publication Number Publication Date
DE60039120D1 true DE60039120D1 (de) 2008-07-17

Family

ID=26863053

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60039120T Expired - Lifetime DE60039120D1 (de) 1999-11-24 2000-11-22 Katalytische rnas mit aminoacylierender aktivität

Country Status (8)

Country Link
US (1) US7001723B1 (de)
EP (1) EP1232285B1 (de)
JP (1) JP4745577B2 (de)
AT (1) ATE397672T1 (de)
AU (1) AU1927601A (de)
CA (1) CA2391433C (de)
DE (1) DE60039120D1 (de)
WO (1) WO2001038582A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE437946T1 (de) * 2002-02-15 2009-08-15 Univ New York State Res Found Ribozyme mit breiter trna-aminoacylierungswirkung
EP1964916B1 (de) * 2005-12-06 2012-08-01 The University of Tokyo Mehrzweck-Acylierungskatalysator und Verwendung davon
JP5200241B2 (ja) 2006-11-17 2013-06-05 国立大学法人 東京大学 Ｎ末端に非天然骨格をもつポリペプチドの翻訳合成とその応用
WO2008117833A1 (ja) 2007-03-26 2008-10-02 The University Of Tokyo 環状ペプチド化合物の合成方法
EP2647704B1 (de) 2010-12-01 2017-11-01 Mitsubishi Tanabe Pharma Corporation Polynukleotidkonstrukt zur präsentation von fab in einem zellulären übersetzungssystem sowie verfahren zur herstellung und zum screening von fab damit
JP5948673B2 (ja) 2011-03-10 2016-07-06 ジーンフロンティア株式会社 リポ多糖混入量を低減した蛋白質合成用組成物、該組成物を用いた蛋白質製造方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639595A (en) * 1990-05-01 1997-06-17 Isis Phamaceuticals, Inc. Identification of novel drugs and reagents
US5270163A (en) 1990-06-11 1993-12-14 University Research Corporation Methods for identifying nucleic acid ligands
ES2110444T3 (es) 1990-06-11 1998-02-16 Nexstar Pharmaceuticals Inc Ligandos de acidos nucleicos.
US5998142A (en) 1993-09-08 1999-12-07 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: chemi-SELEX
US6063566A (en) 1994-05-13 2000-05-16 The Scripps Research Institute Catalytic RNA molecules
ES2127106B1 (es) 1996-03-21 1999-11-16 Menarini Lab Derivados benzopiranicos con accion antagonista de los leucotrienos, procedimiento para su preparacion y utilizacion de los mismos.
US5792613A (en) * 1996-06-12 1998-08-11 The Curators Of The University Of Missouri Method for obtaining RNA aptamers based on shape selection
US5871924A (en) * 1997-01-27 1999-02-16 Nexstar Pharmaceuticals, Inc. Method for the production of ligands capable of facilitating aminoacyl-RNA synthesis
DE19801153A1 (de) 1998-01-14 1999-07-15 Jenne Andreas Verfahren zur Selektion von Ribozymen, die Ribonucleinsäuren in trans an 2'-OH-Gruppen kovalent modifizieren können und durch dieses Verfahren erhältliche Ribozyme

Also Published As

Publication number Publication date
EP1232285B1 (de) 2008-06-04
AU1927601A (en) 2001-06-04
CA2391433C (en) 2011-02-08
JP4745577B2 (ja) 2011-08-10
JP2003514572A (ja) 2003-04-22
EP1232285A4 (de) 2005-01-12
ATE397672T1 (de) 2008-06-15
US7001723B1 (en) 2006-02-21
EP1232285A1 (de) 2002-08-21
CA2391433A1 (en) 2001-05-31
WO2001038582A1 (en) 2001-05-31

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Legal Events

Date Code Title Description
8381 Inventor (new situation)

Inventor name: SUGA, HIROAKI, WILLIAMSVILLE, N.Y., US

Inventor name: KOUROUKLIS, DIMITRIOS, WILLIAMSVILLE, N.Y., US

Inventor name: SAITO, HIROHIDE, TOKYO, 168-0073, JP

Inventor name: LEE, NICK, MINNEAPOLIS, MN 55414, US

Inventor name: BONZAGNI, NEIL, BUFFALO, NY 14261, US

8381 Inventor (new situation)

Inventor name: SUGA, HIROAKI, WILLIAMSVILLE, N.Y., US

Inventor name: KOUROUKLIS, DIMITROS, WILLIAMSVILLE, N.Y., US

Inventor name: SAITO, HIROHIDE, TOKYO, 168-0073, JP

Inventor name: LEE, NICK, MINNEAPOLIS, MN 55414, US

Inventor name: BONZAGNI, NEIL, BUFFALO, NY 14261, US

8364 No opposition during term of opposition