DE50002721D1 - Vorrichtung zum konzentrieren und/oder reinigen von makromolekülen in einer lösung und verfahren zum herstellen einer derartigen vorrichtung - Google Patents

Vorrichtung zum konzentrieren und/oder reinigen von makromolekülen in einer lösung und verfahren zum herstellen einer derartigen vorrichtung

Info

Publication number
DE50002721D1
DE50002721D1 DE50002721T DE50002721T DE50002721D1 DE 50002721 D1 DE50002721 D1 DE 50002721D1 DE 50002721 T DE50002721 T DE 50002721T DE 50002721 T DE50002721 T DE 50002721T DE 50002721 D1 DE50002721 D1 DE 50002721D1
Authority
DE
Germany
Prior art keywords
membrane
chamber
filtrate
macromolecules
concentrating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE50002721T
Other languages
German (de)
English (en)
Inventor
Vincenzo Vassarotti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sartorius Stedim Biotech GmbH
Original Assignee
Vivascience AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vivascience AG filed Critical Vivascience AG
Application granted granted Critical
Publication of DE50002721D1 publication Critical patent/DE50002721D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/08—Flat membrane modules
    • B01D63/087—Single membrane modules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/18—Apparatus therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/08—Flat membrane modules
    • B01D63/081—Manufacturing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/16—Rotary, reciprocated or vibrated modules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021—Test tubes specially adapted for centrifugation purposes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/34—Purifying; Cleaning
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4005—Concentrating samples by transferring a selected component through a membrane
    • G01N2001/4016—Concentrating samples by transferring a selected component through a membrane being a selective membrane, e.g. dialysis or osmosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Water Supply & Treatment (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Manufacturing & Machinery (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Clinical Laboratory Science (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Centrifugal Separators (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Sampling And Sample Adjustment (AREA)
  • External Artificial Organs (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE50002721T 1999-02-15 2000-02-08 Vorrichtung zum konzentrieren und/oder reinigen von makromolekülen in einer lösung und verfahren zum herstellen einer derartigen vorrichtung Expired - Lifetime DE50002721D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9900530A SE9900530D0 (sv) 1999-02-15 1999-02-15 A device for concentrating and/or purifying macromolecules in a solution and a method for manufacturing such a device
PCT/EP2000/000976 WO2000048716A2 (de) 1999-02-15 2000-02-08 Vorrichtung zum konzentrieren und/oder reinigen von makromolekülen in einer lösung und verfahren zum herstellen einer derartigen vorrichtung

Publications (1)

Publication Number Publication Date
DE50002721D1 true DE50002721D1 (de) 2003-08-07

Family

ID=20414497

Family Applications (3)

Application Number Title Priority Date Filing Date
DE50002721T Expired - Lifetime DE50002721D1 (de) 1999-02-15 2000-02-08 Vorrichtung zum konzentrieren und/oder reinigen von makromolekülen in einer lösung und verfahren zum herstellen einer derartigen vorrichtung
DE10005427A Withdrawn DE10005427A1 (de) 1999-02-15 2000-02-08 Vorrichtung zur gleichzeitigen Filtration einer Vielzahl von Flüssigkeitsproben
DE20002188U Expired - Lifetime DE20002188U1 (de) 1999-02-15 2000-02-08 Vorrichtung zum Konzentrieren und/oder Reinigen von Makromolekülen in einer Lösung

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE10005427A Withdrawn DE10005427A1 (de) 1999-02-15 2000-02-08 Vorrichtung zur gleichzeitigen Filtration einer Vielzahl von Flüssigkeitsproben
DE20002188U Expired - Lifetime DE20002188U1 (de) 1999-02-15 2000-02-08 Vorrichtung zum Konzentrieren und/oder Reinigen von Makromolekülen in einer Lösung

Country Status (7)

