DE60031100D1 - Hapten modifizierte tumorzellen und verfahren zur herstellung und deren verwendung - Google Patents

Hapten modifizierte tumorzellen und verfahren zur herstellung und deren verwendung

Info

Publication number
DE60031100D1
DE60031100D1 DE60031100T DE60031100T DE60031100D1 DE 60031100 D1 DE60031100 D1 DE 60031100D1 DE 60031100 T DE60031100 T DE 60031100T DE 60031100 T DE60031100 T DE 60031100T DE 60031100 D1 DE60031100 D1 DE 60031100D1
Authority
DE
Germany
Prior art keywords
preparation
tumor cells
modified tumor
hapten modified
hapten
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60031100T
Other languages
English (en)
Other versions
DE60031100T2 (de
Inventor
David Berd
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thomas Jefferson University
Original Assignee
Thomas Jefferson University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomas Jefferson University filed Critical Thomas Jefferson University
Publication of DE60031100D1 publication Critical patent/DE60031100D1/de
Application granted granted Critical
Publication of DE60031100T2 publication Critical patent/DE60031100T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5152—Tumor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6012—Haptens, e.g. di- or trinitrophenyl (DNP, TNP)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE60031100T 1999-03-16 2000-03-15 Hapten modifizierte tumorzellen und verfahren zur herstellung und deren verwendung Expired - Fee Related DE60031100T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12467299P 1999-03-16 1999-03-16
US124672P 1999-03-16
PCT/US2000/006785 WO2000057911A2 (en) 1999-03-16 2000-03-15 Hapten-conjugated mammalian cells and methods of making and using thereof

Publications (2)

Publication Number Publication Date
DE60031100D1 true DE60031100D1 (de) 2006-11-16
DE60031100T2 DE60031100T2 (de) 2007-03-08

Family

ID=22416199

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60031100T Expired - Fee Related DE60031100T2 (de) 1999-03-16 2000-03-15 Hapten modifizierte tumorzellen und verfahren zur herstellung und deren verwendung

Country Status (9)

Country Link
US (1) US6403104B1 (de)
EP (2) EP1723963A3 (de)
AR (1) AR022937A1 (de)
AT (1) ATE341338T1 (de)
AU (1) AU757980B2 (de)
CA (1) CA2367922A1 (de)
DE (1) DE60031100T2 (de)
ES (1) ES2273680T3 (de)
WO (1) WO2000057911A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1723963A3 (de) * 1999-03-16 2008-05-07 Thomas Jefferson University Hapten Modifizierte Tumorzellen
US7297330B2 (en) * 2000-02-04 2007-11-20 Thomas Jefferson University Low dose haptenized tumor cell and tumor cell extract immunotherapy
CA2474960A1 (en) * 2002-02-01 2003-08-07 Thomas Jefferson University Mixed haptenized tumor cells and extracts and methods of treating or screening for cancer
CA2489076A1 (en) * 2002-06-10 2003-12-18 Avax Technologies Inc. Cryopreservation of haptenized tumor cells
US7674456B2 (en) * 2004-06-14 2010-03-09 Charles Wiseman Breast cancer cell lines and uses thereof
US8257715B1 (en) 2004-08-26 2012-09-04 University Of Notre Dame Tissue vaccines and uses thereof
US20060240047A1 (en) * 2005-01-14 2006-10-26 Avax Technologies, Inc. Method for producing a vaccine for the treatment of cancer
US9308252B2 (en) * 2005-10-27 2016-04-12 Cook Biotech, Inc. Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins
US8802113B2 (en) * 2005-10-27 2014-08-12 University Of Notre Dame Extracellular matrix cancer vaccine adjuvant
US8778362B2 (en) 2005-10-27 2014-07-15 University Of Notre Dame Anti-tumor/cancer heterologous acellular collagenous preparations and uses thereof
US8778360B2 (en) * 2005-10-27 2014-07-15 University Of Notre Dame Extracellular matrix cancer vaccine adjuvant
US9283266B2 (en) * 2008-02-28 2016-03-15 University Of Notre Dame Metastasis inhibition preparations and methods
US8846059B2 (en) 2009-12-08 2014-09-30 University Of Notre Dame Extracellular matrix adjuvant and methods for prevention and/or inhibition of ovarian tumors and ovarian cancer
US20110150934A1 (en) * 2009-12-18 2011-06-23 University Of Notre Dame Ovarian Tumor Tissue Cell Preparations/Vaccines for the Treatment/Inhibition of Ovarian Tumors and Ovarian Cancer
CA2899901A1 (en) * 2013-02-01 2014-08-07 University Of Iowa Research Foundation Tumor vaccines and methods of use thereof
US20210100896A1 (en) * 2017-04-05 2021-04-08 University Of Miami Methods and compositions for stimulating the immune system

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5290557A (en) 1992-07-16 1994-03-01 W. Neudorff Gmbh Kg Saponin containing anti-feedant and molluscicide for terrestrial mollusc control
BR9609026A (pt) * 1995-06-07 1999-07-06 Univ Jefferson Composição processo para o tratamento do cáncer e de detecção para a produção de citicina por tumores para determinar a eficácia de um autólogo e kit diagnóstico para detecção para eficácia de compostos celulares autólogos
EP0871480A4 (de) 1996-10-04 2001-04-04 Univ Jefferson T-zellen zur vermittlung einer immunantwort und anwendungsverfahren
JP2003524583A (ja) 1998-04-09 2003-08-19 トーマス・ジェファーソン・ユニバーシティ 黒色腫患者における肺転移に対して抗腫瘍応答を誘導する方法
EP1723963A3 (de) * 1999-03-16 2008-05-07 Thomas Jefferson University Hapten Modifizierte Tumorzellen

Also Published As

Publication number Publication date
ATE341338T1 (de) 2006-10-15
WO2000057911A3 (en) 2001-01-18
CA2367922A1 (en) 2000-10-05
US6403104B1 (en) 2002-06-11
EP1723963A2 (de) 2006-11-22
WO2000057911A2 (en) 2000-10-05
AU4010600A (en) 2000-10-16
AR022937A1 (es) 2002-09-04
AU757980B2 (en) 2003-03-13
EP1723963A3 (de) 2008-05-07
EP1162996A2 (de) 2001-12-19
ES2273680T3 (es) 2007-05-16
DE60031100T2 (de) 2007-03-08
EP1162996B1 (de) 2006-10-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee