DE60023269D1 - Verfahren zum screenen physiologisch aktiver pyrrol-imidazol derivate - Google Patents

Verfahren zum screenen physiologisch aktiver pyrrol-imidazol derivate

Info

Publication number
DE60023269D1
DE60023269D1 DE60023269T DE60023269T DE60023269D1 DE 60023269 D1 DE60023269 D1 DE 60023269D1 DE 60023269 T DE60023269 T DE 60023269T DE 60023269 T DE60023269 T DE 60023269T DE 60023269 D1 DE60023269 D1 DE 60023269D1
Authority
DE
Germany
Prior art keywords
physiologically active
imidazole derivatives
active pyrrolo
screening
pyrrolo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60023269T
Other languages
English (en)
Other versions
DE60023269T2 (de
Inventor
Hiroshi Sugiyama
Isao Saito
Hirokazu Iida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japan Science and Technology Agency
Original Assignee
Japan Science and Technology Agency
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Science and Technology Agency filed Critical Japan Science and Technology Agency
Application granted granted Critical
Publication of DE60023269D1 publication Critical patent/DE60023269D1/de
Publication of DE60023269T2 publication Critical patent/DE60023269T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DE60023269T 1999-11-16 2000-11-13 Entwicklung eines Screeningverfahrens für ein physiologisch aktives Pyrrol-Imidazol-Derivat Expired - Lifetime DE60023269T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP32600799 1999-11-16
JP32600799A JP2001136974A (ja) 1999-11-16 1999-11-16 生理活性ピロールイミダゾール誘導体のスクリーニング方法
PCT/JP2000/007992 WO2001036677A1 (fr) 1999-11-16 2000-11-13 Mise au point d'un procede de criblage de derives physiologiquement actifs du pyrrole imidazole

Publications (2)

Publication Number Publication Date
DE60023269D1 true DE60023269D1 (de) 2006-03-02
DE60023269T2 DE60023269T2 (de) 2006-07-20

Family

ID=18183062

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60023269T Expired - Lifetime DE60023269T2 (de) 1999-11-16 2000-11-13 Entwicklung eines Screeningverfahrens für ein physiologisch aktives Pyrrol-Imidazol-Derivat

Country Status (5)

Country Link
US (2) US6974668B1 (de)
EP (1) EP1152061B1 (de)
JP (1) JP2001136974A (de)
DE (1) DE60023269T2 (de)
WO (1) WO2001036677A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4061819B2 (ja) 2000-05-12 2008-03-19 独立行政法人科学技術振興機構 インターストランドクロスリンク剤の合成方法
CA2450773C (en) 2001-06-25 2010-08-31 Japan Science And Technology Agency Method of the solid phase synthesis of pyrrole-imidazole polyamide
JP3898532B2 (ja) 2002-03-08 2007-03-28 独立行政法人科学技術振興機構 新規なヘアピン型ポリアミド
US7807844B2 (en) 2003-09-04 2010-10-05 Nihon University TGF-β gene expression inhibitor
JP2007176795A (ja) 2004-08-18 2007-07-12 Univ Nihon ＴＧＦ−β遺伝子発現抑制剤
JP5685081B2 (ja) 2008-04-17 2015-03-18 浩喜 永瀬 マトリックスメタロプロテネース９遺伝子選択的発現抑制剤
CN106068266A (zh) 2013-10-11 2016-11-02 千叶县 以癌症驱动基因的基因突变为靶点进行烷基化的新型烷基化剂
JP2018052930A (ja) 2016-09-21 2018-04-05 千葉県 新規アルキル化剤
EP4365590A2 (de) 2019-03-20 2024-05-08 Juntendo Educational Foundation Mittel zum targeting von organellen-dna mit doppelter membran

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5237991A (en) * 1991-11-19 1993-08-24 Cyberonics, Inc. Implantable medical device with dummy load for pre-implant testing in sterile package and facilitating electrical lead connection
US5273991A (en) * 1992-07-29 1993-12-28 Research Corporation Technologies, Inc. Imidazole-containing compositions and methods of use thereof analogs of distamycin
US5843937A (en) * 1996-05-23 1998-12-01 Panorama Research, Inc. DNA-binding indole derivatives, their prodrugs and immunoconjugates as anticancer agents
EP0986539A1 (de) * 1997-04-06 2000-03-22 California Institute Of Technology Dna-bindende pyrrol- und imidazolpolyamidderivate
JP3649617B2 (ja) * 1999-03-26 2005-05-18 独立行政法人科学技術振興機構 ２本鎖ｄｎａを切断できる化合物及びその使用方法
US8215238B2 (en) 2007-10-10 2012-07-10 The Texas A&M University System Guideway coupling system

Also Published As

Publication number Publication date
JP2001136974A (ja) 2001-05-22
WO2001036677A1 (fr) 2001-05-25
EP1152061A4 (de) 2003-05-28
DE60023269T2 (de) 2006-07-20
EP1152061B1 (de) 2005-10-19
US6974668B1 (en) 2005-12-13
EP1152061A1 (de) 2001-11-07
US7378237B2 (en) 2008-05-27
US20030099998A1 (en) 2003-05-29

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