Country Link
US (1) US6837995B1 (https=)
EP (1) EP1144095B1 (https=)
JP (1) JP4394838B2 (https=)
AT (1) ATE244053T1 (https=)
DE (3) DE50002721D1 (https=)
SE (1) SE9900530D0 (https=)
WO (1) WO2000048716A2 (https=)

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DE10035750A1 (de) * 2000-07-22 2002-02-07 Forschungszentrum Juelich Gmbh Vorrichtung mit einer Vielzahl von Probenkammern zur Behandlung von Zellen und zur Analyse mittels lichterzeugender Verfahren sowie Filterverbund
DE10114537A1 (de) * 2001-03-21 2002-10-24 Elipsa Gmbh Array von Filtrationsmembranen mit systematisch variierenden Trenneigenschaften, Verfahren zur Herstellung und Verwendung
DE10160429B4 (de) * 2001-12-08 2008-05-08 Sartorius Stedim Biotech Gmbh Filter mit einem elektronischen Speicherelement
DE102005051645B4 (de) * 2005-10-26 2018-10-18 Rapid Sampling Technologies Ag Einrichtung zur Fraktionierung von mit Partikeln beladenen Flüssigkeiten
US8357296B2 (en) 2007-09-24 2013-01-22 Emd Millipore Corporation Centrifugal filter
DE202011002150U1 (de) * 2011-01-31 2011-07-20 Sartorius Stedim Biotech Gmbh Filtrationsbehälter
DE202011002149U1 (de) 2011-01-31 2011-10-26 Sartorius Stedim Biotech Gmbh Filtrationsbehälter
US9304070B2 (en) 2011-07-13 2016-04-05 Emd Millipore Corporation All-in-one sample preparation device and method
EP2727643A1 (en) 2012-10-31 2014-05-07 Takeda GmbH Cross-flow ultrafiltration device and method for concentration of pharmaceutical compositions
US11293021B1 (en) 2016-06-23 2022-04-05 Inscripta, Inc. Automated cell processing methods, modules, instruments, and systems
US10011849B1 (en) 2017-06-23 2018-07-03 Inscripta, Inc. Nucleic acid-guided nucleases
US9982279B1 (en) 2017-06-23 2018-05-29 Inscripta, Inc. Nucleic acid-guided nucleases
MX2019015505A (es) 2017-06-30 2020-07-28 Inscripta Inc Metodos, modulos, instrumentos y sistemas de procesamiento de celulas automatizados.
US10738327B2 (en) 2017-08-28 2020-08-11 Inscripta, Inc. Electroporation cuvettes for automation
EP3687621A4 (en) 2017-09-30 2021-08-11 Inscripta, Inc. Flow through electroporation instrumentation
WO2019190874A1 (en) 2018-03-29 2019-10-03 Inscripta, Inc. Automated control of cell growth rates for induction and transformation
US10376889B1 (en) 2018-04-13 2019-08-13 Inscripta, Inc. Automated cell processing instruments comprising reagent cartridges
US10858761B2 (en) 2018-04-24 2020-12-08 Inscripta, Inc. Nucleic acid-guided editing of exogenous polynucleotides in heterologous cells
US10526598B2 (en) 2018-04-24 2020-01-07 Inscripta, Inc. Methods for identifying T-cell receptor antigens
US10508273B2 (en) 2018-04-24 2019-12-17 Inscripta, Inc. Methods for identifying selective binding pairs
AU2019292919A1 (en) 2018-06-30 2021-03-11 Inscripta, Inc. Instruments, modules, and methods for improved detection of edited sequences in live cells
US10752874B2 (en) 2018-08-14 2020-08-25 Inscripta, Inc. Instruments, modules, and methods for improved detection of edited sequences in live cells
US11142740B2 (en) 2018-08-14 2021-10-12 Inscripta, Inc. Detection of nuclease edited sequences in automated modules and instruments
US10532324B1 (en) 2018-08-14 2020-01-14 Inscripta, Inc. Instruments, modules, and methods for improved detection of edited sequences in live cells
AU2019368215B2 (en) 2018-10-22 2023-05-18 Inscripta, Inc. Engineered enzymes
US11214781B2 (en) 2018-10-22 2022-01-04 Inscripta, Inc. Engineered enzyme
US10864483B2 (en) * 2018-11-16 2020-12-15 Integrated Protein Technologies, Snc. Molecular weight filtration system and apparatus
EP3702017A1 (en) 2019-02-26 2020-09-02 Sartorius Stedim Lab Ltd. Crossflow filter device
CN113631713A (zh) 2019-03-25 2021-11-09 因思科瑞普特公司 酵母中的同时多重基因组编辑
US11001831B2 (en) 2019-03-25 2021-05-11 Inscripta, Inc. Simultaneous multiplex genome editing in yeast
AU2020288623A1 (en) 2019-06-06 2022-01-06 Inscripta, Inc. Curing for recursive nucleic acid-guided cell editing
US10907125B2 (en) 2019-06-20 2021-02-02 Inscripta, Inc. Flow through electroporation modules and instrumentation
US11203762B2 (en) 2019-11-19 2021-12-21 Inscripta, Inc. Methods for increasing observed editing in bacteria
KR102776469B1 (ko) 2019-12-10 2025-03-05 인스크립타 인코포레이티드 신규 mad 뉴클레아제
US10704033B1 (en) 2019-12-13 2020-07-07 Inscripta, Inc. Nucleic acid-guided nucleases
EP4069851A4 (en) 2019-12-18 2023-11-22 Inscripta, Inc. Cascade/dcas3 complementation assays for in vivo detection of nucleic acid-guided nuclease edited cells
AU2021213705A1 (en) 2020-01-27 2022-06-16 Inscripta, Inc. Electroporation modules and instrumentation
US20210332388A1 (en) 2020-04-24 2021-10-28 Inscripta, Inc. Compositions, methods, modules and instruments for automated nucleic acid-guided nuclease editing in mammalian cells
GB2598397B (en) 2020-09-01 2024-08-14 Uni Glory Holdings Ltd A chroma key and presentation system, method, and kit
WO2022060749A1 (en) 2020-09-15 2022-03-24 Inscripta, Inc. Crispr editing to embed nucleic acid landing pads into genomes of live cells
US11512297B2 (en) 2020-11-09 2022-11-29 Inscripta, Inc. Affinity tag for recombination protein recruitment
AU2021415461A1 (en) 2021-01-04 2023-08-17 Inscripta, Inc. Mad nucleases
US20240376451A1 (en) 2021-01-07 2024-11-14 Inscripta, Inc. Mad nucleases
US20240075431A1 (en) 2021-01-22 2024-03-07 Paul Charles Reardon Filter
EP4032603A1 (en) 2021-01-22 2022-07-27 Paul Charles Reardon Filter
US11884924B2 (en) 2021-02-16 2024-01-30 Inscripta, Inc. Dual strand nucleic acid-guided nickase editing

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US4948564A (en) * 1986-10-28 1990-08-14 Costar Corporation Multi-well filter strip and composite assemblies
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SE9301759D0 (sv) * 1993-05-21 1993-05-21 Vincenzo Vassarotti Centrifugal method for concentrating macromolecules from a solution and device for carrying out said method

Also Published As

Publication number Publication date
EP1144095A3 (de) 2002-03-06
WO2000048716A3 (de) 2001-11-01
DE20002188U1 (de) 2000-05-11
DE10005427A1 (de) 2000-08-17
JP2002537087A (ja) 2002-11-05
SE9900530D0 (sv) 1999-02-15
EP1144095B1 (de) 2003-07-02
US6837995B1 (en) 2005-01-04
JP4394838B2 (ja) 2010-01-06
ATE244053T1 (de) 2003-07-15
WO2000048716A2 (de) 2000-08-24
EP1144095A2 (de) 2001-10-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SARTORIUS STEDIM BIOTECH GMBH, 37079 GOETTINGE, DE