DE3862843D1 - Kationische komplexe des technetiums-99m. - Google Patents

Kationische komplexe des technetiums-99m.

Info

Publication number
DE3862843D1
DE3862843D1 DE8888309235T DE3862843T DE3862843D1 DE 3862843 D1 DE3862843 D1 DE 3862843D1 DE 8888309235 T DE8888309235 T DE 8888309235T DE 3862843 T DE3862843 T DE 3862843T DE 3862843 D1 DE3862843 D1 DE 3862843D1
Authority
DE
Germany
Prior art keywords
cationic
complexes
ligands
technology
technology complexes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8888309235T
Other languages
English (en)
Inventor
Kowk Wai Chiu
James Duncan Kelly
Ian Andrew Latham
David Vaughan Griffiths
Peter Gerald Edwards
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare Ltd
Original Assignee
Amersham International PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10624861&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3862843(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amersham International PLC filed Critical Amersham International PLC
Application granted granted Critical
Publication of DE3862843D1 publication Critical patent/DE3862843D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/50—Organo-phosphines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic System
    • C07F13/005—Compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/50—Organo-phosphines
    • C07F9/5027—Polyphosphines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/66—Arsenic compounds
    • C07F9/70—Organo-arsenic compounds
    • C07F9/72—Aliphatic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
DE8888309235T 1987-10-06 1988-10-04 Kationische komplexe des technetiums-99m. Expired - Lifetime DE3862843D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878723438A GB8723438D0 (en) 1987-10-06 1987-10-06 Cationic complexes of technetium-99m

Publications (1)

Publication Number Publication Date
DE3862843D1 true DE3862843D1 (de) 1991-06-20

Family

ID=10624861

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888309235T Expired - Lifetime DE3862843D1 (de) 1987-10-06 1988-10-04 Kationische komplexe des technetiums-99m.

Country Status (12)

Country Link
US (1) US4916214A (de)
EP (1) EP0311352B1 (de)
JP (1) JPH0737472B2 (de)
KR (1) KR970011165B1 (de)
AT (1) ATE63559T1 (de)
CA (1) CA1336438C (de)
DE (1) DE3862843D1 (de)
DK (1) DK171487B1 (de)
ES (1) ES2037234T3 (de)
GB (1) GB8723438D0 (de)
IL (1) IL87944A (de)
WO (1) WO1989003388A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8808414D0 (en) * 1988-04-11 1988-05-11 Amersham Int Plc Ligands & cationic complexes thereof with technetium-99m
GB8902362D0 (en) * 1989-02-03 1989-03-22 Amersham Int Plc Cationic complexes of technetium-99m
US4917879A (en) * 1989-05-19 1990-04-17 University Of Cincinnati 99MTC(III) myocardial imaging agents that are effective in humans
US6001979A (en) 1989-08-29 1999-12-14 Nycomed Amersham Plc Cores for technetium radiopharmaceuticals
DD291327A5 (de) * 1989-12-29 1991-06-27 �������@����@�K@��@��k�� Myokardgaengige technetium-komplexverbindungen und verfahren zu deren herstellung
GB2242189A (en) * 1990-03-23 1991-09-25 Shell Int Research Bidentate ligands and their precursors
US5541289A (en) * 1994-03-30 1996-07-30 Washington University Phosphine containing amino acids and peptides and methods of preparing and using same
US5834456A (en) * 1996-02-23 1998-11-10 The Dow Chemical Company Polyazamacrocyclofluoromonoalkylphosphonic acids, and their complexes, for use as contrast agents
IT1286879B1 (it) * 1996-11-21 1998-07-17 Consiglio Nazionale Ricerche Leganti 1,3-difosfinopropanici e complessi da essi formati con metalli di transizione,loro preparazione e uso
DK0949265T3 (da) * 1996-12-18 2003-08-11 Nihon Mediphysics Co Ltd Nitrid-heterokomplekser af radioaktive overgangsmetaller
US6733767B2 (en) * 1998-03-19 2004-05-11 Merck & Co., Inc. Liquid polymeric compositions for controlled release of bioactive substances
US6794553B2 (en) * 2001-11-09 2004-09-21 Shell Oil Company Process for the telomerization of a conjugated diene, catalyst and bidentate ligand useful therein
EP2899195A1 (de) 2014-01-28 2015-07-29 ROTOP Pharmaka AG Stabilisierte Form von Tetrofosmin und seine Verwendung

