DE60019619D1 - Dihydrobenzofuranderivate, verfahren zu ihrer herstellung und mittel - Google Patents

Dihydrobenzofuranderivate, verfahren zu ihrer herstellung und mittel

Info

Publication number
DE60019619D1
DE60019619D1 DE60019619T DE60019619T DE60019619D1 DE 60019619 D1 DE60019619 D1 DE 60019619D1 DE 60019619 T DE60019619 T DE 60019619T DE 60019619 T DE60019619 T DE 60019619T DE 60019619 D1 DE60019619 D1 DE 60019619D1
Authority
DE
Germany
Prior art keywords
ring
denotes
substituted
group
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60019619T
Other languages
English (en)
Other versions
DE60019619T2 (de
Inventor
Shigenori Ohkawa
Tadatoshi Hashimoto
Tetsuya Tsukamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DE60019619D1 publication Critical patent/DE60019619D1/de
Publication of DE60019619T2 publication Critical patent/DE60019619T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Furan Compounds (AREA)
DE60019619T 1999-08-20 2000-08-18 Dihydrobenzofuranderivate, verfahren zu ihrer herstellung und mittel Expired - Lifetime DE60019619T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP23471999 1999-08-20
JP23471999 1999-08-20
PCT/JP2000/005524 WO2001014385A1 (fr) 1999-08-20 2000-08-18 Derives de dihydrobenzofuran, leur procede de preparation et agents

Publications (2)

Publication Number Publication Date
DE60019619D1 true DE60019619D1 (de) 2005-05-25
DE60019619T2 DE60019619T2 (de) 2006-03-02

Family

ID=16975313

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60019619T Expired - Lifetime DE60019619T2 (de) 1999-08-20 2000-08-18 Dihydrobenzofuranderivate, verfahren zu ihrer herstellung und mittel

Country Status (7)

Country Link
US (1) US7008940B1 (de)
EP (1) EP1213290B1 (de)
AT (1) ATE293628T1 (de)
AU (1) AU6595000A (de)
CA (1) CA2382418A1 (de)
DE (1) DE60019619T2 (de)
WO (1) WO2001014385A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004092153A1 (ja) 2003-04-14 2004-10-28 Nippon Soda Co. Ltd. ジアミン誘導体、製造法及び抗酸化薬
CA2531020C (en) * 2003-06-26 2014-03-25 Takeda Pharmaceutical Company Limited Cannabinoid receptor modulator
WO2005095434A1 (ja) * 2004-03-31 2005-10-13 Kuraray Co., Ltd. ５α－プレグナン誘導体の製造方法
EP1767540A4 (de) * 2004-03-31 2009-04-01 Kuraray Co Verfahren zur herstellung eines 5-alpha-prägnanderivats
EP2246326A1 (de) * 2009-05-02 2010-11-03 Bayer CropScience AG Verfahren zur Herstellung von Oxindolen und ortho-substituierten Anilinen und ihre Verwendung als Zwischenprodukte für Synthesen

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54163598A (en) 1978-06-13 1979-12-26 Daiichi Seiyaku Co Pyridoquinoline derivative
US5071875A (en) 1989-09-25 1991-12-10 Northwestern University Substituted 2-amidotetralins as melatonin agonists and antagonists
FR2680366B1 (fr) 1991-08-13 1995-01-20 Adir Nouveaux derives d'arylethylamines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
FR2681862B1 (fr) 1991-09-27 1993-11-12 Adir Cie Nouvelles (benzocycloalkyl)alkylamines, leur procede de preparation, et les compositions pharmaceutiques qui les contiennent.
EP0638571A4 (de) * 1992-05-01 1995-04-12 Kowa Co Chinolinderivate oder deren salze und diese enthaltende heilmittel für herzerkrankungen.
FR2713636B1 (fr) 1993-12-07 1996-01-05 Adir Nouveaux dérivés naphtaléniques, leur procédé de préparation, et les compositions pharmaceutiques qui les contiennent.
GB9326192D0 (en) 1993-12-22 1994-02-23 Glaxo Group Ltd Chemical compounds
GB9407919D0 (en) 1994-04-21 1994-06-15 Glaxo Group Ltd Chemical compounds
US5856124A (en) 1994-06-17 1999-01-05 The General Hospital Corporation DNA encoding high-affinity melatonin receptors
US6071946A (en) 1994-10-21 2000-06-06 Adir Et Compagnie Tricyclic urea compounds
FR2725985B1 (fr) 1994-10-21 1996-11-15 Adir Nouveaux composes tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US5998461A (en) 1994-10-21 1999-12-07 Adir Et Compagnie Tricyclic amide compounds
US5661186A (en) 1995-02-24 1997-08-26 Bristol-Myers Squibb Co. Tetralinyl-and indanyl-ethylamides
US6034239A (en) * 1996-03-08 2000-03-07 Takeda Chemical Industries, Ltd. Tricyclic compounds, their production and use
CN100443480C (zh) 1996-03-08 2008-12-17 武田药品工业株式会社 三环化合物及其制备和用途
TW416953B (en) 1996-09-25 2001-01-01 Takeda Chemical Industries Ltd Tricyclic compounds for eliciting a prostaglandin I2 receptor agonistic effect, their production and use
US6872718B1 (en) 1999-08-20 2005-03-29 Takeda Chemical Industries, Ltd. Tricyclic dihydrobenzofuran derivatives, process for the preparation thereof and agents

Also Published As

Publication number Publication date
EP1213290B1 (de) 2005-04-20
CA2382418A1 (en) 2001-03-01
ATE293628T1 (de) 2005-05-15
DE60019619T2 (de) 2006-03-02
WO2001014385A1 (fr) 2001-03-01
AU6595000A (en) 2001-03-19
EP1213290A1 (de) 2002-06-12
US7008940B1 (en) 2006-03-07
EP1213290A4 (de) 2002-09-04

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