DE412557T1 - Wachstumsfaktor aus parenchymalen lebenszellen, dafuer kodierendes gen, verfahren zur herstellung dieses faktors und transformanten. - Google Patents

Wachstumsfaktor aus parenchymalen lebenszellen, dafuer kodierendes gen, verfahren zur herstellung dieses faktors und transformanten.

Info

Publication number
DE412557T1
DE412557T1 DE199090115397T DE90115397T DE412557T1 DE 412557 T1 DE412557 T1 DE 412557T1 DE 199090115397 T DE199090115397 T DE 199090115397T DE 90115397 T DE90115397 T DE 90115397T DE 412557 T1 DE412557 T1 DE 412557T1
Authority
DE
Germany
Prior art keywords
factor
growth factor
parenchymal
transformers
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE199090115397T
Other languages
English (en)
Inventor
910 Merodii-Haimu-Dainichi Naomi Moriguchi-Shi Osaka-Fu Jp Kitamura
Keiji Hirakata-Shi Osaka-Fu Jp Miyazawa
Yasushi Daikuhara
Hirohito Kagoshima-Shi Kagoshima-Ken Jp Tsubouchi
Daiji Yokohama-Shi Kanagawa-Ken Jp Naka
Kazuhiro Machida-Shi Tokyo Jp Takahashi
Rie Bunkyo-Ku Tokyo Jp Matsui
Yoshiko Yoshiyama
Takehisa Yokohama-Shi Kanagawa-Ken Jp Ishii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kasei Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27305852&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE412557(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from JP1209449A external-priority patent/JP2577091B2/ja
Priority claimed from JP2088592A external-priority patent/JP3036782B2/ja
Priority claimed from JP2200898A external-priority patent/JP2963163B2/ja
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Publication of DE412557T1 publication Critical patent/DE412557T1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Soft Magnetic Materials (AREA)
DE199090115397T 1989-08-11 1990-08-10 Wachstumsfaktor aus parenchymalen lebenszellen, dafuer kodierendes gen, verfahren zur herstellung dieses faktors und transformanten. Pending DE412557T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP1209449A JP2577091B2 (ja) 1989-08-11 1989-08-11 肝実質細胞増殖因子及びそれをコードする遺伝子
JP2088592A JP3036782B2 (ja) 1990-04-03 1990-04-03 ヒト肝実質細胞増殖因子の生産方法および該因子を産生する形質転換体
JP2200898A JP2963163B2 (ja) 1990-07-27 1990-07-27 ヒト肝実質細胞増殖因子

Publications (1)

Publication Number Publication Date
DE412557T1 true DE412557T1 (de) 1991-07-04

Family

ID=27305852

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69030539T Expired - Lifetime DE69030539T2 (de) 1989-08-11 1990-08-10 Wachstumsfaktor aus parenchymalen Lebenszellen, dafür kodierendes Gen, Verfahren zur Herstellung dieses Faktors und Transformanten
DE199090115397T Pending DE412557T1 (de) 1989-08-11 1990-08-10 Wachstumsfaktor aus parenchymalen lebenszellen, dafuer kodierendes gen, verfahren zur herstellung dieses faktors und transformanten.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69030539T Expired - Lifetime DE69030539T2 (de) 1989-08-11 1990-08-10 Wachstumsfaktor aus parenchymalen Lebenszellen, dafür kodierendes Gen, Verfahren zur Herstellung dieses Faktors und Transformanten

Country Status (7)

Country Link
US (1) US5500354A (de)
EP (1) EP0412557B1 (de)
KR (1) KR960006122B1 (de)
AT (1) ATE152124T1 (de)
CA (1) CA2022752C (de)
DE (2) DE69030539T2 (de)
HU (1) HUT58798A (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9003621D0 (en) * 1990-02-16 1990-04-11 Imp Cancer Res Tech Protein factor
JP2784455B2 (ja) * 1990-05-09 1998-08-06 敏一 中村 肝硬変治療剤
EP0461560B1 (de) * 1990-06-11 1998-11-18 Toshikazu Nakamura Rekombinanter menschlicher Hepatozytwachstumsfaktor und Verfahren zu seiner Herstellung
JP2750372B2 (ja) * 1990-06-19 1998-05-13 敏一 中村 賢疾患治療剤
DK0539590T3 (da) * 1990-07-13 1999-10-11 Snow Brand Milk Products Co Ltd Plasmid indeholdende DNA, som koder for aminosyresekvensen af TCF-II, en transformeret celle og fremstilling af et fysiolog
JP3200609B2 (ja) * 1990-12-28 2001-08-20 敏一 中村 上皮細胞増殖促進剤
TW318142B (de) * 1991-06-03 1997-10-21 Mitsubishi Chemicals Co Ltd
EP0550296A3 (en) * 1991-11-28 1993-12-29 Terumo Corp Vascular endothelial cells growth factor
US5328837A (en) * 1992-05-18 1994-07-12 Genentech, Inc. Hepatocyte growth factor protease domain variants
EP0642580B1 (de) * 1992-05-18 2002-08-21 Genentech, Inc. Hepatozytwachstumfaktor Variante
US5316921A (en) * 1992-05-18 1994-05-31 Genentech, Inc. Single-chain hepatocyte growth factor variants
CA2102463A1 (en) * 1992-11-05 1994-05-06 Mitsubishi Chemical Corporation Protein and gene encoding said protein
GB9301453D0 (en) * 1993-01-26 1993-03-17 Clonit Spa Nucleotide proves
US5807711A (en) * 1993-03-23 1998-09-15 Taisho Pharmaceutical Co., Ltd. Parenchymal hepatocyte growth factors
CZ298364B6 (cs) * 1998-02-05 2007-09-05 Smithkline Beecham Biologicals S. A. Deriváty antigenu asociovaných s nádory z MAGE rodiny a sekvence nukleových kyselin kodující tyto deriváty, jejich použití pro prípravu fúzních proteinu a prostredku pro vakcinaci
US7129064B2 (en) 2000-06-22 2006-10-31 Nippon Zenyaku Kogyo Ltd. Canine hepatocyte growth factor
KR20020097319A (ko) * 2001-06-20 2002-12-31 윤재승 사람 간세포 성장인자 코딩 벡터, 형질전환 균주 및이로부터 발현된 재조합 단백질
KR100562824B1 (ko) 2002-03-20 2006-03-23 주식회사 바이로메드 유전자 발현효율이 높으며 간세포 성장인자의 두 가지이형체를 동시에 발현하는 하이브리드 간세포 성장인자유전자
US20090202606A1 (en) * 2008-01-25 2009-08-13 Viromed Co., Ltd. Treatment and Prevention of Cardiac Conditions Using Two or More Isoforms of Hepatocyte Growth Factor
AU2009234598C1 (en) * 2008-04-09 2012-08-23 Viromed Co., Ltd. Lyophilized DNA formulations for enhanced expression of plasmid DNA
US9272018B2 (en) 2011-04-18 2016-03-01 Kyoto University Acute hepatic insufficiency depressant and method for evaluating drug efficacy thereof
JP6240337B2 (ja) 2013-10-22 2017-11-29 バイロメッド カンパニー リミテッド 肝細胞増殖因子の２つ以上のアイソフォームを利用した筋萎縮性側索硬化症の予防又は治療用組成物
KR101808192B1 (ko) * 2016-08-26 2018-01-18 아미코젠주식회사 7-아미노세팔로스포란산의 고농도 생산 재조합 아크레모니움 크리소제눔 균주의 제조방법 및 이 방법으로 제조된 균주
EP3823677A4 (de) 2018-07-19 2022-06-01 Helixmith Co., Ltd. Lyophilisierte pharmazeutische zusammensetzungen für nackte dna-gentherapie

Also Published As

Publication number Publication date
EP0412557B1 (de) 1997-04-23
HUT58798A (en) 1992-03-30
ATE152124T1 (de) 1997-05-15
EP0412557A1 (de) 1991-02-13
KR960006122B1 (ko) 1996-05-09
US5500354A (en) 1996-03-19
KR910004803A (ko) 1991-03-29
CA2022752A1 (en) 1991-02-12
DE69030539T2 (de) 1997-09-11
DE69030539D1 (de) 1997-05-28
HU904957D0 (en) 1991-01-28
CA2022752C (en) 1998-07-07

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