DE60014966D1 - Behandlung zur vermeidung von kalzifizierung für fixierte biomaterialien - Google Patents
Behandlung zur vermeidung von kalzifizierung für fixierte biomaterialienInfo
- Publication number
- DE60014966D1 DE60014966D1 DE2000614966 DE60014966T DE60014966D1 DE 60014966 D1 DE60014966 D1 DE 60014966D1 DE 2000614966 DE2000614966 DE 2000614966 DE 60014966 T DE60014966 T DE 60014966T DE 60014966 D1 DE60014966 D1 DE 60014966D1
- Authority
- DE
- Germany
- Prior art keywords
- biomaterials
- treatment
- fixed
- calcification
- avoid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/02—Treatment of implants to prevent calcification or mineralisation in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- General Chemical & Material Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US459429 | 1999-12-13 | ||
US09/459,429 US6479079B1 (en) | 1999-12-13 | 1999-12-13 | Anticalcification treatments for fixed biomaterials |
PCT/US2000/033712 WO2001041828A1 (en) | 1999-12-13 | 2000-12-13 | Anticalcification treatments for fixed biomaterials |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60014966D1 true DE60014966D1 (de) | 2004-11-18 |
DE60014966T2 DE60014966T2 (de) | 2006-03-09 |
Family
ID=23824732
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60014966T Expired - Lifetime DE60014966T2 (de) | 1999-12-13 | 2000-12-13 | Behandlung zur vermeidung von kalzifizierung für fixierte biomaterialien |
Country Status (7)
Country | Link |
---|---|
US (1) | US6479079B1 (de) |
EP (1) | EP1239896B1 (de) |
JP (1) | JP2003516191A (de) |
CA (1) | CA2393438C (de) |
DE (1) | DE60014966T2 (de) |
ES (1) | ES2228647T3 (de) |
WO (1) | WO2001041828A1 (de) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6214054B1 (en) | 1998-09-21 | 2001-04-10 | Edwards Lifesciences Corporation | Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby |
US6878168B2 (en) | 2002-01-03 | 2005-04-12 | Edwards Lifesciences Corporation | Treatment of bioprosthetic tissues to mitigate post implantation calcification |
US7189259B2 (en) * | 2002-11-26 | 2007-03-13 | Clemson University | Tissue material and process for bioprosthesis |
CN102488572A (zh) | 2004-02-27 | 2012-06-13 | 奥尔特克斯公司 | 人工心脏瓣膜传送系统和方法 |
EP1796693A2 (de) * | 2004-08-26 | 2007-06-20 | Chandrashekhar P. Pathak | Implantierbare gewebezusammensetzungen und verfahren |
US20060110370A1 (en) * | 2004-11-23 | 2006-05-25 | Pathak Chandrashenkhar P | Treatments for reduction of cytotoxicity and viral contamination of implantable medical devices |
US7989157B2 (en) * | 2005-01-11 | 2011-08-02 | Medtronic, Inc. | Solution for storing bioprosthetic tissue used in a biological prosthesis |
DE102005003632A1 (de) | 2005-01-20 | 2006-08-17 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Katheter für die transvaskuläre Implantation von Herzklappenprothesen |
US8403981B2 (en) | 2006-02-27 | 2013-03-26 | CardiacMC, Inc. | Methods and devices for delivery of prosthetic heart valves and other prosthetics |
US8147541B2 (en) | 2006-02-27 | 2012-04-03 | Aortx, Inc. | Methods and devices for delivery of prosthetic heart valves and other prosthetics |
US8585594B2 (en) | 2006-05-24 | 2013-11-19 | Phoenix Biomedical, Inc. | Methods of assessing inner surfaces of body lumens or organs |
JP2009540955A (ja) | 2006-06-20 | 2009-11-26 | エーオーテックス, インコーポレイテッド | 人工心臓弁、支持構造ならびにこれらを移植するシステムおよび方法 |
EP2035723A4 (de) | 2006-06-20 | 2011-11-30 | Aortx Inc | Drehmomentwelle und drehmomentantrieb |
AU2007260951A1 (en) | 2006-06-21 | 2007-12-27 | Aortx, Inc. | Prosthetic valve implantation systems |
WO2008073582A2 (en) | 2006-10-27 | 2008-06-19 | Edwards Lifesciences Corporation | Biological tissue for surgical implantation |
US8142805B1 (en) | 2006-11-06 | 2012-03-27 | Clemson University Research Foundation | Implantable devices including fixed tissues |
US7896915B2 (en) | 2007-04-13 | 2011-03-01 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
US9101691B2 (en) | 2007-06-11 | 2015-08-11 | Edwards Lifesciences Corporation | Methods for pre-stressing and capping bioprosthetic tissue |
US9125807B2 (en) | 2007-07-09 | 2015-09-08 | Incept Llc | Adhesive hydrogels for ophthalmic drug delivery |
US8357387B2 (en) | 2007-12-21 | 2013-01-22 | Edwards Lifesciences Corporation | Capping bioprosthetic tissue to reduce calcification |
ES2903231T3 (es) | 2008-02-26 | 2022-03-31 | Jenavalve Tech Inc | Stent para el posicionamiento y anclaje de una prótesis valvular en un sitio de implantación en el corazón de un paciente |
US9044318B2 (en) | 2008-02-26 | 2015-06-02 | Jenavalve Technology Gmbh | Stent for the positioning and anchoring of a valvular prosthesis |
AU2010213612B2 (en) | 2009-02-12 | 2015-04-30 | Incept, Llc | Drug delivery through hydrogel plugs |
CA3042067C (en) | 2009-12-15 | 2022-10-18 | Incept, Llc | Implants and biodegradable fiducial markers |
NZ602706A (en) | 2010-03-23 | 2014-02-28 | Edwards Lifesciences Corp | Methods of conditioning sheet bioprosthetic tissue |
BR112012029896A2 (pt) | 2010-05-25 | 2017-06-20 | Jenavalve Tech Inc | válcula cardíaca protética para endoprótese e endoprótese |
IT1400544B1 (it) | 2010-06-09 | 2013-06-11 | Sorin Biomedica Cardio Srl | Procedimento di detossificazione di tessuto biologico. |
IT1400545B1 (it) | 2010-06-09 | 2013-06-11 | Sorin Biomedica Cardio Srl | Procedimento per la preparazione di tessuto biologico per protesi biologiche. |
CA2794135C (en) | 2010-06-17 | 2018-01-02 | Edwards Lifesciences Corporation | Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates |
US8906601B2 (en) | 2010-06-17 | 2014-12-09 | Edwardss Lifesciences Corporation | Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates |
US8961501B2 (en) | 2010-09-17 | 2015-02-24 | Incept, Llc | Method for applying flowable hydrogels to a cornea |
US9351829B2 (en) | 2010-11-17 | 2016-05-31 | Edwards Lifesciences Corporation | Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability |
US10226417B2 (en) | 2011-09-16 | 2019-03-12 | Peter Jarrett | Drug delivery systems and applications |
JP6001880B2 (ja) * | 2012-03-05 | 2016-10-05 | 株式会社▲吉▼田生物研究所 | 動植物又は出土文化遺物の保存方法 |
US10238771B2 (en) | 2012-11-08 | 2019-03-26 | Edwards Lifesciences Corporation | Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system |
EP4098226A1 (de) | 2013-08-30 | 2022-12-07 | JenaValve Technology, Inc. | Endoprothese mit einem radial zusammenklappbaren rahmen und einer klappenprothese |
US9615922B2 (en) | 2013-09-30 | 2017-04-11 | Edwards Lifesciences Corporation | Method and apparatus for preparing a contoured biological tissue |
US10959839B2 (en) | 2013-10-08 | 2021-03-30 | Edwards Lifesciences Corporation | Method for directing cellular migration patterns on a biological tissue |
US20150122687A1 (en) | 2013-11-06 | 2015-05-07 | Edwards Lifesciences Corporation | Bioprosthetic heart valves having adaptive seals to minimize paravalvular leakage |
US9555162B2 (en) * | 2014-02-24 | 2017-01-31 | Medtronic, Inc. | Phospholipid reduction in biological tissue |
CN107405198B (zh) | 2015-03-20 | 2021-04-20 | 耶拿阀门科技股份有限公司 | 心脏瓣膜假体输送系统和用导入器鞘输送心脏瓣膜假体的方法 |
EP4403138A3 (de) | 2015-05-01 | 2024-10-09 | JenaValve Technology, Inc. | Vorrichtung und verfahren mit reduzierter herzschrittmacherrate bei herzklappenersatz |
JP7081749B2 (ja) | 2016-05-13 | 2022-06-07 | イエナバルブ テクノロジー インク | 心臓弁プロテーゼ送達システム |
WO2018138658A1 (en) | 2017-01-27 | 2018-08-02 | Jenavalve Technology, Inc. | Heart valve mimicry |
WO2018167536A1 (en) * | 2017-03-15 | 2018-09-20 | Sorin Group Italia S.R.L. | Implantable material and method for preserving |
WO2018222434A1 (en) | 2017-05-31 | 2018-12-06 | Edwards Lifesciences Corporation | Collagen fibers and articles formed therefrom |
CA3081049A1 (en) | 2018-01-23 | 2019-08-01 | Edwards Lifesciences Corporation | Method for pre-stretching implantable biocompatible materials, and materials and devices produced thereby |
EP3796873B1 (de) | 2018-05-23 | 2022-04-27 | Corcym S.r.l. | Herzklappenprothese |
CN109260517B (zh) * | 2018-09-19 | 2020-10-30 | 杭州启明医疗器械股份有限公司 | 一种可预装干燥生物心脏瓣膜及其制备方法 |
US11517428B2 (en) | 2018-11-01 | 2022-12-06 | Edwards Lifesciences Corporation | Transcatheter pulmonic regenerative valve |
EP3693030A1 (de) | 2019-02-07 | 2020-08-12 | P+F Products + Features GmbH | Verfahren zur herstellung von biologischem gewebe für die chirurgische implantation |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4259472A (en) | 1980-01-04 | 1981-03-31 | Ford Motor Company | Two component oligomeric phosphate/isocyanate composition |
US4323358A (en) | 1981-04-30 | 1982-04-06 | Vascor, Inc. | Method for inhibiting mineralization of natural tissue during implantation |
US5215541A (en) | 1982-11-12 | 1993-06-01 | Baxter International Inc. | Surfactant treatment of implantable biological tissue to inhibit calcification |
US4755593A (en) * | 1985-07-24 | 1988-07-05 | Lauren Mark D | Novel biomaterial of cross-linked peritoneal tissue |
US5263992A (en) | 1986-10-17 | 1993-11-23 | Bio-Metric Systems, Inc. | Biocompatible device with covalently bonded biocompatible agent |
US4838888A (en) | 1987-04-17 | 1989-06-13 | Baxter Travenol Laboratories, Inc. | Calcification mitigation of implantable bioprostheses |
US5147514A (en) | 1987-08-02 | 1992-09-15 | University Of North Carolina | Process for cross-linking collagenous material and resulting product |
US5098960A (en) | 1987-09-23 | 1992-03-24 | Board Of Reagents, The University Of Texas System | Methods and compositions for providing articles having improved biocompatibility characteristics |
US4976733A (en) * | 1988-02-03 | 1990-12-11 | Biomedical Design, Inc. | Prevention of prosthesis calcification |
US5746775A (en) | 1988-04-01 | 1998-05-05 | The Board Of Regent6S Of The University Of Michigan | Method of making calcification-resistant bioprosthetic tissue |
ES2109230T3 (es) | 1989-08-02 | 1998-01-16 | Univ North Carolina | Procedimiento para reticular materiales colaginosos y producto resultante. |
US5282859A (en) | 1990-04-24 | 1994-02-01 | Mark Eisenberg | Composite living skin equivalents |
US5476516A (en) * | 1992-03-13 | 1995-12-19 | Albert Einstein College Of Medicine Of Yeshiva University | Anticalcification treatment for aldehyde-tanned biological tissue |
FR2692582B1 (fr) | 1992-06-18 | 1998-09-18 | Flamel Tech Sa | Nouveaux derives reticulables de collagene, leur procede d'obtention et leur application a la preparation de biomateriaux. |
US5296583A (en) | 1992-07-09 | 1994-03-22 | University Of Michigan | Calcification-resistant synthetic biomaterials |
US5436291A (en) | 1992-07-09 | 1995-07-25 | University Of Michigan, The Board Of . . . | Calcification-resistant synthetic biomaterials |
US5447536A (en) | 1994-02-17 | 1995-09-05 | Biomedical Design, Inc. | Method for fixation of biological tissue |
KR0131046B1 (ko) | 1994-07-13 | 1998-04-14 | 김은영 | 항석회화 생체 조직 인공 심장 판막 |
US5931969A (en) | 1994-07-29 | 1999-08-03 | Baxter International Inc. | Methods and apparatuses for treating biological tissue to mitigate calcification |
AU692330B2 (en) | 1994-12-30 | 1998-06-04 | National University Of Singapore, The | Method for reducing calcification of biological tissue used in implantable bioprostheses |
US5645587A (en) | 1996-06-05 | 1997-07-08 | Chanda; Jyotirmay | Prevention of calcification and degeneration of biological tissue grafts for implantation in humans |
US5958669A (en) | 1997-05-02 | 1999-09-28 | St. Jude Medical, Inc. | Apparatus and method for crosslinking to fix tissue or crosslink molecules to tissue |
US6027530A (en) | 1997-12-24 | 2000-02-22 | Baxter International Inc. | System, apparatus and method for chemical fixation of stentless cardiac valvular bioprostheses |
US6156531A (en) * | 1998-07-20 | 2000-12-05 | Sulzer Carbomedics Inc. | Cross-linking tissue with a compound having a C8 to C40 aliphatic chain |
-
1999
- 1999-12-13 US US09/459,429 patent/US6479079B1/en not_active Expired - Lifetime
-
2000
- 2000-12-13 ES ES00986340T patent/ES2228647T3/es not_active Expired - Lifetime
- 2000-12-13 DE DE60014966T patent/DE60014966T2/de not_active Expired - Lifetime
- 2000-12-13 CA CA002393438A patent/CA2393438C/en not_active Expired - Fee Related
- 2000-12-13 EP EP00986340A patent/EP1239896B1/de not_active Expired - Lifetime
- 2000-12-13 JP JP2001543172A patent/JP2003516191A/ja not_active Withdrawn
- 2000-12-13 WO PCT/US2000/033712 patent/WO2001041828A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
WO2001041828B1 (en) | 2001-11-15 |
CA2393438C (en) | 2008-12-09 |
ES2228647T3 (es) | 2005-04-16 |
EP1239896B1 (de) | 2004-10-13 |
US6479079B1 (en) | 2002-11-12 |
WO2001041828A1 (en) | 2001-06-14 |
CA2393438A1 (en) | 2001-06-14 |
EP1239896A1 (de) | 2002-09-18 |
DE60014966T2 (de) | 2006-03-09 |
JP2003516191A (ja) | 2003-05-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |