DE60014966D1 - Behandlung zur vermeidung von kalzifizierung für fixierte biomaterialien - Google Patents
Behandlung zur vermeidung von kalzifizierung für fixierte biomaterialienInfo
- Publication number
- DE60014966D1 DE60014966D1 DE2000614966 DE60014966T DE60014966D1 DE 60014966 D1 DE60014966 D1 DE 60014966D1 DE 2000614966 DE2000614966 DE 2000614966 DE 60014966 T DE60014966 T DE 60014966T DE 60014966 D1 DE60014966 D1 DE 60014966D1
- Authority
- DE
- Germany
- Prior art keywords
- biomaterials
- treatment
- fixed
- calcification
- avoid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/02—Treatment of implants to prevent calcification or mineralisation in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/459,429 US6479079B1 (en) | 1999-12-13 | 1999-12-13 | Anticalcification treatments for fixed biomaterials |
US459429 | 1999-12-13 | ||
PCT/US2000/033712 WO2001041828A1 (en) | 1999-12-13 | 2000-12-13 | Anticalcification treatments for fixed biomaterials |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60014966D1 true DE60014966D1 (de) | 2004-11-18 |
DE60014966T2 DE60014966T2 (de) | 2006-03-09 |
Family
ID=23824732
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60014966T Expired - Lifetime DE60014966T2 (de) | 1999-12-13 | 2000-12-13 | Behandlung zur vermeidung von kalzifizierung für fixierte biomaterialien |
Country Status (7)
Country | Link |
---|---|
US (1) | US6479079B1 (de) |
EP (1) | EP1239896B1 (de) |
JP (1) | JP2003516191A (de) |
CA (1) | CA2393438C (de) |
DE (1) | DE60014966T2 (de) |
ES (1) | ES2228647T3 (de) |
WO (1) | WO2001041828A1 (de) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6214054B1 (en) | 1998-09-21 | 2001-04-10 | Edwards Lifesciences Corporation | Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby |
US6878168B2 (en) | 2002-01-03 | 2005-04-12 | Edwards Lifesciences Corporation | Treatment of bioprosthetic tissues to mitigate post implantation calcification |
US7189259B2 (en) * | 2002-11-26 | 2007-03-13 | Clemson University | Tissue material and process for bioprosthesis |
CN101010047B (zh) | 2004-02-27 | 2010-12-15 | 奥尔特克斯公司 | 人工心脏瓣膜传送系统 |
EP1796693A2 (de) * | 2004-08-26 | 2007-06-20 | Chandrashekhar P. Pathak | Implantierbare gewebezusammensetzungen und verfahren |
US20060110370A1 (en) * | 2004-11-23 | 2006-05-25 | Pathak Chandrashenkhar P | Treatments for reduction of cytotoxicity and viral contamination of implantable medical devices |
US7989157B2 (en) * | 2005-01-11 | 2011-08-02 | Medtronic, Inc. | Solution for storing bioprosthetic tissue used in a biological prosthesis |
DE102005003632A1 (de) | 2005-01-20 | 2006-08-17 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Katheter für die transvaskuläre Implantation von Herzklappenprothesen |
US8403981B2 (en) | 2006-02-27 | 2013-03-26 | CardiacMC, Inc. | Methods and devices for delivery of prosthetic heart valves and other prosthetics |
US8147541B2 (en) | 2006-02-27 | 2012-04-03 | Aortx, Inc. | Methods and devices for delivery of prosthetic heart valves and other prosthetics |
US8585594B2 (en) | 2006-05-24 | 2013-11-19 | Phoenix Biomedical, Inc. | Methods of assessing inner surfaces of body lumens or organs |
US8500799B2 (en) | 2006-06-20 | 2013-08-06 | Cardiacmd, Inc. | Prosthetic heart valves, support structures and systems and methods for implanting same |
AU2007261046A1 (en) | 2006-06-20 | 2007-12-27 | Aortx, Inc. | Torque shaft and torque drive |
EP2059191A4 (de) | 2006-06-21 | 2010-03-31 | Aortx Inc | Implantiersysteme für eine klappenprothese |
CA2666485C (en) * | 2006-10-27 | 2015-10-06 | Edwards Lifesciences Corporation | Biological tissue for surgical implantation |
US8142805B1 (en) | 2006-11-06 | 2012-03-27 | Clemson University Research Foundation | Implantable devices including fixed tissues |
US7896915B2 (en) | 2007-04-13 | 2011-03-01 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
US9101691B2 (en) | 2007-06-11 | 2015-08-11 | Edwards Lifesciences Corporation | Methods for pre-stressing and capping bioprosthetic tissue |
US9125807B2 (en) | 2007-07-09 | 2015-09-08 | Incept Llc | Adhesive hydrogels for ophthalmic drug delivery |
US8357387B2 (en) | 2007-12-21 | 2013-01-22 | Edwards Lifesciences Corporation | Capping bioprosthetic tissue to reduce calcification |
WO2011104269A1 (en) | 2008-02-26 | 2011-09-01 | Jenavalve Technology Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US9044318B2 (en) | 2008-02-26 | 2015-06-02 | Jenavalve Technology Gmbh | Stent for the positioning and anchoring of a valvular prosthesis |
CN102395401B (zh) | 2009-02-12 | 2015-08-19 | 因赛普特有限责任公司 | 经由水凝胶塞的药物递送 |
AU2010340067B2 (en) | 2009-12-15 | 2015-03-19 | Incept, Llc | Implants and biodegradable fiducial markers |
BR112012023769B1 (pt) | 2010-03-23 | 2020-11-10 | Edwards Lifesciences Corporation | método para preparar material de membrana de tecido bioprotético |
WO2011147849A1 (en) | 2010-05-25 | 2011-12-01 | Jenavalve Technology Inc. | Prosthetic heart valve and transcatheter delivered endoprosthesis comprising a prosthetic heart valve and a stent |
IT1400544B1 (it) | 2010-06-09 | 2013-06-11 | Sorin Biomedica Cardio Srl | Procedimento di detossificazione di tessuto biologico. |
IT1400545B1 (it) | 2010-06-09 | 2013-06-11 | Sorin Biomedica Cardio Srl | Procedimento per la preparazione di tessuto biologico per protesi biologiche. |
US8906601B2 (en) | 2010-06-17 | 2014-12-09 | Edwardss Lifesciences Corporation | Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates |
US8961501B2 (en) | 2010-09-17 | 2015-02-24 | Incept, Llc | Method for applying flowable hydrogels to a cornea |
US9351829B2 (en) | 2010-11-17 | 2016-05-31 | Edwards Lifesciences Corporation | Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability |
US10226417B2 (en) | 2011-09-16 | 2019-03-12 | Peter Jarrett | Drug delivery systems and applications |
JP6001880B2 (ja) * | 2012-03-05 | 2016-10-05 | 株式会社▲吉▼田生物研究所 | 動植物又は出土文化遺物の保存方法 |
US10238771B2 (en) | 2012-11-08 | 2019-03-26 | Edwards Lifesciences Corporation | Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system |
JP6563394B2 (ja) | 2013-08-30 | 2019-08-21 | イェーナヴァルヴ テクノロジー インコーポレイテッド | 人工弁のための径方向に折り畳み自在のフレーム及び当該フレームを製造するための方法 |
US9615922B2 (en) | 2013-09-30 | 2017-04-11 | Edwards Lifesciences Corporation | Method and apparatus for preparing a contoured biological tissue |
US10959839B2 (en) | 2013-10-08 | 2021-03-30 | Edwards Lifesciences Corporation | Method for directing cellular migration patterns on a biological tissue |
US20150122687A1 (en) | 2013-11-06 | 2015-05-07 | Edwards Lifesciences Corporation | Bioprosthetic heart valves having adaptive seals to minimize paravalvular leakage |
US9555162B2 (en) * | 2014-02-24 | 2017-01-31 | Medtronic, Inc. | Phospholipid reduction in biological tissue |
WO2016177562A1 (en) | 2015-05-01 | 2016-11-10 | Jenavalve Technology, Inc. | Device and method with reduced pacemaker rate in heart valve replacement |
EP4183371A1 (de) | 2016-05-13 | 2023-05-24 | JenaValve Technology, Inc. | Herzklappenprotheseneinführungssystem und verfahren zur einführung einer herzklappenprothese mit einführschleuse und ladesystem |
WO2018138658A1 (en) | 2017-01-27 | 2018-08-02 | Jenavalve Technology, Inc. | Heart valve mimicry |
WO2018167536A1 (en) * | 2017-03-15 | 2018-09-20 | Sorin Group Italia S.R.L. | Implantable material and method for preserving |
US11504231B2 (en) | 2018-05-23 | 2022-11-22 | Corcym S.R.L. | Cardiac valve prosthesis |
CN109260517B (zh) * | 2018-09-19 | 2020-10-30 | 杭州启明医疗器械股份有限公司 | 一种可预装干燥生物心脏瓣膜及其制备方法 |
CA3116158A1 (en) | 2018-11-01 | 2020-05-07 | Edwards Lifesciences Corporation | Transcatheter pulmonic regenerative valve |
EP3693030A1 (de) | 2019-02-07 | 2020-08-12 | P+F Products + Features GmbH | Verfahren zur herstellung von biologischem gewebe für die chirurgische implantation |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4259472A (en) | 1980-01-04 | 1981-03-31 | Ford Motor Company | Two component oligomeric phosphate/isocyanate composition |
US4323358A (en) | 1981-04-30 | 1982-04-06 | Vascor, Inc. | Method for inhibiting mineralization of natural tissue during implantation |
