SE0104102D0 - New assay - Google Patents

New assay

Info

Publication number
SE0104102D0
SE0104102D0 SE0104102A SE0104102A SE0104102D0 SE 0104102 D0 SE0104102 D0 SE 0104102D0 SE 0104102 A SE0104102 A SE 0104102A SE 0104102 A SE0104102 A SE 0104102A SE 0104102 D0 SE0104102 D0 SE 0104102D0
Authority
SE
Sweden
Prior art keywords
new assay
screening
transglycosylase
antagonists
bacteria
Prior art date
Application number
SE0104102A
Other languages
English (en)
Inventor
Sunita Maria Desousa
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0104102A priority Critical patent/SE0104102D0/sv
Publication of SE0104102D0 publication Critical patent/SE0104102D0/sv
Priority to US10/497,745 priority patent/US7354731B2/en
Priority to AU2002347337A priority patent/AU2002347337A1/en
Priority to EP02783272A priority patent/EP1458884A1/en
Priority to PCT/GB2002/005492 priority patent/WO2003048380A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SE0104102A 2001-12-05 2001-12-05 New assay SE0104102D0 (sv)

Priority Applications (5)

Application Number Priority Date Filing Date Title
SE0104102A SE0104102D0 (sv) 2001-12-05 2001-12-05 New assay
US10/497,745 US7354731B2 (en) 2001-12-05 2002-12-03 Method of screening for potential anti-bacterial agents
AU2002347337A AU2002347337A1 (en) 2001-12-05 2002-12-03 Method of screening forpotential anti-bacterial agents
EP02783272A EP1458884A1 (en) 2001-12-05 2002-12-03 Method of screening for potential anti-bacterial agents
PCT/GB2002/005492 WO2003048380A1 (en) 2001-12-05 2002-12-03 Method of screening forpotential anti-bacterial agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0104102A SE0104102D0 (sv) 2001-12-05 2001-12-05 New assay

Publications (1)

Publication Number Publication Date
SE0104102D0 true SE0104102D0 (sv) 2001-12-05

Family

ID=20286222

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0104102A SE0104102D0 (sv) 2001-12-05 2001-12-05 New assay

Country Status (5)

Country Link
US (1) US7354731B2 (sv)
EP (1) EP1458884A1 (sv)
AU (1) AU2002347337A1 (sv)
SE (1) SE0104102D0 (sv)
WO (1) WO2003048380A1 (sv)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008021367A2 (en) 2006-08-11 2008-02-21 President And Fellows Of Harvard College Moenomycin biosynthesis-related compositions and methods of use thereof
ES2329637B1 (es) 2006-11-10 2010-09-22 Universidad Autonoma De Madrid Procedimiento para la determinacion de la fragmentacion del adn en microorganismos.
EP2205074A4 (en) * 2007-10-04 2013-07-31 Harvard College ANALOGUES OF THE MOENOMYCIN, METHODS OF SYNTHESIS AND USES THEREOF
US20130149701A1 (en) * 2010-06-17 2013-06-13 Ying Zhang Methods of identifying therapeutic agents for treating persister and bacterial infection
ES2396820B1 (es) * 2011-07-26 2014-01-31 Universidad Autónoma de Madrid Método para evaluar la integridad de la pared celular bacteriana.
US9273084B2 (en) 2012-04-06 2016-03-01 President And Fellows Of Harvard College Moenomycin analogs, methods of synthesis, and uses thereof
US10106833B2 (en) 2012-04-06 2018-10-23 President And Fellows Of Harvard College Methods and compounds for identifying glycosyltransferase inhibitors
WO2013152279A1 (en) 2012-04-06 2013-10-10 President And Fellows Of Harvard College Chemoenzymatic methods for synthesizing moenomycin analogs

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4568649A (en) * 1983-02-22 1986-02-04 Immunex Corporation Immediate ligand detection assay
DE3483099D1 (de) 1984-03-15 1990-10-04 Immunex Corp Test zur sofortigen feststellung von liganden, testsatz und seine herstellung.
SE8804657D0 (sv) 1988-12-27 1988-12-27 Gerald Potter Colin Support structure for use in a proximity assey
SE9404072D0 (sv) 1994-11-24 1994-11-24 Astra Ab Novel polypeptides
JP2002501931A (ja) 1998-02-02 2002-01-22 プリンストン ユニバーシティ ＭｕｒＧの基質類似体、その製造方法およびそれを用いたアッセイ
CA2332796A1 (en) * 1998-05-15 1999-11-25 Astrazeneca Ab A scintillation proximity assay for the detection of peptidoglycan synthesis
US20010049117A1 (en) * 1998-08-20 2001-12-06 Helena R. Axelrod Analogs of udp-murnac peptides, assays, kits and related methods of their use
AU3615200A (en) * 1999-03-03 2000-09-21 Princeton University Bacterial transglycosylases: assays for monitoring the activity using lipid ii substrate analogs and methods for discovering new antibiotics
AU769842B2 (en) * 1999-04-22 2004-02-05 Astrazeneca Ab Assay for detecting phospho-N-acetylmuramyl-pentapeptide translocase activity
US6913895B1 (en) 1999-08-17 2005-07-05 Advanced Medicine East, Inc. Methods for assaying transglycosylase reactions, and for identifying inhibitors thereof
JP2003535598A (ja) * 2000-06-08 2003-12-02 アストラゼネカ アクチボラグ 薬剤スクリーニングにおけるトランスロカーゼ酵素活性検出のためのアッセイ

Also Published As

Publication number Publication date
US7354731B2 (en) 2008-04-08
EP1458884A1 (en) 2004-09-22
AU2002347337A1 (en) 2003-06-17
WO2003048380A1 (en) 2003-06-12
US20050106555A1 (en) 2005-05-19

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