DE60006505D1 - Verfahren zu trennung fötaler zellen aus maternalem blut - Google Patents

Verfahren zu trennung fötaler zellen aus maternalem blut

Info

Publication number
DE60006505D1
DE60006505D1 DE60006505T DE60006505T DE60006505D1 DE 60006505 D1 DE60006505 D1 DE 60006505D1 DE 60006505 T DE60006505 T DE 60006505T DE 60006505 T DE60006505 T DE 60006505T DE 60006505 D1 DE60006505 D1 DE 60006505D1
Authority
DE
Germany
Prior art keywords
maternal blood
fetal cells
separating fetal
cells
blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60006505T
Other languages
English (en)
Other versions
DE60006505T2 (de
Inventor
Giammaria Sitar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE60006505D1 publication Critical patent/DE60006505D1/de
Publication of DE60006505T2 publication Critical patent/DE60006505T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Ecology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE60006505T 1999-03-30 2000-03-28 Verfahren zu trennung fötaler zellen aus maternalem blut Expired - Fee Related DE60006505T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI990652 1999-03-30
IT1999MI000652A IT1311989B1 (it) 1999-03-30 1999-03-30 Procedimento per isolare cellule fetali presenti nel sangue perifericomaterno.
PCT/EP2000/002718 WO2000060351A1 (en) 1999-03-30 2000-03-28 Method for the separation of fetal cells from the maternal peripheral blood

Publications (2)

Publication Number Publication Date
DE60006505D1 true DE60006505D1 (de) 2003-12-18
DE60006505T2 DE60006505T2 (de) 2004-08-05

Family

ID=11382509

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60006505T Expired - Fee Related DE60006505T2 (de) 1999-03-30 2000-03-28 Verfahren zu trennung fötaler zellen aus maternalem blut

Country Status (6)

Country Link
EP (1) EP1166108B1 (de)
AT (1) ATE254282T1 (de)
AU (1) AU3432400A (de)
DE (1) DE60006505T2 (de)
IT (1) IT1311989B1 (de)
WO (1) WO2000060351A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070131612A1 (en) * 2005-10-27 2007-06-14 Duffy Neil F Jr Cell separation method and apparatus
US8048678B2 (en) 2005-10-27 2011-11-01 Ecw Therapeutics, Inc. Cell separation method and apparatus
GB0616045D0 (en) * 2006-08-11 2006-09-20 Univ Bristol Blood cell separation
US20150299657A1 (en) * 2014-04-16 2015-10-22 General Electric Company Gamma stabilized dextran solutions and methods of use
GB201306810D0 (en) 2013-04-15 2013-05-29 Cells4Life Group Llp Methods of cell separation
GB2525202A (en) * 2014-04-15 2015-10-21 Cells4Life Group Llp Methods of cell separation
WO2016178931A1 (en) * 2015-05-01 2016-11-10 Mesotex, Inc. Process for separating nucleated cells from non-nucleated red blood cells
EP3440193A4 (de) * 2016-04-07 2020-03-04 Mesotex, Inc. Verfahren zur isolierung von nukleierten zellen und von populationen von nukleierten zellen und verwendungen davon

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1057254A (en) 1976-05-14 1979-06-26 Baxter Travenol Laboratories Disposable centrifugal blood processing system
FR2481614A1 (fr) 1980-05-05 1981-11-06 Inst Medical Sciences Procede, dispositif et appareil pour separer par centrifugation les plaquettes du sang
US4424132A (en) 1981-02-05 1984-01-03 Asahi Kasei Kogyo Kabushiki Kaisha Apparatus and method for separating blood components
US5489386A (en) * 1994-01-31 1996-02-06 Applied Imaging Density gradient medium for the separation of cells
US5432054A (en) * 1994-01-31 1995-07-11 Applied Imaging Method for separating rare cells from a population of cells
US5663051A (en) * 1994-08-31 1997-09-02 Activated Cell Therapy, Inc. Separation apparatus and method
US5662813A (en) * 1994-10-21 1997-09-02 Bioseparations, Inc. Method for separation of nucleated fetal erythrocytes from maternal blood samples
IT1295939B1 (it) 1997-10-31 1999-05-28 Giammaria Sitar Dispositivo e metodo per la separazione di cellule umane od animali aventi densita' diverse da dispersioni cellulari che le contengono

Also Published As

Publication number Publication date
EP1166108A1 (de) 2002-01-02
DE60006505T2 (de) 2004-08-05
IT1311989B1 (it) 2002-03-22
EP1166108B1 (de) 2003-11-12
ATE254282T1 (de) 2003-11-15
ITMI990652A1 (it) 2000-09-30
WO2000060351A1 (en) 2000-10-12
AU3432400A (en) 2000-10-23

Similar Documents

Publication Publication Date Title
Sekizawa et al. Apoptosis in fetal nucleated erythrocytes circulating in maternal blood
CN101715486B (zh) 用于非侵入性产前诊断的方法和装置
WO2001079851A8 (en) NON-INVASIVE PRENATAL DIAGNOSIS USING CD45-ve FETAL CELLS
DE69031984T2 (de) Ein nichtinvasives verfahren zur trennung und zum nachweis von fetaler dna
ATE254282T1 (de) Verfahren zu trennung fötaler zellen aus maternalem blut
EP2206772A3 (de) Verfahren zum Sammeln von Plazentastammzellen
DE69430365D1 (de) Isolierung fötaler erythrozyten
DE69001453D1 (de) Vorrichtung zur trennung von mononuklearen zellen aus blut und verfahren zu ihrer herstellung und verwendung.
WO2001081626A3 (en) Methods for clinical diagnosis
DK0974056T3 (da) Prænatale in vitro-diagnostiske fremgangsmåder
EP0944829B1 (de) Selektives verfahren zur lyse von zellen
Kwon et al. A high yield of fetal nucleated red blood cells isolated using optimal osmolality and a double‐density gradient system
Voullaire et al. Fetal nucleated red blood cells from CVS washings: an aid to development of first trimester non‐invasive prenatal diagnosis
Hamada et al. Mid‐trimester fetal sex determination from maternal peripheral blood by fluorescence in situ hybridization without enrichment of fetal cells
ATE228026T1 (de) Methode zur erreicherung von populationen seltener zellen
WO2001077316A3 (en) Method of nucleic acid recovery
Beckman et al. The relation between human placental alkaline phosphatase types and some perinatal factors
EP0028842A3 (de) Medium für die Abtrennung von Leukozyten aus menschlichem Blut
NZ337700A (en) Prenatal diagnostic methods by separating maternal from fetal blood using conventional chromatographis techniques followed by typing fetal blood for genatic defects
Kulozik et al. Fetal cells in the maternal circulation: detection by direct AFP-immunofluorescence
Landaw et al. 192 DECREASED SURVIVAL AND ALTERED MEMBRANE PROPERTIES OF RED BLOOD CELLS (RBC) IN THE NEWBORN RAT
CN115094033A (zh) 一种分离胎儿红细胞的方法及装置
Coataa et al. Fetal CD34+ Cell Culture and Identification from Maternal Blood
Yang et al. Prenatal fetal sex determination from maternal peripheral blood using polymerase chain reaction
Kugler et al. 190 EFFECT OF CHEMICAL SYMPATHECTOMY ON MYOCARDIAL CELL DIVISION IN THE RAT

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee