DE3870016D1 - Mischungen polarer und neutraler lipide zur protektion des magen-darm-traktes. - Google Patents
Mischungen polarer und neutraler lipide zur protektion des magen-darm-traktes.Info
- Publication number
- DE3870016D1 DE3870016D1 DE8888301336T DE3870016T DE3870016D1 DE 3870016 D1 DE3870016 D1 DE 3870016D1 DE 8888301336 T DE8888301336 T DE 8888301336T DE 3870016 T DE3870016 T DE 3870016T DE 3870016 D1 DE3870016 D1 DE 3870016D1
- Authority
- DE
- Germany
- Prior art keywords
- mixtures
- neutral lipids
- compositions
- saturated
- stomestyle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 7
- 150000002632 lipids Chemical class 0.000 title abstract 3
- 230000007935 neutral effect Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 150000003904 phospholipids Chemical class 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- 208000022559 Inflammatory bowel disease Diseases 0.000 abstract 1
- 208000008469 Peptic Ulcer Diseases 0.000 abstract 1
- 229930182558 Sterol Natural products 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 208000011906 peptic ulcer disease Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003432 sterols Chemical class 0.000 abstract 1
- 235000003702 sterols Nutrition 0.000 abstract 1
- 150000003626 triacylglycerols Chemical class 0.000 abstract 1
- 230000001562 ulcerogenic effect Effects 0.000 abstract 1
- 230000002408 ulcerprotective effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/015,394 US4918063A (en) | 1987-02-17 | 1987-02-17 | Methods and compositions employing unique mixtures of polar and neutral lipids for protecting the gastrointestinal tract |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3870016D1 true DE3870016D1 (de) | 1992-05-21 |
Family
ID=21771153
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8888301336T Expired - Lifetime DE3870016D1 (de) | 1987-02-17 | 1988-02-17 | Mischungen polarer und neutraler lipide zur protektion des magen-darm-traktes. |
Country Status (8)
Country | Link |
---|---|
US (1) | US4918063A (de) |
EP (1) | EP0287198B1 (de) |
JP (1) | JP2820688B2 (de) |
AT (1) | ATE74758T1 (de) |
CA (1) | CA1310909C (de) |
DE (1) | DE3870016D1 (de) |
ES (1) | ES2038285T3 (de) |
GR (1) | GR3004396T3 (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5032585A (en) * | 1987-02-17 | 1991-07-16 | Board Of Regents, The University Of Texas System | Methods and compositions employing unique mixtures of polar and neutral lipids for surfactant replacement therapy |
US5811119A (en) * | 1987-05-19 | 1998-09-22 | Board Of Regents, The University Of Texas | Formulation and use of carotenoids in treatment of cancer |
JP3691054B2 (ja) * | 1992-01-16 | 2005-08-31 | ボード、オブ、リージェンツ、ザ、ユニバーシティー、オブ、テキサス、システム | 癌の治療におけるカロチノイド類の処方及び用法 |
US5229137A (en) * | 1992-05-06 | 1993-07-20 | Brigham And Women's Hospital, Inc. | Methods and pharmaceutical compositions for treating episodic heartburn |
US5478819A (en) * | 1993-06-23 | 1995-12-26 | Simo Tarpila | Phospholipid composition and use thereof |
US5955451A (en) * | 1995-05-12 | 1999-09-21 | The University Of Texas System Board Of Regents | Methods of enhancing the therapeutic activity of NSAIDS and compositions of zwitterionic phospholipids useful therein |
US6080787A (en) * | 1997-02-21 | 2000-06-27 | Abbott Laboratories | Methods for reducing the incidence of necrotizing enterocolitis |
ES2219871T3 (es) * | 1997-02-21 | 2004-12-01 | Abbott Laboratories | Procedimiento y composiciones que sirven para limitar la frecuencia de la enterocolitis necrotizante del recien nacido. |
US7413759B2 (en) * | 1998-05-21 | 2008-08-19 | Beech-Nut Nutrition Corporation | Method of enhancing cognitive ability in infant fed DHA containing baby-food compositions |
US6579551B1 (en) | 1998-05-21 | 2003-06-17 | Beech-Nut Nutrition Corporation | Baby-food compositions containing egg yolk and methods therefor |
US7141266B2 (en) * | 1998-05-21 | 2006-11-28 | Beech-Nut Nutrition Corporation | Baby-food compositions enhancing visual acuity and methods therefor |
US6149964A (en) * | 1998-05-21 | 2000-11-21 | Beech-Nut Nutrition Corporation | Egg yolk-containing baby food compositions and methods therefor |
ATE305235T1 (de) | 1998-12-22 | 2005-10-15 | Unilever Nv | Kosmetische verwendung von petroselinsäure |
WO2001076577A2 (en) | 2000-04-07 | 2001-10-18 | The Board Of Regents Of The University Of Texas System | Unique compositions of zwitterionic phospholipids and bisphosphonates and use of the compositions as bisphosphate delivery systems with reduced gi toxicity |
US20040077604A1 (en) | 2001-12-19 | 2004-04-22 | Lenard Lichtenberger | Method and compositions employing formulations of lecithin oils and nsaids for protecting the gastrointestinal tract and providingenhanced therapeutic activity |
US20100173876A1 (en) * | 2000-12-19 | 2010-07-08 | The Board Of Regents Of The University Of Texas System | Oil-based nsaid compositions and methods for making and using same |
US20080051373A1 (en) * | 2003-07-31 | 2008-02-28 | The Board Of Regents Of The University Of Texas System | Parenteral preparations of GI-safer phospholipid-associated anti-inflammatories and methods of preparation and use |
WO2005027933A1 (en) * | 2003-09-23 | 2005-03-31 | The Corporation Of The Trustees Of The Order Of The Sisters Of Mercy In Queensland | Unsaturated phosphatidylcholines and uses thereof |
ATE470435T1 (de) * | 2003-11-03 | 2010-06-15 | Yissum Res Dev Co | Verfahren zur auswahl von kationischen oder anionischen liposomen zur behandlung einer schleimhautmembran und diese enthaltendes set |
CN102988373A (zh) * | 2006-07-19 | 2013-03-27 | 德克萨斯大学系统董事会 | 用于治疗炎性肠病的磷脂与含有5-氨基水杨酸之药物的制备物 |
EP2172203A1 (de) * | 2008-09-17 | 2010-04-07 | Giuliani S.P.A. | Pharmazeutisches Zusammensetzung zur Behandlung von Magen-Darm-Reizungsstörungen |
US8471047B1 (en) * | 2010-12-09 | 2013-06-25 | Surfatech Corporation | Mixed glyceryl esters |
WO2013049749A2 (en) | 2011-09-29 | 2013-04-04 | Plx Pharma Inc. | pH DEPENDENT CARRIERS FOR TARGETED RELEASE OF PHARMACEUTICALS ALONG THE GASTROINTESTINAL TRACT, COMPOSITIONS THEREFROM, AND MAKING AND USING SAME |
EP2848251B1 (de) * | 2013-09-12 | 2017-04-19 | King Saud University | Auszüge und isolierte Verbindungen von Cakile arabica für die Behandlung von Geschwüren |
WO2021195319A1 (en) | 2020-03-26 | 2021-09-30 | Plx Opco Inc. | PHARMACEUTICAL CARRIERS CAPABLE OF pH DEPENDENT RECONSTITUTION AND- METHODS FOR MAKING AND USING SAME |
CN112516129B (zh) * | 2021-01-09 | 2022-04-29 | 兰州大学 | 反式1,3-二亚油精在制备治疗胃癌药物、健胃药物、保健品和食品中的应用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2556592C2 (de) * | 1975-12-16 | 1986-10-09 | A. Nattermann & Cie GmbH, 5000 Köln | Arzneimittelzubereitungen auf Basis öliger Lösungen von Phospholipiden |
DE2856333C2 (de) * | 1978-12-27 | 1983-09-22 | A. Nattermann & Cie GmbH, 5000 Köln | Oral einnehmbare Arzneimittel mit entzündungshemmender Wirkung |
DE3028074C2 (de) * | 1980-07-22 | 1983-12-08 | Kurt Kampffmeyer Mühlenvereinigung KG, 2000 Hamburg | Verfahren zur Herstellung eines lecithinhaltigen Produktes |
IL63734A (en) * | 1981-09-04 | 1985-07-31 | Yeda Res & Dev | Lipid fraction,its preparation and pharmaceutical compositions containing same |
EP0092121B1 (de) * | 1982-04-12 | 1987-12-16 | Board Of Regents, The University Of Texas System | Verfahren und Zusammensetzungen zur Behandlung von Magen- und Darm-Ulcus |
DE3369644D1 (en) * | 1982-11-22 | 1987-03-12 | Teijin Ltd | Artificial lung surfactant and remedy for respiratory distress syndrome containing it as active principle |
DE3346525C2 (de) * | 1983-12-22 | 1987-03-19 | A. Nattermann & Cie GmbH, 5000 Köln | Pharmazeutische Zubereitung mit speziellen 1,2-Diacyl-glycero-3-phosphocholinen zur Behandlung von Erkrankungen im Magen-Darmbereich |
CA1296640C (en) * | 1985-07-26 | 1992-03-03 | Meir Shinitzky | Special lipid mixture for membrane fluidization |
-
1987
- 1987-02-17 US US07/015,394 patent/US4918063A/en not_active Expired - Lifetime
-
1988
- 1988-02-16 CA CA000558958A patent/CA1310909C/en not_active Expired - Lifetime
- 1988-02-17 EP EP88301336A patent/EP0287198B1/de not_active Expired - Lifetime
- 1988-02-17 ES ES198888301336T patent/ES2038285T3/es not_active Expired - Lifetime
- 1988-02-17 JP JP63036455A patent/JP2820688B2/ja not_active Expired - Fee Related
- 1988-02-17 DE DE8888301336T patent/DE3870016D1/de not_active Expired - Lifetime
- 1988-02-17 AT AT88301336T patent/ATE74758T1/de not_active IP Right Cessation
-
1992
- 1992-04-16 GR GR920400715T patent/GR3004396T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ATE74758T1 (de) | 1992-05-15 |
JP2820688B2 (ja) | 1998-11-05 |
JPS63301824A (ja) | 1988-12-08 |
EP0287198A3 (en) | 1988-11-17 |
ES2038285T3 (es) | 1993-07-16 |
EP0287198B1 (de) | 1992-04-15 |
US4918063A (en) | 1990-04-17 |
EP0287198A2 (de) | 1988-10-19 |
CA1310909C (en) | 1992-12-01 |
GR3004396T3 (de) | 1993-03-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |