DE50106822D1 - Farbstoffpaare für fluoreszenz-resonanz-energie-transfer (fret) messungen - Google Patents

Farbstoffpaare für fluoreszenz-resonanz-energie-transfer (fret) messungen

Info

Publication number
DE50106822D1
DE50106822D1 DE50106822T DE50106822T DE50106822D1 DE 50106822 D1 DE50106822 D1 DE 50106822D1 DE 50106822 T DE50106822 T DE 50106822T DE 50106822 T DE50106822 T DE 50106822T DE 50106822 D1 DE50106822 D1 DE 50106822D1
Authority
DE
Germany
Prior art keywords
dyes
energy transfer
resonance energy
fluorescence resonance
fret
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE50106822T
Other languages
German (de)
English (en)
Inventor
Daniel Belik
Hans-Dieter Josel
Rupert Herrmann
Bernhard Koenig
Francis Mueller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Application granted granted Critical
Publication of DE50106822D1 publication Critical patent/DE50106822D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
DE50106822T 2000-11-16 2001-11-14 Farbstoffpaare für fluoreszenz-resonanz-energie-transfer (fret) messungen Expired - Lifetime DE50106822D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00124995 2000-11-16
PCT/EP2001/013152 WO2002041001A1 (de) 2000-11-16 2001-11-14 Farbstoffpaare für fluoreszenz-resonanz-energie-transfer (fret) messungen

Publications (1)

Publication Number Publication Date
DE50106822D1 true DE50106822D1 (de) 2005-08-25

Family

ID=8170391

Family Applications (1)

Application Number Title Priority Date Filing Date
DE50106822T Expired - Lifetime DE50106822D1 (de) 2000-11-16 2001-11-14 Farbstoffpaare für fluoreszenz-resonanz-energie-transfer (fret) messungen

Country Status (9)

Country Link
US (1) US6908769B2 (enExample)
EP (1) EP1337851B1 (enExample)
JP (1) JP3905838B2 (enExample)
AT (1) ATE300050T1 (enExample)
AU (1) AU2002221848A1 (enExample)
CA (1) CA2426479C (enExample)
DE (1) DE50106822D1 (enExample)
ES (1) ES2245995T3 (enExample)
WO (1) WO2002041001A1 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE518913T1 (de) * 2000-09-06 2011-08-15 Evotec Ag Verfahren zur gezielten markierung mittels affinitätsmarkierter detektionsmarker
AU2003251986A1 (en) * 2002-07-17 2004-02-02 U.S.Genomics, Inc. Methods and compositions for analyzing polymers using chimeric tags
GB2421412B (en) * 2003-02-26 2007-08-29 Tomtom Bv Navigation device with touch screen
CN100447145C (zh) * 2003-08-18 2008-12-31 诺瓦提斯公司 适宜作为近红外显像剂的3h－吩嗪衍生物、其制备和用途
ATE403870T1 (de) 2003-10-01 2008-08-15 Wallac Oy Verbesserter homogenener zeitaufgelöster energietransfertest
US8105849B2 (en) * 2004-02-27 2012-01-31 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements
EP1725587A2 (en) * 2004-03-19 2006-11-29 U.S. Genomics, Inc. Compositions and methods for detection of single molecules
US8883486B2 (en) 2004-05-04 2014-11-11 Universite De Montreal Arrestin biosensor
CN100473988C (zh) * 2004-07-08 2009-04-01 厦门大学 具有荧光共振能量转移特点的蛋白组合及其用途
WO2006080396A1 (ja) * 2005-01-28 2006-08-03 Shionogi & Co., Ltd. 組換え蛋白質の定量法
WO2006125855A1 (en) * 2005-05-24 2006-11-30 Hidex Oy Correction method and measurement device for anti-stokes photoluminescence measurement
WO2007016975A1 (en) 2005-07-29 2007-02-15 F. Hoffmann-La Roche Ag Kinase and phosphatase assays based on fret
FR2890174B1 (fr) * 2005-08-30 2009-04-24 Cis Bio Internat Sa Procede pour la mise en evidence d'un processus biologique par mesure d'un fret
US20100035247A1 (en) * 2005-11-04 2010-02-11 U.S. Genomics, Inc. Heterogeneous Assay of Analytes in Solution Using Polymers
WO2007135368A2 (en) 2006-05-18 2007-11-29 Solexa Limited Dye compounds and the use of their labelled conjugates
US20110098309A1 (en) * 2007-07-12 2011-04-28 Acumen Pharmaceuticals, Inc. Methods of inhibiting the formation of amyloid-beta diffusable ligands using acylhydrazide compounds
US8962677B2 (en) * 2007-07-12 2015-02-24 Acumen Pharmaceuticals, Inc. Methods of restoring cognitive ability using non-peptidic compounds
US9006283B2 (en) 2007-07-12 2015-04-14 Acumen Pharmaceuticals, Inc. Methods of modifying amyloid β oligomers using non-peptidic compounds
US20100294665A1 (en) * 2007-07-12 2010-11-25 Richard Allen Method and system for transferring and/or concentrating a sample
CA2707309A1 (en) 2007-12-18 2009-06-25 Acumen Pharmaceuticals, Inc. Novel addl receptor polypeptides, polynucleotides and host cells for recombinant production
WO2010117420A2 (en) * 2009-03-30 2010-10-14 Pacific Biosciences Of California, Inc. Fret-labeled compounds and uses therefor
EP2425249B1 (fr) * 2009-04-30 2014-07-16 Cisbio Bioassays Procede de detection de composes modulateurs de dimeres de proteines membranaires a domaine vft
CA2810725A1 (en) 2010-09-15 2012-03-22 Constance Neely Wilson Methods of use and kit for measurement of lipopolysaccharide with a time resolved fluorescence based assay
US9435805B2 (en) 2010-09-23 2016-09-06 Woundchek Laboratories (Us), Inc. Ultrasensitive detection of beta hemolytic Streptococcus
US8569254B2 (en) 2010-12-10 2013-10-29 National Yang Ming University Methods for modulating the expression and aggregation of CAG-expanded gene product in cells and methods for identifying agents useful for doing the same
CN109752552A (zh) * 2017-11-05 2019-05-14 江苏维赛科技生物发展有限公司 检测联苯的时间分辨荧光免疫试剂盒及其检测方法
WO2019212946A1 (en) 2018-04-30 2019-11-07 Ribon Therapeutics Inc. Screening methods for parp modulators
KR102267067B1 (ko) * 2020-01-16 2021-06-21 경희대학교 산학협력단 다이에틸싸이아노포스포네이트 검출용 형광 프로브 화합물 및 이의 용도

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3262442D1 (en) 1981-10-06 1985-03-28 Univ Leland Stanford Junior Fluorescent conjugates for analysis of molecules and cells
US4822733A (en) * 1985-05-28 1989-04-18 Amoco Corporation Lifetime-resolved assay procedures
DE4137934A1 (de) 1991-11-18 1993-05-19 Boehringer Mannheim Gmbh Neue pentacyklische verbindungen und ihre verwendung als absorptions- oder fluoreszenzfarbstoffe
US5246867A (en) * 1992-01-17 1993-09-21 University Of Maryland At Baltimore Determination and quantification of saccharides by luminescence lifetimes and energy transfer
US5622821A (en) * 1994-06-29 1997-04-22 The Regents Of The University Of California Luminescent lanthanide chelates and methods of use
PT912766E (pt) * 1996-06-04 2009-07-16 Univ Utah Res Found Monitorização da hibridização durante a pcr
EP0968411A1 (en) 1997-03-25 2000-01-05 Photonic Research Systems Limited Luminescence assays
AU3487499A (en) 1998-04-08 1999-10-25 Regents Of The University Of California, The Methods and reagents for targeting organic compounds to selected cellular locations
GB9811483D0 (en) * 1998-05-29 1998-07-29 Photonic Research Systems Limi Luminescence assay using cyclical excitation wavelength sequence
US5998146A (en) * 1998-07-17 1999-12-07 Wallac Oy Homogeneous luminescence assay method based on energy transfer
AU3488700A (en) 1999-02-12 2000-08-29 Ljl Biosystems, Inc. Luminescent metal-ligand complexes

Also Published As

Publication number Publication date
JP2004514139A (ja) 2004-05-13
US20040076979A1 (en) 2004-04-22
AU2002221848A1 (en) 2002-05-27
CA2426479A1 (en) 2003-04-22
ES2245995T3 (es) 2006-02-01
EP1337851A1 (de) 2003-08-27
ATE300050T1 (de) 2005-08-15
WO2002041001A1 (de) 2002-05-23
EP1337851B1 (de) 2005-07-20
US6908769B2 (en) 2005-06-21
JP3905838B2 (ja) 2007-04-18
CA2426479C (en) 2007-08-07

Similar Documents

Publication Publication Date Title
DE50106822D1 (de) Farbstoffpaare für fluoreszenz-resonanz-energie-transfer (fret) messungen
Diamandis et al. Europium chelate labels in time-resolved fluorescence immunoassays and DNA hybridization assays
Herman et al. Frequency‐domain fluorescence microscopy with the LED as a light source
NO986043L (no) Fluorescent energioverf°ringsligand interaksjonsassay pÕ en lipid film
DK0537270T3 (da) Påvisning af analytter ved overføring af fluorescensenergi
ATE319078T1 (de) Dataträger für testvorrichtung
ATE372289T1 (de) Messstreifenspenderanordnung
ATE308038T1 (de) Fluorimeter für immunoassay
EP0788601A4 (en) LONG-LASTING ANISOTROPY (POLARIZATION) PROBE FOR CLINICAL CHEMISTRY, IMMUNOASSAYS, AFFINITY ASSAYS AND BIOMEDICAL RESEARCH
CN105806830B (zh) 一种稳定的hrp酶促化学发光底物液、其制备方法及应用
DE60223402D1 (de) Lesevorrichtung, verfahren und system für lateralfluss-assayteststreifen
ATE412050T1 (de) Fluoreszenzprotein-sensoren zur erkennung von analyten
Qin et al. A sensitive gold nanoparticles sensing platform based on resonance energy transfer for chemiluminescence light on detection of biomolecules
EP1271133A4 (en) MEASURING METHOD IN WHICH LONG-TERM FLUORESCENCE OF THE TYPE OF EXCITATION IS USED
WO2008123180A1 (ja) 標的物質の検出方法、並びに、これに用いるタグ、ｄｎａ、ベクター、プローブ及び検出キット
ATE412772T1 (de) Fluoreszenzspektroskopie in absorbierenden medien
Zhu et al. Label-free aptamer-based sensors for L-argininamide by using nucleic acid minor groove binding dyes
DE60113811D1 (de) NACHWEIS DER BINDUNG VON Ladungsträgern mittels PH- ODER POTENTiaL-SENSITIVEr SONDEN
Kokko et al. Terbium (III) chelate as an efficient donor for multiple-wavelength fluorescent acceptors
ATE440274T1 (de) Verfahren zur relativen messung der fluoreszenzquantumseffizienz von farbstoffen in lísungen
GB2433993A (en) A novel probe and its use in bioaffinity assays
ES2081861T3 (es) Inmunoensayo de polarizacion de fluorescencia para la metadona.
SE9103427D0 (sv) Foerfarande vid kvantifiering av en substans med hjaelp av fluorescens
RU2034297C1 (ru) Способ определения нарушений порфиринового обмена
Farjami et al. Innovation of new Florescent-epitope technique for immune assay methods

Legal Events

Date Code Title Description
8364 No opposition during term of opposition