DE60014966D1 - Behandlung zur vermeidung von kalzifizierung für fixierte biomaterialien - Google Patents

Behandlung zur vermeidung von kalzifizierung für fixierte biomaterialien

Info

Publication number
DE60014966D1
DE60014966D1 DE2000614966 DE60014966T DE60014966D1 DE 60014966 D1 DE60014966 D1 DE 60014966D1 DE 2000614966 DE2000614966 DE 2000614966 DE 60014966 T DE60014966 T DE 60014966T DE 60014966 D1 DE60014966 D1 DE 60014966D1
Authority
DE
Germany
Prior art keywords
biomaterials
treatment
fixed
calcification
avoid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE2000614966
Other languages
English (en)
Other versions
DE60014966T2 (de
Inventor
P Pathak
A Moore
E Phillips
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Carbomedics Inc
Original Assignee
Carbomedics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carbomedics Inc filed Critical Carbomedics Inc
Publication of DE60014966D1 publication Critical patent/DE60014966D1/de
Application granted granted Critical
Publication of DE60014966T2 publication Critical patent/DE60014966T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/02Treatment of implants to prevent calcification or mineralisation in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
DE60014966T 1999-12-13 2000-12-13 Behandlung zur vermeidung von kalzifizierung für fixierte biomaterialien Expired - Lifetime DE60014966T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US459429 1999-12-13
US09/459,429 US6479079B1 (en) 1999-12-13 1999-12-13 Anticalcification treatments for fixed biomaterials
PCT/US2000/033712 WO2001041828A1 (en) 1999-12-13 2000-12-13 Anticalcification treatments for fixed biomaterials

Publications (2)

Publication Number Publication Date
DE60014966D1 true DE60014966D1 (de) 2004-11-18
DE60014966T2 DE60014966T2 (de) 2006-03-09

Family

ID=23824732

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60014966T Expired - Lifetime DE60014966T2 (de) 1999-12-13 2000-12-13 Behandlung zur vermeidung von kalzifizierung für fixierte biomaterialien

Country Status (7)