US5215541A (en) | 1982-11-12 | 1993-06-01 | Baxter International Inc. | Surfactant treatment of implantable biological tissue to inhibit calcification |
US4755593A (en) * | 1985-07-24 | 1988-07-05 | Lauren Mark D | Novel biomaterial of cross-linked peritoneal tissue |
US5263992A (en) | 1986-10-17 | 1993-11-23 | Bio-Metric Systems, Inc. | Biocompatible device with covalently bonded biocompatible agent |
US4838888A (en) | 1987-04-17 | 1989-06-13 | Baxter Travenol Laboratories, Inc. | Calcification mitigation of implantable bioprostheses |
US5147514A (en) | 1987-08-02 | 1992-09-15 | University Of North Carolina | Process for cross-linking collagenous material and resulting product |
US5098960A (en) | 1987-09-23 | 1992-03-24 | Board Of Reagents, The University Of Texas System | Methods and compositions for providing articles having improved biocompatibility characteristics |
US4976733A (en) * | 1988-02-03 | 1990-12-11 | Biomedical Design, Inc. | Prevention of prosthesis calcification |
US5746775A (en) | 1988-04-01 | 1998-05-05 | The Board Of Regent6S Of The University Of Michigan | Method of making calcification-resistant bioprosthetic tissue |
CA2022480C (en) | 1989-08-02 | 2001-02-27 | Gerald L. Mechanic | Process for cross-linking collagenous materials and resulting product |
EP0526550B1 (de) | 1990-04-24 | 1997-12-29 | EISENBERG, Mark | Zusammengesetztes äquivalent der lebenden haut |
US5476516A (en) * | 1992-03-13 | 1995-12-19 | Albert Einstein College Of Medicine Of Yeshiva University | Anticalcification treatment for aldehyde-tanned biological tissue |
FR2692582B1 (fr) | 1992-06-18 | 1998-09-18 | Flamel Tech Sa | Nouveaux derives reticulables de collagene, leur procede d'obtention et leur application a la preparation de biomateriaux. |
US5436291A (en) | 1992-07-09 | 1995-07-25 | University Of Michigan, The Board Of . . . | Calcification-resistant synthetic biomaterials |
US5296583A (en) | 1992-07-09 | 1994-03-22 | University Of Michigan | Calcification-resistant synthetic biomaterials |
US5447536A (en) | 1994-02-17 | 1995-09-05 | Biomedical Design, Inc. | Method for fixation of biological tissue |
KR0131046B1 (ko) | 1994-07-13 | 1998-04-14 | 김은영 | 항석회화 생체 조직 인공 심장 판막 |
US5931969A (en) | 1994-07-29 | 1999-08-03 | Baxter International Inc. | Methods and apparatuses for treating biological tissue to mitigate calcification |
AU692330B2 (en) | 1994-12-30 | 1998-06-04 | National University Of Singapore, The | Method for reducing calcification of biological tissue used in implantable bioprostheses |
US5645587A (en) | 1996-06-05 | 1997-07-08 | Chanda; Jyotirmay | Prevention of calcification and degeneration of biological tissue grafts for implantation in humans |
US5958669A (en) | 1997-05-02 | 1999-09-28 | St. Jude Medical, Inc. | Apparatus and method for crosslinking to fix tissue or crosslink molecules to tissue |
US6027530A (en) | 1997-12-24 | 2000-02-22 | Baxter International Inc. | System, apparatus and method for chemical fixation of stentless cardiac valvular bioprostheses |
US6156531A (en) * | 1998-07-20 | 2000-12-05 | Sulzer Carbomedics Inc. | Cross-linking tissue with a compound having a C8 to C40 aliphatic chain |
-
1999
- 1999-12-13 US US09/459,429 patent/US6479079B1/en not_active Expired - Lifetime
-
2000
- 2000-12-13 DE DE60014966T patent/DE60014966T2/de not_active Expired - Lifetime
- 2000-12-13 CA CA002393438A patent/CA2393438C/en not_active Expired - Fee Related
- 2000-12-13 WO PCT/US2000/033712 patent/WO2001041828A1/en active IP Right Grant
- 2000-12-13 EP EP00986340A patent/EP1239896B1/de not_active Expired - Lifetime
- 2000-12-13 ES ES00986340T patent/ES2228647T3/es not_active Expired - Lifetime
- 2000-12-13 JP JP2001543172A patent/JP2003516191A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP1239896A1 (de) | 2002-09-18 |
CA2393438C (en) | 2008-12-09 |
WO2001041828A1 (en) | 2001-06-14 |
US6479079B1 (en) | 2002-11-12 |
ES2228647T3 (es) | 2005-04-16 |
DE60014966T2 (de) | 2006-03-09 |
WO2001041828B1 (en) | 2001-11-15 |
EP1239896B1 (de) | 2004-10-13 |
CA2393438A1 (en) | 2001-06-14 |
JP2003516191A (ja) | 2003-05-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |