DE4101895C1 - - Google Patents

Info

Publication number
DE4101895C1
DE4101895C1 DE4101895A DE4101895A DE4101895C1 DE 4101895 C1 DE4101895 C1 DE 4101895C1 DE 4101895 A DE4101895 A DE 4101895A DE 4101895 A DE4101895 A DE 4101895A DE 4101895 C1 DE4101895 C1 DE 4101895C1
Authority
DE
Germany
Prior art keywords
amino acid
general formula
group
oligopeptide
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE4101895A
Other languages
German (de)
English (en)
Inventor
Andreas 5300 Bonn De Fischer
Alexander Rehovot Is Schwarz
Christian Prof. Dipl.-Chem. 5170 Juelich De Wandrey
Guenter Dr. 6454 Bruchkoebel De Knaup
Andreas Dr. 6000 Frankfurt De Bommarius
Karl-Heinz Dr. 6364 Freigericht De Drauz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evonik Operations GmbH
Original Assignee
Forschungszentrum Juelich GmbH
Degussa GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forschungszentrum Juelich GmbH, Degussa GmbH filed Critical Forschungszentrum Juelich GmbH
Priority to DE4101895A priority Critical patent/DE4101895C1/de
Application granted granted Critical
Publication of DE4101895C1 publication Critical patent/DE4101895C1/de
Priority to JP00941192A priority patent/JP3447066B2/ja
Priority to EP92101000A priority patent/EP0496373B1/de
Priority to AT92101000T priority patent/ATE165868T1/de
Priority to DE59209313T priority patent/DE59209313D1/de
Priority to US07/823,956 priority patent/US5304470A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
DE4101895A 1991-01-23 1991-01-23 Expired - Lifetime DE4101895C1 (US07723303-20100525-C00002.png)

Priority Applications (6)

Application Number Priority Date Filing Date Title
DE4101895A DE4101895C1 (US07723303-20100525-C00002.png) 1991-01-23 1991-01-23
JP00941192A JP3447066B2 (ja) 1991-01-23 1992-01-22 水性溶液の形で保護された及び保護されていないジ− 及びオリゴペプチドの酵素による製造方法
EP92101000A EP0496373B1 (de) 1991-01-23 1992-01-22 Verfahren zur enzymatischen Herstellung geschützter und ungeschützter Di- und Oligopeptide in wässrigen Lösungen
AT92101000T ATE165868T1 (de) 1991-01-23 1992-01-22 Verfahren zur enzymatischen herstellung geschützter und ungeschützter di- und oligopeptide in wässrigen lösungen
DE59209313T DE59209313D1 (de) 1991-01-23 1992-01-22 Verfahren zur enzymatischen Herstellung geschützter und ungeschützter Di- und Oligopeptide in wässrigen Lösungen
US07/823,956 US5304470A (en) 1991-01-23 1992-01-23 Process for the enzymatic preparation of protected and unprotected di- and oligopeptides in aqueous solutions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4101895A DE4101895C1 (US07723303-20100525-C00002.png) 1991-01-23 1991-01-23

Publications (1)

Publication Number Publication Date
DE4101895C1 true DE4101895C1 (US07723303-20100525-C00002.png) 1991-12-05

Family

ID=6423542

Family Applications (2)

Application Number Title Priority Date Filing Date
DE4101895A Expired - Lifetime DE4101895C1 (US07723303-20100525-C00002.png) 1991-01-23 1991-01-23
DE59209313T Expired - Fee Related DE59209313D1 (de) 1991-01-23 1992-01-22 Verfahren zur enzymatischen Herstellung geschützter und ungeschützter Di- und Oligopeptide in wässrigen Lösungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE59209313T Expired - Fee Related DE59209313D1 (de) 1991-01-23 1992-01-22 Verfahren zur enzymatischen Herstellung geschützter und ungeschützter Di- und Oligopeptide in wässrigen Lösungen

Country Status (5)

Country Link
US (1) US5304470A (US07723303-20100525-C00002.png)
EP (1) EP0496373B1 (US07723303-20100525-C00002.png)
JP (1) JP3447066B2 (US07723303-20100525-C00002.png)
AT (1) ATE165868T1 (US07723303-20100525-C00002.png)
DE (2) DE4101895C1 (US07723303-20100525-C00002.png)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996001906A1 (de) * 1994-07-08 1996-01-25 Degussa Aktiengesellschaft Kinetisch kontrolliertes verfahren zur enzymatischen herstellung von peptiden

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW306932B (US07723303-20100525-C00002.png) * 1993-08-27 1997-06-01 Holland Sweetener Co
EP0975353B1 (en) 1997-04-18 2005-11-09 Cephalon, Inc. Peptidyl-2-amino-1-hydroxyalkanesulfonic acid cysteine protease inhibitors
US6605590B1 (en) 1999-10-29 2003-08-12 Novus International, Inc. Oligomers and oligomeric segments of alpha-hydroxy carboxylic acids and alpha-amino acids
US6939693B2 (en) * 1999-10-29 2005-09-06 Novus International, Inc. Enantioselective oligomerization of α-hydroxy carboxylic acids and α-amino acids
US7199102B2 (en) * 2000-08-24 2007-04-03 The Regents Of The University Of California Orally administered peptides synergize statin activity
US7148197B2 (en) * 2000-08-24 2006-12-12 The Regents Of The University Of California Orally administered small peptides synergize statin activity
US7723303B2 (en) * 2000-08-24 2010-05-25 The Regents Of The University Of California Peptides and peptide mimetics to treat pathologies characterized by an inflammatory response
US20040052928A1 (en) * 2002-09-06 2004-03-18 Ehud Gazit Peptides and methods using same for diagnosing and treating amyloid-associated diseases
US7781396B2 (en) * 2002-01-31 2010-08-24 Tel Aviv University Future Technology Development L.P. Peptides directed for diagnosis and treatment of amyloid-associated disease
US7491699B2 (en) * 2002-12-09 2009-02-17 Ramot At Tel Aviv University Ltd. Peptide nanostructures and methods of generating and using the same
EP2058275A1 (en) 2003-01-07 2009-05-13 Ramot at Tel-Aviv University Ltd. Peptide nanostructures encapsulating a foreign material and method of manufacturing same
EP1638517A4 (en) * 2003-06-30 2010-01-06 Univ Tel Aviv Future Tech Dev PEPTIDES, ANTIBODIES AGAINST DISEASES ASSOCIATED WITH AMYLOID AND METHODS OF USE FOR THE DIAGNOSIS AND TREATMENT OF THESE DISEASES
CA2540407A1 (en) * 2003-09-25 2005-03-31 Tel Aviv University Future Technology Development L.P. Compositions and methods using same for treating amyloid-associated diseases
US7625707B2 (en) * 2003-10-02 2009-12-01 Ramot At Tel Aviv University Ltd. Antibacterial agents and methods of identifying and utilizing same
WO2006006172A2 (en) * 2004-07-15 2006-01-19 Ramot At Tel Aviv University Ltd. Use of anti-amyloid agents for treating and typing pathogen infections
US8568637B2 (en) * 2004-08-02 2013-10-29 Ramot At Tel-Aviv University Ltd. Method of forming a fiber made of peptide nanostructures
EP1793816B1 (en) * 2004-08-19 2012-01-04 Tel Aviv University Future Technology Development L.P. Compositions for treating amyloid associated diseases
US7786086B2 (en) * 2004-09-08 2010-08-31 Ramot At Tel-Aviv University Ltd. Peptide nanostructures containing end-capping modified peptides and methods of generating and using the same
CA2580501A1 (en) * 2004-09-16 2006-03-30 The Regents Of The University Of California G-type peptides and other agents to ameliorate atherosclerosis and other pathologies
EP1827472A4 (en) * 2004-12-06 2012-09-05 Univ California METHOD FOR IMPROVING THE STRUCTURE AND FUNCTION OF ARTERIOLS
US20080293639A1 (en) * 2005-04-29 2008-11-27 The Regents Of The University Of California Peptides and peptide mimetics to treat pathologies characterized by an inflammatory response
US10004828B2 (en) * 2005-10-11 2018-06-26 Romat at Tel-Aviv University Ltd. Self-assembled Fmoc-ff hydrogels
US7879212B2 (en) * 2005-11-03 2011-02-01 Ramot At Tel-Aviv University Ltd. Peptide nanostructure-coated electrodes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH618842A5 (en) * 1975-09-30 1980-08-29 Ciba Geigy Ag Pesticides
DE3733198A1 (de) * 1987-10-01 1989-04-13 Kernforschungsanlage Juelich Enzymatisches verfahren zur herstellung von dipeptiden

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NICHTS ERMITTELT *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996001906A1 (de) * 1994-07-08 1996-01-25 Degussa Aktiengesellschaft Kinetisch kontrolliertes verfahren zur enzymatischen herstellung von peptiden

Also Published As

Publication number Publication date
US5304470A (en) 1994-04-19
JPH0698788A (ja) 1994-04-12
EP0496373B1 (de) 1998-05-06
DE59209313D1 (de) 1998-06-10
ATE165868T1 (de) 1998-05-15
JP3447066B2 (ja) 2003-09-16
EP0496373A1 (de) 1992-07-29

Similar Documents

Publication Publication Date Title
DE4101895C1 (US07723303-20100525-C00002.png)
DE2801238C2 (de) Verfahren zur Herstellung von Salzen aus L,L-Dipeptiden und Phenylalaninestern
DE4123248C2 (de) Verfahren zur Herstellung von N-substituierten alpha-Aminosäuren und alpha-Aminosäure-Derivaten
EP0270982A2 (de) Derivate bicyclischer Aminocarbonsäuren, Verfahren und Zwischenprodukte zu deren Herstellung sowie deren Verwendung
DE2234798A1 (de) 9-nieder-alkyl-9-fluorenyloxycarbonylderivate, verfahren zu ihrer herstellung und ihre verwendung als aminogruppenschutzreagentien bei der peptidsynthese
WO1996033976A1 (de) Hydantoinderivate als zwischenprodukte für pharmazeutische wirkstoffe
EP0010587B1 (de) Adamantylalkyloxycarbonylderivate, deren Herstellung und Verwendung zur Darstellung von Peptiden
EP0394194A1 (de) Geschützte Aminosäuren und Verfahren zu ihrer Herstellung
DE2215408A1 (de) Verfahren zur Herstellung von Diketopiperazihdihydroxamaten
DE2045998C3 (de) Verfahren zum Trennen von DL-Cystein in die optischen Antipoden
EP0316725A2 (de) Verfahren zur enzymatischen Peptidsynthese mit mindestens einer nicht-proteinogenen Aminsäure sowie die neuen, bei der Synthese anfallenden Peptide
EP0812822B1 (de) Verfahren zur Herstellung von Aminoessigsäuren mit alpha-ständigem tertiären Kohlenwasserstoffrest oder deren Nitrilen
EP0129075A2 (de) Geschützte Aminosäurederivate und deren Herstellung
DE2416355A1 (de) Direkte synthese von dopaminaminosaeureamiden
DE2647188C2 (de) Verfahren zur Herstellung von Oligopeptiden
EP0370399B1 (de) Verfahren zur Herstellung von Tripeptiden
DE2245392B2 (de) Verfahren zur Herstellung von N-tert-Butyloxycarbonyl-, N-tert-Amyloxy carbonyl- oder N-4-Methoxybenzyloxycarbonylaminocarbonsäuren oder -peptiden
DE60123513T2 (de) Verfahren zur Herstellung von D-Asparaginderivaten
DE2621279A1 (de) Nonapeptidester und -amid, verfahren zu ihrer herstellung und arzneipraeparate
DE1543575C (de) Verfahren zur Herstellung von Peptiden
EP0471809B1 (de) Verfahren zur herstellung von n-geschützten (2s,3s)-3-ethylasparaginsäuredialkylestern
DD284028B5 (de) Verfahren zur Herstellung von L-Alanyl-L-prolin-Derivaten
DE3803124C2 (US07723303-20100525-C00002.png)
EP0771792A1 (de) Verfahren zur Herstellung von (4,5)-trans-Oxazolidin-derivaten
AT401931B (de) Verfahren zur herstellung von (s,s)-(n-(1- ethoxycarbonyl-3-oxo-3-phenylpropyl)-alanin)- (phenylmethyl)ester

Legal Events

Date Code Title Description
8100 Publication of patent without earlier publication of application
D1 Grant (no unexamined application published) patent law 81
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: DEGUSSA-HUELS AG, 60311 FRANKFURT, DE FORSCHUNGSZE

8327 Change in the person/name/address of the patent owner

Owner name: DEGUSSA AG, 40474 DUESSELDORF, DE FORSCHUNGSZENTRU

8327 Change in the person/name/address of the patent owner

Owner name: DEGUSSA AG, 40474 DUESSELDORF, DE

8339 Ceased/non-payment of the annual fee