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1917884A1 (de) * 1968-04-08 1969-10-16 Toa Gosei Chem Ind Verfahren zur Herstellung von 1-Buten-2,3,4-tricarbonsaeureestern
US4387087A (en) * 1980-04-18 1983-06-07 Research Corporation Cationic lipophilic complexes of 99m Tc and their use for myocardial and hepatobiliary imaging
US4489054A (en) * 1980-04-18 1984-12-18 Research Corporation Cationic lipophilic complexes of 99m Tc and their use for myocardial and hepatobiliary imaging
US4451450A (en) * 1981-10-15 1984-05-29 New England Nuclear Corporation Cationic compounds useful for making radiodiagnostic agents
US4374821A (en) * 1982-06-28 1983-02-22 E. R. Squibb & Sons, Inc. Myocardial imaging agent and method
US4481184A (en) * 1983-02-14 1984-11-06 E. R. Squibb & Sons, Inc. Cationic technetium (I) complexes
US4526776A (en) * 1983-04-15 1985-07-02 E. I. Du Pont De Nemours & Company Cationic cyanato and thiocyanato complexes useful as radiodiagnostic agents
US4795626A (en) * 1985-05-10 1989-01-03 University Of Cincinnati 99m Tc.sup.(III) myocardial imaging agents which are non-reducable in vivo
US4765971A (en) * 1985-05-31 1988-08-23 Mallinckrodt, Inc. Technetium (Tc-99m)-arene complexes useful in myocardial imaging
GB8531296D0 (en) * 1985-12-19 1986-01-29 Amersham Int Plc Cationic complexes of technetium

Also Published As

Publication number Publication date
ES2037234T3 (es) 1993-06-16
ATE63559T1 (de) 1991-06-15
IL87944A (en) 1994-07-31
GB8723438D0 (en) 1987-11-11
KR970011165B1 (ko) 1997-07-08
JPH01128990A (ja) 1989-05-22
JPH0737472B2 (ja) 1995-04-26
WO1989003388A1 (en) 1989-04-20
KR890701601A (ko) 1989-12-21
DK171487B1 (da) 1996-11-25
CA1336438C (en) 1995-07-25
DK266689D0 (da) 1989-06-01
US4916214A (en) 1990-04-10
EP0311352A1 (de) 1989-04-12
DK266689A (da) 1989-06-01
EP0311352B1 (de) 1991-05-15
IL87944A0 (en) 1989-03-31

Similar Documents

Publication Publication Date Title
DE3862843D1 (de) Kationische komplexe des technetiums-99m.
DE19475010I2 (de) Durch Estergruppen substituierte Diamindithiole und davon abgeleitete radioaktiv markierte Komplexe
BR1100621A (pt) Compostos
HU903963D0 (en) Condensed heterocyclic compounds, their preparation and utilization
HUT64768A (en) Polyaza-macrocyclic-compounds and metal ionic complexes thereof
ES2091323T3 (es) Medios de contraste.
ES2060002T3 (es) Compuestos formadores de quelatos para la complejacion de isotopos radiactivos, sus complejos con metales, asi como su utilizacion en diagnostico y terapia.
FI895516A0 (fi) Medel foer att hindra foerstoering av benmaerg.
DE68925594T2 (de) Liganden und ihre Komplexe mit Technetium-99m
MY101841A (en) Insecticidal trifluormethyl alkane derivatives.
CA2323150A1 (en) New porphyrins and their use
WO1994008949A3 (en) Metal-oxime chelates for use as radiopharmaceutical agents
GB8919488D0 (en) New cores for technetium radiopharmaceuticals
DK464586A (da) Phosphorforbindelser
CA2037007A1 (en) 2,2'-bis[di-(3,5-dialkylphenyl)phosphino]-1,1'-binaphthyl and transition metal complex containing the same as ligand
PT75637B (en) Process for the preparation of substituted diamides of the hydroxy-malonic acid with pesticidal effect
ATE244023T1 (de) Ternäre radiopharmazeutische komplexe
ZA881430B (de)
ATE55389T1 (de) 99mtc(iii)-agenzien zur myokardialen darstellung, in vivo nichtreduzierbar.
SE8500307D0 (sv) Nya, antiviruella medel
DE69132772T2 (de) Herstellung von Borsäurederivaten
EP0369749A3 (de) Antitumor-Verbindungen
FR2429786A1 (fr) Sulfonyl-urees, leurs procedes de preparation et leur application en therapeutique
EP0266910A3 (de) Tc-99m-Kationkomplexe
FR2356699A1 (fr) Pigments azomethiniques metalliferes heterocycliques

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: HAMMONDS RECHTSANWAELTE PATENTANWAELTE, 80539 MUENCHEN

8327 Change in the person/name/address of the patent owner

Owner name: GE HEALTHCARE LTD., LITTLE CHALFONT, BUCKINGHAMSHI