DE3874056T2 - Chinolinderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen, die sie enthalten. - Google Patents

Chinolinderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen, die sie enthalten.

Info

Publication number
DE3874056T2
DE3874056T2 DE8888306583T DE3874056T DE3874056T2 DE 3874056 T2 DE3874056 T2 DE 3874056T2 DE 8888306583 T DE8888306583 T DE 8888306583T DE 3874056 T DE3874056 T DE 3874056T DE 3874056 T2 DE3874056 T2 DE 3874056T2
Authority
DE
Germany
Prior art keywords
contain
production
6alkylthio
6alkoxy
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888306583T
Other languages
English (en)
Other versions
DE3874056D1 (de
Inventor
Robert John Ife
Thomas Henry Brown
Colin Andrew Leach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Intercredit BV
Original Assignee
SmithKline Beecham Intercredit BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Intercredit BV filed Critical SmithKline Beecham Intercredit BV
Publication of DE3874056D1 publication Critical patent/DE3874056D1/de
Application granted granted Critical
Publication of DE3874056T2 publication Critical patent/DE3874056T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE8888306583T 1987-07-24 1988-07-19 Chinolinderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen, die sie enthalten. Expired - Fee Related DE3874056T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878717644A GB8717644D0 (en) 1987-07-24 1987-07-24 Compounds

Publications (2)

Publication Number Publication Date
DE3874056D1 DE3874056D1 (de) 1992-10-01
DE3874056T2 true DE3874056T2 (de) 1993-01-07

Family

ID=10621289

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888306583T Expired - Fee Related DE3874056T2 (de) 1987-07-24 1988-07-19 Chinolinderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen, die sie enthalten.

Country Status (10)

Country Link
US (1) US5051508A (de)
EP (1) EP0307078B1 (de)
JP (1) JPS6440482A (de)
AT (1) ATE79880T1 (de)
AU (1) AU1920088A (de)
DE (1) DE3874056T2 (de)
DK (1) DK414488A (de)
GB (1) GB8717644D0 (de)
PT (1) PT88033B (de)
ZA (1) ZA885311B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8901430D0 (en) * 1989-01-23 1989-03-15 Smithkline Beckman Intercredit Compounds
CA2011086A1 (en) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
GB8928281D0 (en) * 1989-12-14 1990-02-21 Smith Kline French Lab Compounds
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
KR100187475B1 (ko) * 1996-05-17 1999-05-01 이서봉 1-아릴-4-옥소 피롤로(3,2-c)퀴놀린 유도체의 제조방법
KR100251522B1 (ko) * 1997-08-13 2000-08-01 김충섭 할로알콕시기를 함유하는 피롤[3,2-c]퀴놀린 유도체 및 약학적으로 허용되는 그의 염
WO2000001696A1 (en) * 1998-07-02 2000-01-13 Korea Research Institute Of Chemical Technology 3-ALKYLPYRROLO[3,2-c]QUINOLINE DERIVATIVES
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
GB0211649D0 (en) 2002-05-21 2002-07-03 Novartis Ag Organic compounds
EA009985B1 (ru) 2003-03-10 2008-04-28 Никомед Гмбх Новый способ получения рофлумиласта
EP1974730A1 (de) 2003-11-03 2008-10-01 AstraZeneca AB Imidazo[1,2-a]pyridin-Derivate zur Behandlung von Schlafstörungen durch stummen gastroösophagealen Reflux
EP1861074B1 (de) * 2005-03-16 2013-04-24 Takeda GmbH Geschmacksmaskierte dosierform von roflumilast
GB0522715D0 (en) 2005-11-08 2005-12-14 Helperby Therapeutics Ltd New use
GB0709513D0 (en) * 2007-05-17 2007-06-27 Helperby Therapeutics Ltd Topical formulations
WO2023003497A1 (ru) * 2021-07-23 2023-01-26 Общество С Ограниченной Ответственностью "Валента-Интеллект" Соединения с лизосомотропной и противовирусной активностью
WO2023064857A1 (en) 2021-10-14 2023-04-20 Incyte Corporation Quinoline compounds as inhibitors of kras

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2691023A (en) * 1952-05-26 1954-10-05 Schenley Ind Inc Dihydropyrrolo-(3.2-c) quinoline derivatives
GB725745A (en) * 1952-05-26 1955-03-09 Bayer Ag Pyrrolinoquinolines and processes for making same
GB1492029A (en) * 1974-01-30 1977-11-16 Bellon R Lab 4-oxo-1,4-dihydro-1,6-benzo-(h)-naphthyridine-3-carboxylic acid derivatives useful as anti-bacterial agents and their preparation

Also Published As

Publication number Publication date
ATE79880T1 (de) 1992-09-15
DE3874056D1 (de) 1992-10-01
DK414488D0 (da) 1988-07-22
PT88033B (pt) 1995-03-31
EP0307078A1 (de) 1989-03-15
ZA885311B (en) 1989-07-26
GB8717644D0 (en) 1987-09-03
PT88033A (pt) 1989-06-30
EP0307078B1 (de) 1992-08-26
DK414488A (da) 1989-01-25
AU1920088A (en) 1989-01-27
JPS6440482A (en) 1989-02-10
US5051508A (en) 1991-09-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee