DE60014879D1 - Test zum nachweis der aktivität von phospho-n-acetylmuramyl-pentapeptid-translokase - Google Patents
Test zum nachweis der aktivität von phospho-n-acetylmuramyl-pentapeptid-translokaseInfo
- Publication number
- DE60014879D1 DE60014879D1 DE2000614879 DE60014879T DE60014879D1 DE 60014879 D1 DE60014879 D1 DE 60014879D1 DE 2000614879 DE2000614879 DE 2000614879 DE 60014879 T DE60014879 T DE 60014879T DE 60014879 D1 DE60014879 D1 DE 60014879D1
- Authority
- DE
- Germany
- Prior art keywords
- pentapeptide
- source
- acetylmuramyl
- propionate
- phospho
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000000694 effects Effects 0.000 title abstract 3
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 239000011541 reaction mixture Substances 0.000 abstract 2
- AASBXERNXVFUEJ-UHFFFAOYSA-N (2,5-dioxopyrrolidin-1-yl) propanoate Chemical group CCC(=O)ON1C(=O)CCC1=O AASBXERNXVFUEJ-UHFFFAOYSA-N 0.000 abstract 1
- XBDQKXXYIPTUBI-RVQWGROCSA-N 2,3-ditritiopropanoic acid Chemical group C(C(C[3H])[3H])(=O)O XBDQKXXYIPTUBI-RVQWGROCSA-N 0.000 abstract 1
- 108700023478 Phospho-N-acetylmuramoyl-pentapeptide-transferases Proteins 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 239000003599 detergent Substances 0.000 abstract 1
- UFPHFKCTOZIAFY-NTDVEAECSA-N ditrans,polycis-undecaprenyl phosphate Chemical compound CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/COP(O)(O)=O UFPHFKCTOZIAFY-NTDVEAECSA-N 0.000 abstract 1
- 238000006911 enzymatic reaction Methods 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 229910021645 metal ion Inorganic materials 0.000 abstract 1
- 230000020477 pH reduction Effects 0.000 abstract 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 1
- 230000002285 radioactive effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN9900013 | 1999-04-22 | ||
| WOPCT/IN99/00013 | 1999-04-22 | ||
| PCT/SE2000/000772 WO2000065087A1 (en) | 1999-04-22 | 2000-04-19 | Assay for detecting phospho-n-acetylmuramyl-pentapeptide translocase activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60014879D1 true DE60014879D1 (de) | 2004-11-18 |
| DE60014879T2 DE60014879T2 (de) | 2005-10-13 |
Family
ID=11076654
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60014879T Expired - Fee Related DE60014879T2 (de) | 1999-04-22 | 2000-04-19 | Test zum nachweis der aktivität von phospho-n-acetylmuramyl-pentapeptid-translokase |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6537770B1 (de) |
| EP (1) | EP1171631B1 (de) |
| JP (1) | JP2002542792A (de) |
| CN (1) | CN1157484C (de) |
| AT (1) | ATE279531T1 (de) |
| AU (1) | AU769842B2 (de) |
| CA (1) | CA2370469A1 (de) |
| DE (1) | DE60014879T2 (de) |
| HK (1) | HK1044027A1 (de) |
| WO (1) | WO2000065087A1 (de) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7214660B2 (en) | 2001-10-10 | 2007-05-08 | Neose Technologies, Inc. | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
| US7157277B2 (en) | 2001-11-28 | 2007-01-02 | Neose Technologies, Inc. | Factor VIII remodeling and glycoconjugation of Factor VIII |
| US7173003B2 (en) | 2001-10-10 | 2007-02-06 | Neose Technologies, Inc. | Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF |
| US7439043B2 (en) * | 2001-10-10 | 2008-10-21 | Neose Technologies, Inc. | Galactosyl nucleotide sugars |
| WO2004099231A2 (en) | 2003-04-09 | 2004-11-18 | Neose Technologies, Inc. | Glycopegylation methods and proteins/peptides produced by the methods |
| US7473680B2 (en) | 2001-11-28 | 2009-01-06 | Neose Technologies, Inc. | Remodeling and glycoconjugation of peptides |
| SE0104102D0 (sv) * | 2001-12-05 | 2001-12-05 | Astrazeneca Ab | New assay |
| BRPI0408358A (pt) | 2003-03-14 | 2006-03-21 | Neose Technologies Inc | polìmeros hidrossolúveis ramificados e seus conjugados |
| EP1613261A4 (de) | 2003-04-09 | 2011-01-26 | Novo Nordisk As | Intrazelluläre bildung von peptidkonjugaten |
| US8791070B2 (en) | 2003-04-09 | 2014-07-29 | Novo Nordisk A/S | Glycopegylated factor IX |
| WO2005012484A2 (en) | 2003-07-25 | 2005-02-10 | Neose Technologies, Inc. | Antibody-toxin conjugates |
| US20070254834A1 (en) | 2003-11-24 | 2007-11-01 | Defrees Shawn | Glycopegylated Erythropoietin |
| US20080305992A1 (en) | 2003-11-24 | 2008-12-11 | Neose Technologies, Inc. | Glycopegylated erythropoietin |
| US20060040856A1 (en) | 2003-12-03 | 2006-02-23 | Neose Technologies, Inc. | Glycopegylated factor IX |
| CA2552892C (en) | 2004-01-08 | 2014-08-05 | Neose Technologies, Inc. | O-linked glycosylation of peptides |
| WO2006010143A2 (en) | 2004-07-13 | 2006-01-26 | Neose Technologies, Inc. | Branched peg remodeling and glycosylation of glucagon-like peptide-1 [glp-1] |
| US8268967B2 (en) | 2004-09-10 | 2012-09-18 | Novo Nordisk A/S | Glycopegylated interferon α |
| EP1814573B1 (de) | 2004-10-29 | 2016-03-09 | ratiopharm GmbH | Remodellierung und glykopegylierung von fibroblasten-wachstumsfaktor (fgf) |
| ES2449195T3 (es) | 2005-01-10 | 2014-03-18 | Ratiopharm Gmbh | Factor estimulante de colonias de granulocitos glicopegilado |
| EP1871795A4 (de) | 2005-04-08 | 2010-03-31 | Biogenerix Ag | Zusammensetzungen und verfahren zur herstellung von glycosylierungsmutanten eines proteaseresistenten menschlichen wachstumshormons |
| US20080255026A1 (en) | 2005-05-25 | 2008-10-16 | Glycopegylated Factor 1X | Glycopegylated Factor Ix |
| US20070105755A1 (en) | 2005-10-26 | 2007-05-10 | Neose Technologies, Inc. | One pot desialylation and glycopegylation of therapeutic peptides |
| US20090048440A1 (en) | 2005-11-03 | 2009-02-19 | Neose Technologies, Inc. | Nucleotide Sugar Purification Using Membranes |
| CN101516388B (zh) | 2006-07-21 | 2012-10-31 | 诺和诺德公司 | 通过o-联糖基化序列的肽的糖基化 |
| WO2008057683A2 (en) | 2006-10-03 | 2008-05-15 | Novo Nordisk A/S | Methods for the purification of polypeptide conjugates |
| KR20100016160A (ko) | 2007-04-03 | 2010-02-12 | 바이오제너릭스 에이지 | 글리코페길화 ｇ―ｃｓｆ를 이용하는 치료 방법 |
| WO2008154639A2 (en) | 2007-06-12 | 2008-12-18 | Neose Technologies, Inc. | Improved process for the production of nucleotide sugars |
| ES2476690T3 (es) | 2008-02-27 | 2014-07-15 | Novo Nordisk A/S | Moléculas conjugadas del Factor VIII |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5861318A (en) * | 1994-11-16 | 1999-01-19 | Pharmacia & Upjohn Company | Scintillation proximity assay for N-acetylgalactosaminyltransferase activity |
| EP0890644A3 (de) * | 1997-07-10 | 1999-09-29 | Smithkline Beecham Corporation | MurA Gen vom Staphylococcus aureus das für DP-N-Acetylglucosamine enolpyruvyl transferase kodiert |
| US6156537A (en) * | 1997-08-12 | 2000-12-05 | Smithkline Beecham Corporation | Phospho-N-acetylmuramoyl-pentapeptide transferase of Streptococcus pneumoniae |
| WO2000010587A1 (en) * | 1998-08-20 | 2000-03-02 | Incara Pharmaceuticals Corp. | Analogs of udp-murnac peptides, assays and kits |
| US20030108969A1 (en) * | 2000-06-08 | 2003-06-12 | Desousa Sunita Maria | Assay for detection of translocase enzyme activity in drug screening |
-
2000
- 2000-04-19 WO PCT/SE2000/000772 patent/WO2000065087A1/en active IP Right Grant
- 2000-04-19 JP JP2000614421A patent/JP2002542792A/ja not_active Ceased
- 2000-04-19 CN CNB00806590XA patent/CN1157484C/zh not_active Expired - Fee Related
- 2000-04-19 AT AT00925833T patent/ATE279531T1/de not_active IP Right Cessation
- 2000-04-19 US US09/582,466 patent/US6537770B1/en not_active Expired - Fee Related
- 2000-04-19 AU AU44461/00A patent/AU769842B2/en not_active Ceased
- 2000-04-19 EP EP00925833A patent/EP1171631B1/de not_active Expired - Lifetime
- 2000-04-19 CA CA002370469A patent/CA2370469A1/en not_active Abandoned
- 2000-04-19 DE DE60014879T patent/DE60014879T2/de not_active Expired - Fee Related
-
2002
- 2002-08-01 HK HK02105678A patent/HK1044027A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1171631A1 (de) | 2002-01-16 |
| CN1157484C (zh) | 2004-07-14 |
| AU4446100A (en) | 2000-11-10 |
| AU769842B2 (en) | 2004-02-05 |
| EP1171631B1 (de) | 2004-10-13 |
| US6537770B1 (en) | 2003-03-25 |
| ATE279531T1 (de) | 2004-10-15 |
| JP2002542792A (ja) | 2002-12-17 |
| HK1044027A1 (en) | 2002-10-04 |
| DE60014879T2 (de) | 2005-10-13 |
| CA2370469A1 (en) | 2000-11-02 |
| CN1348503A (zh) | 2002-05-08 |
| WO2000065087A1 (en) | 2000-11-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |