DE60039062D1 - Fluorimeter mit lichtquelle mit geringer wärmeerzeugung - Google Patents
Fluorimeter mit lichtquelle mit geringer wärmeerzeugungInfo
- Publication number
- DE60039062D1 DE60039062D1 DE60039062T DE60039062T DE60039062D1 DE 60039062 D1 DE60039062 D1 DE 60039062D1 DE 60039062 T DE60039062 T DE 60039062T DE 60039062 T DE60039062 T DE 60039062T DE 60039062 D1 DE60039062 D1 DE 60039062D1
- Authority
- DE
- Germany
- Prior art keywords
- fluorimeter
- light source
- heat generation
- low heat
- low
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0654—Lenses; Optical fibres
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6463—Optics
- G01N2021/6478—Special lenses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6482—Sample cells, cuvettes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Optics & Photonics (AREA)
- Molecular Biology (AREA)
- Clinical Laboratory Science (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16526799P | 1999-11-12 | 1999-11-12 | |
PCT/US2000/030771 WO2001035079A1 (en) | 1999-11-12 | 2000-11-09 | Fluorometer with low heat-generating light source |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60039062D1 true DE60039062D1 (de) | 2008-07-10 |
Family
ID=22598180
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60039062T Expired - Lifetime DE60039062D1 (de) | 1999-11-12 | 2000-11-09 | Fluorimeter mit lichtquelle mit geringer wärmeerzeugung |
Country Status (5)
Country | Link |
---|---|
EP (2) | EP2264439A3 (de) |
JP (1) | JP4846152B2 (de) |
AU (1) | AU1655901A (de) |
DE (1) | DE60039062D1 (de) |
WO (1) | WO2001035079A1 (de) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1664562A (zh) | 1998-05-16 | 2005-09-07 | 阿普尔拉公司 | 用于监测dna聚合酶链反应的仪器 |
US6818437B1 (en) | 1998-05-16 | 2004-11-16 | Applera Corporation | Instrument for monitoring polymerase chain reaction of DNA |
US7498164B2 (en) | 1998-05-16 | 2009-03-03 | Applied Biosystems, Llc | Instrument for monitoring nucleic acid sequence amplification reaction |
US7387891B2 (en) | 1999-05-17 | 2008-06-17 | Applera Corporation | Optical instrument including excitation source |
US7423750B2 (en) | 2001-11-29 | 2008-09-09 | Applera Corporation | Configurations, systems, and methods for optical scanning with at least one first relative angular motion and at least one second angular motion or at least one linear motion |
US7410793B2 (en) | 1999-05-17 | 2008-08-12 | Applera Corporation | Optical instrument including excitation source |
US20050279949A1 (en) | 1999-05-17 | 2005-12-22 | Applera Corporation | Temperature control for light-emitting diode stabilization |
US6563581B1 (en) | 2000-07-14 | 2003-05-13 | Applera Corporation | Scanning system and method for scanning a plurality of samples |
AT410375B (de) * | 2001-05-23 | 2003-04-25 | Anthos Labtec Instr Gmbh | Fluorometer |
WO2003002959A1 (en) | 2001-06-15 | 2003-01-09 | Mj Research, Inc. | Controller for a fluorometer |
DE10131687A1 (de) * | 2001-06-29 | 2003-01-16 | Eppendorf Ag | Vorrichtung zur Durchführung von Nukleinsäure-Amplifikationsreaktionen bei gleichzeitiger Verfolgung der Bildung von Amplifikationsprodukten |
US7635588B2 (en) | 2001-11-29 | 2009-12-22 | Applied Biosystems, Llc | Apparatus and method for differentiating multiple fluorescence signals by excitation wavelength |
US6982166B2 (en) | 2002-05-16 | 2006-01-03 | Applera Corporation | Lens assembly for biological testing |
US9157860B2 (en) | 2002-05-16 | 2015-10-13 | Applied Biosystems, Llc | Achromatic lens array |
EP2463644B1 (de) | 2002-05-17 | 2013-10-09 | Life Technologies Corporation | Optisches Instrument mit Anregungsquelle |
EP1506390B1 (de) | 2002-05-17 | 2011-12-14 | Life Technologies Corporation | Vorrichtung und verfahren zur unterscheidung mehrerer fluoreszenzsignale anhand ihrer anregungswellenlänge |
US7083974B2 (en) | 2002-07-12 | 2006-08-01 | Applera Corporation | Rotatable sample disk and method of loading a sample disk |
US7452712B2 (en) | 2002-07-30 | 2008-11-18 | Applied Biosystems Inc. | Sample block apparatus and method of maintaining a microcard on a sample block |
GB0229409D0 (en) * | 2002-12-17 | 2003-01-22 | Molecular Sensing Plc | Assay apparatus |
US7682565B2 (en) | 2002-12-20 | 2010-03-23 | Biotrove, Inc. | Assay apparatus and method using microfluidic arrays |
GB2399776A (en) * | 2003-03-24 | 2004-09-29 | Pa Knowledge Ltd | Cyclical heating and cooling device and associated methods |
US7148043B2 (en) | 2003-05-08 | 2006-12-12 | Bio-Rad Laboratories, Inc. | Systems and methods for fluorescence detection with a movable detection module |
JP2007504445A (ja) * | 2003-08-26 | 2007-03-01 | ブルーシフト・バイオテクノロジーズ・インコーポレーテッド | 時間依存蛍光計測 |
US7570443B2 (en) | 2003-09-19 | 2009-08-04 | Applied Biosystems, Llc | Optical camera alignment |
US7113285B2 (en) | 2003-12-09 | 2006-09-26 | Beckman Coulter, Inc. | Multimode reader |
US7295316B2 (en) * | 2004-01-14 | 2007-11-13 | Applera Corporation | Fluorescent detector with automatic changing filters |
DE102005027555B3 (de) * | 2005-06-14 | 2006-10-05 | Eppendorf Ag | Thermocycler |
JP2007046904A (ja) * | 2005-08-05 | 2007-02-22 | Sanyo Electric Co Ltd | 反応検出装置 |
DE102005043834A1 (de) * | 2005-09-13 | 2007-03-22 | Eppendorf Ag | Vorrichtung zur Durchführung von Real-Time PCR-Reaktionen |
DE102005046583A1 (de) * | 2005-09-28 | 2007-03-29 | Eppendorf Ag | Laborvorrichtung zur gleichzeitigen Durchführung von Reaktionen in einer Mehrzahl von Proben |
US8232091B2 (en) | 2006-05-17 | 2012-07-31 | California Institute Of Technology | Thermal cycling system |
DE102006048346A1 (de) | 2006-10-12 | 2008-04-17 | Eppendorf Ag | Verfahren zur Vorrichtung zur quantitativen Echtzeitanalyse von fluoreszierenden Proben |
DE102006056596A1 (de) * | 2006-11-30 | 2008-06-05 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Vorrichtung zum ortstaufgelösten Detektieren von Fluoreszenzsignalen |
US9475051B2 (en) | 2007-02-27 | 2016-10-25 | Sony Corporation | Nucleic acid amplifier |
JP4458133B2 (ja) * | 2007-02-27 | 2010-04-28 | ソニー株式会社 | 核酸増幅装置 |
CN101821609A (zh) | 2007-08-29 | 2010-09-01 | 艾本德股份有限公司 | 用于多个样品的辐射度测量的设备和方法 |
DE202010010523U1 (de) | 2009-09-09 | 2010-11-18 | Helixis, Inc., Carlsbad | Optisches System für Mehrfachreaktionen |
IN2014DN03441A (de) | 2011-09-30 | 2015-06-05 | Life Technologies Corp | |
EP2581728B1 (de) * | 2011-10-10 | 2013-09-18 | CYCLERtest B.V. | Kalibrierungsvorrichtung für einen Thermocycler |
GB2500177A (en) * | 2012-03-07 | 2013-09-18 | Valeport Ltd | Fluorometer with beamsplitter |
JP2014071083A (ja) * | 2012-10-01 | 2014-04-21 | Ushio Inc | 蛍光光度計 |
SG11201506481QA (en) | 2013-02-22 | 2015-09-29 | Life Technologies Corp | Optical systems and methods for biological analysis |
GB201321609D0 (en) | 2013-12-06 | 2014-01-22 | Starna Scient Ltd | PCR Validation Tubes |
US9261459B1 (en) * | 2014-08-12 | 2016-02-16 | Ecolab Usa Inc. | Handheld fluorometer |
EP3254085B1 (de) | 2015-02-06 | 2020-04-29 | Life Technologies Corporation | Ein instrument zur biologischen analyse |
EP3299312B1 (de) | 2016-09-21 | 2019-03-13 | Mondi AG | Kunststoffgewebeverbund, verpackungsbeutel aus einem kunststoffgewebeverbund sowie verfahren zur herstellung eines kunststoffgewebeverbundes |
DE102021133081B3 (de) | 2021-12-14 | 2023-05-04 | Bmg Labtech Gmbh | Mikroplatten-Lesegerät und Verfahren zum Durchführen von optischen Messungen mit einem Mikroplatten-Lesegerät |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5333675C1 (en) | 1986-02-25 | 2001-05-01 | Perkin Elmer Corp | Apparatus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps |
US5038852A (en) | 1986-02-25 | 1991-08-13 | Cetus Corporation | Apparatus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
JP2779824B2 (ja) * | 1989-02-09 | 1998-07-23 | スズキ株式会社 | 免疫学的凝集反応検出装置 |
US5073029A (en) * | 1990-02-16 | 1991-12-17 | Eqm Research, Inc. | Multisource device for photometric analysis and associated chromogens |
KR100236506B1 (ko) | 1990-11-29 | 2000-01-15 | 퍼킨-엘머시터스인스트루먼츠 | 폴리머라제 연쇄 반응 수행 장치 |
US5243540A (en) * | 1991-04-03 | 1993-09-07 | The United States Of America As Represented By The Secretary Of The Army | Computer-driven amino acid indexer for peptide synthesis |
JPH07120393A (ja) * | 1993-10-13 | 1995-05-12 | Nippon Tectron Co Ltd | 蛍光検出法 |
WO1995030139A1 (en) * | 1994-04-29 | 1995-11-09 | Perkin-Elmer Corporation | System for real time detection of nucleic acid amplification products |
JPH09264844A (ja) * | 1996-03-28 | 1997-10-07 | Tokimec Inc | 吸光光度計 |
US6084683A (en) * | 1996-05-28 | 2000-07-04 | Bruno; Alfredo Emilio | Optical detection apparatus for chemical analyses of small volumes of samples |
ATE390491T1 (de) * | 1996-06-04 | 2008-04-15 | Univ Utah Res Found | Behälter zum durchführen und beobachten biologischer prozesse |
US5854684A (en) * | 1996-09-26 | 1998-12-29 | Sarnoff Corporation | Massively parallel detection |
DE19651667C2 (de) * | 1996-12-12 | 2003-07-03 | Rudolf Groskopf | Vorrichtung zur dreidimensionalen Untersuchung eines Objektes |
US5894351A (en) * | 1997-05-13 | 1999-04-13 | Colvin, Jr.; Arthur E. | Fluorescence sensing device |
US6043880A (en) * | 1997-09-15 | 2000-03-28 | Becton Dickinson And Company | Automated optical reader for nucleic acid assays |
-
2000
- 2000-11-09 JP JP2001536560A patent/JP4846152B2/ja not_active Expired - Fee Related
- 2000-11-09 WO PCT/US2000/030771 patent/WO2001035079A1/en active Application Filing
- 2000-11-09 EP EP10012856A patent/EP2264439A3/de not_active Withdrawn
- 2000-11-09 AU AU16559/01A patent/AU1655901A/en not_active Abandoned
- 2000-11-09 DE DE60039062T patent/DE60039062D1/de not_active Expired - Lifetime
- 2000-11-09 EP EP00979148A patent/EP1228357B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP2003514223A (ja) | 2003-04-15 |
JP4846152B2 (ja) | 2011-12-28 |
WO2001035079A1 (en) | 2001-05-17 |
AU1655901A (en) | 2001-06-06 |
EP1228357A1 (de) | 2002-08-07 |
EP2264439A2 (de) | 2010-12-22 |
EP2264439A3 (de) | 2011-01-19 |
EP1228357B1 (de) | 2008-05-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |