DE3876836D1 - Aminochinolinderivate gegen malaria, verfahren zur herstellung und diese enthaltende pharmazeutische zusammensetzung. - Google Patents

Aminochinolinderivate gegen malaria, verfahren zur herstellung und diese enthaltende pharmazeutische zusammensetzung.

Info

Publication number
DE3876836D1
DE3876836D1 DE8888400683T DE3876836T DE3876836D1 DE 3876836 D1 DE3876836 D1 DE 3876836D1 DE 8888400683 T DE8888400683 T DE 8888400683T DE 3876836 T DE3876836 T DE 3876836T DE 3876836 D1 DE3876836 D1 DE 3876836D1
Authority
DE
Germany
Prior art keywords
derivatives
new
pharmaceutical composition
amino acid
free amine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888400683T
Other languages
English (en)
Other versions
DE3876836T2 (de
Inventor
Jean-Bernard Falmagne
Philippe Pirson
Jacques Quivy
Andre Trouet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
La Region Wallonne
Original Assignee
La Region Wallonne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by La Region Wallonne filed Critical La Region Wallonne
Application granted granted Critical
Publication of DE3876836D1 publication Critical patent/DE3876836D1/de
Publication of DE3876836T2 publication Critical patent/DE3876836T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/40—Nitrogen atoms attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06043—Leu-amino acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Quinoline Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE8888400683T 1987-03-24 1988-03-22 Aminochinolinderivate gegen malaria, verfahren zur herstellung und diese enthaltende pharmazeutische zusammensetzung. Expired - Fee Related DE3876836T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8704079A FR2612778B1 (fr) 1987-03-24 1987-03-24 Nouveaux derives d'aminoquinoleine antimalarique, procede de preparation et composition pharmaceutique en contenant

Publications (2)

Publication Number Publication Date
DE3876836D1 true DE3876836D1 (de) 1993-02-04
DE3876836T2 DE3876836T2 (de) 1993-05-06

Family

ID=9349368

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888400683T Expired - Fee Related DE3876836T2 (de) 1987-03-24 1988-03-22 Aminochinolinderivate gegen malaria, verfahren zur herstellung und diese enthaltende pharmazeutische zusammensetzung.

Country Status (8)

Country Link
EP (1) EP0286491B1 (de)
JP (1) JPS63255265A (de)
AT (1) ATE83771T1 (de)
CA (1) CA1336528C (de)
DE (1) DE3876836T2 (de)
ES (1) ES2052752T3 (de)
FR (1) FR2612778B1 (de)
GR (1) GR3006982T3 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2644462B1 (fr) * 1988-09-23 1993-07-09 Ire Celltarg Sa Nouveaux composes actifs sur les formes tissulaires de la malaria et procede de preparation
CA2133620A1 (en) * 1993-10-28 1995-04-29 Werner Hofheinz Aminoquinoline derivatives
ES2284184T3 (es) * 1996-03-29 2007-11-01 The University Of Mississippi Medicamento que comprende (-)-8-(4-amino-1-metilbutil)amino)-5-(3,4-diclorofenoxi)-6-metoxi-4-metilquinolina para el tratamiento de infecciones parasitarias y oportunistas.
JP4727233B2 (ja) * 2003-03-27 2011-07-20 カウンシル・オブ・サイエンティフィック・アンド・インダストリアル・リサーチ 抗マラリア薬としての環置換８−アミノキノリン誘導体

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3167679D1 (en) * 1980-03-31 1985-01-24 Inst Int Pathologie Cellulaire Pharmaceutical forms, their preparation and compositions containing the same

Also Published As

Publication number Publication date
GR3006982T3 (de) 1993-06-30
EP0286491B1 (de) 1992-12-23
EP0286491A1 (de) 1988-10-12
JPS63255265A (ja) 1988-10-21
CA1336528C (fr) 1995-08-01
DE3876836T2 (de) 1993-05-06
FR2612778B1 (fr) 1991-10-18
FR2612778A1 (fr) 1988-09-30
ES2052752T3 (es) 1994-07-16
ATE83771T1 (de) 1993-01-15

Similar Documents

Publication Publication Date Title
EP2269648A3 (de) Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika
FI109900B (fi) Menetelmä farmaseuttisesti aktiivisten 3,3-difenyylipropyyliamiinien valmistamiseksi
PT89110A (pt) Processo de preparacao de derivados da quinazolina e de composicoes farmaceuticas que os contem
ATE206720T1 (de) Camphothecinderivate
ATE113272T1 (de) Verfahren zur stabilisierung einer festen pharmazeutischen zubereitungsform von cyclischen aminosäuren.
DE69627035D1 (de) Derivate von aminosäuren, sie enthaltende pharmazeutische zusammensetzungen sowie deren herstellunsgverfahren
EP0664289A3 (de) Isochinoline
FI884375A0 (fi) Menetelmä terapeuttisesti käyttökelpoisten N-(1-alkyyli-3-hydroksi-4-piperidinyyli)bentsamidien valmistamiseksi
PT96400A (pt) Processo de preparacao de composicoes farmaceuticas a base de complexos de acido quinolona-carboxilico-iao metalico-acido
ATE88344T1 (de) Zur behandlung von neurodegenerativen erkrankungen verwendbare kynurensaeurederivate.
BG99729A (en) Substituted 6-azaandrostenones
DE3876836D1 (de) Aminochinolinderivate gegen malaria, verfahren zur herstellung und diese enthaltende pharmazeutische zusammensetzung.
AU581855B2 (en) 1-(4'-alkylsulphonylphenyl)-2-amino-1, 3-propanediol n-substituted derivatives
DE68907458D1 (de) Verbindungen mit aktivitaet gegen gewebemalaria und verfahren zu ihrer herstellung.
HUT69691A (en) Method for producing amino-benzoic acid derivatives and pharmaceutical preparatives containing them
HUP0203650A2 (hu) Heterociklusos származékok, eljárás az előállítására, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk
KR890701572A (ko) 고리형 아미노산의 유도체,이들의 염, 이들을 함유하는 약제조성물 및 이들의 제조방법.
DE3586752D1 (de) Verfahren zur herstellung wundheilungsfoerdernder praeparationen und solche praeparationen.
FR2655042B1 (fr) Nouvelles benzothiazolinones substituees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
AU7586191A (en) Hydroxyproline derivative, a process for the preparation thereof and pharmaceutical compositions containing it
MX9803556A (es) Derivados de aminoacidos, medicamentos que contienen tales compuestos y metodos para producirlos.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee