DE60029229D1 - Artverwandte-unabhängiger nachweis von microcystin- und nodularin-artverwandten - Google Patents
Artverwandte-unabhängiger nachweis von microcystin- und nodularin-artverwandtenInfo
- Publication number
- DE60029229D1 DE60029229D1 DE60029229T DE60029229T DE60029229D1 DE 60029229 D1 DE60029229 D1 DE 60029229D1 DE 60029229 T DE60029229 T DE 60029229T DE 60029229 T DE60029229 T DE 60029229T DE 60029229 D1 DE60029229 D1 DE 60029229D1
- Authority
- DE
- Germany
- Prior art keywords
- formula
- group represented
- compound
- nodularine
- artworthy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- SRUWWOSWHXIIIA-UKPGNTDSSA-N Cyanoginosin Chemical compound N1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](C)[C@H](C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)C(=C)N(C)C(=O)CC[C@H](C(O)=O)N(C)C(=O)[C@@H](C)[C@@H]1\C=C\C(\C)=C\[C@H](C)[C@@H](O)CC1=CC=CC=C1 SRUWWOSWHXIIIA-UKPGNTDSSA-N 0.000 title 1
- 108010067094 microcystin Proteins 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 239000003053 toxin Substances 0.000 abstract 3
- 231100000765 toxin Toxicity 0.000 abstract 3
- 108700012359 toxins Proteins 0.000 abstract 3
- 239000012530 fluid Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 241000195493 Cryptophyta Species 0.000 abstract 1
- 241000192700 Cyanobacteria Species 0.000 abstract 1
- 238000009007 Diagnostic Kit Methods 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 239000000284 extract Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Monitoring And Testing Of Nuclear Reactors (AREA)
- Measurement Of Radiation (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Luminescent Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99116881 | 1999-09-06 | ||
EP99116881 | 1999-09-06 | ||
PCT/EP2000/008711 WO2001018059A2 (en) | 1999-09-06 | 2000-09-06 | Congener independent detection of microcystin and nodularin congeners |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60029229D1 true DE60029229D1 (de) | 2006-08-17 |
DE60029229T2 DE60029229T2 (de) | 2007-06-28 |
Family
ID=8238867
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60029229T Expired - Lifetime DE60029229T2 (de) | 1999-09-06 | 2000-09-06 | Artverwandte-unabhängiger nachweis von microcystin- und nodularin-artverwandten |
DE1210373T Pending DE1210373T1 (de) | 1999-09-06 | 2000-09-06 | Artverwandte-unabhängiger nachweis von microcystin- und nodularin-artverwandten |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE1210373T Pending DE1210373T1 (de) | 1999-09-06 | 2000-09-06 | Artverwandte-unabhängiger nachweis von microcystin- und nodularin-artverwandten |
Country Status (7)
Country | Link |
---|---|
US (1) | US6967240B1 (de) |
EP (1) | EP1210373B1 (de) |
AT (1) | ATE332312T1 (de) |
AU (1) | AU6842900A (de) |
DE (2) | DE60029229T2 (de) |
ES (1) | ES2267558T3 (de) |
WO (1) | WO2001018059A2 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100387985C (zh) * | 2003-12-05 | 2008-05-14 | 浙江大学 | 水中痕量微囊藻毒素的检测方法 |
US7648844B2 (en) * | 2005-05-02 | 2010-01-19 | Bioscale, Inc. | Method and apparatus for detection of analyte using an acoustic device |
US7611908B2 (en) * | 2005-05-02 | 2009-11-03 | Bioscale, Inc. | Method and apparatus for therapeutic drug monitoring using an acoustic device |
US9739777B1 (en) | 2007-09-06 | 2017-08-22 | Abraxis Inc. | Rapid analysis for cyanobacterial toxins |
JP5832287B2 (ja) * | 2008-07-09 | 2015-12-16 | ジ インスティテュート フォー エスノメディスン | 神経障害に関連する神経毒性アミノ酸を検出するためのイムノアッセイ |
US8394596B1 (en) | 2012-04-13 | 2013-03-12 | Abraxis LLC | Antibodies and assays for beta-N-methylamino-L-alanine |
CN103113877B (zh) * | 2013-01-11 | 2014-08-06 | 长春理工大学 | 一种检测水中微囊藻毒素-lr的荧光探针 |
WO2017109290A1 (en) | 2015-12-21 | 2017-06-29 | Turun Yliopisto | Antibodies against immunocomplexes comprising cyanobacterial cyclic peptide hepatotoxins |
CN107167585B (zh) * | 2017-04-07 | 2018-09-18 | 华南农业大学 | 一种新型小分子结构及其在检测蓝绿藻肝毒素方面的应用 |
US11125750B2 (en) | 2018-06-28 | 2021-09-21 | The University Of Toledo | Methods, assays and kits for detecting exposure to cyanotoxins |
CN109781970B (zh) * | 2019-01-07 | 2022-02-08 | 合肥学院 | 一种评估微囊藻毒素在真实水环境下毒性的方法 |
-
2000
- 2000-09-06 AU AU68429/00A patent/AU6842900A/en not_active Abandoned
- 2000-09-06 ES ES00956519T patent/ES2267558T3/es not_active Expired - Lifetime
- 2000-09-06 DE DE60029229T patent/DE60029229T2/de not_active Expired - Lifetime
- 2000-09-06 AT AT00956519T patent/ATE332312T1/de not_active IP Right Cessation
- 2000-09-06 US US10/070,302 patent/US6967240B1/en not_active Expired - Lifetime
- 2000-09-06 DE DE1210373T patent/DE1210373T1/de active Pending
- 2000-09-06 EP EP00956519A patent/EP1210373B1/de not_active Expired - Lifetime
- 2000-09-06 WO PCT/EP2000/008711 patent/WO2001018059A2/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
WO2001018059A3 (en) | 2001-08-02 |
DE1210373T1 (de) | 2003-06-26 |
ES2267558T3 (es) | 2007-03-16 |
EP1210373A2 (de) | 2002-06-05 |
EP1210373B1 (de) | 2006-07-05 |
AU6842900A (en) | 2001-04-10 |
ATE332312T1 (de) | 2006-07-15 |
WO2001018059A2 (en) | 2001-03-15 |
US6967240B1 (en) | 2005-11-22 |
DE60029229T2 (de) | 2007-06-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: DIETRICH, DANIEL R., NEUWILEN, CH Owner name: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, O, US |