ATE83771T1 - Aminochinolinderivate gegen malaria, verfahren zur herstellung und diese enthaltende pharmazeutische zusammensetzung. - Google Patents

Aminochinolinderivate gegen malaria, verfahren zur herstellung und diese enthaltende pharmazeutische zusammensetzung.

Info

Publication number
ATE83771T1
ATE83771T1 AT88400683T AT88400683T ATE83771T1 AT E83771 T1 ATE83771 T1 AT E83771T1 AT 88400683 T AT88400683 T AT 88400683T AT 88400683 T AT88400683 T AT 88400683T AT E83771 T1 ATE83771 T1 AT E83771T1
Authority
AT
Austria
Prior art keywords
derivatives
new
pharmaceutical composition
amino acid
free amine
Prior art date
Application number
AT88400683T
Other languages
English (en)
Inventor
Jean-Bernard Falmagne
Philippe Pirson
Jacques Quivy
Andre Trouet
Original Assignee
Wallone Region
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wallone Region filed Critical Wallone Region
Application granted granted Critical
Publication of ATE83771T1 publication Critical patent/ATE83771T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/40—Nitrogen atoms attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06043—Leu-amino acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Quinoline Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT88400683T 1987-03-24 1988-03-22 Aminochinolinderivate gegen malaria, verfahren zur herstellung und diese enthaltende pharmazeutische zusammensetzung. ATE83771T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8704079A FR2612778B1 (fr) 1987-03-24 1987-03-24 Nouveaux derives d'aminoquinoleine antimalarique, procede de preparation et composition pharmaceutique en contenant
EP88400683A EP0286491B1 (de) 1987-03-24 1988-03-22 Aminochinolinderivate gegen Malaria, Verfahren zur Herstellung und diese enthaltende pharmazeutische Zusammensetzung

Publications (1)

Publication Number Publication Date
ATE83771T1 true ATE83771T1 (de) 1993-01-15

Family

ID=9349368

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88400683T ATE83771T1 (de) 1987-03-24 1988-03-22 Aminochinolinderivate gegen malaria, verfahren zur herstellung und diese enthaltende pharmazeutische zusammensetzung.

Country Status (8)

Country Link
EP (1) EP0286491B1 (de)
JP (1) JPS63255265A (de)
AT (1) ATE83771T1 (de)
CA (1) CA1336528C (de)
DE (1) DE3876836T2 (de)
ES (1) ES2052752T3 (de)
FR (1) FR2612778B1 (de)
GR (1) GR3006982T3 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2644462B1 (fr) * 1988-09-23 1993-07-09 Ire Celltarg Sa Nouveaux composes actifs sur les formes tissulaires de la malaria et procede de preparation
CA2133620A1 (en) * 1993-10-28 1995-04-29 Werner Hofheinz Aminoquinoline derivatives
ES2284184T3 (es) * 1996-03-29 2007-11-01 The University Of Mississippi Medicamento que comprende (-)-8-(4-amino-1-metilbutil)amino)-5-(3,4-diclorofenoxi)-6-metoxi-4-metilquinolina para el tratamiento de infecciones parasitarias y oportunistas.
JP4727233B2 (ja) * 2003-03-27 2011-07-20 カウンシル・オブ・サイエンティフィック・アンド・インダストリアル・リサーチ 抗マラリア薬としての環置換８−アミノキノリン誘導体

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3167679D1 (en) * 1980-03-31 1985-01-24 Inst Int Pathologie Cellulaire Pharmaceutical forms, their preparation and compositions containing the same

Also Published As

Publication number Publication date
GR3006982T3 (de) 1993-06-30
EP0286491B1 (de) 1992-12-23
EP0286491A1 (de) 1988-10-12
JPS63255265A (ja) 1988-10-21
CA1336528C (fr) 1995-08-01
DE3876836T2 (de) 1993-05-06
FR2612778B1 (fr) 1991-10-18
FR2612778A1 (fr) 1988-09-30
DE3876836D1 (de) 1993-02-04
ES2052752T3 (es) 1994-07-16

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee