DE60010665D1 - Mittel zur verwendung in der transplantation - Google Patents

Mittel zur verwendung in der transplantation

Info

Publication number
DE60010665D1
DE60010665D1 DE60010665T DE60010665T DE60010665D1 DE 60010665 D1 DE60010665 D1 DE 60010665D1 DE 60010665 T DE60010665 T DE 60010665T DE 60010665 T DE60010665 T DE 60010665T DE 60010665 D1 DE60010665 D1 DE 60010665D1
Authority
DE
Germany
Prior art keywords
group
lower alkyl
iodine
carbon atoms
positions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60010665T
Other languages
English (en)
Other versions
DE60010665T2 (de
Inventor
Lennart Moeller
Jan Bergman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OXYPHARMA STOCKHOLM AB
Original Assignee
OXYPHARMA STOCKHOLM AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by OXYPHARMA STOCKHOLM AB filed Critical OXYPHARMA STOCKHOLM AB
Publication of DE60010665D1 publication Critical patent/DE60010665D1/de
Application granted granted Critical
Publication of DE60010665T2 publication Critical patent/DE60010665T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Physiology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Surgery (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE60010665T 1999-02-25 2000-02-18 Mittel zur verwendung in der transplantation Expired - Fee Related DE60010665T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9900677 1999-02-25
SE9900677A SE516133C2 (sv) 1999-02-25 1999-02-25 Användning av vissa substituerade indolokinoxaliner för framställning av ett medel för skydd av vävnader, organ och celler vid transplantation
PCT/SE2000/000339 WO2000050039A1 (en) 1999-02-25 2000-02-18 Agent for use in transplantation

Publications (2)

Publication Number Publication Date
DE60010665D1 true DE60010665D1 (de) 2004-06-17
DE60010665T2 DE60010665T2 (de) 2005-05-19

Family

ID=20414629

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60010665T Expired - Fee Related DE60010665T2 (de) 1999-02-25 2000-02-18 Mittel zur verwendung in der transplantation

Country Status (11)

Country Link
US (1) US6472395B1 (de)
EP (1) EP1154772B1 (de)
JP (1) JP2002537338A (de)
CN (1) CN1151790C (de)
AT (1) ATE266406T1 (de)
AU (1) AU3339800A (de)
DE (1) DE60010665T2 (de)
ES (1) ES2220427T3 (de)
RU (1) RU2242975C2 (de)
SE (1) SE516133C2 (de)
WO (1) WO2000050039A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465466B1 (en) * 1995-12-22 2002-10-15 Leif J. I. Lundblad Uses of indolo-2 [2,3b] -quinoxalines

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5643921A (en) 1990-09-26 1997-07-01 E.R. Squibb & Sons, Inc. Cardiopulmonary bypass and organ transplant using a potassium channel activator
SE9302431D0 (sv) 1993-07-16 1993-07-16 Ab Astra Use of indenoindole compounds
US5859001A (en) 1996-01-11 1999-01-12 University Of Florida Research Foundation, Inc. Neuroprotective effects of polycyclic phenolic compounds
SE504289C2 (sv) * 1994-06-23 1996-12-23 Leif J I Lundblad Användning av vissa indolo-2,3b-kinoxaliner för framställning av ett läkemedel för inhibering av enzymet HIV-integras
SE504862C2 (sv) 1994-12-27 1997-05-20 Leif J I Lundblad Användning av vissa indolo-§2,3b¤-kinoxaliner för framställning av ett läkemedel för skydd av DNA i initieringsfasen och/eller promotionsfasen av karcinogenes och för förhindrande av oxidativ stress i patienter med sjukdomar relaterade till fria radikaler
US6635626B1 (en) * 1997-08-25 2003-10-21 Bristol-Myers Squibb Co. Imidazoquinoxaline protein tyrosine kinase inhibitors
CA2244554A1 (en) * 1998-07-30 2000-01-30 Vasogen Inc. Inhibition of graft versus host disease
US6333327B2 (en) * 2000-02-18 2001-12-25 Leif J. I. Lundblad Method for the treatment of Multiple Sclerosis

Also Published As

Publication number Publication date
EP1154772B1 (de) 2004-05-12
EP1154772A1 (de) 2001-11-21
ES2220427T3 (es) 2004-12-16
RU2242975C2 (ru) 2004-12-27
CN1151790C (zh) 2004-06-02
CN1341023A (zh) 2002-03-20
US6472395B1 (en) 2002-10-29
SE9900677D0 (sv) 1999-02-25
ATE266406T1 (de) 2004-05-15
SE516133C2 (sv) 2001-11-19
SE9900677L (sv) 2000-08-26
AU3339800A (en) 2000-09-14
JP2002537338A (ja) 2002-11-05
DE60010665T2 (de) 2005-05-19
WO2000050039A1 (en) 2000-08-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee