DE3884645D1 - Verfahren zur Herstellung von Kollagen und daraus erhaltene Produkte. - Google Patents

Verfahren zur Herstellung von Kollagen und daraus erhaltene Produkte.

Info

Publication number
DE3884645D1
DE3884645D1 DE88102975T DE3884645T DE3884645D1 DE 3884645 D1 DE3884645 D1 DE 3884645D1 DE 88102975 T DE88102975 T DE 88102975T DE 3884645 T DE3884645 T DE 3884645T DE 3884645 D1 DE3884645 D1 DE 3884645D1
Authority
DE
Germany
Prior art keywords
collagen
production
products obtained
obtained therefrom
undenaturated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE88102975T
Other languages
English (en)
Other versions
DE3884645T2 (de
Inventor
Claudio Menicagli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Istituto Gentili SpA
Original Assignee
Istituto Gentili SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto Gentili SpA filed Critical Istituto Gentili SpA
Publication of DE3884645D1 publication Critical patent/DE3884645D1/de
Application granted granted Critical
Publication of DE3884645T2 publication Critical patent/DE3884645T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C08H1/06—Macromolecular products derived from proteins derived from horn, hoofs, hair, skin or leather
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2063—Proteins, e.g. gelatin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/84—Bones; tendons; teeth; cartilage
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/842—Skin; hair; nails; sebaceous glands; cerumen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
DE88102975T 1987-03-12 1988-02-29 Verfahren zur Herstellung von Kollagen und daraus erhaltene Produkte. Expired - Fee Related DE3884645T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8719659A IT1214505B (it) 1987-03-12 1987-03-12 Procedimento per la preparazione di collageno e prodotti cosi'ottenuto.

Publications (2)

Publication Number Publication Date
DE3884645D1 true DE3884645D1 (de) 1993-11-11
DE3884645T2 DE3884645T2 (de) 1994-01-27

Family

ID=11160155

Family Applications (1)

Application Number Title Priority Date Filing Date
DE88102975T Expired - Fee Related DE3884645T2 (de) 1987-03-12 1988-02-29 Verfahren zur Herstellung von Kollagen und daraus erhaltene Produkte.

Country Status (8)

Country Link
US (1) US4894441A (de)
EP (1) EP0284789B1 (de)
JP (2) JP2886164B2 (de)
AT (1) ATE95531T1 (de)
CA (1) CA1322166C (de)
DE (1) DE3884645T2 (de)
ES (1) ES2059414T3 (de)
IT (1) IT1214505B (de)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6919308B2 (en) * 1988-04-08 2005-07-19 Stryker Corporation Osteogenic devices
US5354557A (en) * 1988-04-08 1994-10-11 Stryker Corporation Osteogenic devices
US5266683A (en) * 1988-04-08 1993-11-30 Stryker Corporation Osteogenic proteins
US4975526A (en) * 1989-02-23 1990-12-04 Creative Biomolecules, Inc. Bone collagen matrix for zenogenic implants
US6586388B2 (en) 1988-04-08 2003-07-01 Stryker Corporation Method of using recombinant osteogenic protein to repair bone or cartilage defects
US20070166353A1 (en) * 1988-04-08 2007-07-19 Stryker Corporation Osteogenic proteins
IT216721Z2 (it) * 1989-06-30 1991-09-19 Euroresearch S R L Milano Tutore costituito da un tubolare di collageno eterologo, atto all'impiego nelle suture di organi cavi.
US5106949A (en) * 1989-09-15 1992-04-21 Organogenesis, Inc. Collagen compositions and methods for preparation thereof
ES2118723T3 (es) * 1989-10-17 1998-10-01 Stryker Corp Dispositivos osteogenicos.
US5214138A (en) * 1989-12-20 1993-05-25 Case Western Reserve University Imidazopyridinium compound and processes for isolating, identifying, and chemically synthesizing same
EP0448770A1 (de) * 1990-03-28 1991-10-02 Katsuya Takasu Verfahren zur Gewinnung von Kollagen
US5246698A (en) * 1990-07-09 1993-09-21 Biomatrix, Inc. Biocompatible viscoelastic gel slurries, their preparation and use
US5143724A (en) * 1990-07-09 1992-09-01 Biomatrix, Inc. Biocompatible viscoelastic gel slurries, their preparation and use
US20080233170A1 (en) * 1992-02-21 2008-09-25 Stryker Corporation Osteogenic Proteins
RU2084468C1 (ru) * 1995-02-17 1997-07-20 Межотраслевой научно-технический комплекс "Микрохирургия глаза" Способ получения биосовместимого полимерного материала
US6165490A (en) * 1996-04-05 2000-12-26 Staar Surgical Ag Biological material, method of preparing such materials, uses thereof and products made therefrom
RU2089198C1 (ru) * 1995-11-30 1997-09-10 Межотраслевой научно-технический комплекс "Микрохирургия глаза" Способ получения биоматериала для использования в офтальмологии
US6927287B1 (en) * 1996-06-03 2005-08-09 United States Surgical Corporation Nucleic acid encoding extracellular matrix protein or fragment thereof
US6492508B1 (en) 1996-06-03 2002-12-10 United States Surgical Corp. A Division Of Tyco Healthcare Group Nucleic acids encoding extracellular matrix proteins
US5821089A (en) * 1996-06-03 1998-10-13 Gruskin; Elliott A. Amino acid modified polypeptides
US5874006A (en) * 1996-10-31 1999-02-23 Matrix Pharmaceutical, Inc. Aseptic collagen concentration process
US5925246A (en) * 1996-10-31 1999-07-20 Matrix Pharmaceutical, Inc. Apparatus for aseptic vortex flow concentration
US5766245A (en) * 1996-12-30 1998-06-16 Staar Surgical, Ag Intraocular lens for correcting moderate to severe hypermetropia
US5814328A (en) 1997-01-13 1998-09-29 Gunasekaran; Subramanian Preparation of collagen using papain and a reducing agent
US6315900B1 (en) * 1998-06-03 2001-11-13 Accurate Polymers Static separation method using non-porous cellulose beads
US6361551B1 (en) 1998-12-11 2002-03-26 C. R. Bard, Inc. Collagen hemostatic fibers
US6454787B1 (en) 1998-12-11 2002-09-24 C. R. Bard, Inc. Collagen hemostatic foam
AU7732600A (en) * 1999-09-28 2001-04-30 Organogenesis Inc. Bioengineered collagen fibrils
US6592794B1 (en) 1999-09-28 2003-07-15 Organogenesis Inc. Process of making bioengineered collagen fibrils
IT1317832B1 (it) * 2000-02-15 2003-07-15 Eurores S R L Procedimento per la preparazione di collagene micronizzato e sueapplicazioni terapeutiche.
AT411326B (de) * 2000-06-20 2003-12-29 Biering Wolfgang Hämostatische collagen-pellets
US6995242B2 (en) 2002-07-15 2006-02-07 The Lauridsen Group, Inc. Process for producing insoluble and soluble collagen protein products from poultry skins and use thereof
JP5162812B2 (ja) * 2004-07-08 2013-03-13 大正製薬株式会社 亜鉛含有経口投与用組成物
WO2006028415A1 (en) * 2004-09-09 2006-03-16 Agency For Science, Technology And Research Process for isolating biomaterial from tissue and an isolated biomaterial extract prepared therefrom
US20070248575A1 (en) * 2006-04-19 2007-10-25 Jerome Connor Bone graft composition
JP6145630B2 (ja) * 2012-11-28 2017-06-14 地方独立行政法人青森県産業技術センター グリシンを豊富に含むタンパク質
US9474718B2 (en) 2013-05-15 2016-10-25 Europesearch S.R.L. Collagen powder, composition and use
KR101531479B1 (ko) 2014-11-21 2015-06-26 세원셀론텍(주) 의료용 재료로 사용하기 위한 고농도 콜라겐 제조방법
JP6228176B2 (ja) 2015-10-21 2017-11-08 地方独立行政法人東京都立産業技術研究センター ゼラチンまたはその化学修飾体、それを含有する水性組成物および医療用積層体、ならびに医療用積層体の製造方法および細胞シートの単離方法
CN106620847A (zh) * 2016-11-17 2017-05-10 北京华信佳音医疗科技发展有限责任公司 一种胶原生物膜及其制备方法
GB201708853D0 (en) 2017-06-02 2017-07-19 Jellagen Pty Ltd Method
CN108659117B (zh) * 2018-04-25 2020-11-03 广州创尔生物技术股份有限公司 一种定量检测胶原蛋白三股螺旋结构含量的方法
US11273123B2 (en) 2018-07-18 2022-03-15 USpharma Ltd Chewable pharmaceutical dosage forms
CN114272361A (zh) * 2021-12-17 2022-04-05 锐腾(苏州)生物科技有限公司 一种胶原蛋白分子单体皮肤涂敷液的组成和应用方法
CN114317661B (zh) * 2022-02-15 2024-04-09 无锡贝迪生物工程股份有限公司 一种制备多重活性胶原的方法
CN114632183B (zh) * 2022-03-30 2023-02-03 温州医科大学 一种创伤蛋白海绵及其制备方法和在制备皮肤修复中减少瘢痕形成的药物中的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4488911A (en) * 1975-10-22 1984-12-18 Luck Edward E Non-antigenic collagen and articles of manufacture
CA1073360A (en) * 1975-10-22 1980-03-11 John R. Daniels Non-antigenic collagen and articles of manufacture
JPS53121942A (en) * 1977-03-28 1978-10-24 Teruo Miyata Production of hemostatic agent
US4252759A (en) * 1979-04-11 1981-02-24 Massachusetts Institute Of Technology Cross flow filtration molding method
US4242291A (en) * 1979-05-09 1980-12-30 Battelle Development Corporation Collagen reconstitution
US4412947A (en) * 1979-09-12 1983-11-01 Seton Company Collagen sponge
CH645271A5 (de) * 1979-10-08 1984-09-28 Pentapharm Ag Verfahren zur herstellung eines kollagenproduktes fuer medizinische und kosmetische zwecke.
US4557764A (en) * 1984-09-05 1985-12-10 Collagen Corporation Process for preparing malleable collagen and the product thereof
FR2586703B1 (fr) * 1985-09-02 1989-12-01 Merieux Inst Procede d'extraction de collagenes placentaires, collagenes obtenus notamment sous forme de gels ou de solutions et leurs applications

Also Published As

Publication number Publication date
IT8719659A0 (it) 1987-03-12
IT1214505B (it) 1990-01-18
CA1322166C (en) 1993-09-14
EP0284789B1 (de) 1993-10-06
ES2059414T3 (es) 1994-11-16
JP2886164B2 (ja) 1999-04-26
DE3884645T2 (de) 1994-01-27
US4894441A (en) 1990-01-16
JPH11246598A (ja) 1999-09-14
JPS646300A (en) 1989-01-10
EP0284789A1 (de) 1988-10-05
ATE95531T1 (de) 1993-10-15

Similar Documents

Publication Publication Date Title
DE3884645D1 (de) Verfahren zur Herstellung von Kollagen und daraus erhaltene Produkte.
ATE79386T1 (de) Herstellung von polymilchsaeure und copolymeren daraus.
DE69900331T2 (de) Verfahren zur Herstellung von Fischgelatine
ATE163447T1 (de) Verfahren zur herstellung von kollagenfasern
DE3881364D1 (de) Verfahren zur herstellung und zusammensetzungen von kollagen-derivaten.
ATE22695T1 (de) Verfahren zur herstellung von hellfarbigen polyestern unter verwendung von titankatalysatoren.
ATE62264T1 (de) Verfahren zur herstellung von estern.
DE3882242D1 (de) Fermentationsverfahren zur herstellung von 2-keto-l-gulonsaeuren.
ATE162551T1 (de) Verfahren zur herstellung von dihomo-gamma- linolensäure und das in dieser enthaltende lipid
DE69011880D1 (de) Verfahren zur Herstellung von L-Aminosäuren durch Fermentation.
DE3780145D1 (de) Verfahren zur herstellung hochkonzentrierter phosphorsaeure.
ATE97896T1 (de) Verfahren zur herstellung von d,l-lactid.
ATE56204T1 (de) Verfahren zur herstellung von trockener alkansulfonsaeure.
NO175594C (no) Fremgangsmåte for isolering av heparin-bindende hjerne-mitogen
DE3851588D1 (de) Verfahren zur Herstellung von Chinoloncarbonsäuren.
DE3864372D1 (de) Verfahren zur herstellung von 1-aryl-alk-1-enen.
DE3772341D1 (de) Verfahren zur herstellung von carbonsaeuren.
DE3768148D1 (de) Verfahren zur herstellung von carbonsaeuren.
AT384222B (de) Verfahren zur herstellung von 7-amino-3alkoxymethyl-3-cephem-4-carbonsaeuren
DE3785119D1 (de) Verfahren zur herstellung von aminosaeuren.
DE3877324D1 (de) Verfahren zur herstellung von acrylamidomethansulfonsaeure-polymeren.
ATE86955T1 (de) Verfahren zur herstellung von alpha-a1203sinterk¯rpern.
DE3751347D1 (de) Verfahren zur Herstellung von HNS II.
ATE207139T1 (de) Verfahren zur herstellung von butantetracarbonsäure
DE68911168D1 (de) Verfahren zur Herstellung von ungesättigten Carbonsäuren.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee