DE59809832D1 - Fliessfähige getrocknete Partikel - Google Patents

Fliessfähige getrocknete Partikel

Info

Publication number
DE59809832D1
DE59809832D1 DE59809832T DE59809832T DE59809832D1 DE 59809832 D1 DE59809832 D1 DE 59809832D1 DE 59809832 T DE59809832 T DE 59809832T DE 59809832 T DE59809832 T DE 59809832T DE 59809832 D1 DE59809832 D1 DE 59809832D1
Authority
DE
Germany
Prior art keywords
dried particles
flowable
flowable dried
particles
dried
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE59809832T
Other languages
German (de)
English (en)
Inventor
Jean-Claude Tritsch
Johann Ulm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of DE59809832D1 publication Critical patent/DE59809832D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/501—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Glanulating (AREA)
  • Formation And Processing Of Food Products (AREA)
DE59809832T 1997-02-28 1998-02-20 Fliessfähige getrocknete Partikel Expired - Lifetime DE59809832D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH48297 1997-02-28

Publications (1)

Publication Number Publication Date
DE59809832D1 true DE59809832D1 (de) 2003-11-13

Family

ID=4188018

Family Applications (1)

Application Number Title Priority Date Filing Date
DE59809832T Expired - Lifetime DE59809832D1 (de) 1997-02-28 1998-02-20 Fliessfähige getrocknete Partikel

Country Status (15)

Country Link
US (1) US6030645A (enExample)
EP (1) EP0867177B1 (enExample)
JP (1) JP4494539B2 (enExample)
KR (1) KR19980071798A (enExample)
CN (1) CN1146405C (enExample)
AU (1) AU734530B2 (enExample)
BR (1) BR9800788A (enExample)
CA (1) CA2229351C (enExample)
DE (1) DE59809832D1 (enExample)
DK (1) DK0867177T3 (enExample)
ES (1) ES2206770T3 (enExample)
ID (1) ID19841A (enExample)
NO (1) NO320488B1 (enExample)
PH (1) PH11998000410B1 (enExample)
TW (1) TW505528B (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6395303B1 (en) * 1996-06-10 2002-05-28 Edward Mendell Co., Inc. Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose
JP2000509079A (ja) 1996-04-11 2000-07-18 ロダース・クロックラーン・ビー・ブイ 自由流動性脂肪組成物
JP4027535B2 (ja) * 1998-05-26 2007-12-26 エーザイ・アール・アンド・ディー・マネジメント株式会社 脂溶性薬物を含有した粉末
JP2002517600A (ja) * 1998-06-08 2002-06-18 ザ ユニヴァーシティ オブ ジョージア リサーチファウンデーション， インク． 使用済み揚油の再生方法及びその処理剤
AR020343A1 (es) * 1998-11-24 2002-05-08 Steigerwald Arzlneimittelwerk Metodo para producir farmacos que contienen extractos de plantas en una forma solida de aplicacion.
ATE257332T1 (de) * 1999-03-18 2004-01-15 Bristol Myers Squibb Co Vitamin formulierung für kardiovaskuläre gesundheit
US6914073B2 (en) * 1999-03-18 2005-07-05 Bristol Myers Squibb Company Vitamin formulation for cardiovascular health
US6444227B1 (en) 1999-08-05 2002-09-03 Roche Vitamins Inc. Process for preparing fat soluble beadlets
US7056531B1 (en) 2000-05-04 2006-06-06 Nature's Way Products, Inc. Sustained release compositions for orally administered substances and methods
AT414205B (de) * 2000-06-20 2006-10-15 Vis Vitalis Lizenz & Handels Verfahren zur herstellung von ungesättigtem fettsäure-trockenkonzentrat
JP2002037727A (ja) * 2000-07-26 2002-02-06 Eisai Co Ltd 脂溶性薬物を配合した速崩性固形製剤及びその製造方法
US6773733B2 (en) * 2001-03-26 2004-08-10 Loders Croklaan Usa Llc Structured particulate systems
US6753017B2 (en) * 2001-11-07 2004-06-22 Jrs Pharma Lp Process for preparing dry extracts
US7179488B2 (en) * 2001-11-29 2007-02-20 Bob Sherwood Process for co-spray drying liquid herbal extracts with dry silicified MCC
WO2003092406A1 (en) * 2002-05-02 2003-11-13 Volker Kuellmer Coated, agglomerated phytochemicals
GB0310673D0 (en) 2003-05-09 2003-06-11 Givaudan Sa Alginate matrix particles
US7198653B2 (en) 2003-07-31 2007-04-03 Delavau Llc Calcium carbonate granulation
WO2005041869A2 (en) * 2003-10-24 2005-05-12 Josef Rettenmaier & Soehne Gmbh & Co., Kg Process for co-spray drying agents with dry silicified mcc
US20050214367A1 (en) * 2004-03-22 2005-09-29 Volker Kuellmer Processes for making coated phytochemicals and tocopherols and products formed therefrom
EP1738738B1 (en) * 2005-06-04 2012-07-11 Cognis IP Management GmbH Microcapsules
US20090208576A1 (en) * 2006-03-31 2009-08-20 Gandhi Anilkumar S Orally Disintegrating Tablets
EP2026664B1 (en) * 2006-05-19 2014-09-10 Firmenich S.A. One step spray-drying process
US9138414B1 (en) 2006-09-15 2015-09-22 Delavau Llc Calcium supplement having enhanced absorption
US7282225B1 (en) 2006-09-27 2007-10-16 Occular Technologies, Inc. Composition and methods for improving retinal health
EP2101738A2 (en) * 2006-12-21 2009-09-23 Mallinckrodt Inc. Composition of and method for preparing orally disintegrating tablets
EP2118082B1 (en) 2007-02-23 2014-10-01 Gilead Sciences, Inc. Modulators of pharmacokinetic properties of therapeutics
AP3089A (en) 2008-05-02 2015-01-31 Gilead Sciences Inc The use of solid carrier particles to improve the processability of a pharmaceutical agent
GB201102557D0 (en) * 2011-02-14 2011-03-30 Univ Nottingham Oil bodies
JP5791304B2 (ja) * 2011-02-17 2015-10-07 アサヒフードアンドヘルスケア株式会社 ビタミンｃ類の反応抑制方法、及び、ビタミンｃ類を含む食品等製品
WO2018109059A1 (en) * 2016-12-15 2018-06-21 Dsm Ip Assets B.V. Blend formulation comprising silicate and microbial and / or plant cells comprising a polyunsaturated fatty acid having at least 20 carbon atoms (lc-pufa)
AU2018344460B2 (en) * 2017-10-05 2023-11-30 Purac Biochem B.V. Lactate powder and method for the preparation thereof
CN109221869A (zh) * 2018-10-25 2019-01-18 广州市炜鑫生物科技有限公司 一种复合酵素纤维素固体饮料及其制备方法
CN110917071B (zh) * 2019-12-23 2022-11-08 万华化学集团股份有限公司 核壳结构柔珠、其制备方法及包括其的个人护理用品
CN117122069A (zh) * 2022-05-19 2023-11-28 仙乐健康科技股份有限公司 一种颗粒和包含所述颗粒的酸性食品

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2756177A (en) * 1953-03-09 1956-07-24 Hoffmann La Roche Process for making fat-soluble vitamin active powder
US2858215A (en) * 1956-07-02 1958-10-28 Barnett Lab Inc Process of preparing vitamin oils in particle form
US3247064A (en) * 1962-03-30 1966-04-19 Shionogi & Co Multivitamin tablet stabilized with porous silica
GB1142147A (en) * 1965-05-28 1969-02-05 Glaxo Lab Ltd A process for making free-flowing gel particles
DE3135329A1 (de) * 1981-09-05 1983-03-24 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von trockenpulvern oxidationsempfindlicher substanzen
US4603143A (en) * 1983-05-02 1986-07-29 Basf Corporation Free-flowing, high density, fat soluble vitamin powders with improved stability
US4670247A (en) * 1983-07-05 1987-06-02 Hoffman-Laroche Inc. Process for preparing fat-soluble vitamin active beadlets
US4780309A (en) * 1987-06-16 1988-10-25 Warner-Lambert Company Edible aerosol foam compositions and method of preparing same
US4906478A (en) * 1988-12-12 1990-03-06 Valentine Enterprises, Inc. Simethicone/calcium silicate composition
FR2681248B1 (fr) * 1991-09-13 1995-04-28 Oreal Composition pour un traitement cosmetique et/ou pharmaceutique de longue duree des couches superieures de l'epiderme par une application topique sur la peau.
US5837790A (en) * 1994-10-24 1998-11-17 Amcol International Corporation Precipitation polymerization process for producing an oil adsorbent polymer capable of entrapping solid particles and liquids and the product thereof

Also Published As

Publication number Publication date
CA2229351C (en) 2009-04-14
JP4494539B2 (ja) 2010-06-30
EP0867177A1 (de) 1998-09-30
TW505528B (en) 2002-10-11
DK0867177T3 (da) 2004-01-26
NO980840D0 (no) 1998-02-27
ID19841A (id) 1998-08-06
PH11998000410B1 (enExample) 2002-07-05
US6030645A (en) 2000-02-29
NO980840L (no) 1998-08-31
AU5638498A (en) 1998-09-03
CN1146405C (zh) 2004-04-21
CA2229351A1 (en) 1998-08-28
EP0867177B1 (de) 2003-10-08
CN1194827A (zh) 1998-10-07
MX9801512A (enExample) 1999-04-01
NO320488B1 (no) 2005-12-12
KR19980071798A (ko) 1998-10-26
MX205481B (enExample) 2001-12-13
AU734530B2 (en) 2001-06-14
BR9800788A (pt) 2000-04-04
JPH10245348A (ja) 1998-09-14
ES2206770T3 (es) 2004-05-16

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: DSM IP ASSETS B.V., TE HEERLEN, NL