DE59711557D1 - Automatisierte Vorrichtung und Verfahren zum Messen und Bestimmen von Molekülen oder Teilen davon - Google Patents

Automatisierte Vorrichtung und Verfahren zum Messen und Bestimmen von Molekülen oder Teilen davon

Info

Publication number
DE59711557D1
DE59711557D1 DE59711557T DE59711557T DE59711557D1 DE 59711557 D1 DE59711557 D1 DE 59711557D1 DE 59711557 T DE59711557 T DE 59711557T DE 59711557 T DE59711557 T DE 59711557T DE 59711557 D1 DE59711557 D1 DE 59711557D1
Authority
DE
Germany
Prior art keywords
measuring
parts
automated device
determining molecules
molecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE59711557T
Other languages
English (en)
Inventor
Walter Schubert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MPB Meltec Patent und Beteiligungs GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE59711557D1 publication Critical patent/DE59711557D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1002—Reagent dispensers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/113332—Automated chemical analysis with conveyance of sample along a test line in a container or rack
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/113332—Automated chemical analysis with conveyance of sample along a test line in a container or rack
    • Y10T436/114165—Automated chemical analysis with conveyance of sample along a test line in a container or rack with step of insertion or removal from test line
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/113332—Automated chemical analysis with conveyance of sample along a test line in a container or rack
    • Y10T436/114998—Automated chemical analysis with conveyance of sample along a test line in a container or rack with treatment or replacement of aspirator element [e.g., cleaning, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/115831—Condition or time responsive
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Plasma & Fusion (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Robotics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
DE59711557T 1996-05-29 1997-05-15 Automatisierte Vorrichtung und Verfahren zum Messen und Bestimmen von Molekülen oder Teilen davon Expired - Lifetime DE59711557D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19621364 1996-05-29
DE19709348A DE19709348C2 (de) 1996-05-29 1997-03-07 Automatisches Multi-Epitop-Ligand-Kartierungsverfahren

Publications (1)

Publication Number Publication Date
DE59711557D1 true DE59711557D1 (de) 2004-06-03

Family

ID=7795485

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19709348A Expired - Fee Related DE19709348C2 (de) 1996-05-29 1997-03-07 Automatisches Multi-Epitop-Ligand-Kartierungsverfahren
DE59711557T Expired - Lifetime DE59711557D1 (de) 1996-05-29 1997-05-15 Automatisierte Vorrichtung und Verfahren zum Messen und Bestimmen von Molekülen oder Teilen davon

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE19709348A Expired - Fee Related DE19709348C2 (de) 1996-05-29 1997-03-07 Automatisches Multi-Epitop-Ligand-Kartierungsverfahren

Country Status (2)

Country Link
US (1) US6150173A (de)
DE (2) DE19709348C2 (de)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19709348C2 (de) * 1996-05-29 1999-07-01 Schubert Walter Dr Md Automatisches Multi-Epitop-Ligand-Kartierungsverfahren
US20020159919A1 (en) * 1998-01-09 2002-10-31 Carl Churchill Method and apparatus for high-speed microfluidic dispensing using text file control
US7470547B2 (en) 2003-07-31 2008-12-30 Biodot, Inc. Methods and systems for dispensing sub-microfluidic drops
DE19913922C2 (de) * 1998-06-15 2002-10-24 Steag Rtp Systems Gmbh Verfahren zum Bestimmen von Parameterverteilungen von Substrateigenschaften
DE19846466A1 (de) * 1998-10-08 2000-04-27 Ghs Gesundheits Service Ag Analyseverfahren zur simultanen Bestimmung von Parametern aus unterschiedlichen Medien
DE19916749B4 (de) * 1999-04-14 2004-02-12 Carl Zeiss Jena Gmbh Verfahren zur Untersuchung von Proben
DE19919539C5 (de) * 1999-04-29 2004-12-09 Gerhard Lewandovski Verfahren zur Messung der Aktivität einer biologisch wirksamen Substanz in einem histologischen Präparat
DE19932958C2 (de) * 1999-07-14 2003-08-07 Walter Schubert Vorrichtung zur Bindung von Molekülen, Molekülgruppen, Molekülteilen und/oder Zellen
DE19946525A1 (de) * 1999-09-28 2001-05-03 Fraunhofer Ges Forschung Vorrichtung zur Aufnahme und Abgabe kleinster Flüssigkeitsmengen
DE10014708A1 (de) * 2000-03-24 2001-10-31 Walter Schubert Verfahren zur Identifizierung und Anreicherung von zellspezifischen Zielstrukturen
DE10014685B4 (de) * 2000-03-24 2004-07-01 Schubert, Walter, Dr. Verfahren zur Identifizierung von zellspezifischen Zielstrukturen
US6692972B1 (en) * 2000-08-24 2004-02-17 University Of Chicago Device for producing microscopic arrays of molecules, a method for producing microscopic arrays of molecules
EP1324829B1 (de) * 2000-08-30 2007-12-26 Biodot, Inc. Verfahren zur hochgeschwindigkeits-mikrofluidischen-dispergierung
DE10043470B4 (de) * 2000-09-04 2006-01-19 Mpb Meltec Patent- Und Beteiligungsgesellschaft Mbh Verfahren zur Identifizierung von zellspezifischen Proteinen
DE10128552B4 (de) * 2001-06-13 2015-01-22 Jens Stockhausen Verfahren zur Zellanalyse und Zellanalyseeinrichtung
US20030087454A1 (en) * 2001-10-26 2003-05-08 Schultz Gary A Method and device for chemical analysis
US7139415B2 (en) * 2001-12-05 2006-11-21 The Regents Of The University Of California Robotic microscopy systems
AU2002358657A1 (en) * 2001-12-10 2003-06-23 Evotec Oai Ag Method for determining the influence of non-physiological compounds the derivatives and decomposition products thereof on organisms organs and cells
EP1331473B1 (de) * 2002-01-22 2005-04-06 MPB MelTec Patent- und Beteiligungsgesellschaft mbH Verfahren und Vorrichtung für die Probenvorbereitung zur Analyse von biologischen Proben
US7776195B2 (en) * 2002-05-28 2010-08-17 Autogenomics, Inc. Integrated sample processing platform
WO2003100380A2 (en) 2002-05-28 2003-12-04 Autogenomics, Inc. Integrated sample processing platform
AU2003237340A1 (en) * 2002-05-28 2003-12-12 Autogenomics, Inc. Level-controlled pipette for automated analytic devices
US20060223065A1 (en) 2003-09-30 2006-10-05 Evotec Neuroscience Gmbh Diagnostic and therapeutic use of a sulfotransferase for neurodegenerative diseases
KR100624458B1 (ko) * 2005-01-17 2006-09-19 삼성전자주식회사 휴대용 원심분리기
WO2006100033A1 (en) * 2005-03-21 2006-09-28 Mpb Meltec Patent- Und Beteiligungsgesellschaft Mbh Method for identifying cell-specific protein combination patterns
ATE530667T1 (de) 2005-05-27 2011-11-15 Evotec Neurosciences Gmbh Kcnn3 als diagnostisches und therapeutisches target für alzheimer-krankheit
WO2006128879A1 (en) 2005-05-30 2006-12-07 Takeda Pharmaceutical Company Limited Diagnostic and therapeutic target prkx proteins for neurodegenerative diseases
US20090133135A1 (en) 2005-06-01 2009-05-21 Evotec Neurosciences Gmbh Diagnostic and Therapeutic Target SLC39A11 Proteins for Neurodegenerative Diseases
CA2623405C (en) 2005-09-20 2014-11-25 Immunivest Corporation Methods and composition to generate unique sequence dna probes labeling of dna probes and the use of these probes
US9134237B2 (en) * 2005-09-20 2015-09-15 Janssen Diagnotics, LLC High sensitivity multiparameter method for rare event analysis in a biological sample
US20070191675A1 (en) * 2006-02-13 2007-08-16 Joel Gerardo Diaz Sanchez Actinic light colposcope and method to detect lesions in the lower female genital tract produced by human papilloma virus using an actinic light colposcope
DE102006010907A1 (de) * 2006-03-09 2007-09-20 Mpb Meltec Patent- Und Beteiligungsgesellschaft Mbh Verfahren zur Bestimmung von Molekülen oder Molekülteilen in biologischen Proben
DE102006063050B8 (de) * 2006-03-13 2019-12-05 ToposNomos Ltd. Vorrichtung und Verfahren zur Erkennung und Identifizierung von Zielstrukturen
DE102006012613B4 (de) * 2006-03-17 2010-01-14 Mpb Meltec Patent- Und Beteiligungsgesellschaft Mbh Verfahren zur Bestimmung der therapeutischen Wirksamkeit von Substanzen
US20080032321A1 (en) * 2006-08-07 2008-02-07 General Electric Company System and methods for analyzing images of tissue samples
US8131476B2 (en) * 2006-08-07 2012-03-06 General Electric Company System and method for co-registering multi-channel images of a tissue micro array
US8060348B2 (en) * 2006-08-07 2011-11-15 General Electric Company Systems for analyzing tissue samples
DE102006040513A1 (de) * 2006-08-30 2008-03-27 Skinsystec Gmbh Verfahren zur quantitativen Bestimmung der Kolokalisation von Molekülmarkern in Gewebeschnitten
US7629125B2 (en) * 2006-11-16 2009-12-08 General Electric Company Sequential analysis of biological samples
US7741045B2 (en) * 2006-11-16 2010-06-22 General Electric Company Sequential analysis of biological samples
US9201063B2 (en) * 2006-11-16 2015-12-01 General Electric Company Sequential analysis of biological samples
EP2136911A2 (de) 2007-01-19 2009-12-30 Biodot, Inc. Systeme und verfahren für hochgeschwindigkeitsarraydruck und -hybridisierung
EP2053397A1 (de) 2007-10-25 2009-04-29 EVOTEC Neurosciences GmbH PPM1E-Proteine und Nukleinsäuren als Targets für neurodegenerative Erkrankungen
US20090253163A1 (en) * 2008-04-02 2009-10-08 General Electric Company Iterative staining of biological samples
US9602777B2 (en) 2008-04-25 2017-03-21 Roche Diagnostics Hematology, Inc. Systems and methods for analyzing body fluids
WO2012030313A1 (en) 2008-04-25 2012-03-08 James Winkelman Method of determining a complete blood count and a white blood cell differential count
DE102008053270A1 (de) 2008-10-27 2010-05-12 Medizinische Hochschule Hannover Vorrichtung und Verfahren zur Analyse von Zellen
DE102008062372B3 (de) 2008-12-17 2010-06-17 Medizinische Hochschule Hannover Nachweiskonjugat und Verfahren zur Analyse
WO2010099918A1 (en) * 2009-03-06 2010-09-10 Klaus Tschira Stiftung Ggmbh Pharmaceutical composition and method for identifying a cancerous and/or an inflammatory disease in a patient
EP3299812B1 (de) 2009-04-13 2020-03-11 University of Washington Detektionsverfahren und -vorrichtung seltener partikel
US20110058728A1 (en) 2009-08-28 2011-03-10 Petra Perner Device and Method for Automatic Detection of Dynamic Processes of Cells in Cell Samples
US9677125B2 (en) * 2009-10-21 2017-06-13 General Electric Company Detection of plurality of targets in biological samples
JP5978220B2 (ja) 2010-10-29 2016-08-24 プレジデント アンド フェローズ オブ ハーバード カレッジ 核酸ナノ構造バーコードプローブ
EP2665557B1 (de) 2011-01-21 2020-01-01 Biodot, Inc. Piezoelektrischer spender mit einem länglichen wandler und einem auswechselbaren kapillarrohr
CA2893590C (en) 2012-12-14 2023-10-10 The J. David Gladstone Institutes Automated robotic microscopy systems
DE102013202183A1 (de) * 2013-02-11 2014-08-14 Siemens Aktiengesellschaft Verfahren zum Anfärben von Zellproben für die Mikroskopie
EP3017308A4 (de) 2013-07-05 2017-04-26 University Of Washington Through Its Center For Commercialization Verfahren, zusammensetzungen und systeme für mikrofluidische assays
KR20160039229A (ko) 2013-07-30 2016-04-08 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 정량적 dna-기반 영상화 및 초해상도 영상화
AU2015229406C1 (en) 2014-03-11 2021-01-07 President And Fellows Of Harvard College High-throughput and highly multiplexed imaging with programmable nucleic acid probes
US9933431B2 (en) 2014-08-22 2018-04-03 Arizona Board Of Regents On Behalf Of Arizona State University System and method for iterative detection of biological molecules
CN107924473B (zh) 2015-08-07 2021-11-23 哈佛学院院长及董事 蛋白质-蛋白质相互作用的超分辨成像
DE102016103562A1 (de) 2015-09-17 2017-03-23 Topos Nomos Ltd. Pharmazeutische Wirkstoffe zur Verwendung in der Behandlung von Amyotropher Lateralsklerose (ALS) und Diagnoseverfahren
DE102016106510A1 (de) 2016-04-08 2017-10-12 ToposNomos Ltd. Verfahren und Vorrichtung zum extrakorporalen Entfernen von pathogenen und/oder überzähligen Bestandteilen aus einer Zellprobe eines Patienten
CA3043639A1 (en) 2016-12-09 2018-06-14 Ultivue, Inc. Improved methods for multiplex imaging using labeled nucleic acid imaging agents
US10540535B2 (en) 2017-03-13 2020-01-21 Carl Zeiss Microscopy Gmbh Automatically identifying regions of interest on images of biological cells
EP3489684B1 (de) * 2017-11-27 2024-06-26 Miltenyi Biotec B.V. & Co. KG Verfahren zum fotobleichen von angefärbten zellen
EP3916393B1 (de) * 2020-05-27 2023-01-25 Miltenyi Biotec B.V. & Co. KG Verfahren zum nachweis von zellen durch wiederholtes färben und entfärben
US20240199857A1 (en) * 2022-12-16 2024-06-20 The Chinese University Of Hong Kong Chaotropes-assisted deep immunostaining

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4299796A (en) * 1977-04-22 1981-11-10 Vitatron Scientific B.V. Apparatus for performing tests and measurements on liquid samples
DE2903625A1 (de) * 1978-02-03 1979-08-09 Rush Presbyterian St Luke Vorrichtung zur automatischen blutanalyse
US4265855A (en) * 1978-11-03 1981-05-05 Electro-Nucleonics, Inc. System for performing immunochemical and other analyses involving phase separation
DE2903855A1 (de) * 1979-02-01 1980-08-14 Bloss Werner H Prof Dr Ing Verfahren zum automatischen markieren von zellen und bestimmung der merkmale von zellen aus zytologischen abstrichpraeparaten
DE3346532A1 (de) * 1982-12-22 1984-07-12 Olympus Optical Co., Ltd., Tokio/Tokyo Verfahren zum steuern eines analysiergeraets fuer chemische analysen
US4772453A (en) * 1985-03-01 1988-09-20 Lisenbee Wayne F Luminiscence measurement arrangement
US4816418A (en) * 1985-07-22 1989-03-28 Sequoia-Turner Corporation Method and apparatus for performing automated, multi-sequential immunoassays
JPH0652263B2 (ja) * 1985-12-10 1994-07-06 株式会社日立製作所 細胞分析装置
CH669851A5 (de) * 1986-03-06 1989-04-14 Tecan Ag
US5104621A (en) * 1986-03-26 1992-04-14 Beckman Instruments, Inc. Automated multi-purpose analytical chemistry processing center and laboratory work station
GR871619B (en) * 1986-10-31 1988-03-03 Genetic Systems Corp Automated patient sample analysis instrument
US5306510A (en) * 1988-01-14 1994-04-26 Cyberlab, Inc. Automated pipetting system
US5720928A (en) * 1988-09-15 1998-02-24 New York University Image processing and analysis of individual nucleic acid molecules
DE3836716A1 (de) * 1988-10-28 1990-05-03 Zeiss Carl Fa Verfahren zur auswertung von zellbildern
JP2654682B2 (ja) * 1989-02-17 1997-09-17 富士写真フイルム株式会社 生化学分析装置、生化学分析補正方法及び補正値記録体
US5213761A (en) * 1989-04-12 1993-05-25 Olympus Optical Co., Ltd. Automatic chemical analyzer having an improved delivery mechanism
JPH049669A (ja) * 1990-04-26 1992-01-14 Hitachi Ltd 液体試料自動サンプリング装置
DE4110217A1 (de) * 1991-03-28 1992-10-01 Ullrich Juergen Heinz Verfahren zur herstellung von kristallisaten zur fruehdiagnose oder zur praevention von erkrankungen und zur herstellung von arzneimitteln
DE4211904C2 (de) * 1991-04-09 1994-03-17 Werner Maier Automatisches Verfahren zum Erstellen einer Liste unterschiedlicher Arten für eine flüssige Probe
US5312757A (en) * 1991-05-02 1994-05-17 Olympus Optical Co., Ltd. Sample distributing method
JP3157601B2 (ja) * 1992-04-27 2001-04-16 オリンパス光学工業株式会社 自動血液分析機
JP3129015B2 (ja) * 1993-02-16 2001-01-29 株式会社日立製作所 染色された粒子の検査方法及びその装置
US5589351A (en) * 1994-12-06 1996-12-31 Nps Pharmaceuticals, Inc. Fluorescence detection apparatus
DE19709348C2 (de) * 1996-05-29 1999-07-01 Schubert Walter Dr Md Automatisches Multi-Epitop-Ligand-Kartierungsverfahren

Also Published As

Publication number Publication date
DE19709348A1 (de) 1997-12-04
DE19709348C2 (de) 1999-07-01
US6150173A (en) 2000-11-21

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