DE3864348D1 - Mikropartikel, bestehend aus einem biodegradierbaren, die freisetzung eines antimalaria-wirkstoffs kontrollierenden polymer, diese enthaltende pharmazeutische zusammensetzungen und ihr herstellungsverfahren. - Google Patents
Mikropartikel, bestehend aus einem biodegradierbaren, die freisetzung eines antimalaria-wirkstoffs kontrollierenden polymer, diese enthaltende pharmazeutische zusammensetzungen und ihr herstellungsverfahren.Info
- Publication number
- DE3864348D1 DE3864348D1 DE8888401965T DE3864348T DE3864348D1 DE 3864348 D1 DE3864348 D1 DE 3864348D1 DE 8888401965 T DE8888401965 T DE 8888401965T DE 3864348 T DE3864348 T DE 3864348T DE 3864348 D1 DE3864348 D1 DE 3864348D1
- Authority
- DE
- Germany
- Prior art keywords
- microparticles
- release
- pharmaceutical compositions
- biodegradable polymer
- antimalaria
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8710802A FR2618674B1 (fr) | 1987-07-30 | 1987-07-30 | Microparticules comportant un polymere biodegradable controlant la liberation d'un principe actif antimalarique, compositions pharmaceutiques en comprenant et procede de preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3864348D1 true DE3864348D1 (de) | 1991-09-26 |
Family
ID=9353715
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8888401965T Expired - Fee Related DE3864348D1 (de) | 1987-07-30 | 1988-07-28 | Mikropartikel, bestehend aus einem biodegradierbaren, die freisetzung eines antimalaria-wirkstoffs kontrollierenden polymer, diese enthaltende pharmazeutische zusammensetzungen und ihr herstellungsverfahren. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4897267A (de) |
EP (1) | EP0301969B1 (de) |
JP (1) | JPS6442433A (de) |
AT (1) | ATE66372T1 (de) |
CA (1) | CA1329549C (de) |
DE (1) | DE3864348D1 (de) |
ES (1) | ES2024668B3 (de) |
FR (1) | FR2618674B1 (de) |
GR (1) | GR3002601T3 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2644462B1 (fr) * | 1988-09-23 | 1993-07-09 | Ire Celltarg Sa | Nouveaux composes actifs sur les formes tissulaires de la malaria et procede de preparation |
LU87410A1 (fr) * | 1988-12-20 | 1990-07-10 | Cird | Composition cosmetique ou pharmaceutique contenant des microspheres de polymeres ou de corps gras chargees d'au moins un produit actif |
FR2659554B1 (fr) | 1990-03-16 | 1994-09-30 | Oreal | Composition pour le traitement cosmetique et/ou pharmaceutique des couches superieures de l'epiderme par application topique sur la peau et procede de preparation correspondant. |
US5766635A (en) * | 1991-06-28 | 1998-06-16 | Rhone-Poulenc Rorer S.A. | Process for preparing nanoparticles |
US5610753A (en) * | 1991-12-12 | 1997-03-11 | Eastman Kodak Company | Optical design of laser scanner to reduce thermal sensitivity |
ZA93929B (en) * | 1992-02-18 | 1993-09-10 | Akzo Nv | A process for the preparation of biologically active materialcontaining polymeric microcapsules. |
US5514378A (en) * | 1993-02-01 | 1996-05-07 | Massachusetts Institute Of Technology | Biocompatible polymer membranes and methods of preparation of three dimensional membrane structures |
US6689608B1 (en) | 1993-02-01 | 2004-02-10 | Massachusetts Institute Of Technology | Porous biodegradable polymeric materials for cell transplantation |
US6090925A (en) | 1993-03-09 | 2000-07-18 | Epic Therapeutics, Inc. | Macromolecular microparticles and methods of production and use |
US5981719A (en) | 1993-03-09 | 1999-11-09 | Epic Therapeutics, Inc. | Macromolecular microparticles and methods of production and use |
US5569468A (en) * | 1994-02-17 | 1996-10-29 | Modi; Pankaj | Vaccine delivery system for immunization, using biodegradable polymer microspheres |
US5417982A (en) * | 1994-02-17 | 1995-05-23 | Modi; Pankaj | Controlled release of drugs or hormones in biodegradable polymer microspheres |
US5626862A (en) | 1994-08-02 | 1997-05-06 | Massachusetts Institute Of Technology | Controlled local delivery of chemotherapeutic agents for treating solid tumors |
US5654007A (en) * | 1995-06-07 | 1997-08-05 | Inhale Therapeutic Systems | Methods and system for processing dispersible fine powders |
FR2764514B1 (fr) * | 1997-06-13 | 1999-09-03 | Biopharmex Holding Sa | Implant injectable en sous-cutane ou intradermique a bioresorbabilite controlee pour la chirurgie reparatrice ou plastique et la dermatologie esthetique |
US6306425B1 (en) | 1999-04-09 | 2001-10-23 | Southern Research Institute | Injectable naltrexone microsphere compositions and their use in reducing consumption of heroin and alcohol |
ES2230154T3 (es) | 1999-08-27 | 2005-05-01 | Southern Research Institute | Composiciones inyectables de buprenorfina y su utilizacion para reduccion del consumo de heroina y alcohol. |
CN1194704C (zh) * | 2001-11-12 | 2005-03-30 | 华东理工大学 | 含有活性药物、主链中具有氨基酸的聚酯及其制备方法 |
JP4961213B2 (ja) * | 2004-01-21 | 2012-06-27 | ザ・スクール・オブ・ファーマシー | マイクロ粒子の製造方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL263733A (de) * | 1960-04-19 | 1900-01-01 | ||
BE755975A (fr) * | 1969-09-10 | 1971-03-10 | Dann Otto | Nouveaux derives de la quinoleine, compositions pharmaceutiquesen contenant et leur obtention |
US3773919A (en) * | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
US3663552A (en) * | 1970-04-09 | 1972-05-16 | American Home Prod | 2'-substituted-cinchona alkaloids |
DE2748333A1 (de) * | 1977-10-28 | 1979-05-03 | Hoechst Ag | Mittel gegen malaria |
US4416872A (en) * | 1982-03-17 | 1983-11-22 | The United States Of America As Represented By The Secretary Of The Army | Treatment of malaria with liposomes containing 8-aminoquinoline derivatives and glycoconjugates |
CA1196864A (en) * | 1983-06-10 | 1985-11-19 | Mattheus F.A. Goosen | Controlled release of injectable and implantable insulin compositions |
-
1987
- 1987-07-30 FR FR8710802A patent/FR2618674B1/fr not_active Expired - Fee Related
-
1988
- 1988-07-28 AT AT88401965T patent/ATE66372T1/de not_active IP Right Cessation
- 1988-07-28 DE DE8888401965T patent/DE3864348D1/de not_active Expired - Fee Related
- 1988-07-28 US US07/225,395 patent/US4897267A/en not_active Expired - Fee Related
- 1988-07-28 EP EP88401965A patent/EP0301969B1/de not_active Expired - Lifetime
- 1988-07-28 CA CA000573303A patent/CA1329549C/fr not_active Expired - Fee Related
- 1988-07-28 ES ES88401965T patent/ES2024668B3/es not_active Expired - Lifetime
- 1988-07-29 JP JP63188520A patent/JPS6442433A/ja active Pending
-
1991
- 1991-08-22 GR GR91401230T patent/GR3002601T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ATE66372T1 (de) | 1991-09-15 |
EP0301969B1 (de) | 1991-08-21 |
GR3002601T3 (en) | 1993-01-25 |
FR2618674A1 (fr) | 1989-02-03 |
US4897267A (en) | 1990-01-30 |
JPS6442433A (en) | 1989-02-14 |
EP0301969A1 (de) | 1989-02-01 |
ES2024668B3 (es) | 1992-03-01 |
CA1329549C (fr) | 1994-05-17 |
FR2618674B1 (fr) | 1990-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |