DE60001492D1 - Pharmazeutische aerosolformulierung - Google Patents

Pharmazeutische aerosolformulierung

Info

Publication number
DE60001492D1
DE60001492D1 DE60001492T DE60001492T DE60001492D1 DE 60001492 D1 DE60001492 D1 DE 60001492D1 DE 60001492 T DE60001492 T DE 60001492T DE 60001492 T DE60001492 T DE 60001492T DE 60001492 D1 DE60001492 D1 DE 60001492D1
Authority
DE
Germany
Prior art keywords
pharmaceutical aerosol
formulations
aerosol formulation
relates
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60001492T
Other languages
English (en)
Other versions
DE60001492T2 (de
Inventor
Isabelle Bonvoisin
Christophe Laroche
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9921289.6A external-priority patent/GB9921289D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of DE60001492D1 publication Critical patent/DE60001492D1/de
Application granted granted Critical
Publication of DE60001492T2 publication Critical patent/DE60001492T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
DE60001492T 1999-04-14 2000-04-13 Pharmazeutische aerosolformulierung Expired - Fee Related DE60001492T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
BH12699 1999-04-14
GBGB9921289.6A GB9921289D0 (en) 1999-09-10 1999-09-10 Pharmaceutical aerosol formulation
PCT/GB2000/001418 WO2000061108A1 (en) 1999-04-14 2000-04-13 Pharmaceutical aerosol formulation

Publications (2)

Publication Number Publication Date
DE60001492D1 true DE60001492D1 (de) 2003-04-03
DE60001492T2 DE60001492T2 (de) 2003-12-18

Family

ID=25663377

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60001492T Expired - Fee Related DE60001492T2 (de) 1999-04-14 2000-04-13 Pharmazeutische aerosolformulierung

Country Status (10)

Country Link
US (1) US7090831B1 (de)
EP (1) EP1169019B1 (de)
JP (1) JP2002541183A (de)
AT (1) ATE233084T1 (de)
AU (1) AU4417500A (de)
DE (1) DE60001492T2 (de)
DK (1) DK1169019T3 (de)
ES (1) ES2193069T3 (de)
PT (1) PT1169019E (de)
WO (1) WO2000061108A1 (de)

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US20080064613A1 (en) * 2006-09-11 2008-03-13 M-I Llc Dispersant coated weighting agents
ATE446085T1 (de) 2000-11-30 2009-11-15 Vectura Ltd Partikel zur verwendung in einer pharmazeutischen zusammensetzung
DK2283817T3 (en) 2000-11-30 2016-09-05 Vectura Ltd Process for preparing particles for use in a pharmaceutical composition
WO2002051483A1 (en) * 2000-12-22 2002-07-04 Glaxo Group Limited Metered dose inhaler for salmeterol xinafoate
MXPA04002401A (es) * 2001-09-14 2004-05-31 Boehringer Ingelheim Pharma Nuevos medicamentos para inhalacion.
JP2006507036A (ja) * 2002-08-14 2006-03-02 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 薬剤粒子のコーティング方法
PE20040950A1 (es) 2003-02-14 2005-01-01 Theravance Inc DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
KR20060012628A (ko) * 2003-05-19 2006-02-08 백스터 인터내셔널 인코포레이티드 하나 이상의 표면 변형제로 피복시킨 항경련제 또는면역억제제를 포함하는 고형 입자
GB0321607D0 (en) 2003-09-15 2003-10-15 Vectura Ltd Manufacture of pharmaceutical compositions
WO2005051511A1 (ja) * 2003-11-28 2005-06-09 Mitsubishi Chemical Corporation 有機化合物微粒子の製造方法
TWI341836B (en) 2004-03-11 2011-05-11 Theravance Inc Biphenyl compounds useful as muscarinic receptor antagonists
US7569586B2 (en) 2004-08-16 2009-08-04 Theravance, Inc. Compounds having β2 adrenergic receptor agonist and muscarinic receptor antagonist activity
EP2213165A1 (de) * 2007-11-27 2010-08-04 Erc Technology Inc. Neuartige zusammensetzung mit einem ozonisierten tensid
WO2010091198A1 (en) 2009-02-06 2010-08-12 University Of Southern California Therapeutic compositions comprising monoterpenes
CA2763941A1 (en) 2009-05-29 2010-12-02 Pearl Therapeutics, Inc. Compositions, methods & systems for respiratory delivery of two or more active agents
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
DK2453894T3 (en) 2009-07-15 2016-01-25 Theravance Biopharma R&D Ip Llc Crystalline free base of a biphenyl compound
EP2542082B8 (de) 2010-03-03 2020-06-17 Neonc Technologies Inc. PHARMAZEUTISCHE ZUSAMMENSETZUNGEN MIT (S)-Perillylalkohol
US20160038600A1 (en) 2012-08-03 2016-02-11 Neonc Technologies Inc. Pharmaceutical compositions comprising poh derivatives
CN110464718A (zh) 2010-08-27 2019-11-19 尼昂克技术公司 包含poh衍生物的药物组合物
DK2651864T3 (en) 2010-12-17 2016-09-05 Neonc Tech Inc Methods and devices for use of isoperillylalkohol
RU2629085C2 (ru) 2011-10-11 2017-08-24 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Кристаллические микрочастицы бета-агониста, покрытые жирной кислотой
BR112015022784B1 (pt) 2013-03-15 2023-02-14 Pearl Therapeutics, Inc Método de condicionamento de material cristalino micronizado e sistemas de condicionamento
CA2902403C (en) 2013-03-15 2021-06-01 Verona Pharma Plc Pde3/pde4 inhibitor/muscarinic receptor antagonist combination
DE102013021718B4 (de) * 2013-12-20 2017-03-02 Gerresheimer Regensburg Gmbh Kapsel zur Verwendung als Reservoir für eine pharmazeutische, vorzugsweise pulverförmige Zubereitung in einem Inhalator sowie Inhalator dafür
PT3231444T (pt) 2014-05-12 2020-03-05 Verona Pharma Plc Novo tratamento
KR20170131405A (ko) 2015-02-12 2017-11-29 네온씨 테크놀로지스, 아이엔씨. 페릴릴 알코올 유도체를 포함하는 의약 조성물
JP7144411B2 (ja) 2016-11-30 2022-09-29 ネオンク テクノロジーズ インク． ペリリルアルコール－３－ブロモピルベート複合体及びがんの治療方法
US20210228498A1 (en) 2018-02-08 2021-07-29 Neonc Technologies, Inc. Methods of permeabilizing the blood brain barrier

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ZW6584A1 (en) 1983-04-18 1985-04-17 Glaxo Group Ltd Phenethanolamine derivatives
JP2765700B2 (ja) 1986-08-11 1998-06-18 イノベータ・バイオメド・リミテツド マイクロカプセルを含有する医薬調合物
GB8921222D0 (en) 1989-09-20 1989-11-08 Riker Laboratories Inc Medicinal aerosol formulations
WO1991016882A1 (en) 1990-05-08 1991-11-14 Liposome Technology, Inc. Direct spray-dried drug/lipid powder composition
GB9024365D0 (en) * 1990-11-09 1991-01-02 Glaxo Group Ltd Medicaments
GB9024366D0 (en) * 1990-11-09 1991-01-02 Glaxo Group Ltd Medicaments
GB9026005D0 (en) 1990-11-29 1991-01-16 Glaxo Group Ltd Drug material suitable for micronisation
ATE171865T1 (de) 1991-12-12 1998-10-15 Glaxo Group Ltd Arzneimittel
IL104068A (en) 1991-12-12 1998-10-30 Glaxo Group Ltd Pharmaceutical preparations in a spray without surfactant containing 1, 1, 1, 2 tetrafluoroethane or 1,1,2,3,3 petafluor N propane as propellant
SG42375A1 (en) 1991-12-31 2001-04-17 Solvay Medicinal aerosol formulation
MX9304585A (es) 1992-07-31 1994-03-31 Glaxo Group Ltd Formulacion farmaceutica en aerosol, lata adecuada para liberar la formulacion e inhalador de dosis dosificada que comprende la lata.
EP0655237A1 (de) * 1993-11-27 1995-05-31 Hoechst Aktiengesellschaft Medizinische Aerosolformulierung
GB9419536D0 (en) * 1994-09-28 1994-11-16 Glaxo Inc Medicaments
JPH08151322A (ja) * 1994-09-30 1996-06-11 Takeda Chem Ind Ltd 経口徐放剤
GB9425160D0 (en) * 1994-12-10 1995-02-08 Glaxo Group Ltd Medicaments
GB9606188D0 (en) 1996-03-23 1996-05-29 Danbiosyst Uk Pollysaccharide microspheres for the pulmonary delivery of drugs
AU5806998A (en) 1996-12-31 1998-07-31 Inhale Therapeutic Systems Processes for spray drying solutions of hydrophobic drugs with hydrophilic excipients and compositions prepared by such processes
EP1073417B1 (de) * 1998-04-18 2002-12-04 Glaxo Group Limited Pharmazeutische aerosolformulierung
GB9828721D0 (en) 1998-12-24 1999-02-17 Glaxo Group Ltd Novel apparatus and process

Also Published As

Publication number Publication date
AU4417500A (en) 2000-11-14
PT1169019E (pt) 2003-07-31
EP1169019B1 (de) 2003-02-26
EP1169019A1 (de) 2002-01-09
ATE233084T1 (de) 2003-03-15
JP2002541183A (ja) 2002-12-03
US7090831B1 (en) 2006-08-15
ES2193069T3 (es) 2003-11-01
WO2000061108A1 (en) 2000-10-19
DK1169019T3 (da) 2003-06-02
DE60001492T2 (de) 2003-12-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee