DE60031096D1 - Auf der dreidimensionalen struktur von lta4 hydrolase basierender entwurf von arzneimitteln - Google Patents
Auf der dreidimensionalen struktur von lta4 hydrolase basierender entwurf von arzneimittelnInfo
- Publication number
- DE60031096D1 DE60031096D1 DE60031096T DE60031096T DE60031096D1 DE 60031096 D1 DE60031096 D1 DE 60031096D1 DE 60031096 T DE60031096 T DE 60031096T DE 60031096 T DE60031096 T DE 60031096T DE 60031096 D1 DE60031096 D1 DE 60031096D1
- Authority
- DE
- Germany
- Prior art keywords
- lta4
- hydrolase
- dimensional structure
- present
- lta4 hydrolase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12211099P | 1999-02-26 | 1999-02-26 | |
SE9900722 | 1999-02-26 | ||
US122110P | 1999-02-26 | ||
SE9900722A SE9900722D0 (sv) | 1999-02-26 | 1999-02-26 | Drug design based on the structure of LTA4 hydrolase |
PCT/SE2000/000384 WO2000050577A1 (en) | 1999-02-26 | 2000-02-28 | Drug design based on the structure of lta4 hydrolase |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60031096D1 true DE60031096D1 (de) | 2006-11-16 |
DE60031096T2 DE60031096T2 (de) | 2007-05-10 |
Family
ID=26663520
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60031096T Expired - Lifetime DE60031096T2 (de) | 1999-02-26 | 2000-02-28 | Auf der dreidimensionalen struktur von lta4 hydrolase basierender entwurf von arzneimitteln |
Country Status (6)
Country | Link |
---|---|
US (1) | US7590494B1 (de) |
EP (1) | EP1157101B1 (de) |
AT (1) | ATE341615T1 (de) |
AU (1) | AU3468300A (de) |
DE (1) | DE60031096T2 (de) |
WO (1) | WO2000050577A1 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7851486B2 (en) | 2002-10-17 | 2010-12-14 | Decode Genetics Ehf. | Susceptibility gene for myocardial infarction, stroke, and PAOD; methods of treatment |
US7507531B2 (en) | 2002-10-17 | 2009-03-24 | Decode Genetics Chf. | Use of 5-lipoxygenase activating protein (FLAP) gene to assess susceptibility for myocardial infarction |
EP3083564B1 (de) | 2013-12-20 | 2018-07-11 | Novartis AG | Heteroarylbuttersäurederivate als lta4h-hemmer |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5331573A (en) * | 1990-12-14 | 1994-07-19 | Balaji Vitukudi N | Method of design of compounds that mimic conformational features of selected peptides |
US20040137518A1 (en) * | 2002-01-31 | 2004-07-15 | Lambert Millard Hurst | CRYSTALLIZED PPARa LIGAND BINDING DOMAIN POLYPEPTIDE AND SCREENING METHODS EMPLOYING SAME |
-
2000
- 2000-02-28 EP EP00913207A patent/EP1157101B1/de not_active Expired - Lifetime
- 2000-02-28 US US09/914,451 patent/US7590494B1/en not_active Expired - Fee Related
- 2000-02-28 WO PCT/SE2000/000384 patent/WO2000050577A1/en active IP Right Grant
- 2000-02-28 DE DE60031096T patent/DE60031096T2/de not_active Expired - Lifetime
- 2000-02-28 AT AT00913207T patent/ATE341615T1/de not_active IP Right Cessation
- 2000-02-28 AU AU34683/00A patent/AU3468300A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ATE341615T1 (de) | 2006-10-15 |
WO2000050577A1 (en) | 2000-08-31 |
DE60031096T2 (de) | 2007-05-10 |
EP1157101B1 (de) | 2006-10-04 |
US7590494B1 (en) | 2009-09-15 |
AU3468300A (en) | 2000-09-14 |
EP1157101A1 (de) | 2001-11-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: CARDOZ AB, STOCKHOLM, SE |
|
8328 | Change in the person/name/address of the agent |
Representative=s name: PATENT- UND RECHTSANWAELTE KRAUS & WEISERT, 80539 |
|
8364 | No opposition during term of opposition |