Country Link
US (1) US6479079B1 (de)
EP (1) EP1239896B1 (de)
JP (1) JP2003516191A (de)
CA (1) CA2393438C (de)
DE (1) DE60014966T2 (de)
ES (1) ES2228647T3 (de)
WO (1) WO2001041828A1 (de)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6214054B1 (en) 1998-09-21 2001-04-10 Edwards Lifesciences Corporation Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby
US6878168B2 (en) 2002-01-03 2005-04-12 Edwards Lifesciences Corporation Treatment of bioprosthetic tissues to mitigate post implantation calcification
US7189259B2 (en) * 2002-11-26 2007-03-13 Clemson University Tissue material and process for bioprosthesis
CN102488572A (zh) 2004-02-27 2012-06-13 奥尔特克斯公司 人工心脏瓣膜传送系统和方法
EP1796693A2 (de) * 2004-08-26 2007-06-20 Chandrashekhar P. Pathak Implantierbare gewebezusammensetzungen und verfahren
US20060110370A1 (en) * 2004-11-23 2006-05-25 Pathak Chandrashenkhar P Treatments for reduction of cytotoxicity and viral contamination of implantable medical devices
US7989157B2 (en) * 2005-01-11 2011-08-02 Medtronic, Inc. Solution for storing bioprosthetic tissue used in a biological prosthesis
DE102005003632A1 (de) 2005-01-20 2006-08-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Katheter für die transvaskuläre Implantation von Herzklappenprothesen
US8403981B2 (en) 2006-02-27 2013-03-26 CardiacMC, Inc. Methods and devices for delivery of prosthetic heart valves and other prosthetics
US8147541B2 (en) 2006-02-27 2012-04-03 Aortx, Inc. Methods and devices for delivery of prosthetic heart valves and other prosthetics
US8585594B2 (en) 2006-05-24 2013-11-19 Phoenix Biomedical, Inc. Methods of assessing inner surfaces of body lumens or organs
JP2009540955A (ja) 2006-06-20 2009-11-26 エーオーテックス, インコーポレイテッド 人工心臓弁、支持構造ならびにこれらを移植するシステムおよび方法
EP2035723A4 (de) 2006-06-20 2011-11-30 Aortx Inc Drehmomentwelle und drehmomentantrieb
AU2007260951A1 (en) 2006-06-21 2007-12-27 Aortx, Inc. Prosthetic valve implantation systems
WO2008073582A2 (en) 2006-10-27 2008-06-19 Edwards Lifesciences Corporation Biological tissue for surgical implantation
US8142805B1 (en) 2006-11-06 2012-03-27 Clemson University Research Foundation Implantable devices including fixed tissues
US7896915B2 (en) 2007-04-13 2011-03-01 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
US9101691B2 (en) 2007-06-11 2015-08-11 Edwards Lifesciences Corporation Methods for pre-stressing and capping bioprosthetic tissue
US9125807B2 (en) 2007-07-09 2015-09-08 Incept Llc Adhesive hydrogels for ophthalmic drug delivery
US8357387B2 (en) 2007-12-21 2013-01-22 Edwards Lifesciences Corporation Capping bioprosthetic tissue to reduce calcification
ES2903231T3 (es) 2008-02-26 2022-03-31 Jenavalve Tech Inc Stent para el posicionamiento y anclaje de una prótesis valvular en un sitio de implantación en el corazón de un paciente
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
AU2010213612B2 (en) 2009-02-12 2015-04-30 Incept, Llc Drug delivery through hydrogel plugs
CA3042067C (en) 2009-12-15 2022-10-18 Incept, Llc Implants and biodegradable fiducial markers
NZ602706A (en) 2010-03-23 2014-02-28 Edwards Lifesciences Corp Methods of conditioning sheet bioprosthetic tissue
BR112012029896A2 (pt) 2010-05-25 2017-06-20 Jenavalve Tech Inc válcula cardíaca protética para endoprótese e endoprótese
IT1400544B1 (it) 2010-06-09 2013-06-11 Sorin Biomedica Cardio Srl Procedimento di detossificazione di tessuto biologico.
IT1400545B1 (it) 2010-06-09 2013-06-11 Sorin Biomedica Cardio Srl Procedimento per la preparazione di tessuto biologico per protesi biologiche.
CA2794135C (en) 2010-06-17 2018-01-02 Edwards Lifesciences Corporation Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates
US8906601B2 (en) 2010-06-17 2014-12-09 Edwardss Lifesciences Corporation Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates
US8961501B2 (en) 2010-09-17 2015-02-24 Incept, Llc Method for applying flowable hydrogels to a cornea
US9351829B2 (en) 2010-11-17 2016-05-31 Edwards Lifesciences Corporation Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability
US10226417B2 (en) 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications
JP6001880B2 (ja) * 2012-03-05 2016-10-05 株式会社▲吉▼田生物研究所 動植物又は出土文化遺物の保存方法
US10238771B2 (en) 2012-11-08 2019-03-26 Edwards Lifesciences Corporation Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system
EP4098226A1 (de) 2013-08-30 2022-12-07 JenaValve Technology, Inc. Endoprothese mit einem radial zusammenklappbaren rahmen und einer klappenprothese
US9615922B2 (en) 2013-09-30 2017-04-11 Edwards Lifesciences Corporation Method and apparatus for preparing a contoured biological tissue
US10959839B2 (en) 2013-10-08 2021-03-30 Edwards Lifesciences Corporation Method for directing cellular migration patterns on a biological tissue
US20150122687A1 (en) 2013-11-06 2015-05-07 Edwards Lifesciences Corporation Bioprosthetic heart valves having adaptive seals to minimize paravalvular leakage
US9555162B2 (en) * 2014-02-24 2017-01-31 Medtronic, Inc. Phospholipid reduction in biological tissue
CN107405198B (zh) 2015-03-20 2021-04-20 耶拿阀门科技股份有限公司 心脏瓣膜假体输送系统和用导入器鞘输送心脏瓣膜假体的方法
EP4403138A3 (de) 2015-05-01 2024-10-09 JenaValve Technology, Inc. Vorrichtung und verfahren mit reduzierter herzschrittmacherrate bei herzklappenersatz
JP7081749B2 (ja) 2016-05-13 2022-06-07 イエナバルブ テクノロジー インク 心臓弁プロテーゼ送達システム
WO2018138658A1 (en) 2017-01-27 2018-08-02 Jenavalve Technology, Inc. Heart valve mimicry
WO2018167536A1 (en) * 2017-03-15 2018-09-20 Sorin Group Italia S.R.L. Implantable material and method for preserving
WO2018222434A1 (en) 2017-05-31 2018-12-06 Edwards Lifesciences Corporation Collagen fibers and articles formed therefrom
CA3081049A1 (en) 2018-01-23 2019-08-01 Edwards Lifesciences Corporation Method for pre-stretching implantable biocompatible materials, and materials and devices produced thereby
EP3796873B1 (de) 2018-05-23 2022-04-27 Corcym S.r.l. Herzklappenprothese
CN109260517B (zh) * 2018-09-19 2020-10-30 杭州启明医疗器械股份有限公司 一种可预装干燥生物心脏瓣膜及其制备方法
US11517428B2 (en) 2018-11-01 2022-12-06 Edwards Lifesciences Corporation Transcatheter pulmonic regenerative valve
EP3693030A1 (de) 2019-02-07 2020-08-12 P+F Products + Features GmbH Verfahren zur herstellung von biologischem gewebe für die chirurgische implantation

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4259472A (en) 1980-01-04 1981-03-31 Ford Motor Company Two component oligomeric phosphate/isocyanate composition
US4323358A (en) 1981-04-30 1982-04-06 Vascor, Inc. Method for inhibiting mineralization of natural tissue during implantation
US5215541A (en) 1982-11-12 1993-06-01 Baxter International Inc. Surfactant treatment of implantable biological tissue to inhibit calcification
US4755593A (en) * 1985-07-24 1988-07-05 Lauren Mark D Novel biomaterial of cross-linked peritoneal tissue
US5263992A (en) 1986-10-17 1993-11-23 Bio-Metric Systems, Inc. Biocompatible device with covalently bonded biocompatible agent
US4838888A (en) 1987-04-17 1989-06-13 Baxter Travenol Laboratories, Inc. Calcification mitigation of implantable bioprostheses
US5147514A (en) 1987-08-02 1992-09-15 University Of North Carolina Process for cross-linking collagenous material and resulting product
US5098960A (en) 1987-09-23 1992-03-24 Board Of Reagents, The University Of Texas System Methods and compositions for providing articles having improved biocompatibility characteristics
US4976733A (en) * 1988-02-03 1990-12-11 Biomedical Design, Inc. Prevention of prosthesis calcification
US5746775A (en) 1988-04-01 1998-05-05 The Board Of Regent6S Of The University Of Michigan Method of making calcification-resistant bioprosthetic tissue
ES2109230T3 (es) 1989-08-02 1998-01-16 Univ North Carolina Procedimiento para reticular materiales colaginosos y producto resultante.
US5282859A (en) 1990-04-24 1994-02-01 Mark Eisenberg Composite living skin equivalents
US5476516A (en) * 1992-03-13 1995-12-19 Albert Einstein College Of Medicine Of Yeshiva University Anticalcification treatment for aldehyde-tanned biological tissue
FR2692582B1 (fr) 1992-06-18 1998-09-18 Flamel Tech Sa Nouveaux derives reticulables de collagene, leur procede d'obtention et leur application a la preparation de biomateriaux.
US5296583A (en) 1992-07-09 1994-03-22 University Of Michigan Calcification-resistant synthetic biomaterials
US5436291A (en) 1992-07-09 1995-07-25 University Of Michigan, The Board Of . . . Calcification-resistant synthetic biomaterials
US5447536A (en) 1994-02-17 1995-09-05 Biomedical Design, Inc. Method for fixation of biological tissue
KR0131046B1 (ko) 1994-07-13 1998-04-14 김은영 항석회화 생체 조직 인공 심장 판막
US5931969A (en) 1994-07-29 1999-08-03 Baxter International Inc. Methods and apparatuses for treating biological tissue to mitigate calcification
AU692330B2 (en) 1994-12-30 1998-06-04 National University Of Singapore, The Method for reducing calcification of biological tissue used in implantable bioprostheses
US5645587A (en) 1996-06-05 1997-07-08 Chanda; Jyotirmay Prevention of calcification and degeneration of biological tissue grafts for implantation in humans
US5958669A (en) 1997-05-02 1999-09-28 St. Jude Medical, Inc. Apparatus and method for crosslinking to fix tissue or crosslink molecules to tissue
US6027530A (en) 1997-12-24 2000-02-22 Baxter International Inc. System, apparatus and method for chemical fixation of stentless cardiac valvular bioprostheses
US6156531A (en) * 1998-07-20 2000-12-05 Sulzer Carbomedics Inc. Cross-linking tissue with a compound having a C8 to C40 aliphatic chain

Also Published As

Publication number Publication date
WO2001041828B1 (en) 2001-11-15
CA2393438C (en) 2008-12-09
ES2228647T3 (es) 2005-04-16
EP1239896B1 (de) 2004-10-13
US6479079B1 (en) 2002-11-12
WO2001041828A1 (en) 2001-06-14
CA2393438A1 (en) 2001-06-14
EP1239896A1 (de) 2002-09-18
DE60014966T2 (de) 2006-03-09
JP2003516191A (ja) 2003-05-13

Similar Documents

Publication Publication Date Title
DE60014966D1 (de) Behandlung zur vermeidung von kalzifizierung für fixierte biomaterialien
ATE247987T1 (de) Behandlung zur beseitigung von gerüchen
DE60025369D1 (de) Unterchlorige säure enthaltendes superoxidiertes wasser zur behandlung von wunden
DE50009504D1 (de) Verwendung von retigabin zur behandlung von neuropathischen schmerzen
DE60019556D1 (de) 2-amino-benzoxazinonderivate zur behandlung von fettleibigkeit
DE60023043T2 (de) (S,S)-Reboxetin zur Behandlung von Inkontinenz
ATE308997T1 (de) Mittel zur behandlung von erkrankungen der speiseröhre
DE60001421D1 (de) Behandlung von abgas
DE60031710D1 (de) Fettsäurederivat zur behandlung von externen sekretionsstörungen
DE60011570D1 (de) Arylpiperazinyl-cyclohexyl indolderivate zur behandlung von depressionen
DE60029033D1 (de) Verfahren zur Behandlung von Tissuepapier
DE60023872D1 (de) Verfahren zur erhöhung der biologischen effektivität von zusammensetzungen zur pflanzenbehandlung
DE10082139T1 (de) Zusammensetzung zur Behandlung von Reibungspaaren
DE60019158D1 (de) Neue oxabispidin-verbindungen zur behandlung von herzarrhythmien
ATE291427T1 (de) Verwendung von optisch reinem (+)-norcisapride für die behandlung des reizdarmsyndroms
ATE293447T1 (de) 2-oxy-benzoxazinonderivate zur behandlung von fettleibigkeit
ATE263777T1 (de) Zusammensetzungen zur behandlung von entzündungsreaktionen
DE60030210D1 (de) Elektrolytisches Behandlungsverfahren
DE60136477D1 (de) Retinoide zur behandlung von emphysem
DE60014928D1 (de) Retinoide zur behandlung von emphysem
ATE254913T1 (de) Diacerein zur behandlung von psoriasis
DE60130661D1 (de) Verwendung der 13-cis retinsäure zur behandlung von emphysemen
DE60035326D1 (de) Verfahren zur Behandlung von Abwasser
ATE493125T1 (de) Carbamatverbindungen zur behandlung von schmerz
DE50105735D1 (de) Chlorzoxazon zur behandlung von psoriasis

Legal Events

Date Code Title Description
8364 No opposition during term of opposition